LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  bipolar 1 severe headache and neck pain 3 days after increasing to 100mg, i am now having very bad leg pains in my calf's and outer thighs, it feels as if i have been mountain climbing because that is how sore my legs are.that is making me a little anxious. the leg thing has started abot 7 days after the increase to 100mg so i am not sure f they are related and it scares me if any one can help me plese email me F 35 40 days
7/4/2006
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 2  mood disorder verrry dry mouth, felt very unbalanced during exercise. At 200 mg, this drug worked for the first week but nothing after that. F 41 40 days
2/17/2006
 2  Bi Polar - Racing Thoughts TERRIBLE Muscle spasms, trouble seeing at night, blurred vision, muscle soreness, cramping muscles ( I am physically active and I'd get cramps after 5 min of walking in feet and legs when taking lamictal) Vivid horrible nightmares that feel real, feeling completely indifferent. almost 2 months ago I started lamictal combined with celexa and it's been increasingly miserable for me ever since i started. After 3 weeks I started taking 50 Mg a day but went back to 25 quickly after the side effects i listed all got far worse and I would feel terribly sick and feel like fainting. Since going back to 25 the side effects are still pretty bad and I'm simply waiting to see my doctor again to switch to something else. It indeed does help with Racing thoughts but these side effects are sometimes debilitating especially the muscle spasms and pain. Not worth taking at all. Feels like there are bruises forming on my arms at all times. M 22 40 days
25 MG 1X day
4/28/2012
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 1  Epilepsy Night sweats, insomnia, blurred memory, anxiety, comprehension difficulty, flat affect My experience with lamictal was very distressing. While at first I thought it was helping subdue my morning epileptic auras, it's effects made me feel very frightened about ANY mental stability, anxious indeed. Because of the night sweats and insomnia, I am certain that lamictal was directly responsible for a recent seizure. My doctor suggested I take an additional 100 mg atop my daily 400 mgs. After experiencing a most scary mindset that I would have another seizure, I decided to retain my prescription of dilantin, which has adequately treated my seizures for 24 years. There was no other better feeling once I began, again, the very first 100 mg of dilantin. I slowly weaned myself daily of 50 and then 25 mg of the lamictal. Oddly, I has taken about three weeks to completely rid myself of its dire effects of memory loss and concentration. M 41 40 days
11/8/2006
 4  Possibly Bi-Polar II Slight heart burn, Extreme heart burn when drinking alcohol (which has made me cut back on drinking; a blessing in disquise I guess). Its not certain yet whether or not I suffer from bi-polar II disorder, but my Dr decided to treat me with Lamictal to see if it helped my sever depression/anxiety. I delayed treatment even though I was severly depressed for a long period of time becuase of my past experiences with anti-depressants/anxiety medication. I have taken Zoloft, Zeprexa, Klonapin, and Cymbalta in the past (when I was 17 - 18 years old). Even though I didn't take the Cymbalta long enough to let it work, the other medications worsened my depression to an extreme point where I wasn't myself at all. It even landed me in jail (I was so drugged out on the dose my doctor was giving me at the time, I didn't even remember what I did, or that I was even in jail). I totally don't trust any Doctor to prescribe these types of anti-depressant and anti anxiety medications because I feel that they don't monitor their patients well enough, and get happy with the prescription pad. Even though I initially sought help with t F 23 39 days
2/28/2009
 5  moodswings and anxiety I quit Wellbutrin and started Lamictal. Now I'm warm for the first time in my life. Unfortunately, I lost quite a bit of sexual responsiveness, either from quitting the Wellbutrin or from taking Lamictal (or both). No other side effects, except that food tastes absolutely delicious now, which is very enjoyable, but of course I have to be careful about gaining weight. This is a miracle drug for me. I am free of all the anxiety and irritability that were making my life a living hell. I am free of the shame and self-hate, and I even have confidence in myself now. The moods have leveled out pretty well -- there's still a slight up and down but nothing compared to what it was. I am also free of the alternating loving and loathing of my partner. I think this has saved my relationship -- no small thing! F 50 37 days
