ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender males first.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Extreme Anxiety, Bipolar II Hunger - haven't taken it long enough to notice a weight gain but I'll bet it's happening. I had anxiety that was off the charts, had even been hospitalized for it, and taking 4 meds and still had the high anxiety. Within 2 hours of taking my first 5 mgs and then another 5 mgs an hour later, my anxiety went from a 10 to a 4 on my scale. It's a wonder drug. Too bad it causes weight gain. I and my dr are going to try to get me off of it as soon as possible; maybe using it only as a rescue drug. F 52 7 days
4/28/2008
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 3  Mild Psychosis 2.5 mg , Weight Gain - 4lbs within 21 days Slite Moodiness: Anger, Sadness, Frustration Did end my paranoia and self conscious behavior the slite anger, moodiness and depression is something that at this point I can handle better I think because of this medication. Not happy about the weight gain. I find that if I excercise daily (atleast 20 min) I excercised everyday last week and lost a 1lb. F 30 28 days
4/8/2008
 3  Depression + anxiety Nada; friend experienced major weight gain leading to diabetes My psychiatrist put me on this for a week, dose 2.5, in addition to 225 Effexor on the theory that it could boost me out of my depression. It helped, but it wasn't amazing; on the other hand the appetite didn't kick in. A close friend with manic depression was on it for several months and had a lot of weight gain, to the point that she had joint problems and early diabetes. She said it was great mentally but the price was too high (She's 51, by the way). F 20 1 weeks
4/28/2008
 3  reduce side effects of other meds Started zyprexa to assist changing from one type of anti depressant to another with long medication free period required to get first drug out of my system. have been unable to cease Zyprexa. Side effects large weight gain 50+ lbs even on low doses 2.5-5mg and excessive sleep at moment need 12-14 hrs, difficult if you have to work. Still feel tired all day despite all that sleep. Have developed diabetes type 2, high blood pressure, high cholestrol, fatty liver gastric problems from the weight gain. Just feel FAT and bloated and uncomfortable. Each time I try to reduce or cease Zyprexa I seem to get ill all over again. This drug did what it was supposed to but the side effects are overwhelming and it is difficult to get off it. F 40 3 years
1/7/2008
 3  Bipolar The only side effect I've noticed is a constant hunger and gas F 34 12 days
12/13/2007
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 3  psychosis weight gain-forgetfulnes-not as alert-tired with all of zyprexa's side effects...........I would rather have them(side effects) and not have psychotic episodes which Zyprexa helps.. than not take Zyprexa-and have no side effects but have episodes.........to me it is more important to be in sane state F 21 5 years
1/31/2008
 3  bipolar disorder sleeping too much, weight gain zyprexa helped do its job... I didn't have my highs and lows like before and become more consistently productive at work. I've stopped the drug and will never go on it again, though, because i gained SO much weight. It made me hungry all of the time, even after just eating a full dinner. I gained 30 lbs... went from size 2-4 to a size 8-10. i'm going to try another drug now... hoping for topomax-- a mood stabilizer that helps you lose the wt that your other mood stabilizers packed on. we'll see if the doc agrees :) F 28 1 years
1/24/2008
 3  rapid cycling, anxiety, anorexia insomnia, NO weight gain or increase appetite, feel jittery/shaky I am so disappointed this med has not increased my appetite or helped me sleep. I just lie in bed, feeling like I am going to sleep, but I can't drop off...It's torture. I also feel jittery or tenseness in my muscles. It feels like anxiety so I take 2.5 more, no differnence so i take less...and feel anxious and shaky like I need more. I m so confused! I do take seroquel 400 mgs, I wonder if they are interacting with each other? I am trying to like this med, but i need to sleep and to gain weight......I don't know why I have opposite to the traditional reactions. I am so frustrated. But I am not going to quit yet. F 42 14 days
2/4/2008
 3  bi polar, anxiety, insomnia At first I loved this drug because I was able to sleep. However after I had a seven day long panic attack, during which I tried taking Zyprexa to help overcome it, I was left unaffected. I was hospitalized and my dosage was increased from 5mg-10mg "As Needed for Sleep" to 20mg every night. I experienced sudden weight gain and as of yesterday stopped taking it altogether. Yes it helps you sleep. Yes it helps with MILD anxiety. Yes it helps you gain weight rapidly. I refuse to stay on a medication that makes me gain weight. I'd rather have insomnia. However I am hoping to speak to my doctor soon about getting on Topamax or something else instead. F 23 3 months
8/4/2007
 3  counteract SSRI-induced mania fatigue, increased appetite I was prescribed this to calm down from prozac-induced mania. It worked well but started to make me eat too much so I stopped taking it. F 17 3 weeks
5/20/2007
 3  Postnatal psychotic depression weight gain/drowsiness. craving sweets. I looked pregnant it all went on my stomache. I did manage to give it up. It was hard for me even though I am a health freak + never had an addiction. It took 4 months to go from 2.5 to 0. Then I stopped taking the little slither and had bad withdrawal with a crisis day at day 14. Then I got better from there and by 4 weeks felt great started sleeping fine, back to myself. I nearly went back on (at 14 days) but my excellent psychiatrist said 'No the ilness is over you dont need it' She prescribed something for sleep which I ended up not taking. I did recover, I am happy about that. F 42 2.5 years
6/8/2007
