GLUCOPHAGE Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (586 Ratings)

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 Type: Rx Drug

  

GLUCOPHAGE  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 1995-03-03 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  insulin resistent/possible PCOS Prior to diagnosis I had diarrhea, now the diarrhea is less extreme. I am truely not hungry. I have lost 8 lbs in the first week and half. I hope I feel this so positive a year from now! F 38 18 days
1/4/2002
 4  type 2 diabetes unpredictable bowel movements F 43 6 days
1/19/2004
 4  diabetes 2 I took the generic metformin made by the Teva company. It gave me Bells Palsy. I'd black out. Felt foggy. Stopped taking it and palsy cleared. Doctor told me I was wrong. Went back on it (1000 mg a day) and Palsy returned. Took actual med and no palsy but muscle pain,especially midriff and left side. No weight loss. Doctor told me I was wrong and ordered me back on the metform. Palsy returned. Take the actal med now and no palsy. Do have muscle pain, especially midriff and left side. No weight loss. Don't take it if I have to go in public because of diarhea. F 58 1 years
9/22/2004
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 4  insulin resistant dry mouth, sick feeling, gas, decrease in hunger(thanks), no diarrhea(?) hand on scales are slowly dropping!!!!!!!!! F 51 1 months
7/12/2002
 4  early stage of diabetes Slight headache and nausea, frequest bowl movements, slight stomach cramp. Thankful I found this forum, because I was concerned about the symptoms I was experiencing and comforted by the fact they seem to be very common. F 66 2 days
500 1X day
3/12/2011
 4  PCOS/insulin resistance Diarrhea alternating with slight constipation, cramps, stomach gurgling, headaches, bursts of energy I was on this med about 5 years ago. Had similar side effects, except for these weird bursts of energy! It definitely helps with weight loss (the first time I was on it, I lost about 45 lbs along with diet and moderate exercise), which in turn will help lower my chances of diabetes. And that's pretty awesome because I HATE needles. It's worth some of the discomfort to me. F 25 1.5 years
up to 1500 1X day
3/20/2011
 4  PCOS Diarrhea, nausea, vomiting, bloating, sleepiness, headaches. I experienced terrible diarrhea, nausea, vomiting from this drug, however, if you give it the chance, stick with it for a few weeks, and get through the side effects, they subside, and the results are- for me- ovulation and weight loss. This is very important because not only are my chances of pregnancy increased greatly, but my chances for diabetes and gestational diabetes are decreased because of the weight loss. I suggest it- but you must be patient with the drug. These are KNOWN side effects. If you must, increase more slowly. For me- it was worth it just to increase more quickly because every increase gave me more side effects, so better to feel terrible for 2-3 weeks and be done with it. Than to feel terrible for a week and a half three times for each increase. I suppose it depends on what you are willing to deal with.... F 25 6 months
500mg 2X day
4/7/2011
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 4  PCOS The 1st week I was taking 1 tablet in the evening before bed. I felt dreadful. Tired, dazed, bloated. I didn't have too many stomach issues though. Just felt like I had flu symptoms. Then I upped the dose by 1 more pill in the afternoon and had no side effects. After 1.5 weeks of taking the medication, I felt back to normal. I am taking this medication for infertility. I'm very slim so had no idea I might be insulin intolerant, anyhow, after 2 months all my cysts have disappeared and I'm therefore hoping I'll fall pregnant soon. F 31 2 months
500 2X day
1/26/2011
 4  PCOS Occasional cramping and diarrhea, mostly after eating fatty foods. Decrease in appetite. A few episodes of mild heartburn. I was very nervous to start this drug because of all the side effects I had read about. I'm terrified of vomiting (emetophobic) so the fear of side effects was quite strong. Overall, though, it's not too bad, and I'm relieved. The cramping and diarrhea can be inconvenient, and there have been a couple of times that I've stayed home or come home early to be in my own bathroom. One great thing is that I find that I'm not craving chocolate anymore, and don't really feel like snacking. My advice? Don't be scared by others' side effects, and give it a try. F 32 16 days
250mg 2X day
12/22/2010
 4  PCOS slight nausea at times and some diarrhea (once a week at most), 5-10 lbs weight loss I have been taking metformin for 6 months now to try to treat PCOS as my first attempt at treating infertility. Although this medication did not help regulate my cycle, I don't mind being on it. I feel as though it has regulated my blood sugar, I have lost a few pounds without trying (always good, right?) and the side effects have been fairly sporadic and minimal. If only it had worked to treat my PCOS! F 33 6 months
500 MG 3X day
10/22/2010
