Average Rating: 1.8 (69 Ratings)

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 Type: Rx Drug

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on TIROSINT: Reviews Summary  |  Drug Safety Information

 1  Hypothyroidism I feel like I'm being poisoned! My doctor won't listen. Shakes, weak, tired, drained Poison F 60 21 days
13mcg 1X D
 2  Hypothyroid after Graves' Disease Extremely nervous shortly after taking some; hit me very strongly--probably due to the gelcap form of it & few ingredients, so some of us will absorb & use it faster (I was told, later on). Couldn't sleep well with it; many symptoms of high and low thyroid, at the same time. I only stuck with it so long because I was out of options, and it did seem to want to help me better in the first months with some symptoms...but still very hard on me to take. Dr. had me take it with beta-blockers for awhile, just so I could try to get benefit from the Tirosint. It was still hard. In the end, I couldn't take it any more. I felt it was contributing to periods that wouldn't stop, and were too heavy. That was final straw. That did eventually get better after getting on some natural thyroid drug, although that failed me in different ways, later on. I like the idea of Tirsoint, but it was too strong for me to handle, even spreading it out throughout the day with five 13 mcg. gelcaps. I was only able to do this because of Tirosint's Patient Assistance program, which was very helpful at the time and paid for me to try this kind of dosing (I couldn't have afforded it, otherwise, so thanks to them for giving me the chance.) I really wanted this drug to work, but for me, I just kept getting hit with how super-strong it was on me. I am out of options, once again, and have to keep working with various thyroid meds that have failed me, already. We need more options. Only thyroid drug that helped me well isn't made anymore. It was an older version of Synthroid--manufacturers made changes to Synthroid in 1982-83, and I haven't done well, since, on anything. And I've tried so many of these drugs, natural & synthetic, at different doses, etc. Maybe Tirosint can work for some; I hope so, but for me it was just too much to deal with. F 58 4 years
13 mcg 5X D
 2  Hypothyroidism Decresed dose in August 2021 from 25mcg to 13.9mcg. eyes are causing so much trouble double vision, floaters, dry, skin extremely dry and itchy, swollen fingers, hands wrists ankles knees, headaches, tremors, heart palpitations, extreme debilitating (at times) anxiety but no one really believes me. Extreme fatigue! Just overall bad feeling even though levels are within mid normal range... Idk what to do! So sick of feeling horrible day to day. Some days are good but so exhausted for days and days after good days, can't function! Memory is horrible. Idk if its Tirosint or not. But I do not feel well at all. So shaky and irritable that I don't want to go around ppl. F 41 60 days
13.9mcg 1X D
 1  Thyroidectomy/cancer Pains all over body, feet, ankle, legs swollen and couldn't walk especially in the morning before getting out of bed. Chest pain and difficulty breathing, horrible toe pain. I really was hoping this medicine was going to work because I've tried so many meds and my body doesn't want any medication for thyroid. Hair loss, hot feet mostly big toes and ankles. Had to discontinue the medication. Hope this helps others. Literally cannot take F 47 60 days
75 1X D
 1  Hashimotos Second day of taking Tirosint when both hip joints began to hurt. At first, I just thought it was something that would pass. As time went on the pain increased and involved my lower back. Now the pain is extreme and I limp while walking and it wakes me at night. I quit Tiro 2 days ago and am hoping this subsides soon. It is debilitating! M 68 21 days
100Mcg 1X D
 1  Hypothyroid Off balance, dizzy, heart palpitations and pounding, toe neuropathy, swelling feet, numbness in tongue, left hand and arm, F 64 60 days
25 1X D
 2  Lactose intolerance Took first dose today (Friday). I felt fine for an hour or two. Headache started. Sinus pressure and intense pressure behind eyes. Urgency when my bowels moved. Headache gradually got worse. Bones in face ached as as face muscles. Sore muscles all over. Weakness in right back rib cage. Chest pains. Pain in pelvic bones. Bladder pain and either right ovary pain or appendix pain. Breast tenderness. Aching pain over upper left quadrant of thyroid. Dry cough. Blurred vision. But helped my hearing. I'm sure this medicine is beneficial. But not for me. F 28 1 days
75 1X D
 2  Thyroid cancer Horrible left foot pain, swelling all over my body, hands, feet, legs, face, dry eyes, nausea, vomiting, can barely walk. F 47 4 weeks
75Mg 1X D
 1  Hypothyroidism This was the worst thing ever after trying every other medication before this one this one gave severe severe severe feet pain where I couldn't walk. I tried it on three separate occasions and every single time hair re grew but feet pain kept coming back so went to Thyquidity. F 49 1 days
13 1X D
 1  Hypothyroidism I have extreme sensitivity to fillers/binders in medication and thought this is my solution since it's suppose to be "clean".... I recently was seen for terrible bilateral foot pain that's been going on approximately 4 weeks with no sign of injury, was also recently seen for irregular heartbeat, racing heart but all tests were normal, extreme restless legs at night, joint pain, insomnia, anxiety, gastric issues, eye changes, hair loss and increased migraines. My doctor said it could not be the medication since it's only levothyroxine, water and glycerin. My body says otherwise. Hoping to get into an endocrinologist soon. I'm stopping the medication to see if I have improvement. I feel like I'm losing my mind. I feel for everyone having issues. F 47 6 months
