BYETTA Reviews (EXENATIDE SYNTHETIC)

Average Rating: 3.6 (206 Ratings)

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 BLOOD GLUCOSE REGULATORS

 Type: Rx Drug

  

BYETTA  (EXENATIDE SYNTHETIC):  Exenatide is used with a proper diet and exercise program to control high blood sugar. It is used by people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Exenatide is a diabetes drug that is similar to a natural hormone in your body (incretin). It works by increasing insulin release (especially after a meal) and decreasing the amount of sugar your liver makes. It also slows down food digestion in your stomach, decreases the amount of sugar absorbed from food, and may help decrease your appetite.   FDA Approval Date: 2005-04-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Date added.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR BYETTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Type II Diabetes A very small amount of nausea the first couple of days, heartburn very bad at first but now I have it maybe a couple times a week. If you eat right and within a half an hour after you take the Byetta heartburn usually does not happen. I have lost 80 pounds since being on Byetta, but most important my glucose runs in pretty much normal levels now. I started on 5 mg, twice a day along with one 10 mg Glyburide twice a day. I have been on Byetta for about 2 and a half years now and for about 2 years of that I have been taking 10 mg of Byetta and my Glyburide has been cut to 5 mg twice a day. My glucose runs most of the time within normal levels and I have very few times of my glucose dropping too low. I have went from 275 pounds to 195 and I am still losing slowly. have totally changed my eating habits because I just don't feel hungry. The only long term side effect I have noticed is heartburn a couple times a week and it is getting less as time goes on. I recommend Byetta. F 56 34 months
11/21/2008
 3  my wife is she complains of a lack of hunger but is thrilled to be skinnier than when she was 18. the lack of hunger also translates to a lack of sex drive - anyone else out there find no interest in sex because you just can't orgasm? Prefer to hear the female take as I want to help my wife any way I can - I can't go without for much longer it's been over a year and it's having an effect on our relationship!!! M 34 1 years
11/17/2008
 3  Type II Diabetes With dose of 5, once a day, no problems and better blood sugar readings in AM. However, Doc increased Byetta to dose of 10 before breakfast and evening meal, for a total of 20/day. Ugh! Severe stomach acid problems that last all day and wake me up in the middle of the night. Only marginal relief with OTC remedies. Severe daytime fatigue. Appetite zero. However, I lost 30 lbs in six months 285 to 255, at a steady rate of 5 lbs./mo. I appreciate the weight loss but the excess stomach acid is just too much. I'm dropping my dose to 5 a day and be done with it. Anyone else with this problem? Drop me a line. Byetta is like playing the stock market: Most people have the brains for it, but few have the stomach for it. M 61 6 months
11/15/2008
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 3  Type II Diabetes Extreme Nausea I took the 5mg shot for one month and did finally lose the nausea, but no weight. My doctor now has me on 10mg shot plus 500mg Metformin. I am losing some weight,but the nausea is still pretty terrible. I can hang in there if there is some light at the end of the tunnel. Can anyone tell me if their nausea went away after three months? F 69 2 months
11/15/2008
 3  Type II Diabetes nausea, stomach cramps, fatigue, sweats, headache This is my 2nd time on Byetta. It does help with appetite control, but the side effects have really gotten me down. The 5 mcg dose had less side effects, but also less appetite control. F 65 8 months
11/9/2008
 4  Insulin resistance Nausea, bruising at site of injection and on legs, weight loss, dizziness if I do not eat within 30 minutes of injection, excessive thirst. Overall, I am so glad I started taking Byetta. I feel much better now. Previously I tried to take Glucophage and I felt sooo bad when I was taking that. I have experienced some nausea but I'm learning more now that it's controlled if I eat like I'm supposed to. There has been some bruising at the injection sites sometimes but the doctor states that it is normal and it can't be prevented. I have not weighed myself since taking it but everyone comments that I'm loosing weight. My clothes feel looser and I feel like I have more energy now. It's wonderful. I recommend it to anyone with insulin resistance. F 33 21 days
