SULFASALAZINE Reviews (SULFASALAZINE)

Average Rating: 2.1 (80 Ratings)

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 GASTROINTESTINAL, MISCELLANEOUS

 Type: Rx Drug

  

SULFASALAZINE  (SULFASALAZINE):  Sulfasalazine is used to treat a certain type of bowel disease called ulcerative colitis. This medication does not cure this condition, but it helps decrease symptoms such as fever, stomach pain, diarrhea, and rectal bleeding. After an attack is treated, sulfasalazine is also used to increase the amount of time between attacks. This medication works by reducing irritation and swelling in the large intestines. In addition, delayed-release tablets of sulfasalazine are used to treat rheumatoid arthritis. Sulfasalazine helps to reduce joint pain, swelling, and stiffness. Early treatment of rheumatoid arthritis with sulfasalazine helps to reduce/prevent further joint damage so you can do more of your normal daily activities. This medication is used with other drugs, rest, and physical therapy in patients who have not responded to other medications (salicylates, nonsteroidal anti-inflammatory drugs-NSAIDs).    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SULFASALAZINE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SULFASALAZINECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Rheumatoid arthritis I have not found any decrease in joint pain.. it has started to effect my mood greatly. I feel so depressed and have high anxiety.. so fed up of trying new meds without success The fact the medication smells like paint/ nail varnish when you open the container alarms me F 51 80 days
1000 x2
6/6/2020
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 2  Rheumatoid Arthritis Nausea, extreme fatigue, headaches, depression, to tired to do anything ,feeling hopeless I just wanted to sleep all day I also was EXTREMELY thirsty all the time F 54 4 months
500mg 4x a
5/7/2020
 1  Spondylitis Depression, anxiety, fatigue, nausea, fearful I was supposed to slowly increase this medication each week but after 3 weeks I was taking 2 in the am and 2 in the pm. I became suicidal, got into a physical altercation (1st ever), and had a general feeling of nervousness and fear. I was irrational. It is so embarrassing now to think of my behavior. F 45 3 weeks
1,000 mg
4/30/2020
Email
 1  Rheumatoid arthritis Depression muscle fatigue, joint pain The drug is supposed to help RA but has done nothing. Today is the day I stop taking them regardless of what the Dr advise. Cannot go on like this. F 62 8 months
500
3/5/2020
 1  Crohns and spondylitis Severe anxiety and depression came on when dose hit 1000 mg. Have stayed with it hoping this would abate, but getting worse. May continue another couple weeks as I really want this to work F 63 21 days
1500 mg
2/17/2020
 2  BOWEL INFLAMMATORY DISEASE (BID) I experience mood changes, I can't concentrate well as I used before and I feel it is going to be dangerous to me I think the manufacturer should find the way of removing some ingredients which cause this complications when they are manufacturing this product F 29 2 months
500 MG
2/8/2020
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 1  Joint pain/autoimmune Extreme joint pain, fatigue, depression, diff colored urine and less output, heart palpitations It was the worse drug I have ever taken. Withing 2 days the pain was everywhere. It felt like someone had taken a hammer to all my joints. I felt suicidal and I just wanted to sleep. Within 2 days of coming off this drug all the symptoms had dissapeared. I was a pain level 2-3 before and this was a 13. I had to go to the emergency room. F 32 7 days
1/29/2020
 3  Reactive Arthritis Altered sense of taste and smell. Depressed. F 62 90 days
3000 MG
1/28/2020
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 1  Psoriatic Arthritis I started off slowly just 1 a day gradually increasing to 4 a day. Started feeling not myself at all extreme fatigue and feeling depressed not wanting to talk to anyone feeling sad all the time not looking forward to anything. I am going to stop this medicine as mentally not doing me any good at all. F 49 10 days
2000
12/19/2019
Email
 1  Inflammatory arthritis Nausea. Depression. Stay away from this drug. I had been suffering from depression for years and antidepressants had helped enormously. Soon after starting this drug the depression came back with full force even though I was still on antidepressants. Soon after stopping it I was back to normal. M 32 21 days
12/2/2019
 2  Psoriatic Arthritis Increased swelling, fatigue and pain. Very loose stools. Doctor stopped therapy. Took dose pack, methotrexate and folate now. I felt better the first day. Don’t know if methotrexate will help, but since the dose pack I am a different person! I felt like an inflatable in someone’s front yard! Not as bloated feeling now! Thank you Lord! F 60 2 months
