GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  doctor M 67 8 years
1/13/2007
 2  Diabetes II During first month extreme stomach pains and nausea on empty stomach. I felt like I had to eat more in order to avoid the stomach pains. It has lowered the increase in sugars from overnight fat burning. (6'2 M 24 3 months
4/2/2004
 2  Type 2 Diabetes General discomfort; aching in every joint, nausea, diarhhea & constipation. Causes more problems than it solves. Cinnamon & Chromium Picolinate work better and are safer. Upped to twice daily 1 week before symptoms began. M 57 2 months
5/13/2006
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 2  Type II Diabetes and elevated BS Did fairly well without problems when on 500 mgm twice a day, however my BS stayed high so my Endocrinologist increased it to 1000 twice a day. This caused stomach distress, diarrhea and nausea. As I am also on HIV meds I took a vacation from both but now have definately associated the symptoms with the increase in Glucophage. I will cut back to 500 and see if that improves things after speaking with the MD. That said, I am not sure that the benefits outweigh the side effects at this point as I am keeping the folks who make Pepto-Bismol in business M 64 5 months
1000 2X day
2/27/2010
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 2  Type 2 Diabetes Diahirea Bad w/ea tablet / Same w/ 1/2 tablet. Have to stoptaking after 2 or 3 days. Then start again. I don't Recomend-it. Had taken before with same results M 71 3 months
10/29/2001
 2  Insulin Resistance Nausea, stomach cramps, bad headaches, fatigue, drowsiness, pain in upper right quadrant, generally felt unwell Have tried to take Metformin (850mg 2 times per day) 3 times for about 3 weeks each time over the past 8 months, because I read very good things about it for Insulin Resistance. Each time I tried to take this medication, I would have unbearable side effects, which just seemed to worsen, instead of lessen with time. I even tried cutting the tablets in quarters, and just taking a quarter of an 850mg. tablet 2 times per day, but still could'nt tolerate it. I really wish it would have worked for me, because I know that I need it. M 35 8 months
4/8/2005
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 2  insulin dependent diabetis Started Glucophage last Nov. Caused gastic upset as the dose was increased to 1000 twice daily. Cut back to 1500 daily. By Dec began to have periods of extreme weakness. I also have heart desease so went back to Cardioligast and family doc. They found nothing abnormal in tests and blood work. Extreme weakness continued. Returned to diabitis dr. who didn't think glucophage was a problem. Started eliminating other drugs in a trial and error method. Still could hardly get out of bed. Talked with 2 different pharmacist who said glucophage could be the problem. Stopped glucophage 3 weeks ago - doing insulin coverage for elevated blood sugars. Change in activity has been amazing - not ready to run a race yet but can play with my grandchildren again. Seeing endo dr. on Tues. Will ask for a change in meds. This is the only reason I can see for extreme changes Will not take again M 61 10 months
8/23/2008
 2  PCOS Explosive Diarrhea and nausea. So far having extreme hunger as well. I was on this off and a few years ago for over a year. 2 different doctor's put me on it. It made me so sick and miserable, especially each time they increased my dosage, that I quit taking it for the past few years. I also never lost any weight on it. My OBGYN put me on it yesterday, so I could give it another try. I have been losing my hair since I was 15 and have always had trouble with my weight. I was able to lose 40 lbs off of the meds and kept it off for over 2 years, but have gained almost all of it back in a very short amount of time... despite training for half marathon during this time. I took it for the first time again last night and was up from 3am until 7am with massive cramping and diarrhea. I am starting out just 1 500mg tab a day and then add each week. I hope I don't have to go through this for a long time again. It's unbearable for any length of time. Most of the posts I've read said that they lost hair, but all of my endocrinologists said it would help me get some M 29 1 days
11/20/2008
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 2  Type 2 Extremely tender and inflamed joints, also muscle pain At 750 mil/day, it was enough to drop my sugar from 124 to 103, however, the side effects were unacceptable. Although others claim a weight loss, I actually gained 15 pounds in the four months that I was using it. I could have lived with this, but the joint pain in my knees and hips was so severe that it even hurt when I was trying to lay in bed at night and I could no longer exercise in the morning. I dropped the dose to 250 mil/day and most side effects have disappeared with sugar now at about 115. This is about as close as I can compromise. M 56 4 months
1/12/2009
