LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  panic attacks really no side effects in the 1 st week, im un the middle of my 2nd week, some itching although its winter and i get dry anyway. A little gassy, and bloated to the point i feel like i gained 10 pounds Buspar for me was the best without any side affects, but Lamictal is better than Prozac, but i am loosing my hope with anxiety medications. I am still nervous, very nervous, and hope i get better soon. F 43 12 days
2X day
12/30/2020
 3  Bipolar 1 Tingling in back of throat, restlessness, a bit hyper, insomnia first few days after that I slept but woke often, vivid dreams (good ones), yawning, tingling in eyeballs. The side effects were minimal. Didn't like the hyper feeling. Got a lot of work done though. Felt less depressed right away! F 58 12 days
100mg 1X day
8/25/2011
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 3  Bipolar I itchy arm pits, mild skin discoloration on my fore arm (not sure if either of these are from the medicine) I've taken 50mg for 12 days. I don't really notice anything different. I'm apprehensive about this medicine because I'm depressed, lethargic, have no energy and my Dr. would not prescribe antidepressants for me. : ( So I'm hoping that this will help with depression first. F 30 12 days
7/6/2007
 2  MIxed state bipolar disorder One week into taking the 25mg starting doseage, I began to feel as though I had a cold, then it progressed to more flu-like symptoms with a migraine that lasted for about 5 days. 3 days after starting to feel ill, I got a rash that started on my thighs and then began to spread to my lower legs, back and arms. I became feverish. I called my psych and she sent me to a dermatologist (conveniently it was her husband). He biopsied a piece of tissue from my thigh and called several days later to tell me it was a reaction to the medicine (Stevens Johnson). I stopped taking the meds the day I went to the dermatologist. I cannot say that this medicine worked, but also cannot say it did not work. Since I'm allergic to the medicine I guess I'll never know since I had only been taking it for 2 weeks when I had to cease taking it. Lucky me - the 1 out of 3000 it's prescribed to that has a reaction. I was so hoping that this would be the "magic pill". My family physician tested my thyroid just the other day to rule out hormonal problems and said he could prescribe seroquel, but I'm terrified of taking that, putting on weight and feeling tired all the time. F 31 12 days
6/4/2007
 1  bi-polar rash within a week and now has covered my whole body F 57 12 days
10/13/2007
 1  Epilepsy I experienced night sweats, insomnia, deep depression, sore throat, and my body was starting to feel like I was hit by a mac truck, then I started to get an awful red rash all over my body. I stop taking the meds that day, I started to feel better in less than 24 hours. Within 48 hours my rash was gone, my throat felt better as well as my body. And it did nothing to control my seizures. F 34 12 days
2/23/2007
 1  Partial Seizures Burning in my hands, arms, back...rash. Too bad - I thought it was going to be a great drug. All the doctors said it had few side effects and was kind of a mood stabilizer. Pay close attention to the burning sensations and rash. M 45 12 days
7/3/2009
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 4  Bipolar 2/Agitated Depression trouble speaking (finding the right words), rapid heart beat - I think this is due to the drug. Has anyone else experienced this? Please email me at [email protected] I really like it so far. I have suffered from depression and anxiety for years and nothing has really worked. My doctor finally decided that it might be worth giving this drug a try. I started it almost 2 weeks ago and am currently on 75mg. F 26 11 days
9/7/2006
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 3  Bipolar 1 Irritability!!!! Im an all around nice person, but this medication has made me miss. pissy pants! I also have had some paranoia, and really HIGH highs. I told my Dr. right away, and he said that its called hypo mania. Well I have been diagnosed with bipolar 1 for almost 12 years, and let me tell ya, I have never had a manic episode like that before. I am going to give it a chance, because honestly that the only way you can truly rule out a medication...speaking for myself. F 24 11 days
50mg 1X day
2/15/2011
 3  major depression w/ mood swings At first I had increased depression, suicidal thoughts, anxiety attacks, panicky feelings, extreme irritability and insomnia. After about 9 days, just insomnia and some irritability. I am diagnosed with major depression with psychotic features. I recently developed major mood swings within my depression (no mania). I am only taking 25mg and will begin to take 50mg in 3 days. Initial side effects were pretty bad and I felt severe depression, constant anxiety attacks, irritability and insomnia. After about 9 days on this med, I have begun to feel a bit better with only some irritability but I still have the insomnia. I wake up 3-4 times a night, wide awake and unable to sleep for some time. I also take Effexor XR, Abilify and Librium. All these side effects are new and from the Lamictal since I have been on the other meds for some time now. F 31 11 days
5/29/2009
 3  Bi-Polar and Depression Runny Nose (Rhinitis), slight sore throat, itchy skin, cough, knife stabbing headache, trouble concentrating and finding the right word, increased irritability, sleeping 10 - 12 hours, groggy in the morning I did find, as one of the readers said, that the longer I took it, the more used to it I got. I was willing to give it a bit longer but my pdoc said if I had this many side effects after 2 weeks, we should try something else. It made it hard for me to concentrate when reading, I couldn't think of the right word, I was spacier. I didn't like that at all. It also made me sleep too much (I already do) so I took it at night. F 54 11 days
12/11/2009
 3  Bipolar oversleeping one night/not sleeping the next, feeling lethargic all the time, weight gain, never hungry This is the second time I have been on Lamictal, the first time (I was on it for 2 months) my dosage was taken up to 100mg and I cannot remember the exact side effects but I did have a toenail that fell off for no reason, now reading people's reactions, perhaps it was the medication. I was sleeping all the time and in general just "bored." I am becoming very easily frustrated with finding a medication that will work! My doctor says to be patient, and we will build up to 400MG. F 23 11 days
1/23/2008
