ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  PTSD witnessed Awful Event. Anxiety Am not very happy taking Meds and so have a low tolerance to most drugs even a basic Pain med but felt highly Anxious and wired all the time so Dr Recommend it . From Day one take at night, I feel hungry all the time the next afternoon . Usually eat normally Lunch and Dinner, all cooked at home..I feel extremely hungry have eaten alot more than usual, trying to make that salad and fruit, weigh 59 kg at the moment, am conscious of the other reviews of weight gain. Don't feel any better mentally yet but I will give it a go for a few weeks. F 55 4 days
2.5mg day 1X day
11/16/2023
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 3  Schizophrenia Increase in tremor, confusion Calming effect F 58 15 days
5mg
1/13/2020
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 2  Schizophrenia Bruxism Experience major teeth clenching. Cracked my teeth. F 37 3 years
10 1X day
12/18/2018
 2  Anorexia, PTSD, Depression Gained 50 pounds in less than 6 months. Even on 2.5. Was pregnant too, but still. No way did I eat enough to gain that amount of weight. But if it saved my baby it was worth it. Just bad situation all around with anorexia and pregnancy. I wish I was given all the info about it. Like extreme weight gain with small amounts of the drug. F 29 6 months
2.5 1X day
5/14/2011
 2  schizoaffective bipolar type Tired, sleep 14 hours a day, loss of creativity, dulled intellect, lazy, slight weight gain I really miss my creativity and I feel less spiritual. My hallucinations and delusions are gone, but I miss those, too. F 27 6 months
10mg 1X day
6/12/2011
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 2  psychosis Racing heart, shakes, sleeplessness, weight gain Did not wish to take this drug but it was forced on me after 2 days in Mental Health Unit. As I would not agree to take orally it was forced on me by injection - I had discussed with the Doctor on being admitted to the unit that I did not wish to take any medication - it was offered to me to help claim me. I was hearing some voices at the time but was not in a distressed state or likely to harm myself or anyone else around but the Nurses told me I had to take it - this being on the Sunday night when there was no Doctor to discuss it with. I was then given it orally for the next 8 days and advised the nurses of the side effects I was feeling on at least 3 occassions - still without having my blood pressure taken or seeing a Doctor during this whole time. I then had a weekend out of the unit and decided I would no longer take it. Upon returning to the unit I advised that I had stopped and no further action was taken. I am appalled that this drug was give to me when no actual diagnosis had been made of my condition (first ever episode at age 44) and upon being discharged from Mental Health they still could not give me a diagnosis. It did not decrease any of my symptoms however over the next 3 weeks they disappeared on there own. While this drug may have it's benefits in some cases does there not need to be more done to identify the issue before administering a drug that can cause numerous side effects - or is it just easier to try to sedate people because people with Mental F 44 8 days
5-10mg 2X day
2/10/2011
 2  Bipolar 1 Massive weight gain (40 lbs), laziness, flattened affect (didn't even cry after a close friend jumped off a building to his death) Try Lithium first. It is the gold standard for bipolar. The pharmaceutical companies are marketing these atypical antipsychotics for mania and, while these drugs do help, they overmedicate. My personality became flat and I felt removed from my coworkers, who experienced a regular range of emotion. That may sound good, but it makes you stand out like an oddball. Also, some doctors don't have to monitor with blood work the atypicals the way they must with Lithium. Lithium has been much more labor-intensive for my doctor, but switching to it was the right call -- a call I fortunately insisted upon. Zyprexa had made me so fat and lazy, my partner finally called me out on it and said, "It's unattractive!" I've already lost 20 lbs in two months since going off of Zyprexa. My appetite has been cut in half. F 33 1 years
10 mg 1X day
3/3/2011
 2  manic depression psychosis with hallucinations. Ended up in the psych ward until it wore off. My family still laughs at the stuff I did when hallucinating. F 39 10 days
1X day
8/2/2011
 2  Schizoaffective w/ Bipolar Subtype Weight Gain This drug helped me get back on track as far as being more social, hygenic, and less paranoid. The downside....45lbs weight gain in two months. F 35 2 months
30mg 1X day
1/7/2012
 2  Mental Swollen feet weight gain.. Can't sleep & shortness of breathe.. F 40 10 days
20
2/22/2012
