GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  PCOS/Insulin Resistance diarreah,excessive gas, nausea the first few weeks I am feeling a lot more energetic,not really sure what else i have gained as of yet. I am on 1500 mg a day and am hoping in the next few weeks I'll see more results. F 27 3.5 weeks
3/12/2005
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 3  Insulin resistance Diarhoea and nausea first 2 weeks. Now severe constipation and abdominal bloating. Takes 3 x 500mg per day. Reduced sugar cravings. No weight loss so far. F 40 1 months
4/1/2005
 3  regulate my periods/ get pregnant nausea, extreme tired all the time, fatigue, headache, diarrhea, cramping, backache, loss of appietite, dizziness My doctor put me on 500 mg of metrofin for the first two weeks, then uped it to 1000 mg a day a week ago. called her today because having extreme tiredness and dizzy all day so she put me on 750 mg on time release to help with the symptoms. hoping to get pregnant soon, my periods are already regulated. F 23 3 weeks
5/7/2007
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 3  PCOS The bloating is unbearable! I haven't had abdominal bloating like this since I was 6months pregnant. Any help or suggestions out there? Love to hear them. Decreased appetite, no weight loss-frustrated! Taking 1000mg/day I am hopeful that this will reduced the cysts and return me to a "normal" cycle. it's somewhat comforting to have a name for what my body has been going thru for the past few years, and nice to know that I am not alone. Been taking meds for 1 month F 35 1 months
4/20/2006
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 3  PCOS-related insulin resistance Stomach cramps, diarrhea, thinning hair and hair loss similar to male-pattern balding. Taking Metformin (500 mg x 2) helps ovulate monthly and keeps blood levels under 120... however, a decision needs to be made... period or wig? Searching for a solution that may help with the hair loss. F 41 270 days
2/26/2008
 3  PCOS / Insulin Resistance Severe stomach pain, cramps, diarreha. Went on and off the drug because of this side effects. I would wake up in the middle of the night with a sharp stomach wrenching pain and had to get up and run to the bathroom. It became impossible when I had a job that limited bathroom breaks. It did regulate my menses but I had to stop taking it on behalf of my stomach. Now I'm off glucophage and seem to always have heartburn, occasional acid reflux and often soft/watery stools. F 28 3 months
4/27/2005
 3  Impaired Glucose Tolerance nausea, bloating Haven't seen any improvements really. Thought after reading some of the posts that I might see some weight loss - nothing yet. Have 30 lbs to lose. Any suggestions? I exercise 4-5 days per week, and eat approx 1200 cal. a day. F 34 12 days
3/7/2007
 3  Metabolic Syndrome Headache, explosive, urgent diarhea after eating. Just kind of felt badly all day. Burning feeling in back of throat. Was taking 1000 dose of metformin xr in morning with breakfast, but will switch that to dinner time as some other posters have recommended. Also may adjust back dosage and "build up" as others have suggested. I had a high fasting glucose, high cholesterol, high b/p and significant abdominal weight gain over 5 year period. Also have had infertility issues for years but no one ever mentioned PCOS, but I can look at the symptoms and recognize myself. Am hoping for the weight loss, and would hope that in turn helps the cholesterol, hbp and other metabolic syndrome symptoms. Read the comments from other women to try taking in the middle of the evening meal to avoid the whole day of nausea. F 44 1 weeks
4/21/2007
 3  PCOS nausea, extremely tired all the time, headache, diarrhea, cramping,loss of appietite, dizziness, flu like symptoms I don't know if my period is regular yet. first week I lost 3pounds and it came back the next week. I don't feel seek no more. I wanted to lose 15lbs. My weight at this moment is 115. I am 4'11" so I could still lose some weight. I am reading that people are losing so much weight in just a few weeks and mine is not going down at all. Is it because I am not overweight? F 28 3 weeks
5/20/2007
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 3  PCOS nausea, extremely tired all the time, headache, diarrhea, cramping,loss of appietite, dizziness, flu like symptoms I don't know if my period is regular yet. first week I lost 3pounds and it came back the next week. I don't feel seek no more. I wanted to lose 15lbs. My weight at this moment is 115. I am 4'11" so I could still lose some weight. I am reading that people are losing so much weight in just a few weeks and mine is not going down at all. Is it because I am not overweight? F 28 3 weeks
5/20/2007
 3  acne, weight gain, hair growth I had some minor stomach upset that went away after a few days and I would get an occasional mild headache. The acne has cleared up a little and the weight seems to be going away. I haven't noticed a big difference with the hair growth yet. F 30 1 months
5/10/2007
