PRILOSEC Reviews (OMEPRAZOLE)

Average Rating: 1.9 (1667 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

PRILOSEC  (OMEPRAZOLE):  Omeprazole is used to treat certain stomach and esophagus problems (such as acid reflux, ulcers). It works by decreasing the amount of acid your stomach makes. It relieves symptoms such as heartburn, difficulty swallowing, and persistent cough. This medication helps heal acid damage to the stomach and esophagus, helps prevent ulcers, and may help prevent cancer of the esophagus. Omeprazole belongs to a class of drugs known as proton pump inhibitors (PPIs).   FDA Approval Date: 1998-01-15 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PRILOSEC: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PRILOSECCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Possible stomach ulcer As time went on I experienced excess gas and stomach rumbling. It also didn't seem to help with pain. I stopped taking it and have experienced anxiety, inability to sleep well, general unwell feeling. Had heartburn for the first time ever, and the first day horrible stomach pain. Switched to Pepcid. Wish in had read through these comments before I started taking the drug. I would have avoided it. F 62 2 months
20 MG 1X day
5/31/2021
 1  Suspected GERD Severe anxiety, not being able to eat/swallow, joint pains, dizziness, nausea, headache. I was given this med because I had been having difficulty swallowing due to GERD. I took it the first day and I felt my throat closing/ear aches. Today I took the next dose and had the same symptoms. I haven't been able to eat and I've been feeling so weak. I was getting a little better with swallowing issues but I wanted something better. This medication made my symptoms worse to the point where drinking water feels so strained and if I try to eat anything, I feel pain in my ears. Did anyone feel like this??? Especially not being able to swallow or making it worse? F 26 2 days
20MG 2X day
5/9/2021
Email
 1  GERD/ heartburn Thought I was losing my mind. The most dark and deep soul-less, hopeless, despair filled week in my entire life. Crying uncontrollably various times each day. Considered multiple ER visits. Called hotlines because I thought I was losing it. Fearful of everything. Detached from my loved ones. Completely, utterly debilitating and horrifying side effects. Not to mention the most awful migraines, nausea, chest pain, stomach issues, body aches, etc. Eventually did some searching and found these posts and other sites. I stopped the drug immediately. It has been two days since I stopped. Still having panic/ anxiety attacks but not as long lasting, frequent or severe. Still having stomach issues and chest pain, body aches. Can finally eat somewhat normally again. DO. NOT. EVER. TAKE. F 37 5 days
20 mg 1X day
4/28/2021
 2  GERD First and foremost, I honestly do not take medication unless it is life or death. I believe in natural ways to stay healthy along with a good clean diet. But my GERD symptoms got so annoying, that I had decided to just give it a shot. It was only for 14 days so why not. I researched it and it seemed to be hopeful, plus if the side effects weren't pleasant, then I should be able to still push through for the full 14 days... I thought. So to start off, as for the heartburn and acid reflux getting taken away almost immediately on the first day, the side effects make this drug have you wishing you were off it and back to having heartburn again. Atleast you feel normal and can just pop a tum when things get bad. So, first day taking this, I had zero heartburn and felt normal directly one hour after taking it. I was very pleased. Has no side effects all day. Then on the second day the side effects hit pretty hard in terms of brain fog and anxiety, but I thought I'd just drink a ton of water and push through it to give this a shot, to see if my body adjusted. It actually did. The next 6 days I had almost zero sides besides a lack of appetite here and there and some nausea temporarily. Nothing too crazy. I figured that my body had adjusted to the medication and it was smooth sailing until Day 14. Then that all went out the window when Day 8 hit and it got 100x worse. Every side effect that you see that got reported on here, I ended up getting all in one day. I one small meal 45 min after taking it and felt so full that I felt like I was going to vomit and that feeling literally lasted like 8-10 hours. Even if I had hunger pains around then, I couldn't even look at food. Then ontop of that, the nausea was extreme. I then realized maybe it was time I had gotten off of it before my body became dependent, making it more