PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  acid reflux Extreme malaise after eating, along with headaches, thirst, and fatigue. I am pregnant, so at first I thought it might be gestational diabetes. I am getting off the Prilosec immediately. F 36 8 days
1/1/2010
 2  Horrible heartburn Over the years it became less effective and I started taking more to deal with horrible stomach pain. I developed arthritis in my ankle so bad I could not walk at night and as a long-time weight lifter, I noticed I was getting weaker at a rate not attributable to aging. Quitting was hell. Since quitting about two months ago the problems with arthritis have improved and finally I am regaining stregnth in the gym. Acid problems are horrible, but there is a reason the manufacturer recommends limiting this product to a few weeks use. For me, long term use was quite bad. Quitting was extremely difficult, but I seem to be slowly improving in the areas of pain and weakness. And now that I am off the medicine, I am learning which foods to avoid (pizza, beer, coffee) and my stomach is better than when I was on the medicine. For long term users, I highly recommend slowly reducing the dosage and then stopping (I tapered off over about 5 weeks). At first the stomach pain is horrible, but for me the long term health effects have been well worth it and I feel better off the med than on the med. Best of luck to all and thank you for your input. M 51 7 years
12/30/2009
 2  Acid reflux, heartburn Severe back and spine pain, low temp (96.5-97.5), tingling and numbness in toes and fingers (especially big toes and ring and pinkie fingers), heart stabbing pain (like a blood clot or heart attack), numbness in left arm, shooting pains, difficulty breathing and shortness of breath, difficulty swallowing, central nervous system failure like if i didn't breathe myself, my central nervous system wouldn't bother (went to the ER once in a panic), feeling like slipping into a coma then snapping out of it in a panic, chills, headache, dizziness, dry itchy eyes (like sand in them and no amount of eye drops helped), week heart beat, UTIs, and ringing in ears. Diagnosed Vitamin B-12 (B12) deficiency. Diagnosed 3x increase of TSH (thyroid stimulating hormone) to above normal levels (possible sub-clinical hypothyroid). A year ago I went to my doctor about numbness in my toes and fingers, and the doc thought it might be a vitamin B12 deficiency (a test proved so). He said to take a B complex vitamin (I take a daily Centrum). I mentioned my other symptoms, and he thought the chest pains were all related to my previous diagnoses of acid reflux. I've been taking Prilosec OTC regularly, and asked about the 14-day limit warning. He said don't worry, I need to take it forever. "OK". So over the last year my symptoms got worse, but not consistent. I could go days feeling OK, but other times very bad (I even went to the ER once). I've been back to see my doc and he never asked about or tested B12 again, or suggest Priolosec was to blame. I soon noticed a pattern when I stopped taking Priolosec regularly. I bet my B12 absorption has decreased even more and the daily multi was not enough to overcome the B12 issue, along with potassium absorption, etc. Yesterday I took a single B12 vitamin with 500 mg (8,333% DV compared to Centrum's 6mg 100% DV), and my body temp went back to normal, and I feel much better today. I wouldn't have tried that until I remembered the B12 thing a year ago. I am upset my doc did not make it clear that I need a high dose of B12 to overcome the absorption problems Prilosec causes, and that a daily multi-v wouldn't cut it, and not even suggest Prilosec was the cause, or even retest B12 (which is suggested on drugs.com for long term Prilosec users). M 38 2 years
12/29/2009
 5  GERD Nothing on brand name, but on equate generic omeprazole: weight gain, numbness/weakness in forearms, migraine-level headaches, eyes slow to refocus from reading to looking far away. I did a search for "numbness in forearms and eyes out of focus" and this site popped up in the google search. I've taken Prilosec since 2006 when I couldn't afford Nexium. Then I recently switched to the generic versions of omeprazole to save money. In August I got a horrid headache diagnosed as a migraine that came with forearm numbness/weakness, blurred vision, and a foggy head. That lasted two weeks. At some point (going to check my receipts) I got brand name prilosec again becasue it was on sale. Symptoms went away. Now on Equate omep. again and the symptoms are back. After reading these posts, I'm gonnna go off this for a few weeks and see what happens. Like another poster here I also had trouble mostly in my right eye. Just freaky! Never made the connection before reading this webpage! (BTW-it did cure my GERD) F 43 3 years
