AROMASIN Reviews (EXEMESTANE)

Average Rating: 1.9 (145 Ratings)

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 AROMATASE INHIBITORS

 Type: Rx Drug

  

AROMASIN  (EXEMESTANE):  This medication is used to treat certain types of breast cancer (such as hormone-receptor-positive breast cancer) in women after menopause. Exemestane is also used to help prevent the cancer from returning. Some breast cancers are made to grow faster by a natural hormone called estrogen. Exemestane decreases the amount of estrogen the body makes and helps to slow or reverse the growth of these breast cancers. Exemestane is usually not used in women of childbearing age.   FDA Approval Date: 1999-10-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AROMASIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AROMASINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Stage 2 breast cancer Insomnia, nightly hot flashes, fatigue, severe bone pain, depression The insomnia and hot flashes were immediate, the bone pain developed after the first several months as did the fatigue and depression. My oncologist suggested I stop and consider another drug. It took about a month before the side effects left, and I have decided that quality of life is too important to go on one of the other 2 drugs. F 62 5 months
25mg 1X day
12/28/2014
 3  hi estrogen on testosterone therapy Fatigue and pain was a problem within 7 days of beginning 25mg daily. Brain fog, loss of motivation, stiffness, and just generally not feeling like doing anything, even easy daily tasks. Taking this to lower my estrogen levels after 6 months on testosterone replacement therapy. Testosterone is converted into estrogen in the male body and with testosterone replacement it sometimes gets converted at a higher rate leading to very high estrogen levels which can cause many issues from water retention, male breast development, and a higher risk of cardiovascular disease. 25mg per day dropped my estrogen to nearly zero. The body uses estrogen for many things, and getting it super low can cause many problems. Severe joint and bone pain, fatigue, depression, anxiety, sexual dysfunction are some of them. Fortunately, my doctor was very knowledgeable and had me switch to 12.5mg per day. After a month, I was still struggling, but not as bad. Estrogen levels tested as still being too low although not as low as before. So next I was told to use 12.5mg every other day. That proved to be the right dosage as it allowed my estrogen levels to balance out in the normal range for a male. Unfortunately for breast cancer patients, the goal is typically to get estrogen levels extremely low. I am not sure if it is the mechanism that the estrogen is lowered by with the drug, or if it is an issue of too little estrogen in the body for other functions to remain normal. But for my situation, once I got my estrogen levels in the normal range, the side effects were barely noticeable, compared to before when they made me feel incapacitated. M 39 60 days
12.5mg 1X O
12/14/2014
 1  Breast cancer After having it for 8 days I had to be hospitalized. High fever, ulcers in the mouth and severe headache. After lumpectomy I had four cycles of chemo and radiation.Then I had Tamoxifen for five years. After that my doctor asked me to start aromasin. F 47 8 days
25
12/8/2014
 1  Stage 3C Breast Cancer Crippling, terrible arthritis-like pain, insomnia, nausea, post-nasal drip, thinning hair on crown, skin rashes, fatigue hot flashes, blood clot in groin, and liver problems. Oh, and my favorite side effect? I gained 30-35 pounds in a matter of months & CAN'T get it off! I started taking the Aromatase Inhibitors in 2009. My docs tried to tell me that my bone-muscle-joint pain was because of my age (60s) and my weight. It was just ordinary arthritis they all said. Hogwash! I am so tired of doctors laying every health problem on my age or my weight when it is one or more of the drugs I am on. Here's how I know my symptoms are Aromasin drug-related: Every time I take an Aromasin Medication Vacation, most of my Aromasin side effects go away. And, I started on Arimdex and then Femara and had the SAME side effects. I stayed on Aromasin since there were no other options. I have not had a 1-month vacation from the Aromasin for 4 years, but when I did, my pain decreased. Since I reached my 5 years on this awful drug, the choice is mine to stay on it or go off. I decided to take another vacation. Within a week, my pain is nearly all gone and my other symptoms are also improving. I can't believe how much better I feel. I feel like I have my life back. I don't know if I will go back on Aromasin or not. What's the point of taking a drug that makes your daily life a hell? Not what I call a quality life. Why can't they make a drug with fewer side effects for a change? F 65 5 years
25 1X day
11/19/2014
