BYETTA Reviews (EXENATIDE SYNTHETIC)

Average Rating: 3.6 (206 Ratings)

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 Type: Rx Drug

  

BYETTA  (EXENATIDE SYNTHETIC):  Exenatide is used with a proper diet and exercise program to control high blood sugar. It is used by people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Exenatide is a diabetes drug that is similar to a natural hormone in your body (incretin). It works by increasing insulin release (especially after a meal) and decreasing the amount of sugar your liver makes. It also slows down food digestion in your stomach, decreases the amount of sugar absorbed from food, and may help decrease your appetite.   FDA Approval Date: 2005-04-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR BYETTACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Type 2 Diabetes Nausea, weakness, stomach pain, weight loss, constipation. I loved what the drug did for my blood glucose readings and weight. They were at or very near normal the entire time I was on it. However, my insurance refused to pay for it. Then when I changed carriers they would pay for it but it made me much more ill than the first time I used it. I am trying to slowing increase usage to see it that will help. F 52 6 months
4/17/2009
 5  Type 2 For the first couple of weeks I did have some nausea & felt jittery, but that is completely gone now. I love Byetta! I went from having BS routinely in the 300's (and often in the 400 range) to now having my diabetes completely under control. My fasting BS is always at the 90ish mark and NEVER do I have a BS over 150 -- even after eating. I do have low BS from time to time which was a new experience for me -- last night I had a 44. AND THE WEIGHT LOSS?!?!? Wow! I have been taking Byetta for about 9 months and lost 50 pounds -- I have a total weight loss for the last year of 67 pounds. Would I recommend Byetta? Without a doubt. F 44 9 months
4/5/2009
 5  Type II Diabetic The nausea is bad. I didn't have any problems with the 5mg but the 10mg is rough. I am going to try to hang in there because my appetite is gone. I haven't lost a lot of weight yet, but I'm only a month into it. I am also having problems with my sugars dropping about two hours after the evening dose. Morning are OK, but night time I fall quick. Any one else have this problem? F 53 1 months
3/29/2009
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 4  Type 2 Diabetes So far after 2 years none of the side effects anyone else has experienced. I am having injection site reaction. Red hives - about 1 inch in diameter at every injection site. They go away in about a week. Is this a precursor to something else? Did anyone else have injection site problems? I did not lose weight on this drug. Did great with blood sugar control for first couple of years but now it is slowly creeping up. I am allergic to metformin and glyburides. They give me GERD and pancreatitis. I know my primary problem is I need to lose weight but we all know how hard that is. F 57 2 years
3/28/2009
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 4  Type II Nausea, vomiting, leg cramps, restless leg, gas, diahrea This is my second time around with Byetta. The severe nausea and vomiting got to me the first time, and I was on the 10 pen. This time I'm back to the 5 pen and it seems somewhat better. Still have some nausea, but not as violent. My appetite is gone which is a wonderful thing. The weightloss is almost worth being sick. I will continue with the 5 pen, but in a month my doctor wants me to go back to the 10. I'm not crazy about the idea, but I will give it a try. My BG is pretty good right now and have lost 5 pounds in 7 days. I have to force myself to drink water because I'm never thirsty. Not good. Overall, I have to recommend Byetta, it's helped a lot bringing my out of controll sugar level down to a manageable number. Has anyone else experienced restless leg syndrome from Byetta? F 55 7 days
3/21/2009
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 4  Type 2 Nausea, constipation, lots of gas, hard to expel This drug has helped several people I know lose a lot of weight, just hope the side effects get better in time. Their AlC numbers have greatly improved, and blood sugar readings. F 46 18 days
3/18/2009
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 2  insulin-dependent diabetes mellitus constipation, flatulence, bloating, 20 pound weight gain Since starting Byetta, I have ALWAYS felt uncomfortable. I stopped the Byetta two days ago and already feel better; I felt like someone was pumping air into my abdomen and even my slacks and bra felt tight on my abdomen, not to mention the 20 pound weight gain since December 9 (today is March 3)! I was also on Lantus insulin AM/PM and Novolog with meals along with the Byetta and 1500 mg of metformin in PM. No benefits from Byetta for me; I am VERY disappointed. I don't see anyone else who complains of weight gain. I'd rather be dead than gain more weight. F 59 4 months
3/3/2009
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 4  type II nautiousness, chills, sleepiness, vomiting This is my 2nd post but wanted to say PEPPERMINT helps with the nautiousness. Can be anything peppermint, chewing gum, sugarfree candy, sugarfree peppermint taffy. It all works. Try it! F 48 2 months
2/17/2009
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 4  Diabetes II Diarrhea, acid reflux, gases, headaches. I have been on Byetta for a year now. I started with the 5 mg for the 1st 2 months and then was upped to the 10 mg. Although I've never really had nausea from it, I still get the diarrhea, headaches and last night, while sleeping, I had a very scarry incident of acid reflux that woke me up and burned like hell for about 1/2 hour. Later that night I had diarrhea. I have lost about 20 lbs (FROM 160 TO 139) since I started without any real effort on my part ( I hate to excersise and only do it sporadically). Byetta has reduced my crazy hunger attacks and now I can wait for regular meal times. My blood sugar levels have dropped and are often in the normal range since my doctor took me off Avandia & Glypiside. I stopped taking it for about a month in Octber due to the high cost of the drug, but my sugars started to rise again. Besides the Byetta 10, I now take metformin 1000 mg twice a day, with breakfast & dinner & glyburide 100mg before bedtime to combat the "dawn eff F 65 12 months
