ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  bi-polar disorder Dry mouth, excessive hunger (good thing though, had lost over 30 pounds prior to being put on medication,) decreased fine motor coordination with tremors of hands. Unlike most people, does not cause any drowsiness at all. I continue to experience insomnia. Other antidepressants and most cold medications do the same for me though. I take it now in the a.m. F 49 2 weeks
11/10/2006
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 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 3  bipolar I had a good result in stopping mania but now I am more depressed and having suicidal ideation. F 40
7/6/2005
 3  Bipolar II I feel like a zombie, my personality is dampened. The zyprexa causes me to sleep 16 hours a day. I used the sleep-inducing quality to withdraw from Klonopin, so that was successful but I can't wake up clearly until the late evening. I also take 300 mg. wellbutrin XL and 150 mg. effexor daily. It's disrupted my reading ability. I haven't experienced weight gain but I do feel hungry all the time. I often feel numb, like I'm two steps behind everyone else. If anyone can relate to these symptoms, I'd appreciate a response. I'd like to know if the zyprexa is causing me to think I have brain damage, or if it's something else. F 49 4 weeks
9/16/2006
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 3  Manic episode due to drink spiking Weight gain, constant need to sleep, apathy, low mood, over emotional, irritability, loss of confidence, lactating from breast. I was on Zyprexa because my drink was spiked, which caused a chemical imbalance in my brain, which ultimately resulted in a psychotic break and very frightening manic episode. I experienced symptoms similar to bi-polar. Wherein I couldn't sleep, was paranoid, mood was elevated then suddenly sow, I was happy one minute aggressive the next. Doctors put me on Zyprexa which helped straight away. Within a day or two I started returning to my "normal self" doctors wanted to keep me on zyprexa for a few months to monitor the situation just to rule out bi-polar and make sure it was a one off. During the 7 months I was on the medication my dosage was lowered as I was weaned off. However I experienced some pretty undesirable side affects. My breasts became tender and started to leak! I was constantly tired, did not want to get out of bed, suffered depression was bitter angry etc. I was very lethargic and felt like crying all the time. I also became very anxious, nervous and worried. However my psychiatrist was great and eventually I came off the zyprexa totally. It is still working it's way out of my system but I am losing the weight and am much more outgoing and happy my sleep pattern and appetite have returned to normal. I have experienced an irregularity in my periods however. I went 5months without getting one since I've been off the tablets. I sometimes experience random twitching or sensitivity to stimuli. Overall I felt zyprexa did help in rectifying the situations, bu F 19 6 months
15-10-5 1X day
11/5/2012
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 3  psychosis and mood disorder weight gain very quickly, increased appetite. Increased anxiety and sleepiness I came off olanzapine 3 weeks ago. Feel very odd, strange like. Spaced out withdrawal effects have left me feeling like this. not symptoms of psychosis those were paranoia, and have not returned. Also experienced nausea daily. could do with some advice from anyone who has experienced this weird feeling and how long it lasts for. Its uncomfortable and i would like to wake up. thanks F 22 4 months
11/1/2005
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 3  schizoaffective disorder I've put on 80lbs and developed diabetes . It helped when I was psychotic and I suffer terrible insomnia and other symtoms when I try to come off it. I also get nightmares. And I can't orgasm. Also I can't write or read anymore . I feel lost and bored and I donttake pleasure in anything.I want to come off it but I've tried before and it makes me so completey exhausted I go back on it. F 44 10 years
20 mg
3/16/2013
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 3  schizophrenia weight gain; always hungry; sedation; apathy Helped tremendously w/hallucinations, but made some of the negative symptoms worse -- no emotion, no creativity, flat affect. I have to take it -- nothing else works. But I try everything else that comes out hoping to switch to something that doesn't cause weight gain. F 49 7 years
9/20/2007
 3  bipolar II I have been on zyprexa for a couple of years. I just got my bloodwork back and I have dangerously high cholesterol. We are going to have to try and find something else. The zyprexa did help me with suicidal thoughts F 45 2 years
8/3/2006
 3  Bipolar, Boderline Sleepyness and drowsiness, sleeping at work, acid reflux I am tired but my thougts are not running like crazy. Not enjoying the drowsiness. I am a front line worker and need to act fast. I am not able to think properly and am experiencing the world at about half the normal pace. People talk to me and I feel like I am under water. Can't keep my mind focused and my eyes are slow. F 33 2 days
