VAGIFEM Reviews (ESTRADIOL)

Average Rating: 2.4 (300 Ratings)

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 Type: Rx Drug

  

VAGIFEM  (ESTRADIOL):  This medication is a female hormone (estrogen). It is used by women to help reduce vaginal symptoms of menopause (such as vaginal dryness/burning/itching). These symptoms are caused by the body making less estrogen. When treating only vaginal symptoms of menopause, products applied directly inside the vagina (such as this medication) should be used first. Estrogens that are taken by mouth, absorbed through the skin, or injected may have greater risks of side effects due to more estrogen being absorbed.   FDA Approval Date: 1999-03-26 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15


RATING  REASONSIDE EFFECTS FOR VAGIFEMCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Vaginal dryness & constant UT1's I felt immediate relief from burning etc,and have followed 2 week every day, then twice a week up to now . I felt immediate relief from burning etc,and have followed 2 week every day, then twice a week up to now ..However I have noticed breast pain for a few weeks & I suffered very badly with this all through my menstruating years & don't want to have this again in life! Also I'm a very thin person and have been all my life, I haven't changed my diet or fitness routine, but have gained a few pounds! I do feel 'not quite myself!' in a strange way ...so I'm going to try to have a 10mg pessary once a week ..Would appreciate any feed back if others have done the same. As feeling 'not quite myself!' is a better than the misery of UTI's etc!.. So this is my 'move' rather than stop Vagifem F 60 14 days
10mg 2X W
8/14/2020
Email
 1  Menopause. VA, irritation, itching. Anxiety, depression, fatigue, breathlessness, feeling out of sorts. I don't do any medications, not even pain killers. I know my body and mental state extremely well. From the first time I took it, I started feeling very anxious, out of breath, and started feeling depression. I thought it was in mind or too sensitive to this product. Found this site by coincidence and glad I did. I'm not alone. I see women with the same exact reaction. I'm getting off it today and will look for another alternative. F 58 0 days
10mg 1X day
8/9/2020
 1  Vaginal atrophy. Regular UTIs Severe fatigue. Feeling nauseous. Pins and needles in hand, arm and feet. Low mood. Palpitations. Weight gain. Headaches. Severe lethargy. Shame about these side effects as soreness is better as is the frequency of getting UTIs. BUT after feeling SO ill with the side effects I cannot possibly consider continuing with this drug. So its back to the drawing board. Agree with many women on here.....this drug MUST be getting into the blood stream!! Otherwise why these symptoms? Its OK my GP saying no it doesn't...I know my body well enough to know that my symptoms are due to this drug! Recent ECG and thorough blood tests have ruled out thyroid, vit b12 defiency etc so no other reason for me feeling so dire. I only hope it gets out of my bloodstream asap and I can get back to feeling normal again. I'd rather have a UTI than feel this way. F 59 0 months
10mg 1X AN
8/8/2020
 3  VA bad burning The day after insertion burning off and on Been taking it for 8 weeks It seems to be getting better after insertion a small bit of cramping occasionally I'm optimistic F 69 2 months
10mg 2X W
8/6/2020
 2  Vaginal atrophy/ repeated UTI Diarrhea, dizziness, increased blood pressure , back pain , abdominal cramps . And now my fibroids have come back even though I am 4 years post menopause ! Had none of this before starting Vagifem . Also hot flushes. I was experiencing frequent UTI,S so doc prescribed vagifem . Also had some atrophy . Started Vagifem and noticed initially that I was getting some hot flushes. After the initial 2 week induction I started experiencing explosive Diarrhea and abdominal cramps . Saw a gynaecologist and had an ultrasound.....I have a 51mm fibroid ! I had fibroids in peri but after menopause they shrunk and were on thier way out . I have since read the medical side effects of Vagifem and it can cause the fast growth of fibroids .......not what I wanted to experience again ! I am gutted , because my UTI’s have gone and atrophy does seem better . But I cannot continue when it causes fibroid growth . Also seems very odd to me that if this product does not get absorbed into the body , how I could have suddenly developed all these other issues like Diarrhea and increased blood pressure . Some very strict research needs to be undertaken into this product . F 60 8 weeks
10mg 2X W
8/6/2020
 1  Uti and painful intercourse I was bloated ,headaches and very low mood forgetful too. It helped for a bit with intercourse but the low moods and bloating together with headaches persisted. Going back to GO to see if I can have daily low dose of antibiotic to avoid uti. My mood is back to how it was having come off vagifem Side effects outweigh the positives F 57 10 months
1X W
8/6/2020
 5  V A pain. Itching UTI Migraine and bloating for the first two weeks I am fed up reading negative reviews. I have been in terrible pain for 6 months with an on going UTI all due to V A. My doctor has been amazing and said it was V A due to perimenopause. I am taking Vagifem which has ceased nearly all the pain and is also helping with the UTI. This is A wonder drug. Stop leaving negative reviews when some of you tried it for 2 weeks and gave up. It does cause migraine bloating until your body gets used to it. For ladies who are really suffering please try vagifem and do not give up till you have taken it for 12 weeks. F 49 56 days
10mg 2X W