2/14/2009
 4  type II diabetes nausiousness, vomiting, chills, itching, sleepiness Have to go to bed early..very tired and sleepy. I do best with the 5's and an oral medication. 10's make me deathly sick even far after the first "getting use to it" month. Helps my A1C a lot. Food just doesnt taste the same..full all the time. Losing zero weight. On and off the medication twice now. Fearful of pancreatitis but doctor says it's mainly happening in people who have high triglicerite tests. Not sure sometimes if evening vomiting is a side effect or if I should be concerned about the pancreatitis. Usually severe abdom. pain goes with the pancreatitis though, and I have none of that. Medicine worth the effort although inconvenient at times. F 48
2/5/2009
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 5  stopped producing Insulin Servre nausea, chills, fatigue, complete loss of appetite, I get sick if I wait to long to eat after taking Byetta. I try to eat within 30 minutes and I feel okay. Had some bad days of diarehha but I have found that my side effects seem to be every other day instead of all the time after the first week. In 5 months I couldn't get my daily numbers below 300 when testing, in 2 weeks my average is around 125, lost 6 pounds the first week and I;m still losing. I don't mind the side effects because I know it will eventually go away and my results are great so far. I don't feel like eating and when I do I don't over eat. This drug is great. M 37 2 weeks
2/3/2009
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 5  diabetes II slight nausea if i don't eat something in about 20 mins. hair thinning, weightloss Start byetta 5 twice a day june 10,2008 Lost 15 lbs. In 3 weeks and still holding (amazing) 6.4 to 5.3 in 5 mos. Hair thinning rapidly Look and feel great. Stronger workouts are easier now. Was on 2 1000 mg metformin now take only 1 at night Morning readdings were always a problem before now ok Replaced prandin 1 mg 4 times a day. Reason for switch was pin hives and itch. Still chasing that problem,but now they go away for 3 weeks And reappear for about a week - a lot better than before M 69 8 months
1/4/2009
 5  Type II diabetes Slight nausea at the beginning of treatment, some constipation I have lost 20 lbs; my blood pressure is MUCh lower and I have practically no appetite. It's much easier to resist those "bad" foods we all love because I just don't seem to want them at all. I take it with 500mg. metformin twice a day. This is a great medication; stay with it and your results should also show a great improvement. F 60 18 months
12/29/2008
 4  Type 2 diabetes nausea if do not eat something within 20 minutes...AND if I ride in a car within an hour...feel close to vomiting because of dizziness while moving. Haven't lost weight, or appetite, but blood sugars are quite a bit lower. Initially had bruising at injection site, but wellness nurse suggested only using right hand, which is more steady. No more bruising...amazing! F 52 10 months
12/22/2008
 5  diabetes lost 30 lbs, A1C from 7.4 to 6.5, mild nausea in the AM M 61 1.5 days
12/15/2008
 5  DMII - On the plus side - loss of appetite and loss of desire for 'bad' foods, lost about 40+ lbs and reached my bmi, bg and weight goals - On the negative side-nausea, vomiting, chills, fatigue, hair quality changes - which actually increased as I reached my goal weight and glucose control goals. Vomiting and nausea became so debilitating that I had to stop (2 months ago), now weight and bg#'s are going back up again. I was taking 10mcg for almost 20 months - I'm cutting back to 5mcg now to see if that will bring my diabetes back under control without the negative effects. This was the first medication I have taken (in 10 years of diabetesII) that really brought things under control - however as I reached my goals, the negative side effects all increased -it seemed to be too strong - I'm going to cut back to the 5mcg pen - I really hope it works F 57 22 months
12/14/2008
 3  Type II Diabetes Nausea, some initial vomiting that subsided. Fatigue, diarrhea and no weight loss after 2 years. However I have been experiencing extreme allergy symptoms after having no allergies or reactions throughout my entire adult life. Has anyone else have an allergy onset after starting Byetta? M 64 2 years
12/14/2008
 4  Type 2 Diabetes Horrible heartburn, almost to the painful point. Extreme Nausea and now the runs. I have only been on the medicine for a little over a week, but I have already realized that I have a small window when it is okay to eat. If I miss it...then I pay for it. So far though, I am noticing a difference. I look forward to see what the future holds. F 32 1 weeks
12/8/2008
 3  A1C has gone up Wondered if anyone else was getting headaches? I have only been taking it for one week but my head hurts alot. Feel sick to my stomach and less hungry for sure. I guess thats all good, I had previously lost 100 lbs and hope it helps me go down even more. I take it with Metformin 500mg 2x a day. F 46 7 days
12/1/2008
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 3  Type II Extremely cold and nausea about 1 1/2 hours after taking - but only in the evening - seem to have no problem with it in the morning. Fasting sugars are still ranging 272-329. Doctor has now added Glipizide ER 10 mg and Lantus 15mg in the evening. Have lost NO weight - even with watching diet. F 39 5 months
11/25/2008

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