GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  PCOS Severe nausea, occasional diarhea, dizziness/headache, and drowsiness. I began glucophage 16 days ago and immediately began feeling the side effects. I thought that maybe it was all in my head, but after reading this forum I realized that it wasn't. I could handle the headache and other things, but the nausea was the worst thing I have ever gone through. I dealt with it for a week and called the doctor to see if I could do anything different. I am only on 500 mg a day (which is a small amount compared to many others on here) and he did not want to lower my dosage but suggested that I try taking it at a different time during the day. I was taking it with my evening meal (around 6:00p.m. or so) I would feel fine all evening but when I got up in the morning I was deathly ill. He suggested that I take it a little earlier and maybe the nausea would hit while I was sleeping rather than in the morning. So, I adjusted the time that I took it over a few days and it was AMAZING how different I felt. Ever since I changed my dosage time I have felt like a new F 29 16 days
8/10/2008
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 4  PCOS Slight queasy feeling if taken with too little food. Just wanted to give a one month update. The diarrhea has ended and taking the pill is much easier now. I've lost 5 lbs, mostly because I just eat less throughout the day. Most importantly, I got my period back after 8 months without! So far, pretty happy with the results. Will update again later. F 25 30 days
7/3/2008
 4  PCOS Taking 850mg twice a day. Brief but FIERCE nausea and diarrhea. I frequently went from feeling just fine to wanting to lie in bed or over the toilet and just cry. After two days, it became much better, but I am still having nausea/diarrhea if I overeat or eat too much fat. This page has helped me so much that I just had to leave a comment. I hope to add updates as time goes one. I've had PCOS since I was 13, and have taken Metformin since then. However, because I'm stubborn or just don't like to admit I have a condition, I always stop after a few years. Well, this time I stopped and gained 40 pounds, so now I'm back for another round. So far, so good. Some horrible nausea and diarrhea, but my appetite is back under control and I've lost weight already. Plus I have more energy to get through the day. F 25 7 days
6/10/2008
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 4  PCOS Diarrhea in the first 2 weeks, then started body pain and general weakness I have started taking enough water, Gatorade, Centrum multi-vitamin and Nutricap and I am just feeling much better. With the component they have, the hair loss is getting better and the body pain is gone. I guess it was because of vitamin B12, B6; D and calcium. Anyways, I recommend everyone a complimentary nutrient intake. By this way you can minimize METFORMIN side effects. F 28 30 days
8/22/2008
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 4  Type 2 Diabetes I had no side effects at first. However I have been on this for one year now and am starting to have bad bloating, gas, and nausea. I have lost 40 pounds and all blood tests coming back are really good now. F 33 1 years
6/18/2008
 4  Insulin Resistance + suspected PCOS Until I switched after 3 months from regular to TIME RELEASE, I had very bad stomach pains, fatigue, and general weakness unless I was ridiculously careful about eating (like a bite of fruit every 10 minutes). Once I was on the time release, I then experienced the same symptoms from time to time along with what I eventually associated as hunger. I've been on it 10 years and I'm thinking about getting off. My hair follicles have become finer and less dense, though only noticeable to me. I have trouble keeping weight off without the pills, but on days I forget to take them, I feel like a million bucks. I'm sure it's the best RX for me and my condition, but I want to try treating it without the medicine as I think my liver and kidneys are paying for it. I just don't feel right. F 24 10 years
6/23/2008
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 4  PCOS w/IR I presently feel really good. I have only experienced 2 negative side effects- 1 being gas that is more prevelant approx. and up to 9 hours after taking. I fill a little bloated but nothing that is effecting my clothing. 2nd would be becoming extremely hungry if I don't eat something around every 2 hours. The further away I get from taking the pill the less prevelant it is, which I assume is because the meds are working out of the body. On a happy note this is day 4 and show a 5 pd weight loss already. I am overall pleased with my bodies response to 500 mg once a day. My dose will go up after 7 days then again after 14 days. I only have one concern and that is how quickly the weight is coming off. I have noticed a lack of desire to eat sugary or starchy foods. I don't have a problem eating meals I am just making healhy choices when I do. I did loose weight from 2002-2004 (60 pds) but it was the hardest thing I have ever done in my life. I worked hard labor and exercised a minimum of 1 hour a night with a 1200 cal strick diet. I am now praticing 1500-1700 cals a day low fat healthy carbs little to no sugar. I haven't started exercising yet and will add slowly so I don't overwhelm myself. F 31 4 days
2/27/2009
 4  PCOS QUESTION: I have taken two of these pills, yesterday at three and this morning at eight and I don't have side effects yet. Can any of you tell me when you first started having the SE's? Thanks! QUESTION: I have taken two of these pills, yesterday at three and this morning at eight and I don't have side effects yet. Can any of you tell me when you first started having the SE's? Thanks! F 27 2 days
3/12/2009
 4  PCOS I experienced stomach aches when initially taking it and still do occassionally if I don't eat enough food before taking it. It seems to help if I eat half of my meal, take the medicine, and then eat the rest. I started taking Metformin at the beginning on January to help with my PCOS. I am taking 1000mg twice a day. I still haven't had a period and was wondering how long it takes to regulate? I have taken pregnancy tests and they are negative. Any suggestions? F 27 1 months