8/4/2020
Email
 1  Vaginal Atrophy( itching/menopause Nausea, vomiting, weight gain, bloating, shortness of breath, sore throat, extreme anxiety and depression I took my 1st dose and had rapid relief. 2nd dose and a few hours later had vomiting and continued nausea throughout next day. Day after had shortness of breath, bloating and anxiety. Felt a little better 3rd day but did not put my symptoms down to the Vagifem so took my 3rd dose. Following day felt very anxious also depressed at the weight gain of 3kg. Next day decided to reread side effects and was like tic tic tic... I had many but the most serious was the mood and depression ( which I never have experienced) I rang my GP back who was surprised but told me to stop taking nonetheless. The dark mood passed after 3days The shortness of breath/asthma took several days to subside. I would definitely think twice before taking but just make sure you are well aware of the side effects because they can come on strong and fast. Something I have never experienced with any other medication I have taken in the past. I currently take Estrogel & Mirena for my HRT and no issues at all! F 51 7 days
10mg 2X W
7/31/2020
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 3  Bleeding after sex Feeling bloated and weight gain. I feel they did help but hated the weight gain,also got more migraines while taking Vagifem. F 60 27 days
10 1X day
7/22/2020
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 1  Vaginal Atrophy Dizziness, nausea, pain in chest on 3 days. Just not feeling well. F 54 7 days
10mcg 1X day
7/21/2020
 5  Vulvodynia I get loose bowels but not so bad that it bothers me. This product has CHANGED my life. I have had YEARS of UTI problems and just over the last 18 months dreadful vaginal pain which was diagnosed as Vulvodynia last summer. For the first time in YEARS I have no vaginal or bladder discomfort which has taken over and ruined my life for years. I always knew that one day I would be thrown a lifeline I just had to wait for that Eureka moment. I have loads of energy now where as before I used to get in from work each day and sleep. I have started running and walking daily. Overall I cannot rate this product highly enough it has changed my life!!!! F 49 45 days
10mg 2X W
7/17/2020
Email
 1  Itching Dizzy insomnia Anxiety and not feeling myself at all Would not use again second time used Longer last time And same effects Hoping gets out of system quickly F 55 8 days
10 1X day
7/17/2020
 1  Painful sex fatigue, feeling very unwell , flu like symptoms,nausea , breathlessness, sweating, headaches After reading previous comments from other contributors, have stopped taking Vagifem and have started to feel better. F 58 4 days
10 1X day
7/16/2020
 2  Dryness/Urinal problems Burning on days I take it. Headaches. Anxiety and crying spells. Doubtful it is working but will persevere and see if things improve. F 50 1 months
10mg 2X W
7/15/2020
 1  Bladder infections blood in urine F 53 7 days
10mg 1X day
7/8/2020
 3  Bladder sensitivity and vaginal dry I was reccomended to try this due to having bladder symptoms eg low ache, needing to pee, plus got mild thrush sometimes. Had been using vagisan from chemist for vaginal dryness, which I liked. I did not want to use Vagifem but was told the hormone would help these symptoms I bloated and I'm sure a put a few pound on in 3 weeks.... doctor did nt think it was Vagifem though. I had lower back ache, on and off, Was tearful, sore throat and had severe chest pain for 10 mins on the 4 day of starting the pessary. I thought it was a panic attack, but I'd never had anything like that before. Reading the other ladies comments, I think these symptoms were connected. I had decided to come off it this week and my doctor suggested to just do one a week. Now I ve read all this, I'm staying off it. F 53 1 months
10mg
7/2/2020
 2  VA Backache,nausea,reflux,anxiety,shooting pains in pubic area I'm stopping this just under the 2 weeks daily dose,my lower back has been sore since starting it,nausea after eating,constant reflux,which I'm never bothered with and anxiety,too much to put up with,so back to the drawing board F 56 2 weeks
10mg 1X day
6/24/2020
Email
 1  Recurrent UTIs after hysterectomy I am taking topical estrogen on my legs too and have never had side effects. Tried this and felt moody, shattered, dizzy, very poor concentration. It was like I had a bad bout of flu. Will never use again. All symptoms started day after first dose. A terrible medication. Don't use 48 3 days
Lowest
6/4/2020
 1  Vaginal atrophy after menopause I had practically all the side effects listed: bloating, cramps, headaches, vaginal discharge and bleeding, weight gain, and swollen and painful breasts. I feel the message being relayed by doctors about this drug is deceptive and misleading. I was told that there were no systemic effects and that the estrogen remained locally, which is absolutely false. The vaginal bleeding is the most worrying side effect, since I had a pap smear and ultrasound shortly before starting this drug and was given the all-clear. I now have to be tested again and am afraid the estradiol may have caused a buildup of the uterine lining or even worse. Please be aware of all the risks and use with caution. 56 6 weeks
6/3/2020
 1  Vaginal atrophy Heart racing, increased anxiety, sleepless nights, stomach cramps, nausea, diarrhea, headaches, vaginal burning. Doctor told me to stop taking med and if symptoms persist to test for COVID. The side effects described happened within hours of taking the med and persisted for days. F 66 2 days
5/22/2020

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