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 2  Bipolar II Violent rash. Flu symptoms. I took 25 mg a day for a week and everything was fine. 4 days after I increased to 50mg, I developped a very severe rash. It looked like a bad sunburn, on the upper body at first and spreaded to the whole body gradually. Turned purple sometimes. Very itchy. Too bad because I got the sense this medication works very well. F 35 11 days
9/24/2006
 1  Bipolar II Sensitive stomach, severe depression, crying, inability to inarticulate, very hard to get up in the morning, urge to sleep all day for hours. I am still furious about what I went thru with this drug. Furious. I have been on SSRI's for 12 years and what Lamictal made me feel was how depressed I was before being on SSRI's. It's been 5 days now since I've been off Lamictal and I'm still trying to get back to normal. I finally have my normal, hopeful, optimistic mood back but I haven't been able to articulate as well which is frustrating. I began a job 3 days ago but couldn't cope with it because of withdrawing from this horrible medication. I feel like a guinea pig with this. Like they just throw meds at people after meeting them twice. Then when I finally had presence of mind to call Dr's office, his horrible assistant chastised and criticized me for going off the drug at all. And for not calling them about it on a Saturday night. That's a whole other issue, her abusiveness. So I'm still on my Lexapro which I've had great luck with. My Dr. still thinks I'm bipolar II so I'm sure they'll try to give me something else soon and I F 42 11 days
6/1/2007
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 5  Mood swings Soar throat. I have only been taking this drug for 10 days. I broke out in hives a few days ago but figured out it was due to switching laundry detergents. I have to say the first day I took it I noticed a huge shift. I wondered if it was just in my head but I am still totally level headed, my paranoid obsessive thoughts are gone. I feel like myself completely just calm and at peace. I have been reading for days researching this medication. I know everyone is very different but I have to say I am terrified (in a calm way lol) about potential health risks. My mental state has never been debilitating. I am highly functional and extremely driven. But I am very sensitive and if I am under stress or unable to sleep well, work out, and or keep a perfect diet... I begin to be reactive and emotional to the point of confusion. I haven't always been this way but get like this sometimes. On this drug I don't want to drink because it makes me feel sick. This is not a bad thing at all, it seems as I get older I just don't handle drinking as well as I used to. I really want to just stay at this dose but I was supposed to dose up a couple days ago. I am meeting with my doctor in a few days to further discuss the risks. The scary thing about this drug is it can really mess up your liver, kidneys, brain...At least people have had these experiences and that scared me. I am a single mom with no support from anyone, a college student, a home owner with a huge mortgage, the list goes on. I can't afford to hav F 33 10 days
25ml 1X day
2/12/2011
 5  Treatment Resistant Depression Headache daily, dizziness and a little nausea the first few days. Even though I am on a small dosage, I can honestly feel it working already. I have treatment resistant depression and I am taking this along with Lexapro and Wellbutrin. My doc is upping me to 50mg per day next week. Already I am feeling more awake, alive, motivated, clear thinking, and less hopeless and sad. I have had the munchies pretty bad, sort of like PMS cravings, but I hope those go away in time. It's not bad enough to make me want to stop taking it. A few people have told me I seem "better" since I started on Lamictal. I hope it's everything I was looking for and I can get on with my life finally. F 33 10 days
25 1X day
7/20/2010
 4  bipolar II mixed mild nausea, some confusion just upped dose to 50 mg and have experienced fairly rapid results with calming negative racing thoughts...am taking with 90mg cymbalta (doc's idea)... was taking cymbalta alone but descended into an anxious depressive state with much agitation...so far minimal side effects with grateful improvement...also use 100mg seroquel for sleep...will continue to update in two weeks M 50 10 days
12/9/2005
 4  MOOD DISORDER (Bi-Polar 2) Absolutely crazy and vivid, often disturbing dreams. GI problems (mostly flatulence). I just started taking Lamictal recently and noticed an improvement in my mood in 3 days. Also after the 3rd day is when my disturbing and vivid dreams started. The jury is still out on this med for me but I am willing to continue. I have run the gamut on mind altering substances from Prescribed to illegal drugs (which I know didnt help and made me worse, especially ecstacy/MDMA). Ecstacy was fun but I now know how much that stuff messes with your brain chemistry and potentially causing brain damage. I wonder how many people young and old who participate in illegal drugs are causing their own demise into depression, anxiety, bi-polar mood disorders and the like. So far so good with Lamictal though (fingers crossed). M 38 10 days
10/19/2005
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 4  Anxiety, OCD, and BPD Vivid, disturbing dreams and nightmares, increase in acne, weight loss I really liked Lamictal. It helped with my severe anxiety and panic attacks and obsessive thoughts, and agitation. I'm not sure if it was the placebo effect because it was only a week in and it was such a small dose, but I definitely noticed an improvement. I had to stop it only 10 days in because I noticed it was making my acne worse. It wasn't anywhere as bad as Lithium, but it was still enough to make me feel more insecure. Another side effect was the vivid dreams. I was having extremely vivid, detailed, disturbing nightmares every night. I also experienced weight loss and lack of appetite but this wasn't a dealbreaker for me. The acne and nightmares were however. I really wish I could've kept taking it. F 20 10 days
25 mg 1X day
3/30/2020
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 3  ADHD/Depression/Bipolar extreme fatigue,night eating but not hungry during the day,sedated,moments of intense irritability, but i get over it real quick and i am able to reflect and wonder why the hell i got so irritated at that person. I have been on lamictal for 1 week, I just quit a week ago ater gaining 25lbs on Lithium. I am not sure if some of these side effects are from Lithium withdrawal? any ideas? F 32 10 days
8/6/2007
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