LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  bipolar Headaches, dizziness, aches all over, drowsiness, blurry eyes when reading I did better on 75mg as opposed to the 100mg I take now. I tried 125mg but couldn't stand the headaches, dizziness, and the "flat" feelings. On the mood charting I do I seemed to be either 0 or -1 ALL the time. F 44 2 months
10/15/2005
 3  Bipolar II "Foggy" brain, grogginess, trouble finding right words, difficulty typing, difficulty reading, acne, difficulty sleeping. I feel extremely agitated and ANGRY, although I'm not sure if this is due to the drug. I had to stop Zoloft, which I was taking along with Lamictal, because my doctor thought it was inducing hypomania. However, the hypomania has continued even though I have been off of the Zoloft for 2 weeks. I feel very productive and talkative in the morning but it turns into agitation and extreme irritability in the evening. F 29 2 months
6/2/2006
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 3  Bipolar Taking 150mg now at night. Getting up to 200mg in the outcome they want. I'm extremely tired and can't get anything done. Extremely fatigued and want to not even go out of house. I sleep 12 hours through night and still tired mid morning? F 37 2 months
150mg
12/8/2014
Email
 3  Severe depression/possible bipolar Started taking 25mg of Lamictal mid-April, working my way up to 100mg per night. Now, after almost a month of taking 100mg per night, I am having night sweats and extremely vivid dreams (not necessarily nightmares). I was prescribed Seroquel to help me sleep, so I just assumed that these side effects were a result of the Seroquel; however, now that I read all of the postings of similar Lamictal side effects...I'm led to believe it's the Lamictal. Also, I have recently experienced more acne (in locations I've never had it before) and itchy/dry scalp. I was on Lithium prior to the Lamictal, which I HATED due to all of the negative side effects. The Lithium blurred my vision and caused forgetfulness and difficulties with short-term memory. The blurred vision has continued with the Lamictal, though my forgetfulness has improved. I have not noticed any coordination problems or any lack of creativity. As this is marketed as a "mood stabilizer," though, I have to say that I h I am giving this medication a 3 because I still feel as though I may be adjusting to it; however, I have been on it for two months now, and I truly do not feel as though it's done anything positive for me. I still feel as hopeless and as overall depressed as I did prior to taking Lamictal. F 32 2 months
6/27/2008
 3  bipolar depression i had previously posted how wonderful this drug is at 25 mg. when i moved to 50 the muscle aches came. I thought I was sick, even went to my family Doc. Found info that leads me to believe it's the lamictal. My psych said he has never heard of this side effect, I'm begining to wonder if I need a new psychiatrist. It was wonderful at first at helping my depression but I couldn't stand the aches and headaches. As soon as I stopped, they went away. Psych asked me to go back on 25 mg, so we'll see how that goes. F 33 2 months
10/29/2007
 3  epilepsy Hair loss, vivid dreams Not too many side effects so far. It has been an ok drug. The main one I am concerned with is hair loss which seems to be getting worse. I also have more dreams, and vivid ones. M 25 2 months
11/10/2008
 3  seizure I had my first(and only so far) tonic clonic seizure in June - started w/ Keppra & Dilantin. Dilantin made me so dizzy, I walked like I was tipsy. So, switched to Lamictal (now taking 100mgs/day) about 2 months ago. Mostly I feel well other than dry mouth and recently extreme nausea - feels like the first trimester of pregnancy (but @ 56 I now that is not the case). Overall I feel better with the Lamictal than I did w/ other medications. After reading some of the other blogs here, my problems seem insignificant. One of my major issues is to think that I have to be on this drug for the rest of my life because of ONE seizure. But I am afraid to stop. I would not want to have a seizure while driving, and thank God I didn't the first time. But having to stop driving for 6 months has made such a total change in my lifestyle. Just to be able to get back to that is enough to make me continue w/ this med. F 56 2 months
11/17/2008
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 3  bipolar depression none really that I could tell I can't say anything truly bad about this, but I can't say anything good. It really didn't do anything to help me. Moods still weren't stable after taking some 2 months. F 30 2 months
4/7/2008
 3  Bipolar mood swings Large amount of weight gain in a small amount of time. Felt very tired. Messed up my blood sugar. Weird dreams. Trouble sleeping. Swollen limbs. Tender breasts (also went up a cup size) Weird medicine! It's a shame, because both me and my family noticed a huge difference on only 100mg of lamictal. I wasn't easily angered, I was calm and happy go lucky... Positive, and my manics were under control. BUT I also gained 30lbs in 2 months!!! With no change in diet... My blood sugar was always wack and had me feeling horrible. I always felt tired and lethargic but yet had trouble sleeping. I thought I was having a pregnancy scare but noticed that tender (larger breasts) were a side effect... I believe this drug also had me retain water and be swollen! It could work if you don't have horrible side effects... F 26 2 months
100mg
9/4/2015
 2  Chronic anxiety bipolar This med sucks. I already had loss of appetite and it made it worse. Loss of hair. This has not helped with my anxiety at all. In fact it made it worse. So bad i have a hard time leaving the house. Dr just put me on Brintellix because the anxiety was making me depressed. F 53 2 months
200 mg
10/18/2015
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 2  Bipolar 2 , anxiety, depression Extreme fatigue, sleepiness, increased anxiety, afraid to leave the house. Missed work a lot. Upper abdominal pain constantly, nausea, hip pain, acid reflux. I was taking it in the morning with food. I don't want to give up on this med. Abilify made me gain 40lbs so I will not go back to that. I want to stick it out for at least another month. I'm hoping that if I start taking it at night time before bed then the side effects won't be so bad. F 49 2 months
50mg
4/5/2015