50 mcg 1X D
 1  Hypothyroidism only have upper thyroid Sensitivities started last few months. Hot burning feet in toes and palms of hands red n swollen fingers sore Also muscle cramps eyes burning watering . Had my whole body react today had to take EPI pen ! No more ever!! F 64 18 months
137 1X D
 1  Hypothyroidism Started with left foot pain, after 4 weeks.... That grew to include knee & hip pain! Excruciating pain. Limp. And SEVERE DIARRHEA! Plus insomnia and generally felt unwell. My T4 shot up dramatically! I dropped Tirosint 2 days ago, and going back on Armour until I see my PCP. F 77 6 weeks
50 mg 1X D
 1  Hashimotos Thyroiditis Extreme fatigue, rashes on my face, joint pain, muscle weakness. 5-6 days a month I literally cannot function. I finally quit taking it two weeks ago and all of the horrible symptoms are almost gone. I took it today just to see if it was a coincidence. Within an hour I had horrific stomach pains and felt like I was on fire. I will never take this again. F 55 8 months
110 1X D
 1  Thyroidectomy I'm trying to be patient and scientific about the potential for this drug since my doctor seems to think it will work for me. I have had trouble stabilizing TSH, lots of ups and downs since cancer/removal in 2015, but it has been VERY difficult. This site is a game changer for me bc I realize I am not alone. I wish I could offer hope to all of you who are experiencing the horrible symptomology (debilitating joint pain, insomnia, anxiety, depression, frustration,...all of the above). But I can only thank you for taking the time to share your experiences. I am calling my doctor Monday. Pretty sure it IS poison. The worse part is that stating the truth makes you feel like a crazy person. You do feel like you are dying. Am I just on too strong of a dose? Doctor has dropped 3x (112, 100, 88 when I was mostly stabilized on 112 of generic Levo.) Time will tell. I'm even seeing a therapist now, after 47 years of no mental health issues. She wisely told me that I need to advocate for myself. I wish I could advocate for all of you. I can only say you're not alone. Don't let it beat you. There's too much beauty in this world. F 47 100 days
112, 100, 1X D
 3  Hashimoto Increased knee pain and flexibility. Increased pain in my feet numbness in my toes. Increased flare-ups in my hand joints. My numbers are in range and I still feel so exhausted with a heaviness in my body. Daily sharp headaches. Occasional dizziness. Fogginess in my head. Unable to process too much information at once. Decreased ability to handle stress well. Tirosint sent gel caps are better on my stomach. They do not cause my stomach to cramp up, but have caused my body much pain and dysfunction. I don't know what to do my body doesn't like armor or levothyroxine AKA synthroid. I'm only 52 and feel trapped in this body due to feeling like I am crippled. My symptoms started about a month and a half into taking this med. I switched from armor thyroid due to cardiac response. And before that I was taking synthroid tablet which was causing unbearable flares in my body as well. 52 11 months
125 mg 1X D
 1  Hashimotos Shortly after my father died, I went to my endocrinologist because I was feeling extreme fatigue and, of course, depression. Doc ran all the thyroid panels. My body was not absorbing Synthroid. He switch me to Tirosint. I have been beyond depressed since the switch. Depression worsened each year. Just this month I had suicidal thoughts every evening. This prescription ruined my life. F 56 2 years
137 1X D
 2  Hashimotoís/hypothyroid Extreme hair loss, problems with knees and pes anserine bursitis that wonít go away; insomnia (3-5 hours sleep a night), sometimes miss whole nights of sleep. Felt unbelievably wonderful first two days and then it went down hill. TSH still fluctuating even though it is supposed to be better at stabilizing. I am actually taking Tirosint Sol, the liquid form of Tirosint. I thought it was going to be a wonderful med finally. It is causing me a lot of problems I canít ignore, mainly hair loss, knee problems and chronic insomnia. F 61 7 months
100 mcg 1X D
 3  Hypothyriodism At first this medication was working very well with my energy and ended up thickening my hair which has always been thin, but i have many problems with this med. Problems i am having with it though is the fact that no matter how tired I am, I am always so shaky and breathing is hard. Wish i could rate this medication better but it has caused more harm then actual help. M 15 8 months
50 1X D
 1  Hashimotos Heart Palpitations that were frightening. Ended up in the hospital but told my heart is fine. Thyroid levels are normal too. Can't wait to get off Tirosint. It has been a complete nightmare. I also see on other reviews that people complain of joint pain. I also had this problem but didn't realize it could be from Tirosint. At one point, I could barely walk. F 62 7 months
50 1X D
 1  Hashimoto's After 6 days, my vision got blurry, could not see, whole body shaking, could not walk, blood pressure went to 197/97, heart rate 118, severe anxiety, stomach pain in pit of stomach. Severe reaction and 2 weeks later still trying to recover. F 65 6 days
25 mcg 1X D

TIROSINT  (LEVOTHYROXINE SODIUM):  Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer). This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.   (Sources: U.S. Centers for Medicare Services, FDA)