12/28/2009
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 5  GERD NONE I've taken Omeprazole for over 10 years and have never had a side-effect. And it totally relieves the heartburn. It's a wonder drug M 60 10 years
12/27/2009
 1  Burning Pain in Upper Stomach Dizziness,muffled hearing,racing heart,palpitations, shortness of breath,fatigue,feeling "out of my own body", my head feels like it has been stuffed with bunting,foggy headed, cold sweats, sweaty hands (my hands never feel like this!). Mood swings. Sever agitation/ anger,anxiety. My family is constantly telling me to calm down. I thought they were crazy! I took a two week cycle of the name brand Prilosec and felt okay. Then I bought the Equate Version and the symptoms started almost immediately. I had my doctor to blood tests because I thought I had some terrible disease. They came back normal. I ended up in the ER the next night and they did and EKG and blood work..all normal. They said it was GERD. Wrong! I knew it when they said it. I didn't take this junk this morning and I don't feel nausea but I'm cold and clammy and my hands are sweaty. I've also been a bit dizzy today. The dizziness and nausea have been horrible!! I'm assuming I'm going to have withdrawals from it. I was on a narcotic for chronic pain at one time and when I went of of the medication. I felt almost just like this. It's insane! I just hope it passes quickly. What are other people's experience with coming off of this stuff? I'd love to hear it. Were you clammy and sweaty and hot at the same time? F 34
12/26/2009
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 3  Acid Reflux It is day 3 for me on Prilosec. It sures works on the Acid Reflux. My stomach feels great......except I can hardly see. I have blurred vision, with vertigo, and a constant feeling of "HAZZY" if you can understand. I have read all of your comments...and this is very scary. Their is no side effects list in the box...WTF?? IT is working on the Acid Reflux.....but I stumbled onto this site by googling "Prilosec dizzy side effects" Hi ALL....welcome to the club. The side effects are very interesting. They are not debilitating, I was just unsure what was going on. Now I need to see if they get worse. I can live with this if it cures my Acid Reflux. My Doctor instructed me to take this for 2 weeks and then I probably will never have to take it again. This is what he said. He said that Prilosec allows your stomach to heal. So I have a few of the side effects.....but my side effects make me feel kind of out of it. This is day 3 for me......and I don't know what to do. I have read many of the horror stories here....and my side effects are mild compared to some......but I have them. Be careful, and monitor yourself. This is 100% Bullshit that they don't warn you inside the box about the possibilities of some weird shit happening. Good luck all. I marked this site. Awesome posts. I guess I am not crazy....LOL M 43 3 days
12/24/2009
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 1  heart burn/possible acid reflux I posted on 12/08/09 and forgot to list high BP 141/80 normally around 115/70 and ringing in my left ear. I have been off 40mg Omeprazole for 3 weeks now and the side effects have subsided but are still lingering to some degree. My chest pain is gone and my BP is down to 125/70. I still experience some weakness in arms and legs and have strange numbness/tingling sensation in the back of my head and neck.I also find that I am really fatigued at night. No more anxiety or stomach issues. I read that omeprazole can suppress acid production for 3-4 months after you stop taking it. i hope that the side effects don't last that long. M 37 20 days
12/23/2009
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 1  Possible GERD, H.Pylori ? Lump in throat, severe throat & mouth burning. Suddenly began having numbness, tingling in hands & fingers plus swelling, increased BP (always low before). Stopped 20 mg. dose following endoscopy & now increase in stomach acidity & discomfort since stopped pill. New gastric distress-increased symptoms. Had endoscopy that was negative.Never advised about side effects. Thought I had some very weird illness or virus. Did not relieve my symptoms now they are worse since stopping dose 5 days ago. Will this end? Any advice as to what to do to control withdrawal. How long does this last? F 63 16 days
12/21/2009