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 1  breast cancer inductal stage2 I have degenerative arthritis to begin with. This is my 4th anti-estrogen medication. Each one bad, each one different side effects. This one is bad. Neck and lower back on fire. Wrists are snapping and experiencing 'shin split' type pain. It's been a year to date and I am 56 and yep, feeling like a million. Memory is shot. Tamox - oh Lord was the worst for sweats and vaginal lining deterioration. Does this madnes end. HELP us Dr's, Come up with something that helps and not have to hurt so much as well. They never told us that the 'after effects' of all of this would be so bad. I had a real bad 2 year bout 15 years ago with my neck and back. Ended up with several Dr's, specialists... a real painful - pain med existance I never want to revisit again but here it is. Yep sex drive - gone, youthful demeanor - gone, these meds...are thye worth it? I dont know sisters, I really dont. F 56 50 days
1X day
11/13/2014
Email
 1  Breast Cancer I cannot believe this drug was even approved by the FDA . It made my bone hurt so bad eventually I could not even get out of bed it was horrible, my regular doctor prescribed me hydrocodone for the pain I was in I am currently on tamoxifen and am very happy oh I forgot to tell you about the other side effects not sleeping, anxiety, my life was not worth living and I often wondered with the amount of money we give to cancer research the medications should be at least tolerable it's horrible to have to go through this and keep thinking if you don't take the medication your going to get cancer again. I have been very satisfied on tamoxifen and hope it remains this way for the remainder of my 5 years F 64 1 years
25 mg
10/29/2014
Email
 1  Stage lllB Lobule Breast Cancer Severe depression and insomnia. Joint pain, fatigue, and foggy brain. Stopped taking this drug due to side effects. Went through 6 anti-depression drugs and 3 sleep aids. Side effects got worse. I've been off of aromasin for 5 months and feel really good. Oncologist asked if I would try a different estrogen blocking drug, but I declined. I would rather feel good for a shorter period of time than stay on that awful drug. F 60 1 years
25mg 1X day
10/22/2014
Email
 1  Stage 0 Breast Cancer joint pain not to be believed and most recently the bottom of my feet have been so painful I can't walk. Weight gain, carb cravings, hot flashes (drenching type but they are not constant) brain fog, mild depression, drained of all energy- exhausted constantly, hair has changed (not thinner yet but more brittle?) high blood pressure for the 1st time in my life (meds now) and just generally feel yucky! I am just about done with feeling this way and may just tell the doctor that I can't handle it. Don't wish to try either of the other two and I can't take tamoxifen due to family history of clots/stroke. F 59 1.5 years
25mg 1X day
9/8/2014
 2  Breast cancer I was on Femora 4 years then found a lump in other breast had full mastectomy and reconstruction which is what should have happened the first time Femora did not prevent a recurrence side effects not good but a hundred times better than Aromasin where to start insomnia muscle aches bone pain cough red sore eyes stomach pain gas like I have never experienced head aches I am very active it's getting harder to get out of bed always tired I'm going back to my oncologist with some serious questions about this drug ??????? F 61 4 months
1
7/20/2014
 1  Stage 1 Invasive Breast Cancer Depression, extreme fatigue, mental fogginess, moodiness, constant extreme joint and muscle pain knees, hips, low back, plantar fasciitis, acne, muscle aches. Morning stiffness and after sitting for about an hour causes stabbing hip pain. This started after taking this for only 1 month with the first 2 weeks onset with everything from all the above to UTI and flu-like symptoms. I switched from Aromadex due to severe pain the very first week. Only strong RX pain meds work for this pain but then leaves me constipated and even more mentally dull. Doc wants to now try Femara. I don't want to get out of bed each morning and now feel like I'm in my 80s. F 57 2 months
25 1X day
7/13/2014
 3  Estrogen receptive breast cancer Frozen rt thumb, clicking of other finger joints in non dominant hand. Unable to make a fist first thing in the morning with some swelling. Some pain in toes-feels like hammer toes. Went off med for 3 weeks-no change. These symptoms didn't start until after being on med for 13 mos, now worried this will be permanent and could progress to other joints in other extremities. F 58 1.5 years
25mg 1X day
7/2/2014
 1  3c breast cancer Swelling and pain in joints. Fatigue. Chemo fog still present. Extreme Insomnia. Depression. Severe hot flashes. Throat and stomach problems. Unable to go back to work because of physical weakness and decision making process slow. Stopped taking it after 2 years. Have an appointment w/oncologist in 2 weeks to discuss. Oncologist stresses the importance of this drug, but can no longer live with the side effects. F 59 2 years
25 mg 1X day
6/15/2014
Email
 4  Stage IIB Invasive lobular, ESR pos I am experiencing hair loss, thinning of eyebrows and eyelashes. Intermittent headaches some near migraine. Days and nights mixed up. Some days just can't get motivated. Some joint pain primarily knees and neck. But 10000% better than Arimidex!!!! F 63 3 weeks
25 mg
6/1/2014
Email
 1  Stage 1 5mm Breast Cancer lump I had to give up Aromasin because it starting giving me severe, daily migraines. I went on to Arimedex. That one causes me severe insomnia. I have gained a total of 50 pounds on these drugs and I am entrenched in the eating disorder. I now have only 7 more months on these meds. F 53 3 years
25MG 1X day
4/9/2014
Email