 4  PCOS + Diabetess type 2 occasional loose stool, tiredness, headache (bad) Yesterday my sugar level was 125 in the evening (past reading 235+)- YAYYYY!!! It definitely takes time to work. With diet you can control diarrhea/constipation. I have really bad headaches on the top of my head :-( Any ideas what to avoid or help with that? I will start writing down what I eat because not every day is bad... Hoping for a baby next year! F 31 8 days
500 2X day
9/21/2010
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 4  Insulin Resistant/Weight Loss Constipation, gas, bloating, upset stomach, loose stools I started this medication slowly with 500mg for 1 month then moved to 1000mg for 2 months. During this time I have experience slight appetite decrease and actually had some constipation. With my follow up Dr appt she has increased my dosage from 1000mg to 2000mg. I have only been taking this for 2 days now but have experienced looser stools but only in the morning so it doesn't affect my daily routines. F 34 3 months
2000 mg 1X day
9/29/2010
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 4  PCOS Gurgling stomach, loose digestion, fatigue, and decreased appetite. It is a relief to have a medicine that helps fertility that does not make you gain weight! I have been on metformin leading into assisted conception and first trimester of a successful pregnancy. I am back on now for pcos hoping for another successful pregnancy. I am happy to take the bad with the good that comes from this medicine. F 40 7 months
850mg 2X day
9/28/2010
 4  infertility started out one a day for a week, 2 a day for a week etc, now I take 500 twice daily. I had NO side effects at all until the fourth week. I take methyldopha and hydrochlorot for high BP. I now have severe nausea at night and the dreaded flatulence is appearing. I really do think the hydrochlorot is playing a part in the nausea as I had nothing for a whole month until I started taking the BP stuff. No wieght loss as yet, but again a side effect of the BP meds is wieght gain so maybe its even stevens. My appetite has diminished greatly and I also have really achy arms and legs. I am hoping to get pregnant so will stay on the meds until told otherwise, just hope the nausea and dizziness goes away. F 38 35 days
500 2X day
6/4/2010
 4  PCOS upset stomach at first, definate lack of appetite, a little tired sometimes Started at 500 MG twice a day with no changes, so doctor changed my dosage to 1000 MG twice a day. I have had great results. My periods are still not normal, but they are a lot better than before. I lost 15 lbs the first 3 months I was on the new dose. I just don't have much of an appetite. Sometimes the idea of eating is enough to make me sick to my stomach. I've been eating better and exercising and have now lost 61 lbs all together. I am hoping the medicine will help me begin ovulating so my husband and I can conceive. F 36 1 years
1000 2X day
7/7/2010
 4  Type 2 Diabetes There's your normal, every day flatulence, and then there's toxic, OMG, evacuate-the-premises, decomposing landfill, nose-hair burning, worse than rotting carcasses at low tide near the New Jersey Turnpike flatulence. With one small dose of Glucophage, you could make the brave, fearless workers at your local sewage treatment plant wrinkle their noses in utter disgust. It works, but have an evacuation plan in place and a gas mask handy for yourself and each member of your family. F 35 1 months
500 mg 2X day
5/19/2010
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 4  insulin resistance The first night I took the metformin I had terrible cramping and diarrhea. I was pleasantly surprised that the second night I felt fine. Every morning when I wake up I have to use the bathroom right away because of mild diarrhea, but no cramping or pain. It doesn't interfere with my life because it only happens first thing in the morning. I feel good, and have lost 10 lbs in the three weeks I've been on it. F 33 3 weeks
1500 MG 1X day
5/5/2010
 4  Insulin resistance The drug has caused some nausea, but nothing that's a real problem. I feel somewhat calmer. I don't know if that's the drug's side effect or something unrelated. I have not weighed myself but I feel I've lost a couple of pounds already, and that's important because I can't seem to lose and maintain weight loss due to hypothyroidism. I'm better able to resist donuts - a big problem with me. I still have no energy, but hope that will change. F 51 2 weeks
500 2X day
4/15/2010
 4  PCOS When I took 2 500mg tablets per day, I had constant anxiety -- that feeling in the pit of your stomach when something bad is about to happen. Not a listed side effect, but absolutely linked to Metformin for me. Mild stomach upset when I first started taking it, but none now. I dropped down to 1 tablet/day and the anxiety went away. F 34 8 months
500 1X day
2/17/2010
 4  PCOS/IR/Weight Loss diarrhea 1st night only. dull headache some days. More energy, 10lbs lost so far. Will get numbers checked again in 2 weeks. F 30 2 weeks
500mg 1X day
3/17/2010
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