2000mg
11/21/2019
 1  Autoimmune illness Depression I developed rapid depression while taking this medication. I know everyone is different but this affected me very negatively. My husband noticed my mood change before I did. Then I was so down I almost didn’t realize it could be the meds. I knew it was bad because the things that made me happy all seemed useless. I was so angry and depressed feeling. Discontinued and within 48 hours starting to feel myself again. Disappointed because I was hoping it would help with my joint pain and fatigue but nothing is worth getting horribly depressed over. F 50 5 days
11/1/2019
 5  Crohn's and arthritis None. If anything my stomach isn't nearly as bloated. It's helped me so much I can't believe it. This has been a lifesaving miracle drug for me. It's an anti inflammatory, how it's supposed to cause emotional issues it beyond me. It has actually saved my life. Before trying this, the Crohn's was so painful I didn't think life was worth living anymore but a week after starting this, I have my life back for the first time in a long time. It's eased my joint pain and keeps me from being bent over double in pain every day. F 48 1 years
500 3X day
10/30/2019
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 3  Ankylosing spondylities Dry eyes, early fever, early nightmares, smelly breath, change of hear beat, early fatigue It has reduced CRP significantlly, joint pain reduced but not a lot, has re-started the Crohn's, improved night sleep, better mood after 4 weeks of taking the drug M 40 2 months
2000 day
7/13/2019
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 2  Joint pain Dropped my WBC count. Had even greater susceptibility to infection than normal. Gained several pounds within the first two weeks of starting it (weight had been absolutely steady for at least 6 months prior). I believe it also worsened my depression/anxiety. All of these things have been improving since I stopped this med about three weeks ago. It’s important to note that my normally very reasonable rheum refused to believe this medication had anything to do with the increased infections, weight gain and mood changes. On top of these side effects, this medication did not help me at all. Some days I felt like it made my joint pain worse. Plaquenil has its own issues, but that drug has been a miracle for me these last five years I’ve taken it— so I am willing to deal with its side effects. People: of course listen to your doctor, but above all else, LISTEN TO YOUR OWN BODY. You know it better than any doctor or list of side effects that the drug manufacturer publishes. F 39 6 months
2000
7/5/2019
 1  Arthritis I became infertility was having problems keeping my partner happy stopped medication Never take it dnt no after how long will get better M 41 5 months
100mg
6/30/2019
 1  Rheumatoid Arthritis Severe increase in joint pain Pain all over Suicidal thoughts for first time EVER Extreme fatigue Bad pains in chest when breathing - will go to the docs when I can walk again F 45 14 days
1000 2X day
6/18/2019
 1  Joint pain, ehlers danlos Increased my pain. Joints swollen. Extreme fatigue, feel like legs and arms are so heavy. Nausea. Over all ill feeling. F 51 1 weeks
2000 mg
4/15/2019
 1  Autoimmune arthritis • Initially felt a giddy feeling • I recall telling my husband I felt like I had this strange anxious feeling • Mood swings started coming on about a month or two into treatment • I had told my rheumatologist re mood swings worsening as this was out of character and he played it down as though it's something need to put up with give it more time Etc • Moods worsened - I became very depressed bit by bit, very isolated, started believing My family would be better off without me as I'd lost my independence and this drug genuinely made me feel like I was a burden on them • started having thoughts about suicide to which my mother told my rheumatologist to get me off sulfasalazine immediately • Had to be weaned off it but noticed improvement in mood as soon as this happened • I was incredibly lucky to have family help me but by that stage I was so lost and had given up hope so please notice these changes and stop immediately if you start feeling any mood changes to avoid the heartache I went through • I lost a year of my life with this medication which not only DIDNT help me, it caused me more problems and almost cost me my life BE VERY CAREFUL! ALMOST COST ME MY LIFE! And it should be noted that I was not given ANY warning that this could be a possible side effect. Rare or not, it is IMPORTANT that you understand this risk!!! F 34 12 months
3/23/2018
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 1  Ra Extreme fatigue. Couldn't go to work and had to stop the drug F 55 2 weeks
2000
10/28/2017
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