2/25/2007
 5  moodswings and anxiety As far as working out, I seem to have more energy than before. No other workout changes so far. F 50 37 days
2/25/2007
 5  Depression A bit of sleepiness at 25mg. Lucid dreams when I go up in dosage. I just went up to 100 mg two days ago. So far so good. Few side effects. Happier, more stable, fewer crying spells, less concerned about issues that would have "taken me down" before. I hope it lasts. F 49 35 days
1/21/2006
 4  Bipolar II - rapid cyling very few, biggest problem is insomnia, although it's partly because I take it later in the day, and I believe once I start to take it consistantly in the morning this will be diminished - taking OTC sleeping pills have helped. When I remember to take it in the morning it makes me pleasantly perky and alert during the day. Only a few cases of short-term memory loss, although I don't know if this will increase as I titrate to a higher dose (just started 100mg from 50mg). Have had a few very short breakthrough episodes, which were the most noticable when I accidentally missed a dose (onset coming about a day after the missed dose, lasting a few hours, usually tending towards hypomania rather than depression). Generally have felt much more even and stable-headed. Overall I have really liked Lamictal, and have had very few side-effects which bother me - the most troublesome being difficultly in getting to sleep, which as increased with higher doses. I started on 25mg, titrating up to 100mg after 30 days, although I felt stablizing effects almost immediately. I have felt more even-headed than before I can remember - I was previously cyclothimic since age 11, recently changed to BPII a year ago - this is my first attempt at medication. I am currently taking this as monotherapy, although I may add medication if my depression returns. When I started the medication I was already beginning to come out of a year long depression, so I am not as certain as to how affective it will be for deeper depression, although it has significantly reduced my frequent recurring morbid depressed thought episodes. The few minor short breakthrough episodes I've had have been almost exclusively tending towards hypomania. Overall I've been very impressed with how much mor F 18 35 days
10/30/2006
 3  Major Depression, Perimenopause Up to 50mgs, no side effects 100 mgs daily...very sleepy. Had to take at night. When I started Lamictal the first month I thought it was a miracle. I felt solid and didn't even think about how I felt. Then I got my period and increased my dose. All my Depression can back worse than before. I am not diagnosed BP but my hormone flucuations mimic it. I'm hoping the higher dose will pull me through my next period with less depression. The depression hasn't let up yet so it better hurry up. I'm also on Lithium and Zoloft. Worked for years until I hit Perimenopause. Now it's like I'm starting all over again. F 46 35 days
4/17/2008
 3  bipolar 1st few weeks very angry feeling--extreme rage ( not sure if it was from the Lamictal or the Lexapro--stopped though in the third week of taking med);boughts of sleeping alot and then not. Stomach is very upset. Extremely clumsy for about 1 wk (let me say clumsier than I usually am) Pretty much like everybody else diagnosed, I am constantly on the change your meds rollercoaster. Usually more than one medication is changed at a time so it is difficult to tell what side effects are from what med or if I am just not feeling well or having a bad period (cramps for that seem to be worse).I'm slowly being taken off Trileptal while my dose of Lamictal is decided on, was taken off Prozac (which by the way does not work in gereric form and since that is all insurance will cover, I had to start looking for something else)Lexapro was added and that didn't work, so I'm REALLY counting on this drug to give me a better life. (I'm just finishing with the starter pack.) Trileptal took away all of the mania but did nothing for the depression (I've been on that 2 yrs and finally told the doctor to get me off of it.) Lamictal is supposed to cover the area of depression and that is what seems to bother me the most. I honestly pray to God that this drug will work; I've not been suic F 39 33 days
2/6/2006
 2  seizure weight gain,headaches(gone after I increased to 100 mg),joint pain,loss of sex drive,fatigue,tingling and numbness in fingers,anxiety,occasional insomnia I've had one Grand Mal seizure in my life last October,the doctor did two follow up EEGs and found more seizure activity during the EEG but has no idea why I would have my first seizure at age 41(no drug abuse,no alcoholism,etc). I was on Wellbutrin for depression but stopped that a week or so AFTER the seizure. I really don't like this drug and as far as I am concerned I don't need to be on it and the side effects suck for me! The only other drug I am taking is 100mg Cozaar daily for HBP. Any other opinions on this would be welcome. M 41 31 days