 3  depression sleepiness within 1/2 hour of taking it; weight gain of 10 lbs. despite no changes in eating habits and a new exercise program F 31 3 months
2/17/2005
 3  depression a little sleepiness,but I was some tired by hunger So I started looking for a reason of my depression and broke off taking zyprexa,talked on a reason of depression with my mother,burst into sobs for a few hours and I don't have a depression more,and not taking zyprexa too.Now I am happy F 25 7 months
2/28/2007
 3  Bipolar I Extreme Weight Gain; Fatigue; Constant hunger (esp. cravings for carbs/bread/pasta. Originally on just zyprexa, weighed 100-110 pounds (within the healthy range for my height/gender). Within 4 months shot up to 160 pounds. Immediate diabetic symptoms (though tests were negative). Topamax added at 100mg, hunger and cravings for carbs died immediately. Further exercise and counting calories / south beach style diet brought weight down to 115-120 range. Hate the drug, but it works AMAZING for its purpose. With lithium now too, no bipolar symptoms. 100% normal life, so you'd think, though I need at least 8 hours of sleep...preferably 10. F 23 6 years
10/4/2008
 3  depression/severe anger/mood swings sleep walking, sleep talking, intense hunger, weight gain i took zyprexa for 2 weeks. i felt WONDERFUL!! but, i had to take zyprexa at night and i don't ever remember actually sleeping. i woke up really disoriented and was told i was walking around appearing to be awake. this drug also makes you really really hungry, all the time. i gained 5 pounds in 2 weeks. made me feel great but side effects were too intense. F 25 2 weeks
3/19/2007
 3  Bipolar Disorder Weight gain and constant hunger. I gained about 40 pounds and just could not stop eating. Also felt very boring and flat...no personality at all. I just stopped a few days ago and already my appetite is back to its normal level and I feel better. The Zyprexa definitely helped with my racing thoughts but the side effects are just too awful. I have problems with depression and nothing depresses me more than being fat. F 58 365 days
8/1/2006
 3  depression weight gain, psoriasis, fatigue, trouble breathing This medicine works very well for acute or severe depression. Out of more than a dozen meds that I have tried it is the only med that signifigantly improved my debilitating depression. However the side effects are really terrible. Specifically the weight gain. If you have ever had a problem with psoriasis this is not the drug for you. F 34 4 months
7/24/2005
 3  manic depression -inability to feel sexual -totally blank mind -mood-less. no downs and no ups. -flattened creativity -inability to be in love -don't feel like exercising ever, even though that used to be one of life's great joys -hungry all the time. hungry for food, but not sex, nor anything else. -woke up and ate in sleep at high doses -don't get insights, or bubble with ideas, as before -weight gain. stopped it, still seem to be gaining although am not hungry or overeating anymore. -sleep 12hrs a night. blank dreamless sleep. wastes a life. -very very balanced. never upset, never critical, never angry --even when it's appropriate. --stagnating. a wonder drug for stopping a manic episode (for me, it knocks out mania in 1-2 days), but a crummy ongoing stabilizer. it obliterates many of the reasons to be alive, such as feeling alive. BESIDES, I believe God does speak to me and through me and I don't like being flaming manic but I don't like shutting off my channel completely. I feel numb, like I've been brainwashed, and don't have the insights I would otherwise have--on a regular day, at MY baseline. No, specialists and drs, MY baseline is NOT on Zyprexa. there is more to life than eating and sleeping. A LOT. I do intend to keep zyprexa in my drug cabinet for when I might ever need it. I sometimes wonder though if Haldol would be better. doesn't work as fast, but less ongoing problems. F 39 2 years
12/18/2006
 3  depression, borderline PD To be on a medication so long it was hard to tell what was me and what was the medication when I went off it I realized the sleepiness and laziness were side effects. Also I had weight gain, high cholesterol, high triglycerides, and high glucose. Heat intolerance which made me sick when I ran 5K races on warm days. Withdrawal: increased anxiety, muscle tension, heightened sensitivity to stimuli, aggitation. These mimiced the symptoms I went on the medication for. But the withdrawal was complete in two weeks. Now I am very glad I am off of it. Zyprexa is a mixed blessing. When my life was unstable and my depression was more severe it was a life saver. It gave me boundaries. When others were upset I didnot have to be upset with them. So I was much less sensitive to perceived rejection. I am fortunate I now have a stable job and my kids have grown up well. So I don't need it to function. When I went off it I did so because of the metabolic side effects. I was surprised to experience the anxiety and tension. And equally surprised when they went away after two weeks. I have discoverd I am not lazy or sleepy or hungry all the time. That was the zyprexa not me. However if my life fell apart by getting fired or someone dying and I became suicidal and unable to function I would probably go back on it F 54 8 years
12/9/2006
 3  depression, anxiety, dissociation 20 pound weight gain, which went down when I stopped taking it; increased blood sugar; did help clarify my thoughts I wish Zyprexa weren't so dangerous with the diabetes and weight gain, because coupled with an antidepressant, it really did work wonders for me. It helped me to clarify my thoughts, and to feel more stable. But to me the side effects and potential long-term health risks aren't worth it. I wouldn't recommend anyone take this drug unless your life (literally) depends on it. Try another of the atypical antipsychotics. I've switched to Abilify, which isn't as helpful, but still works. F 30 2 years
10/13/2007

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