2/4/2009
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 4  insolin resistence nosia, headache for the first week only. Great medicine, helped me loose weight as well F 31 40 days
5/2/2008
 4  PCOS A little bit of loss of apitite and I am drinking more water than I used to (but I drink a lot of water already) This is my second time starting this medicine. The first time was a year ago and it was the extended release version. I quit after 1 month because of the stomach cramping. After my sister who also has PCOS got pregnant using it I decided to give it another try. This time around I am on the non extended release at 500mg 2x a day. When I went on it the first I had done a lot of research before ever taking it so I knew what kind of side effects the medicine has. With both times starting out I also took it along with and anti-diarrhea pill. This combination keep me from the dreaded diarrhea side effect. This second time around my doctor gave me and anti-nausea pill to take the first two weeks until I get used to the medicine. The combination of the three medicines has keep me side effect free. F 33 7 days
2/20/2009
 4  Type 2 Diabetes Explosive diarrhea 15 minutes after taking-Was on 1000mg 2x day but now better with lower dose of Metformin XR. Have lost 26 pds.Bloodd sugars are normal. F 54 3 years
1/26/2009
 4  Possible PCOS, Insulin resistance Stomach upset (with sugar), flatulence, some nausea, and loose stools (depending on the amout of sugar I've ingested). This is a great medication as long as I control the amout of sugar I take in. I've been on it since August '08, however taking it consistantly since the end of Novemver. I've lost 15lbs since November. I've noticed I'm not quite as hungry. i take 2 500mg twice daily. F 25 6 months
1/23/2009
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 4  Diabetes Type II, PCOS I instantly felt very lethargic and needed over 12 hours of sleep. In the first week, I had body ache all over, slight diaarhea if I ate fried foods, Feeling queasy all the time, & bloating. The good side : it drastically improved my sugar level from 300 down to 99-108, under a week of being on the medicine. Weight went down 2kg under 2 weeks, with no excercise at all. Recommended! F 37 12 days
12/3/2008
 4  type 2 diabetes First three weeks had horrible cramping, gi problems, headaches, overall nausea....dosage was increased gradually, but it didn't really help. Felt horrible for those three weeks. Has definitely helped with blood sugar levels.....if you can make it through the initial side effects F 35 4 months
4/7/2008
 4  PCOS, insulin resistance At first - Hunger, nausea and dizziness if I didn't get enough cals or at the right time. Stopped after a month, tried balancing progesterone and thyroid. Once they were in balance, I still couldn't lose weight. Now at 500 - 1000 a day, for the last three weeks, I have lost 14 pounds. After only gaining for the last 8 years, I am VERY HAPPY. I now have more energy and plan to ease into more excercise. I am glad I gave it another chance. I do feel more energetic- even a little wired at times. After having been nearly comatose at the end of a workday, this is a blessing. F 35 25 days
4/9/2008
 4  Type II diabetes For the first time on this page I could compare my experiences with those of other patients. I was a bit nauseous in the beginning, but that passed. What does bother me is that the intestinal effects are unpredictable and range from diarrhea to constipation -- and don't take a magnesium supplement at night with your pill!! Oh boy ... you're off to the bathroom 3, 4 times from about 3am. Explosive. Not nice at all. I also seem to tire far too quickly and I am often sleepy -- side-effects? It would seem so after reading other comments here! I take 1000 mg twice a day, with meals. I put myself on a high-protein diet and I certainly don't do low-fat anything. My diet is a bit of a problem during the day -- one gets an awful desire for carbs. But my A1C test after 3 months was 5.4%. (It was 6.8% when diagnosed) It does work. But I also take AntaGolin (a South African product, not medicine, helps with insulin levels) as well as cinnamon capsules. I am, however, VERY WORRIED about the hair loss complaints. I have the impression I'm losing too much hair and wondered why. My hair is baby soft and thin -- can't afford to lose hair! I'd like to cut down on the Glucophage but I don't want to mess up my blood glucose. I've lost 10 kg (about 22 lbs) in less than 3 months and although I'm pleased with that, I can hardly afford to lose more. Yet I don't have much of an appetite. I should add that I do drink wine with dinner, and my pills get swallowed with wine!! Wine seems to help my numbers. F 66 2 months
3/25/2008
 4  insulin resistance/infertility some diarrhea in fist week, some stomache cramping,loss of appetite no weight loss but no weight problem I've been taking this medication since 10/06 for about 2 months but I stopped taking it after the first two months due to the side effects I started taking it again at the end of 4/07 and I found out I was pgnt today but I don't know how safe it is to continue taking it now that I'm pregnant since I miscarried in 6/06 and I've read that it is better to be off while pgnt does anyone know any different F 42 21 days
5/31/2007
 4  PCOS Diarrhea, gas, extreme tiredness, nausea It has slowed hair growth on my face somewhat, and the side effects have gotten better. I take 500mg. 2X daily. Never take a dose too close together, because I had a horrible spell of nausea and throwing up. F 26 4 months
6/5/2007
 4  PCOS Very Mild Nausea, decrease in appetite, no diarrhea, but I'm definately "regular" now Hoping to see improvement with irregular menstral cycles and weight loss. F 28 2 weeks
4/11/2007

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