BYETTA Reviews (EXENATIDE SYNTHETIC)

Average Rating: 3.6 (206 Ratings)

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 Type: Rx Drug

  

BYETTA  (EXENATIDE SYNTHETIC):  Exenatide is used with a proper diet and exercise program to control high blood sugar. It is used by people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Exenatide is a diabetes drug that is similar to a natural hormone in your body (incretin). It works by increasing insulin release (especially after a meal) and decreasing the amount of sugar your liver makes. It also slows down food digestion in your stomach, decreases the amount of sugar absorbed from food, and may help decrease your appetite.   FDA Approval Date: 2005-04-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR BYETTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Type 2 diabetes The first week, extreme nausea. After that not so much, but feel very tired and have swollen legs with knee problems. If I overeat,it is miserable and don't want to eat for almost 24 hours. Side effects are tolerable. Have lost 13 pounds in the month on it. It is worth the weight loss. I also take 20 units of Lantus at bedtime, the 5 Byetta twice a day and 1000 metformin twice a day and 1/2 glipizide a day. Blood sugars are great-sometimes a bit low-probably due to the glipizide. That's why cut to 1/2. F 56 1 months
1/8/2010
 4  type 2 diabetes At the beginning heartburn, nausea an dhiarrea. Then it settled, now it's mostly flatulence. A month ago I started notice pink sediment on my shirt's neck at the end of the day. Anyone else? I take a combination of Actos, metformine and glibomet along with byetta. So far weight loss is not relevant, however A1C went from 9.3 to 6.8. M 57 9 months
1/1/2010
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 5  T-2 Diabetes Lost of appetite,changes in food that I like, no desire for meat, take 10MG twice a day, lost 33 pounds so far, no nausea or vomiting A little problem with constipation,had reflux problem , Dr put me on medication for that, no problem now, I have started to get little red itching bumps on my lower extremities only a few at a time, they go away in about a week. I turn my nose up at most foods. Morning shot dosn't seem to hold my hunger as long as the evening shot , All my Fasting blood in every category has come way down. Very happy with weight loos down from 265 to 232 only 12 pound over my air force weight now. don't know if weight loss will stop, i hope not. AIC now 6.6, I don't sleep well at night , dream a lot and wake up off and on. Don't experience other problems people have such as nausea, vomiting, dizziness, usually have a snack around 10-11 in morning and eat my lunch at 1:00 PM, small supper around 5:30PM, Cottage cheese with low fat Fruit about an hour before bedtime. M 68 9 months
12/7/2009
 5  Type II Diabetes After 6 months, I had better A1C numbers, but had not lost a single pound. Low grade nausea, accompanied by some diarrea. But then it kicked in and I have lost 17 pounds in 2 months. Cannot eat any fats at all, no beef or pork. Can tolerate only small amounts or chicken or fish. And if I let the amount of carbs exceed about 1/2 cup, then I am up all night. I feel like all I want is fresh fruits - which is GOOD! Nausea is pervasive. But it was when I was pregnant, and I ended up with the greatest gifts of all. So I take this nausea as a 'gift' too. If it helps to loose the weight and get those numbers where they ought to be, then I am blessed! I take the 10mcg. twice daily and per doctor's orders, wait a full 60 minutes before eating. F 56 7 months
12/4/2009
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 1  type II diabetes No bm x 9 days. Complete ileus... severe crushing chest pain from esophogeal spasms frequently with constant nausea and vomiting. Had to stop!!!!! Be very sure you have a completley normal GI tract or watch out! F 55 10 days
11/13/2009
 3  type 2 diabites slight nausea,itchy red patches lower left leg,from knee to sock line.always injected to right abdomen for 6 months,had right rear back pain.Switched injection to left abdoman,4 weeks later had back pinches on left side don't know if related 2 byetta shot. taking for 2 years , 10 mcg. 2 x day 30 min. before meals.also on metforman 1000 2 x day.Controls hunger very well! M 72 700 days
11/12/2009
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 5  Type II diabetes - oral meds N/G Some weight loss which was an added benefit. Witht the addition of Byetta to my oral meds I was able to keep an almost normal A1C and have had very problems with hypoglycemia which I had in the past. M 63 2 years
11/7/2009
 5  Type II diabetes - oral meds N/G Some weight loss which was an added benefit. With the addition of Byetta to my oral meds I was able to keep an almost normal A1C and have had very few problems with hypoglycemia which I had in the past. M 63 2 years
11/7/2009
 1  Type 2 diabetes Horrible nausea, regardless of when or how much I ate. Sleepiness. Intense depression lasting 4-6 hours after each shot. Gave up on it -- makes it impossible to lead a normal life! F 48 45 days
10/29/2009
 5  Diabetes type 2 5mg2 x dia first month, during first 2 weeks some queasiness, loss of appetite. 10mg 2 x dia second month no negative side effects. During first 12 months of therapy combined with exercise and healthy diet I lost 50 kilos from 135 to 85. I have maintained weight. I quit smoking 3 months ago with no weight gain. Blood sugar levels returned to normal range. My endocrinologist is keeping me on therapy to see if I will continue to regain functioning of pancreas. I am looking forward to changing to once a week version in January. M 57 19 months