11/5/2008
 4  Type 2 diabetes Some mild nausea, no vomiting. Fatigue. So far just on the 5 dose. Will start with 10 dose next month. I can deal ok with the mild nausea. The fatigue is almost crushing. It feels like the fatigue I experienced during my first trimester of pregnancy. You just want to roll up into a little ball and sleep, anywhere, anytime. Haven't checked for weight loss yet, but clothes are a bit looser. Glucose readings are MUCH better, still just high fasting in the morning, but even there much improved. F 59 9 days
11/2/2008
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 5  weight loss nausea if i don't eat within 30 minutes. Now after losing 100 pounds from byetta. I still have to battle sugar cravings but the medicine really does not let me overeat. I regret it severely if I try. M 42 8 months
10/31/2008
 4  Type 2 Nausea On my first week (the 5 dose). Also on Meta 1000MG x 1 a day, and 30/4MG Duetact at lunch. Definately getting the nausea, but only have gotten sick once. Feeling the appetite decrease, but figuring out quickly that if I over eat in the slightest I am miserable for hours. Morning sugars have been my issue but this morning ran a 110. First time I've ever been that low fasting in the morning. I'm fighting the urge to jump on the scale every day to see what the weight loss is. On the first 2 meds I have spent HOURS and HOURS every week lifting weights and jogging to only see a couple of pounds every month come off. Keeping my fingers crossed. Also, thank you to who posted that salads were not agreeing with them...Same here, I am used to eating some daily and may need to find an alternative. I burp it for hours after I eat it now. M 37 4 days
10/22/2008
 5  type 2 diabetes some nausea, heartburn in the 11 months since starting Byetta the side effects are minimal, and I went from 205 to 184 lbs. without exercising, I hate to exercise, however I do alot of gardening. works for me. mike M 63 11 months
10/17/2008
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 3  Type II Diabetes and Weight Loss Nausea, dizziness, weakness, fatigue. Also feeling very disorientated. Definitely a suppressed appetite, don't want to eat anything and am forcing food down because I have taken the shot. Lots of reflux type problems and bilious. Very thirsty, but can't seem to drink quickly, have to sip things as though my throat is smaller. Have lost 5lbs in 5 days, so the weight loss is fantastic if it continues. No probs taking the shot, I was on 8 large Insulin injections a day so to drop down to 2 tiny ones is fabulous. No lowering of my glucose levels yet, they are very high as I am off all doses of insulin so they are coming in at 17.0-22.9. Hopefully this will kick in soon. I really want this to work, I NEED to lose my weight and get my levels under control. F 42 5 days
10/10/2008
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 3  weight loss Mild nausea and tiredness, now after one week had two headaches and I'm not a headache kind of person. came on computer and found this site to see if others were having the same problem. Sugars have been doing great since starting januvia and avandamet. Byetta added cuz i want to lose about 40 lbs. still. doctor thinks it will help. just from the first 2 meds my fastings have gone from avg. 155-180 to 105-115. hoping byetta will give the added kick I need. I play tennis and did have a significant drop in sugar once. Jitters, sweats, etc. found it was 58. Oops. Only one week so hard to rate yet but like the comments about the weight loss of others and looking forward to the same results for self. F 48 7 days
10/10/2008
 4  PCOS, Weight Loss Nausea, vomiting when first started 5 mcg and then when upped to 10 mcg. Sleepiness about an hour after I take the shot. Diarrhea until I get used to the new dosage. Loss of appetite and desire to drink Once I got used to the side effects I LOVE it. I love how it take care of the crazy hunger I had, and how easily I am dropping weight. 13 lbs so far. After reading the other comments, I finally linked my tiredness after the shot to actually taking the shot, so I will be careful not to drive then. F 39 10 weeks
9/5/2008
 4  type 2 diabetes Losing weight - less urgent needs to eat, full quicker. Seem to be more sleepy. Itching lower legs Not sure if itching legs are related, wonder if anyone else has felt this M 40 50 days
8/30/2008