difficult to stop. That's how bad this was. Day 8 was the day. Things get worse. Later that night, the extreme anxiety hit and the heart palpitations came with it right when it was time to fall asleep. Meanwhile I'm nauseous as hell and can't eat. So, I can feel myself falling asleep finally and then bam the anxiety mixed in with the heart racing, broke me right of of that rhythm multiple times. I couldn't even think straight due to how bad I was quietly panicking laying next to my fiancĂ© and I am not even close to an anxious person, so this was all new to me and I obviously knew right away that this had to be Prilosec's doing, So, what did I do? I had to unfortunately sit there all night drinking water and feeling this way like I was gonna die in sheer panic. Got zero sleep. I understood what it was and I had my only solution left. Quit taking it. So when I got up for work exhausted as ever, I took the pill pack and trashed it first thing. Now I am sitting here writing this review in hopes to st M 27 8 days
20mg 1X day
4/27/2021
Email
 1  heartburn High anxiety, heart palpitations, shortness of breath, fatigue, depression, mental fog, insomnia, disassociation, loss of appetite I had a bad reaction to Prilosec OTC. I took it in the mornings, before breakfast, for 7 days until I realized it is causing me issues. Starting around the 3rd day I began feeling more stressed and my heartrate was up to ~100 from 70, which is my normal resting heartrate. On the fourth day I had to drive for 2 hours and felt on the edge the whole time, pulse was 130. I recognized anxiety and set up a call with a psychiatrist to help me. I never had this before (or since). On the 7th day I realized that it might be the Prilosec, found others complaining and I stopped taking it immediately. The side effects took me around 2 months and a half to clear. The first 2-3 weeks were the worst, with many anxiety attacks and some depression. I also started waking up a lot at night, 7-10 times per night. The anxiety started to come and go, but took approx 8 weeks until I had the last attack. Insomnia took a bit longer to clear. I took vitamins (B complex, D), minerals (magnesium, calcium) and supplements (valerian root, pepsin HCl), pushed myself to exercise (run), but not really sure that these helped. Blood tests looked fine. My GP had another patient with same symptoms at the same time as me, but never heard of such effects before. There are recent studies that indicate a link (search for "Elevated anxiety, hypoactivity, memory deficits, decreases of brain serotonin and 5-HT-1A receptors expression in rats treated with omeprazole"), but unfortunately no actionable remedy/suggestion M 34 7 days
20 1X day
4/21/2021
 1  Gerd Terrible muscle spasms legs and hips I took this medication for years on and off at 20 mg and always suffered with muscle pain , I didn’t realize that it was the prilosec that gave me those pains until my doctor raised my dosage to 40 mg per day and the muscle pain and spasm got so bad I had to stop taking the medication F 73 2 weeks
40 mg
4/18/2021
 2  GERD At first I had no side effects. UNTIL day 5. I've just felt awful: rebound acid, chest pains, heart palpitations, waking up from sleep with my heart feeling like it's RACING. I believe medicine can do any kind of weird stuff and Prilosec has done it for me. I've taken Protonix and Prevacid with zero problems. Not sure why Prilosec is affecting me this way. M 24 8 days
20 MG 1X day
4/9/2021
 1  GERD Initially gave me bad heartburn. After day 10, it turned into panic attacks and insomnia. Being waken up out of my sleep. Feeling short of breath. The best way to get this med out of your system fast is to flush it out! Drink plenty of water! Like a gallon a day! Exercise to sweat and get more of it out of your system. Eat foods high in antioxidants to regain strength. Right now I am a day off of it and I feel hungover like I had a drink. But I dont even drink. But, please be encouraged. God will be with you. Please read Psalm 91. And stay away from this drug!!!!!! Not worth it! F 28 10 days
20mg 1X day
3/24/2021
 1  Silent reflux Panic attacks, depression, no libido, numbness and tingling, increased hunger, brain fog, tinnitus, gas, vertigo, dizziness, hip pain, back pain I've been off Prilosec since the end of December- most of the side effects thankfully wore off with the help of vitamins and probiotics. I had these terrible side effects linger for around 2-3 weeks when I stopped taking the medication. It seems like Prilosec gave me additional problems. I actually have heartburn now- before I just had silent reflux. Also, I'm constantly burping now, suspect this evil medication might have given me SIBO. My symptoms were actually worse after I stopped taking it- it must have still been in my system. If anyone has any advice, or wants to chat please email me. F 19 14 days
