PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1   I feel totally sick. My heart rate increased and having hot flashes. This is just day 1. I hope this leaves my system fast. Throwing it away F 39 1 days
20mg 1X AN
4/1/2022
 1  LPR Waking up in the middle of the night with severe heart palpatations, shortness of breath, MAJOR ANXIETY, sense of dread. Prilosec made me suicidal. I thought I was going insane. My heart has been pounding nonstop. I would not have attributed this to Prilosec if I hadn't read this thread.. Stopping the medication immediately. I pray that this feeling goes away. F 25 3 days
20mg 1X day
3/10/2022
Email
 1  Gerds Ive created a facebook group for others who are going through this. Either you are experiencing nasty side effects or withdrawal from Omeprazole. Its call Proton Pump Inhibitor side effects and withdrawal. PLease join so we can help each other After a year and a half on omeprazole i developed severe anxiety and tremors. When i realized it was the drug i started tapering. Those side effects turned into withdrawal and it became worse M 50 1 years
30
1/29/2022
 1  Silent reflux High and severe anxiety, irrational fear, loss of appetite, nausea, shaking and jitters, throat tightness or lump in throat feeling, chest pains, severe panic attacks, racing heart, awaking from sleep with racing heart and anxiety, insomnia, hot flashes, cold shakes and sweats, lightheaded, feeling of doom or hopelessness, mood swings and extreme sadness. F 26 5 days
1X day
1/24/2022
Email
 1  Possible Dyspepsia I'm not sure I can be brief explaining the issues I've had since starting this drug. My experience was very similar to the person who rated this medication on 8/19/21. Although I wasn't on the medication as long as she was, the effects were nearly the same. The medication did help the initial problem but as soon as the second day I totally lost my appetite. I vividly remember prior to taking this medication, I was eating normally and my appetite was just fine. I had fullness and couldn't eat much. I had anxiety but it may not be related to this medication as I had other medical issues that were causing me anxiety. I had diarrhea, nausea after taking it in the morning, lower intestinal rumbling, and lost noticeable weight and still slowly losing after I quit taking four days ago. I just feel BAD, can't really explain it. All I know is, unless this is a coincidence with some other gastro problem, all my issues started after taking this medication. I see others have started out with a lower dose initially. I wonder why my PCP didn't start me off with a lower dose and increase if necessary. I'm scheduled for an endoscopy next week. I haven't been able to exercise (usual 3/4 times a week), hang out with my friends, I'm basically bedridden. I think it's time to revamp my diet. This medication is not for me. F 62 11 days
40 mg 1X day
1/14/2022
Email
 1  Acid reflux Just awful. Started with nausea and general lightheaded ness, then elevated to fatigue and joint and muscle pain. This is my first day not on it and I still feel icky. Don't take this drug. M 21 2 days
20 MG 1X day
12/26/2021
 1  Stomach Acid, GERD I have been extremely sick since taking. I got severe diarhea and was vomiting. My girlfriend said I looked like a ghost and as if I were about to pass out. Was exhausted and in a terrible mood. Made me feel as if I was dying. I am switching back to Nexium which is what I usually take as Nexium did not give me any negative effects amd worked for me. Do not take it, it is not worth it and so many people have had bad experiences. M 30 2 days
1/Daily 1X day
12/13/2021
 1  Acid Reflux Anxiety, Depression, Slight Vertigo, Hopelessness, Disassociation, Hot Flashes Started with 20mg then moved up to 40mg did not like how it made me feel physically so moved back down to 20mg a day for the last few months. I noticed the last two to three months my anxiety and depression began to rise. I would lay in bed feeling lost or disassociated from my friends and family and I couldn't figure out why. I also had a sense of fear of things which was super odd, I've never dealt with anything that made you feel so fearful and lost. The few days before I quit taking Prilosec I would cry for no reason at all and was frustrated as to why I couldn't figure out what was making feel this way. I finally decided to google Prilosec and anxiety and was blown away by what I found. Stopped taking immediately and have been off for a week now but still have episodes of anxiety and hopelessness. Hoping things get better soon! M 41 9 months
20-40 mg 1X day
10/11/2021
 1  GERD Dizziness, headache, depression, anxiety. Foggy feeling disoriented. Nerve pain in hands and feet. Severe anxiety when I try to fall asleep. Jumping out of my sleep with a racing heart. This medication should be taken off of the market ! I did not attribute some of my symptoms to the medicine while I was on it. When I got off of this medicine I experienced the WORST withdrawal symptoms. I felt like I was dying. I could barely sit up. I literally thought I was loosing my mind. Please aware of these possible side effects. F 29 6 months
40 MG 1X day
10/7/2021
 1  Horrible Severe anxiety pains in legs arms joints. Glad I read up about this M 39 0 days
40 7X day
9/30/2021