 5  Type II nausea, gas pains about every 2 days and then diarreha, and bruising at the injection site. I absolutely love BYETTA!!! I no longer constantly think about food. It controls my appetite. The pills, metphormin, and glimpride have made me gain weight and be bloated. I would take the nausea, gas pains, diarreha, and bruising over gaining weight, and feeling bloated. I have lost approx. 5 lbs so far in just a short amount of time, my blood sugars each day are lower and lower. I am on 10 mcg. twice a day. F 44 8 days
8/21/2008
 5  Type II Noting noted at this time. Never felt better. finally feel refreshed after a nights sleep. No longer tired after eating. M 45 7 days
8/19/2008
 5  Type Two Diabetes The only side effect that I experience is the nausea. I have learned to take the Byetta shot, eat, and then take my other meds. It just seemed to cut down on the nausea so much when I seperated the shot and the pills with my meal. It has helped me to better control my A1C. It is 5.7 with the Byetta 10 twice a day and 2 metformin 1000 XR per day. As my weight went down the metformin was reduced to 500 twice a day. I have went from 236 lbs to 196 lbs (40 pounds lost) at this point. I had trouble getting my insurance company to ok this for me and was off of it for 4 months...just on metformin...and I was hungry all the time and gained some weight back along with my A1C being 7.4! Now I am back on Byetta/metformin and I have energy and feel so much better. I am a little concerned about the pancreatitis possibility. Would like more info on that. I had a grandmother, father, and brother all with diabetes. Thanks to Byetta for giving diabetics a new lease on life. Had my eye exam this week and eyes were very healthy, BP is under control. I feel that I have been blessed to have this come along in my lifetime...my relatives were not so fortunate. F 65 14 months
8/19/2008
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 4  pre-diabetic and weight loss I guess I've been one of the lucky ones. I've had almost all of the symptoms mentioned but none were severe. I started with the nausea which I still have but not as bad or as often and the stomach cramps and upset bowels at least once or twice a week. I've also had the rapid heart rate although not much. I have times when I burp alot and usually foul smelling. On the other hand, I've lost 64 lbs. and don't crave food like I used to. I don't have that nervous, got-to-eat-something feeling anymore. My portions are smaller because I know when I've had enough. If I eat more than that, I feel awful. I lost quickly at first but have slowed down now. My doctor has encouraged exercise which would speed the weight loss up but I haven't done much of it. My blood sugar stays pretty much around 100 unless I eat the wrong foods. I take Byetta along with Glucophage. Together they have worked wonders for me. I have been extremely overweight since I was pregnant 15 years ago. I knew immediately after giving birth that something had changed in my body. I had always been overweight but never as severely as I am now. Dieting was always difficult but I could do it. After pregnancy, it was impossible no matter what I tried. Byetta was my miracle drug. I still need to lose another 150 lbs. so I hope I can continue to take it with good results for a while longer. F 53 18 months
8/19/2008
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 4  Type 2 Diabetes Nausea and vomiting especialy if I don't eat immediately after taking the Byetta. I feel fatigue anyway, and I think that's the diabetes. I have the nausea especially if I eat something that's too high in carbohydate or fat. I've lost over 30 pounds. My Hemoglobin Alc has gone from 8.8 down to 6.2. I've been at 6.2 for over a year. F 56 18 months
8/15/2008
 4  DM 2 Nausea in the evenings and/or after a regular or large meal. Also often get a bruise at the injection site. Diarrhea off and on, usually improves with one immodium pill. I can't chew sugarless gum anymore either. Greatly decreased appetite. All my life I woke up feeling starved but now I don't even feel hungry when I wake up. About once a week I skip an evening dose, and really don't see much change in my sugar levels with just that one missed dose. Recently I forgot my Byetta at the cabin and was without it for a week, and had to really work like crazy on diet and exercise to keep my sugars from going nuts, so do appreciate the Byetta after having gone through that. F 55 4 months
8/13/2008

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