Patient History
 5  stage 3 breast cancer weight gain/sleepless nights/mood swings/hot flushes/hair thinning the menopause all over again sadly but stick with it. Thankfully after 5 years still in remission and no cancer on mamo just had. Its not nice but stick with it. Now i have ceased for a week i am getting symptons still but they lessen each day. F 62 5 years
25mg 1X day
11/27/2013
Email
 1  Advanced Breast Cancer Fatigue, body and joint aches, mental fog, Flu-Like Syndrome. Felt like I was being poisoned and was 50 going on 95 years of age. Cancer was easier. F 52 15 months
25 mg 1X day
11/23/2013
Email
 1  Stage 1A/estrogen receptor positive Insomnia at first but that went away. After about 2 months, started becoming fatigued, deep ache in left shoulder and forearm, hands and feet have severe stiffness and joint tenderness, weakness in arms and hands, feels like flu without the fever/chills and nausea, muscle tenderness as if bruised in left hand and thigh, facial sweating (doesn't last long), and itching on scalp and body. It usually takes 3-4 hours after waking, in order to move normally and not be so fatigued. (I take meds in a.m.) Heat packs and Aleve and/or Acetaminophen seem to help but can't take everyday. I switched back to Tamoxifen after haven taken it for a year without any of side effects except for hot flashes and occasional insomnia. It's only been a little over a week but I still have the side effects from Aromasin. F 55 4 months
25 mg 1X day
11/20/2013
Email
 1  breast cancer Pain in joints/headache/sore throat/sex painful/extreme confusion/ Would rather risk death then to feel like I'm dying everyday. And the side effects don't go away in a week like promised! F 53 6 weeks
25 mg 1X day
8/12/2013
Email
 2  Breast Cancer Stage1A My Side Effects have been more constant of : Headaches, Mood Swings, Vaginal Dryness and Bleeding. Very Bad Insomnia , Nightly. Exercising has helped very much Walking Daily and Aerobic Exercising. At the beginning I was taking Terrible aside Effects , taken off and Started AROMASIN. Anxiety , Nervousness, Difficulty Concentration. Moods changes for No Reason. Crying over little things, Appetite seems to be up and down. Body Aches, Headaches for no reason. Blurred Vision sometimes. Joint Pain. F 53 3 months
25mg 1X day
6/11/2013
 3  bc/st 1/nonmet./6.1 cm/est. pos 3/11/13 -The hotflashes have improved somewhat. However, I am sick of the constant perspiring!! My skin is messed up (was always complimented on my skin looking so young before). Aged. Am on DHEA cream for vag. dryness. Seems to help. The headaches at night are maddening. I NEED SLEEP. I was only stage one with no metastases (spelled right?) Had total mastectomy with recon. I wonder if this is necessary. Dr. said contributing to osteopenia (precursor to osteoporis). AS OF 4/25, onc gave permission to go off!!! Said no proof after 5 years of hormone therapy that there is any further benefit. Said my prognosis is 99%plus because I did the hormone therapy. I went 7 years, so it is pretty certain. Onc said because I had chemo before surgery, had total mast., and have been clean for 7 years with the hormone therapy and because of the type of cancer it was, my prognosis is practically 100% without further aromasin or subs. Praise God!! Worth asking the questions!! F 55 0 days
25 mg 1X day
4/26/2013
Patient History

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