 2  Diabetes type 2 General 'not well' feeling, abdominal pains, intense hunger, nasty bowel movements I take 500 mg twice daily. It has lowered my blood sugar about 40 or so points, but the side effects are quite bothersome. I suspect my Doctor will want to increase it the next time I see her and am anticipating that the side effects will be even worse. Thay have not decreased since I began taking it. M 52 2 months
1/13/2010
 1  Sugar Explosive diarrhea and or vomiting with NO warning. Often happened in public. I got off it. It got to the point that I was No longer able to leave my house for fear I would get sick and embarrassed. M 59 3 years
30
6/24/2015
 1  weightloss due to lypodystrophy constant, explosive diarrhea I have left more pairs of dirty underwear in bathrooms than walmart sells in a month. Chronic diarrhea, explosive and uncontrolable. Constantly looking for the nearest toliet. M 38 1 years
9/21/2009
 1  Type 2 Very sick. Throwing up, Naseua bad cramps, continued diarrhea bad M 55 3 weeks
6/10/2009
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 1  Type 2 Diabetes Diarreah, joint pain, nausea, weakness, weight gain, peripheral edema, blood disorders, High triglycerides, kidney and liver problems. I took it for a year and 1/2 and now all my health is messed up. I've got organ damage because of Metformin, Januvia and Glucotrol. Please, check always about allergic reactions to medications before taking them so you don't end up like me. Now I am allergic to all Diabetes Oral medications. Good Luck! You may email me if you need further info. M 40 1.5 years
7/28/2009
 1  Type 2 diabetes Diarrhea. Don't believe anyone who tells you that you might experience episodes of diarrhea which will go away as "your body adjusts" to this drug. In my case, it was the opposite -- no problems at first but gradually over a period of many months I started experiencing episodes of diarrhea. Eventually it became almost a continuous ocurrence -- I had to always be aware of where the bathroom was everywhere I went. It got so bad that I even ended up taking Immodium as a precautionary measure every time I got on a plane or took a long car trip. I began to wonder if I had Chron's disease or IBS. Never related it to the Metformin since I hadn't had problems to begin with. Then I saw a gastroenterologist who suggested I try stopping Metformin. Within 48 hours I was totally cured! And have been normal ever since. This is a horrible drug. M 60 2 years
4/1/2009
 1  Type 2 diabetes explosive uncontrollable diahreea Only used it for two days. If this is what I have to deal with to control my just-diagnosed diabetes, I'd rather go blind and have my foot amputated. M 48 2 days
5/28/2007
 1  diabetes same as others listed With the comments on this side. The person eating card board: I suggest you ask your doctor for Humalog insulin, injected every two hours you can again eat a normal meal. I once could not eat a sub sandwich without glucose of 400 afterwards. I now eat sub sandwiches with no problem. I am not over weight, I lift weights five days and am hitting 660 pounds on the leg lifts. Doctors and drug companies will continue to convince you to continue with this drug. Don't believe a word. I have achieved great success by usuing Humalog. But you have to work at it. My approach is a hassle, but you (with discipline) will lead a healthier life, eat normally and within 30 days, (of tossing the drug) I felt so much better. Again, this drug should have killed me, but I lived by the Grace of God. Not by my doctor's action, not by a drug company's action, but by mine. I research daily on the diabetic condition. Few will listen to a word I say. I am not a doctor, I have no clout and my word is worthles to M 56 10 years
3/31/2007
 1  diabetes I should be dead from using this, but I tossed it and use only Humalog insulin 11 shots per day. If you have kidney problems, read the warnings. The warning says it is not for you or me. My anemia cured after stopping this drug use. Vomiting, gas, cramps and anemia came. Also lactic acidosis I think likely was happening. Again, I should be dead, but I am one of the lucky ones. Did my doctor take me off Glucophage no. I did It sucks and never should have been approved. A programmed approach of humalog injectings every two hours will make you very healthy and give you normal glucose counts. This drug is a huge money maker for manufactuers, and a loss of health and life to the consumers M 56 10 years
3/31/2007
 1  Type II diabetes Very bad - explosive - diarrhea and all the discomfort that goes with that. Dehydration as a result. Initial dosage was 2 x 500mg per day. Very angry that the doctor didn't mention the potential side effect. Information on the drug is confusing - it's considered very safe and widely prescribed, yet has bad side effects and is very hard on the liver and kidneys. M 51 4 days
12/26/2007
 1  diabetes belly aches....head aches....lethargic....drugged after effect...fog/brained took glucophage 500mg with glucotrol(10mg) M 59 3 days
6/8/2001
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