 2  depression Initially assisted with sleep but after 2 weeks that has subsided. Dry mouth and feeling 'fuzzy' for the first week or so which made it difficult to work. But it did settle my depression (in conjunction with continued but slightly increased zoloft medication) & I have felt much more stable. BUT weight gain has been awful - with a history of eating disorders & food/weight "issues" my entire life, I cannot STAND that I have gained so much weight this past month of taking this drug. The weight gain for me is NOT worth the feeling of being more stable. I'd rather be low and not overweight than happy and overweight. F 33 1 months
1/13/2006
 2  Schizoprenia - psychotic episodes overall dullness, weight gain, zombie like reactions, sadness, lost all feeling of hope for the future. became less creative. too afraid to stop taking it. F 33 2 months
11/12/2006
 2  depression This medication has made me feel so sleepy during the day, as was directed by my doctor to take it before bed at night, I have only taken it twice, and both mornings I woke up late with the alarm clock blaring into my ears. I slept way too hard on this medication so far and have been extremely hungry and thirsty. I'm not sure if this is the right medication for me. I see my doctor tomorrow and will tell him of the side effects. F 28 2 days
10/5/2005
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 2  acute psychotic episode weight gain (20 lbs) fatigue flattened emotions, slight depression and loss of wits severe withdrawal symptoms (including muscle twitches, nausea, vomiting, sensitivity to light and sound). Withdrawals lasted 2-3 months. Terrible physical withdrawal symptoms when you try to get off it (no craving though). Chemical description of zyprexa (olanzapine): 2-methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine. Benzodiazepine! In any case, withdrawals last for months. And no- vomiting 24/7 has nothing to do with the original illness coming back. Read up on supersensitivity psychosis on the internet. People who took zyprexa for other reasons than psychosis (i.e. depression), and never had a psychotic episode in their lives, reported that they got psychotic symptoms induced by this medication after withdrawing! Also, there are many cases of diabetes and tardive dyskenisia linked to this drug. If you're not on it, try a safer alternative. If you want to go off it, taper slow (cut pills into halves). F 31 8 months
7/13/2005
 2  Schizophrenia Tremendous weight gain, tiredness. Hope you have nothing better to do than sleep all the time, because zyprexa might make you feel pretty tired. I also gained 40 lbs in three months. F 29 1 years
8/13/2005
 2  Bipolar daily drowsiness, extreme fatigue, lack of concentration, feeling spaced out most days. I've been on Zyprexa for a few months now and have gained around 20 pounds, feel like sleeping ot eating most of the day. I started taking it on my second episode of mania but it still did not prevent me from the depression that came afterwards. I went to the doctor to complain many times and we even reduced from 10 to 5 to 2.5mg with another mood stabilizer (Topamax), but i still feel really sleepy and food obsessed! But i'm afraid of getting off the drugs completely and of risking another psycotic episode. F 25 4 months
2/18/2006
 2  Bipolar Sleepy, Could hardly stand up, food cravings, weight gain Helped with sucidial thoughts. Only was able to take for a few weeks. F 44 3 weeks
3/1/2006
 2  depression, insomnia dry mouth, increased appetite, extreme weight-gain I took Zyprexa for a week, and it was so wonderful to get a regular sleeping pattern for that short time. However, even though I was warned about the increased appetite I might experience, I was very careful to stick to my weight-loss programme - only to find that I had gained TEN pounds in the 7 days I was taking the drug. I came off it immediately and worked hard to lose the weight - I got rid of it in about 3-4 weeks because I think some of it was fluid retention. Stopped taking it because it wasn't worth the weight-gain, but in hindsight I also felt that I was getting a kind of false-sleep - it was more like a coma than refreshing REM sleep. If at all possible, I prefer to sleep naturally now (having had a psychotic episode from other sleeping pills) even though it's much less reliable. F 25 7 days
9/18/2004
 2  psychotic depression extreme fatigue during the day even if i took it at night, craving nothing but fattening sweets I was so sleepy during the day that I would sit down somewhere and immediately fall asleep with my mouth open and drool all over myself. Seroquel is better for helping me sleep; it doesn't cause that daytime drowsiness. F 21 2 months
12/10/2003
 2  bi-polar disorder weight gain, 25lbs in 3 months and still gaining seems to work well with the manic stage of bi-polar disorder but because of the weight gain, I do not recommend it. F 39 3 months
2/11/2003

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