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 3  Type II diabetes explosive watery diarrhea many times a day I have taken this drug for 2 years, although when it was titrated to 500 mgs 2x a day (AM and PM), I get diarrhea about 2-3 hours after taking it in the morning and have about 3-6 bouts of diarrhea the rest of the day. And then I get it in the AM once I get up, about 1x. A lot of times I don't take it in the morning if I have somewhere to go that afternoon and can't readily get to a bathroom. I have, however, lost 20 lbs, and am still losing. My doc said she would change the med, but I like the weight loss and will hang in there as long as I can. As for the diabetes, I am not very compliant, but my A1-C has been relatively near normal. F 56 2 years
8/7/2007
 3  PCOS muscle and joint ache, metallic taste,SEVERE constipation, bloating and gas, weight loss and no cravings 1st week muscle and joint ache, metallic taste 2nd week SEVERE constipation, bloating and gas.Lost 5 lbs in 2 weeks no cravings no appetite F 48 2 weeks
9/25/2007
 3  Insulin Resistance Morning hunger pangs, diarhhea, lately noticed extreme weakness in legs and arms. I took 500mg a day for one week, then 500mg twice a day for about two weeks when I noticed the extreme weakness. I think I have lost some weight maybe 10 lbs. I have a lot of weight to loose. My sugar and insulin levels were within normal range just slight increase from last year, low carb diet for 2 to 3 years and no weight loss. I think the weakness will pass. I hope this is the problem and can be resolved before my health suffers more extremes. F 43 23 days
5/22/2007
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 3  type 2 diabetes Gas, bloating, burping and thinning hair It has helped with my numbers somewhat but not without having to endure some side effects. I am really curious about the hair loss. I realize there are other things that can cause this but I'm reading that there are other people on glucophage that are also complaining of hair loss. My doctor said it is not listed as a side effect. Would love to know if it really does cause this! F 50 3 years
1/29/2008
 3  misdiagnosis of PCOS Nausea, loss of appetite, dierriah for weeks, loss of libido, very painful stomach cramps, blood in stools. It helped me ovulate each month, but I had to stop it because of the blood in the stools. As it turns out I didn't even have PCOS and was later diagnosed with endometriosis. F 29 3 months
1/30/2008
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 3  diabetes Some cramping and loose stools the 1st and 2nd day. Then I felt fine. I got sick the following week and vomited so the doctor discontinued the meds. F 37 7 days
1/9/2008
 3  PCOS , Diabetes Type II Extreme thirst , stomach cramps , metallic taste. Alternating bouts of constipation and diarrhea. Sometimes so horrible either way I feel as if I'm literally dying. Headaches and tiredness. My glucose levels have been running pretty normal. Most times around 90-160 depending on if I am fasting or after I have eaten etc. Since being put on Metformin 5oo mgs 2x daily. I have had reoccuring bouts of painful constipation and extreme diarrhea. Extreme diarrhea meaning 6-8 times in a day. Of the "explosive" form at times. Most times leaving my rectum feeling as if someone has yanked my intestines out through it.. Yikes ! A lot of inconveniences , as I have to stay near a bathroom at all times. I have watched what I have eaten , and it doesn't really seem to matter most times. I know my husband was on it and he had the diarrhea frequently as well. BUT when he had those episodes his sugar levels were higher. Like around 200 and up. Mine I can have the diarrhea and my level is only 100. So it is unpredictable at best. F 36 41 days
1/15/2008
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 3  PCOS/Infertility/Reccurrent Misc. Cramping, nausea, vomiting, diarea, I am highly suspiscious that it will work. I have PCOS but am not overweight, excercise regularly and eat a low GI diet. Nonetheless, after multiple miscarriages - I am willing to try anything, so am on this and Clomid and then Progesterone when we get pregnant. Good luck to us all. F 34 4 days
7/16/2007
 3  PCOS/ Trying to conceive Diarrhea,Headaches,Mild Fatigue When I became pregnant with my son 4 years ago, it happened quickly.This time it's taking alot longer. I was diagnosed with PCOS in June when I decided to visit the doctor after not having a period since March 27th.An ultrasound done on my ovaries confirmed that it was PCOS. I have obviously had this along time because a "normal" period for me would come every 8-10 weeks ( when I wasn't on the pill).My girlfriend who also has PCOS told me about Glucophage so when I seen my doctor, I was well informed.She said she was pregnant in 6 weeks. Since taking this, I've had some diarrhea, headaches and a little fatigue. Within the last week, my breast are sore and I my fatigue has increased.....fingers crossed! I'm hoping to get pregnant soon with my 2nd and last child. If anyone has any feedback with success or advice, I welcome it! F 34 6 weeks
7/17/2007

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