 1  Acid reflux Anxiety/depression, sadness, feeling of hopelessness about life in general! rapid heart rate, jitters, not at all myself. Stopped taking it four days ago when I realized it was causing these side effects, and I have started slowly getting back to normal each day. My doctor said it could take weeks. I highly recommend NOT taking this drug. F 60 16 days
40 mg 2X day
9/16/2021
 1  Possible ulcer Started having gas issues, and lack of appetite. Not sure what else as I look back, but withdrawal was hell for 2 1/2 months. I want to give hope to those of you who think you'll never feel good again, going through withdrawal. At different times I experienced heartburn, over fullness to where I couldn't eat much, severe anxiety for about a week, heart palpitations, high BP, headaches, diarrhea, absolutely no appetite, nausea, lower intestinal rumbling, gas, and couldn't sleep past 3:00 a.m. and lost 8lbs. Things got somewhat better, then 2 steps back. Finally at almost 3 months I've been able to eat(still don't like my usual foods quite yet) and sleeping is better. Still tired and trying to gain back my weight. Evil poison pill!!! I thought I was dying! F 62 2 months
20 MG 1X day
8/19/2021
Email
 1  Acid reflux Following a flare up I was recommended to double dose. I have never felt worse. Severe anxiety and feelings of doom. Constant worry that regular items I touch will harm me. Also blocked ears and ear pain. Been off it 2 weeks and still struggling. When will I get back to being my carefree self? M 41 100 days
20MG 1X day
8/17/2021
 1  Acid reflux Dizziness weakness tired felt like a zombie drunk like symptoms This medication does cure acid reflux but the side effects are no joke but the doctors even though they know the side effects they just turn a blind eye to it M 51 14 days
20mg 1X day
8/15/2021
 1  Barretts Esophagus The first 20 or so days seemed fine then it quickly went to very bad. It started in my left foot with a numbness/ burning sensation and quickly moved up my entire left leg and then started in my right foot. The slightest contact of anything on my skin felt like I was just shot with a hollow point. My legs became so weak I could hardly get myself up off the couch/ chair. I've been off of this poison for 7 days now and things are improving. I've been drinking at least 1 big bottle of powerade and also taking a gym supplement that has lots of the b vitamins and other minerals in it. Be very careful with this drug. Please do your homework on it before taking. M 53 30 days
40 MG 1X day
7/27/2021
Email
 1  GERD Night sweats. Increased sweating. Tachycardia (fast heart rate). Hot flashes. Clammy hands and feet. Bloated belly. Water weight gain. Increased urination. Extreme anxiety. Lump in throat. I've used omeprazole a little over a year. I stopped in June 6 of 2021. Today's date is July 24, 2021. I am still having side effects from it. It started with heart palpitations. I'm sensitive to heat. I feel hot a flushed all over even though I'm in a cool building. I've had my TSH checked and it's not menopause. I've been hospitalized for my heart. Currently on Bisoprolol for my heart. Some of the symptoms have gotten better. They have not cleared completely. I'll write another update in six weeks. I've read you see a difference at the 3 month mark. I hope so. Feeling hopeless. F 39 100 days
20mg 1X day
7/24/2021
Email
 1  LPR My review was posted on 7/11 as being highly satisfied. This is incorrect. I was extremely dissatisfied. I'm not sure how this happened except my fat fingers mistakenly choosing a (4). In no way was I satisfied with this product. F 47 14 days
20mg 2X day
7/12/2021
 4  LPR Dizziness, headache, fatigue, shoulder pain, high bp, anxiety, leg tremors, face spasms. With all the side effects you would think I had a stroke or a tumor. I honestly thought I was diabetic or had symptoms of ALS. I was very satisfied the first few days but by the 3rd day, I began having headaches. I didn't think anything of it until I checked my bp and it was very elevated. Other the course of the 14 day treatment, I experienced back pain, lightheaded, leg tremors during the night, anxiety when waking as if I didn't know where I was. I finished my 14 day regime and I am 6 weeks out but still suffering with many of the above mentioned side effects. Thankfully, my bp has returned to normal and no more back pain. I feel as if my life had spun out of control because every little tremor scares me. If you're prescribed this medication, please please talk to your physician before taking. F 47 14 days
20mg 2X day
7/11/2021
 1  Possible ulcer Started having a lot of intestinal rumbling and gas. Please don't take this drug! I'm so sorry I did! Withdrawal is horrible! So many issues that I Never had before I took it! Didn't realize the need to taper off this drug. Withdrawal has been horrendous. At varying times: heartburn, nausea, diarrhea, gas, intestinal rumbling, inability to sleep, jittery, hopelessness, headache, and The Worst, no appetite! Used to love chocolate! Lost weight to a scary point. Before this drug, all I had was occasional ulcer pain. 6 weeks off, things have gradually improved, but still struggling to gain weight and have an appetite, and feel normal again. F 62 2 months
20 MG 1X day
7/7/2021
Email
 5  Gerd None M 67 2 years
20mg 1X day
6/12/2021

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