20 mg 1X day
3/23/2021
Email
 1  Heartburn High anxiety and depression. Brain fog and disassociation with reality. Muscle fatigue and shakiness I had no idea a ppi could make you feel this way. I hope since I only took it for a short while that these symptoms subside. I can’t work. I can barely eat. It’s awful. Please tell me this goes away. M 34 9 days
20mg 1X day
3/15/2021
Email
 1  Gastritis Was put on by hospital I have gastritis from a h pylori infection that's gone but left tummy inflamed was fed these had no idea etc until I felt off unwell Tryed to stop a few times but rebound acid hyper I got so triples the acid amount fir ages weeks months everyone is different so I'm stuck on it and it's making my tum so sore raw gnaw pain it's supposed to assist in healing so tum can heal not a cure Jyst to help acid do tum heals well for me it's 200% worse more burning more gnawing pain 24/7 went urgent care and the guy me straight back in it I now have ear hissing reflux thing blocked ears neck pain sore only one side though ear buzzing tones arm burns mainly one right side fuzzy neck pins needles effects on my hands swallowing difficulty awFull vile sensation on my face and neck so the rebound is similar to the side effects I did not have this only couple things prior to this Med and I feel the gastritis inflamation was to blame for a couple things but this is extreme and unbearable. I barely slept too Sickly to eat lost weight. I'm now trying to lower the dose even on 40 I am bad severe on 30 mg I'm the same no different I can't up the dose as I feel it's this ppi doing it and too scared to increase so today was 30 mg same effects 40 mg the gnaw started hour after taking I ate hour later the gnaw incr Do not use F 54 28 days
40mg 1X day
3/13/2021
Email
 1  Acid reflux Panic attacks, general anxiety, fear of dying, heart palpitations, tight esophagus, abdominal pain, mental fog, gas, buzzy feeling in abdomen and legs, muscle spasms, insomnia, psycho dreams, sharp pains under rib cage, feeling strong pulse in abdomen I had chest pains and was alarmed so I went to the ER. Was told it was just bad reflux. Followed up with a doctor and he recommend prilosec otc. 24 hrs after the first dose I had the first of many panic attacks. I sincerely though I was going to die for about a week. I was afraid to be alone with my kids because I didn't want them to see me die. On the 6th day, i could barely swallow and my throat was so tight. My logical brain finally realized something was going on and I started researching. The side effects are insidious. Finding others who shared this awful reaction helped me immensely. This drug is poison to many of us. I experienced all the symptoms I listed for a solid 4 weeks before it started to fade and I only took it for SIX days! I am now 6 weeks off this poison and still have occasional symptoms but thankfully they are weakening over time. M 48 6 days
20 mg 1X day
2/26/2021
 1  Silent reflux Hip pain, tingling in hands and feet, anxiety, depression, brain fog, racing thoughts, gas, stomach pain, increased hunger, vertigo, blurry vision, tinnitus, insomnia I've been off Prilosec since the end of December- most of the side effects thankfully wore off with the help of vitamins and probiotics. I had these terrible side effects linger for around 2-3 weeks when I stopped taking the medication. It seems like Prilosec gave me additional problems. I actually have heartburn now- before I just had silent reflux. Also, I'm constantly burping now, suspect this evil medication might have given me SIBO. My symptoms were actually worse after I stopped taking it- it must have still been in my system. If anyone has any advice, or wants to chat please email me. F 18 14 days
20mg 1X day
2/25/2021
Email
 1  Acid reflux F 45 5 days
20 mg 1X day
2/18/2021
 1  Acid Reflux. GERD Nausea - all the time. Chest pains, feeling dizzy, bloating, no appetite. Increased sweating. Tingling in fingers, lips. Sometimes pain in leg. I feel so ill all the time. The nausea is the worst thing. I don't want to look at food or prepare it let alone eat it. And yet I feel full and bloated. Also have tingling in arms and dull pain in left arm from time to time. Dull chest pain (I even went to get heart checked but it was OK). I tried to come off the medication slowly and finished on 28th January. How much longer will I have to feel ill? I would be grateful if anyone wants to email tips, how they are coping with the symptoms. How long did they go on for? Thanks F 64 5 days