1/22/2007
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 5  Depression None I have been depressed almost all my life. I finally admitted it to myself and that it wasn't normal (you'd think I could have figured that out before now - I'm 46, but there you are). The only way I can describe it is being like a "walking wound" and having a "glass is half empty" attitude. I'd been on Zoloft and was still on Wellbutrin when I started this (and still am) but they didn't seem to do a lot. Wellbutrin helped some with energy but that was it. I talked to my therapist and he said he thought I might be bipolar. I am NOT manic in that I don't have "highs" only constant low and then periods of DEEP lows. He explained that there is a type of bipolar like that, but I had no idea. Frankly, I don't care what I am labeled. Anyway, I went to a psychiatrist to be eval'd for a med and she put me on Lamictal. It has been wonderful! I am not "happy" per se but I also am not stuck with that "walking wound" feeling. I can handl M 46 30 days
6/23/2006
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 5  OCD/Mood Swings/Depression Constipation - went away after a week. Mild headaches, also went away after a week. Slight hair thinning, but not enough for me to freak out about. I love this medication! I am taking it with Prozac and Vyvanse. I'm 37 and have struggled for almost a decade to try and find the right combination of meds for me.... what I am on now has been a LIFESAVER! Clearer thinking, less dwelling on negative thoughts, ability to maintain organization (ie office paperwork, checkbook balancing, etc) Currently on 50 mg but Dr. is going to up me to 100 mg next month. I feel like a brand new person!!! Can't imagine how I've lasted so long before without it! F 37 30 days
50 1X day
3/10/2010
 4  BP 2 , Borderline Initially : cold.from the inside and out-mentally tired,not sleepy-I just had to hide for an hour or so to go on again. Dry facial skin,but thats taken care of using zinc/selenium xtras,and a fatty cream. Major change in regards of depressive symptoms! I`m experiencing a feeling of being "normal" in my reactions-for the first time since age twelve :)! Slight increase in hypo reactions,but without "going bonkers".. Time to look at my borderlinethoughts and adjust my thinking instead of exploding- HURRAY !! M 44 30 days
100mg 1X day
2/5/2010
 4  MOOD STABILIZATION BLADDER SPASMS, URINARY TRACT INFECTION SYMPTOMS F 46 30 days
11/14/2005
 4  Bipolar NOS dry mouth,fine hand tremors, unquenchable thirst at times, but seems to be improved if caffeine/salt limited. Some decrease in mental functioning-recall,names,etc.on 100mg currently and feel no depression, less irritable definately. none F 27 30 days
5/5/2005
 4  seizure disorder Increased sweating and possibly complexion problems (excessively dry skin on my face) although I am not completely sure that the two are directly related I have been at 200mg twice a day for 4 weeks and I am finally weaned of the trileptal that I was taking previously. I can say that I have a lot more energy on Lamictal compared to Trileptal and I am extremely hopeful. F 31 30 days
4/8/2005
 4  bipolar/ADD I started taking Adderall and Strattera simultaneously, so not exactly sure which of these goes with the Lamictal, but I've been on the other two before so I think I've isolated these to Lamictal. Experiencing some hair loss, dry mouth, increased sweat - more greasyness, actually - and some deterioration in mental acuity. The biggest problem for me, however, is the increased libido combined with total sexual dysfunction. Anybody else? It really doesn't seem like a common side effect. Great improvement in mood. 100% change. Even within a week or 2, I went from having 4+ crying fits daily to really enjoying life again. Given all the problems that people who have been on it for longer seem to have, though, I'm a little nervous about staying on it for too long. F 26 30 days
7/17/2007
 4  Depression/bipolar Had the 25 mg dose and was fine with a little sleepiness and then went to 50 mg and got horrible spotty rash...don't think it's dermatitis either and had to get off of it. I have to say that it was a great drug and felt the difference immediately. I was sad to get off of it but the rash was just unbareable enough and would get some really intense headaches. Now on Cymbalta and it doesn't even compare... F 35 30 days
9/10/2007

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