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 2  Mood Swings Nausea, Increased depression, loss of short-term memory, mental fog, loss of appetite, clinching jaw, felt "dumbed down", crying jags, irritability, INCREASED ANXIETY! Started taking 12.5 mg as I am sensitive to all medications. Lifted depression in 24 hrs. (no exaggeration) but caused anxiety. Tried going up to 25mg and felt extreme irritability, off the chart anxiety, mild lower neck pain, sore throat, stuffy nose. Went back down to 12.5 and I still had bad short-term memory loss, then I started feeling really down, isolating and a little paranoid. I didn't want to leave home. Made depression worse. I just felt out of it. I wish it would have worked for me, but as I said I am highly sensitive to all medications. I hope this posts can help someone. F 55 2 months
12.5 mg 1X day
9/29/2017
 2  Currently At first, I felt worse, then I felt better, and now I feel worse again. I am super agitated, I get anxious again, I run my mouth and I cannot stop sometimes, I feel angry a lot, and I get so hyper to the point of crying because I literally cannot calm down. It is like it helps the constant mood swings in a way, but it also makes them worse. I have developed intrusive thoughts as well, which I have had before..but not this bad. I do not cry anymore and my depression is gone, and so are my other mood swings, but I get mad so easily now and I get super hyper to the point of feeling sick. I have not been able to get ahold of my doctor. I am wondering if I should taper myself off until I can get ahold of her. I am only on 25 MG once a day, and I was told that 25 MG is not even that high of a dose. So, I am not too sure what to do now. I do not like how I have been feeling lately. It works and then it does not. I do not get it nor understand it. F 27 2 months
25 MG 1X day
8/10/2020
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 2  Acute Depression/PMS I am so greatful for all your posts! I have been having a lot of the same side effects. I feel no motivation, tired all the time, loss of any personality, just really "Blah". As others have stated, it did seem to work at first. Now i am up to 100mg and i am starting to feel like i am going backwards in my treatment. I am also on 150mg of Zoloft. We have tried several anti-depressents that seem to work at for awhile and then stops. I really think that i need to see my OB/GYN and look into the PMS more. Thanks again for all the comments - now i dont feel so crazy! F 33 2 months
12/17/2007
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 2  bipolar II/mainly depression I became increasingly angry an irrational. I thought about suicide constantly which was not a problem before the lamictal. One night I raged at my husband and threw things. Socially, I behaved as if I had Borderline Personality Disorder and was convinced for a while that I did have it. When I was eventually hospitalized for depression I was paranoid and confrontational until the Dr took me off of it. Memory loss was severe. As with other meds, my doctors insisted that Lamictal could not cause these side effects. I was not taken off of it until a friend and my husband testified to my dramatic personality change. My friend even had it marked on his calendar. This was the worst summer I have ever had. It seems like medicines will sometimes make me worse and the doctor will decide that what I need is more of it. I am glad that it works for so many people, but be careful. F 35 2 months
2/23/2008
 2  Bipolar II Acne. Flat affect. Itchy skins upon raising dose, but that went away. After almost two months on the meds I have little side effects. The bad skin and flat affect have been what's remained. I do not feel like it is helping my mood enough to be worth taking. F 27 2 months
12/25/2007
 2  Major depression/OCD I had extreme thirst and dry mouth, fatigue and vision problems. I also had problems with retention and memory loss. I had numbness and tingling in my feet. I went to my doctor about these problems and was told that these systems would disappear in time. I later discovered that I had developed diabetes along with some kidney problems after being given a clean bill of health three months earlier for blood glucose, liver and kidney functions. I was hospitalized to get my sugar level down. There is no history of diabetes in my family. After I was diagnosed with diabetes, my doctor immediately took me off this medicine and put me on paxil. Lamictal might work well for some people, but not for me. None of the doctors that I asked about this drug considered it to be a risk for diabetes. F 58 2 months
3/18/2009
 2  Epilepsy flu symptoms, stiff neck, achy back muscles, daily headache, jaw pain, swollen lymph nodes, sore tongue, trouble finding words F 46 2 months
3/4/2014
 2  Major Depression/Anxiey NOS Boy do I STINK! I'm getting sick of smelling myself! Pretty much negates the benefits of bigger boobs. Did I mention the memory loss? I don't remember.... I think the numb-brain is going to boot me off of Lamictal, (at least 150mg/day). I forgot a psychiatrists appointment of all things. I was a bit scattered before I started, but now I'm barely functional, like getting to the car without my keys in hand. It takes me a good 20 seconds to remeber what day of the week it is. Foregetting the kid is pretty much a deal breaker for me. Mindfulness, my @$$. F 38 2 months
7/29/2006
 2  Major Depression, Anxiety NOS Memory loss! Lethargy/fatigue. Foot & leg pain every time I stand up. Typos like nobody's business. My conversation is necessary business only - not sure if it's because I can't think or if it's because I don't care. I think my boobs are bigger too; my pre-pregnancy bras fit now. Isolating. Female "sexual side effects." ERGH! Titrating up & at 150mg 1/day. Also on Wellbutrin 150-300mg/day =D *if i remember my pm dose.* I also just stopped 2.5 mg Zyprexa (sleep & anxiety) to isolate SEs. I formerly never had a problem remebering meds. Once I forgot to pick up my daughter; there's nothing so terrifying as hearing your spouse say. "Where's Olivia?" I think I am sight-reading at the piano better, which might be because I'm thinking less and just doing it - no more thinking about other possibilities, in music or in life. I'm able to do things that used to make me anxious because I just don't care, but I still lie awake at night having my awful obessive morbid thoughts. I am feeing guilt, shame and anxiety about not being "normal" and about not doing anything with my day. I'm very confilicted & frustrated. F 38 2 months
7/29/2006

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