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 1   Chest pains, tingly arms, hands and feet, severe back, neck and left shoulder pain, weakness in arms and legs, wrists suddenly feel like I have carpal tunnel, chest tightness, heart palpitations, pale stool, anxiety, fatigue, near vision blurry but only in right eye, ringing in ears, occasional dry cough, high blood pressure 141/75. I had an anxiety attack at the end of October due to an extremely high amount of stress, but at least I knew the cause. Doctor prescribed Propranolol which definitely kept the anxiety at bay. Another side effect of the stress a couple of weeks later was acid reflux. Wound up going to the emergency room and they gave me Maalox with Lidocaine and Prilosec. About and hour I felt much better. I was prescribed Nexium but due to the cost, the pharmacist called the doctor and asked if I could simply take OTC Prilosec. Dosage 40 mg/day. About 3 days later I started to feel much better so I continued to take the Prilosec. After this I seemed to have so many symptoms, but attributed them to the stress. However at about day 8 of taking this drug, I started noticing blurry vision and my energy level plummeted, to the point where I would have to take a nap during the day or I’d fall asleep at inappropriate times of the day. This is highly unusual for me. Within the past 2 days, my muscles have started to ache horribly, especially my Pectoralis muscles and the chest pain is more frequent. (doctor says I don’t have a heart problem). Last night though, I just didn’t feel right so I took my blood pressure…HIGH! Of course that threw me right into a full blown anxiety attack and my blood pressure went up to 169/80. The only other drug I’m taking is Prilosec so I have to assume that it is the culprit for all of my symptom, not the stress which has actu F 54 13 days
12/12/2009
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 1  acid reflux severe anxiety, depression, loss of appetite, suicidal, stinging in the throat, out of my mind and world, very emotional, lack of sleep, dehydrated, metalic tongue, shortnesss of breath and tightness in my chest. This drug about killed me. I was taking the generic brand and thought it was helping. I never put it together what was going on with me until I found this site. I was ready to die. It didn't help my acid reflux, just made it worse. I have been off of the drug for 4 days and still are having some effects. I am not as depressed and the anxiety is starting to go away. Do not take this drug!! BADDDDDD!!!!!!! F 39 3 months
12/11/2009
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 2  nausea and vomitting extended time horrible chest pains and pain between shoulder blades, swollen face and fingers, lots of anxiety I just got on here to read up on prilosec and am going to stop taking it immediately F 36 7 days
12/10/2009
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 1  Gerd Severe anxiety, panic, tightness in chest, numbness in arms and legs. numbness in face left eye. Cloudiness unable to focus, feeling of being trapped in my head. feelings of despair and depression when I stopped taking it. All of which were not present prior to being perscribed a PPI. Was prescribed another PPI (Protonix) in April and over the next several months noticed increased tightness in my chest and difficulty maintaining composure (excessive outburst of anger/anxiety). In July ended up pulling over to the side of the road while driving home with what I now know were withdrawal symptoms from the first PPI (had run out a couple days prior). ER doc prescribed prilosec along with tranquilizers for panic/anxiety and I have been fighting what I thought was a neurological problem ever since. Got the flue a couple weeks ago and stopped taking prilosec because of the anti biotics and after a week of a nightmare of depression and anxiety I all of a sudden felt great (tired but great). Still hadn't made the connection so I started taking the prilosec again and was terribly ill by the next day. Only got two doses before it clicked and started to detox again. Worst withdrawal I have ever felt, thought I wasn't going to get through it at one point and now at day 7 off I am just able to get up and around. Be careful if you take any PPI's. Alternatives should be considered for gerd if you can do it. I am certainly going to explore some better options. M 37 6 months
12/9/2009
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 1  Acid reflux possible Ulcer Anxiety half hour after taking meds, severe chest pain, radiating into back, asked God not to take me yet, I was that sick and scared. My mood was detached, and could not communicate with others very well. Cold hands, sweats, had to lay with my head propped up and hands on stomach. Felt like crying allthe time. Could not move from this position. I did not have the syptoms until 3 weeks later, then Bam! I have been off for a day now and will be going in for a Ulcer Test Friday. I think the Docs don't check what is going on with these Meds. I am still waiting to feel like myself again. This is pure Poison! F 47