20mg 2X day
2/17/2021
Email
 2  Gerd I have acid reflux and had been taking Prilosec once a day . My symptoms became worse so my doctor increases my dosage . I began having muscle pains in my legs and back . I suspected it was the Prilosec and stopped it . The muscle pains went away . I now only take Pepsid F 73 10 days
2/10/2021
 1  Gastritis/ h pylori Headaches, dizziness, vertigo, some stomach pain, back pain, some chest discomfort, some nausea, anxiety, heart palpitations I started feeling discomfort in my stomach area late August 2020. Got an endoscopy late September diagnosed with H pylori and gastritis. Started taking the medication for 10 days for the H pylori and I continued taking omeprazole on and off for the next few months. Took a total of about three months worth. I started feeling dizzy on and off during these months which I thought it was due to my stomach. I started having weird back discomfort late November which I thought was very weird, I thought there was something was going on with my lungs. Started feeling weird upper abdominal discomfort and chest discomfort shortly after my back stared bothering me which was also super weird along with the dizziness on and off. Beginning of January I started getting dizzy with headaches again, it continued for two weeks until I said enough and went to go see my regular doctor. He's the one that told me that I have slight vertigo and showed me that one of the side effects of omeprazole was headaches, dizziness and vertigo. Went cold turkey and I stopped taking that stupid pills immediately, fortunately I found this website the same day. I've been off this POISON for three weeks now!! the first two weeks of being off this POISON I felt horrible, major headaches, dizziness and just a lot of weird discomfort. All I could say is that after three weeks of being off I am feeling better, mild headaches on and off here and there, no real dizziness but definite M 40 3 months
40mg 1X day
2/9/2021
Email
 1  Gastritis/ h pylori Headaches, dizziness, vertigo, some stomach pain, back pain, some chest discomfort, some nausea, anxiety, heart palpitations I started feeling discomfort in my stomach area late August 2020. Got an endoscopy late September diagnosed with H pylori and gastritis. Started taking the medication for 10 days for the H pylori and I continued taking omeprazole on and off for the next few months. Took a total of about three months worth. I started feeling dizzy on and off during these months which I thought it was due to my stomach. I started having weird back discomfort late November which I thought was very weird, I thought there was something was going on with my lungs. Started feeling weird upper abdominal discomfort and chest discomfort shortly after my back stared bothering me which was also super weird along with the dizziness on and off. Beginning of January I started getting dizzy with headaches again, it continued for two weeks until I said enough and went to go see my regular doctor. He's the one that told me that I have slight vertigo and showed me that one of the side effects of omeprazole was headaches, dizziness and vertigo. Went cold turkey and I stopped taking that stupid pills immediately, fortunately I found this website the same day. I've been off this POISON for three weeks now!! the first two weeks of being off this POISON I felt horrible, major headaches, dizziness and just a lot of weird discomfort. All I could say is that after three weeks of being off I am feeling better, mild headaches on and off here and there, no real dizziness but definite M 40 3 months
40mg 1X day
2/9/2021
Email
 1  GERD High anxiety, lightheaded, heart palpitation, random chest/body pains, headaches, cold hands/feet, tremors, brain fogs Took for a week and everything went fine. On the 8th day, heart palpitations kicked in. Anxiety left me awake until I'm exhausted enough to sleep. Been off it for 3 days now. First day I haven't been super lightheaded. I cleaned up my diet to lessen the acidity and it's slowly working. Please stay away from this awful drug. M 27 11 days
20MG 1X day
2/4/2021
 1  Acid Reflux First day after taking the medicine, I woke up with flu like symptoms (muscle aches and extreme fatigue). Got worse the second day after taking the second dose. Started feeling better a few days later but the acid reflux came back. Took one pill and by the end of the day I had Muscle weakness, tingling, pins and needles all over my body. If anyone has any advise pls email me. F 25 3 days
20mg 1X day
1/4/2021
Email

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