10/26/2009
 4  diabetes No side effects for me! I haven't had any side effects whatsoever, during the nine months I have been on it. I have lost 55 lbs in that time. Decreased appetite dramatically! I was on 5 mg 2 x a day until recently when the doc upped it to 5mg in the morning and two 5mg shots at night. It hasn't made me have low blood sugar levels, and sometimes I have morning highs, but they have decreased by a late night snack. I am very satisfied with it and hope to lose another forty pounds. It is important to drink a lot of water and to take it at about the same time every day for the best results. F 58 9 months
10/7/2009
 4  Type 2 Diabetes & increased A1c I am and plan to remain on 5mg. For the first two months I had significant nausea and some vomiting, particularly if I at a higher carb meal. Some dizziness at various times of the day, not really associated with food or lack of food. I no longer desire food and can eat what I NEED, which has helped my blood sugar to average normal numbers. I lost about 6 pounds, however I am quite thin and don't want to lose much more. I have an unusual kind of type 2 as I'm not overweight, exercise regularly, am under 40, and tend to eat healthy items anyway. My menses has changed dramatically, however, and this has become a problem. I am not sure why, however the change started the month after I started using the drug. Not enough of a problem to stop the medication. I dislike the sting of the medicine upon injection and the bruising, however, I've used insulin before and it really isn't much different. I've found eating within 30 minutes of injection is the best. If I eat too early, I get overly ful I've read some information about acute pancreatitis (sp?) and have some concerns with continuing this drug. As long as the side effects don't get any worse, I will probably continue the drug. F 39 90 days
9/19/2009
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 3  pre-diabetes (type II) The main side effect is that I get diarrhea periodically. I believe there is a connection to this side effect and how much I eat (portion) and how fatty the food is. I also notice occasional fatigue and some dizziness. I have lost about 8 pounds in 30 days. Appetite has decreased. I went to 10 mcg. 2 weeks ago. I hope I can tolerate it as I need to lose the weight (about 30 more pounds). M 50 30 days
9/12/2009
 5  TYPE II Initially a slight bit of nausea with 5 mcg bid, but found that eating shortly after dose made a big difference and in between meals if I felt nausea it would go away in a few minutes or if I ate something like a cracker it would go immediately. Constipation for a few days, took fiber pills for about a week then back to normal. No other bad side effects. 7.5 lbs weight loss in less than a month with 5 mcg bid. Just increased to 10 mcg bid, have seen a slight increase in nausea, but not a real problem. Carb cravings non existent, smaller portions, full faster. All in all I am very pleased and today my fasting blood sugar was 98, the lowest ever. M 50 35 days
9/10/2009
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 4  DIABETES NONE IF I EAT RIGHT AWAY. M 70 18 months
9/10/2009
 3  Type II Diabetes Initial mild nausa for a couple of days. Severe hand swelling and finger tendonitis. I was on Metformin for a couple of years. My fasting blood sugar was still between 145 and 160 and my A1C went up to 7.1 so I started taking Byetta. Initially it was great, did a wonderful job of controling my blood sugars. However, I started having a severe problem with swelling of my fingers and hands. I was only able to take 500 mg of Metformin because of swelling of my fingers. I had to stop taking the drug and am very disappointed because it worked well for me regarding my BS. I was off all meds and tried Byetta again after a number of months. After one dose, my fingers stared to swell. Byetta did also help with losing weight. I have read about swelling of the lips, but never fingers. I was wondering if it was an allergic reaction. F 56 4 months
9/8/2009
 5  type 2 diabetes F 41
9/5/2009
 3  Type II diabetes I finally lost a little weight when we upped the dose to 10 mcg. However, my taste of food has changed. Everything but fresh fruit and veggies taste terrible. I'm having trouble fixing food for my family because just thinking about it makes me shudder. Didn't have trouble with metformin alone but when went to 10 mcg Byetta the trouble began. I've been on that does for 1 yr. F 64 1 years
9/2/2009
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 3  insulin resistance severe itching of scalp, nausea, heartburn, leg cramps/charley horses in calfs, cold chills Really helps with appetite, has changed the way I eat, much smaller portions and healthier snacks. Nausea bad sometimes, I will try to eat sooner after injection to see if that helps. Scalp itched terribly for first 4 weeks. Have only lost 5 pounds in 2 mos., hoping for a lot more. F 41 2 months
8/29/2009
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 3  type II/ PCOS Nausua 2-4 hrs post injection, bloating, belching, indigestion on occassion. Anxious feeling and being cold stopped 2 wks after initiation. Bruising of injection site and bruise really easy everywhere else. Anybody else bruising really easy? Must eat 30-45 min from injection or too sick to eat at all. Will try to eat after injection. On 5 and moving to 10 in 1 wk. Also actos+met 2x daily. Choices of food has drastically changed. Carb craving is gone! Too sick to eat much! Would love to hear from others "suffering" through the drug! F 37 3 weeks
8/27/2009
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