12/9/2009
 1  heart burn dizziness, light-headed, back, neck and left shoulder pain, weakness in biceps and legs, chest tightness, heart palpitations, abdominal pain, changes in stool, severe anxiety and fatigue I went the the ER one night with severe tightness/ burning in my chest. EKG-Chest X-ray, cardiac enzymes were normal. ER doctor prescribed 40 mg omeprazole and told me to try it for 30 days. After 3 days, I began to experience horrible side effects. I didn't think that prilosec could cause such severe symptoms and thought that I had some condition that was getting. worse. Several blood tests and CT scans later, my doctor could not figure out what was wrong and assured me that prilosec couln't be the cause. Thank God for this website! I stopped taking the omeprazole on Dec 1 and have been getting better ever since. I still and feeling the after effects but not as severe. I hope this stuff gets out of my system soon and that no permanent damage has been done. Please make sure that you ask to try the lowest dosage of prilosec first! 40 mg was overdosing in my case! M 37 20 days
12/8/2009
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 1  GERD/Reflux Burning/ tingling sensation in feet,even though cold to touch. Very short of breath, with dry cough. B/P shot up high. Anxiety and feeling depressed. Have had this shortness of breath & other symptoms on & off for several years. It was only when my B/P went sky high that I realised I could have a problem with Omeprazole. Looking back at my state of health when not taking this drug... I noticed a pattern had emerged, the breathlessness & cough had gone, I was feeling much happier & with more energy. The last time was in October of last year. Since then I have been back on this drug & have felt awful & progressively worse. I am no longer taking this drug, and would advise everyone to think twice before starting it. I have been off it for just a week now, The depression has lifted,, the anxiety also. I just hope the breathlessness will go soon .... it is quite debilitating. F 64 4 years
12/5/2009
 2  reflux I became so hungry nothing would satisfy me. I looked up increased hunger on the side effects but saw nothing, I am off it now, for two full days, and I am beginning to feel less hungry, hopefully in another week, I'll be back to myself. I was taking two doses a day. F 55 3 weeks
12/2/2009
 1  acid reflux severe diarrhea, intestinal distress, some nausea, back pain, some chest pain, weight loss, flatulence, belching. Pain around gall bladder area and under ribs, sore breastbone. I stopped taking this on day 10 out of 14. I am two days out and I am on the BRAT diet. I do not have diarrhea any longer but I'm also only eating bananas. Diarrhea and stomach pain (gas) ALL OVER has been the worst. Very shocked that there was no insert about side effects in box. Would not recommend. F 36 10 days
12/2/2009
 3  Gerd Shortness of breath, Chest pain, ringing in the ears. Started taking prilosec OTC 20mg once a day, after about 1 month I started getting shortness of breath, fatigue. Also noticed I have ringing in the ears as well. I have been off of the drug for almost 2days, hopefully shortness of breath will go away soon. M 46 30 days
11/30/2009
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 1  no appetite Took Prilosec for 18 months for having no appetite. I did not notice any difference ut continued on it. Finally was diagnosed with an 85% blockage in the right artery of my heart & had a stent put in. Continued the Prilosec, and still had no appetite, no energy,felt poisoned, and lost 26 pounds which put me at 96 pounds. I was hospitalized many times and felt better, but would come home and be unable to eat again. I am on Plavix and an RN told me about the recent news on the use of Plavix and Prilosec, so I went off of it and take Pepcid now. I figured out that whenever I was hospitalized, I was not given Pri;osec so I was able to eat and didn't feel "poisoned." I almost died from the use of this drug. It also affected my blood pressure (normally 110/60 and would go to 180 with a pulse over 100.) The last time I was taken off of in the hospital, I had a seizure and my pulse went down to 24. And of course, as usual, there was "nothing medically wrong with me." My F 67 600 days
11/30/2009

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