8/3/2006
 3  Depression & Anxiety Extreme weight gain; out of control appetite! Couldn't get enough to eat. All I thought about was food constantly. Dr. put me on Zyprexa 2.5 mg once per day. I read the reviews about weight gain but didn't think it would happen to me. Thought I would be one of the few exceptions to the rule and I would not experience weight gain. Boy was I wrong! I am a 4'10" woman and I went from 114 lbs to 124 lbs in 2 weeks. My appetite increased until I was out of control. All I could think of was eating. I also have an eating disorder and the weight gain made it worse! However, in all fairness, it is an overall good drug and I really liked it; made me feel calm; helped my anxiety and depression, and helped me sleep, but I couldn't deal with the extreme weight gain. Dr took me off Zyprexa and put me on Abilify. 3rd day off Zyprexa and so far no withdrawal symptoms. This is a good drug if you can deal with the weight gain. It really helped me, but I believe Abilify will be better for me as it doesn't normally cause weight gain. F 57 1 months
2.5 mg 1X day
7/27/2013
 3  Depression Helped, but not worth the side effects of weight gain, acne, groggy all the time, zero libido, no motivation, body aches and pains. My prescribing Dr added Zyprexa to help with a severe withdrawal and agitation incident I had 5 months ago when my pharmacy slipped me generic Tofranil PM instead of the brand name. Zyprexa helped calm the side effects of withdrawal, which were pretty severe. I began experiencing relief within 36 hours. Since that incident, I've decided to try a natural approach to treating depression because I'm fed up with the horrible side effects that medication can cause. I've been able to wean off all other medications with the help of a Naturopathic Physician, but getting off of Zyprexa is proving to be a battle. I experience severe withdrawal symptoms if my dose is lowered too quickly or too much, so I have to abide by a 10% discontinuation schedule (10% reduction of dose every 2 weeks). I gained 30 lbs on this medication, it is messing around with my hormones, I have pretty bad acne, am groggy all the time, have zero libido, no motivation to do things, and now I'm experiencing a lot of body aches and pains. I am thankful for the help Zyprexa provided, but I'm looking forward to being free from this medication. F 32 5 months
2.5 1X day
11/26/2010
 3  Bipolar I Weight gain, hypersomnelence (sleeping 11-12 hours every night), sluggishness I was a champion of Zyprexa when first on this website about 6 months ago: it calmed me, helped me sleep. But as time wore on, I began to find its considerable side effects intolerable. My partner twice mentioned my weight gain and finally called me unattractive and questioned why I would be so commited to a drug that makes me fat and is leading me to diabetes. My doctor diagnosed me as being pre-diabetic (I am 32 years old). I was a person who was always a healthy weight and, with Depakote and later Zyprexa, I gained 70 lbs in a year. Most recently, I finally insisted to my doctor that I go on Lithium and come off the Zyprexa. To my surprise, he told me, "The more I am in practice, the more I am turning back to prescribing Lithium to my bipolar patients." Wish he'd told me that 70 lbs ago! Don't try this drug without trying Lithium first. F 32 12 months
5-10 mgs 1X day
1/12/2011
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 3  Bipolar 1 Huge weight gain, constant hunger mainly carb cravings, sleepiness I absolutely hate this medication. I was taking it for about 3 years and it only had a mild affect on my mood. The Doc then took me off it and I lost 20kgs of the weight I had gained in 3 months. I then had a manic episode and he once again prescribed Zyprexa at a lower dose. While I haven't regained the weight I have stopped losing (I still have lots to lose from gaining while on Zyprexa in the first place) F 55 3 years
7.5 mg 2X day
9/15/2011
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 3  ptsd,bipolar2,halluc,parinoia,anexi Very tired thirsty inability to take care of kids alter driving stay hunger At time this meds can be very good for me when I am taking correctly however it takes awhile to get in my system I'm tiny I don't mind the weight as I can use it however I don't want sleep for days nor feel fatigued and very thirsty in the fine print are the warnings of issues on meds leaflets I need to no what to do to keep from sleeping for days but you should not stop them once started as my condition worsen each time I'm experiencing withdrawls from being off meds but I don't want the meds to kill me either F 22 2 years
10 1X day
8/22/2011
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 3  Bi-Polar- Borderline Personality As of yet, I have noticed any side effects. HOWEVER- my husband says that yes I am not crying anymore, I am very aggressive! Meds I am taking-Zyprexa- 2.5 Lamictal -300 mgs Klonopin-0.5 All low doses- I have not gained any weight, fact I have lost weight. Zaprexa does make me VERY thirsty- dry mouth- and constipation. Lamictal- makes me sweat profusely and vivid dreams. F 42 30 days
2.5 1X day
9/4/2011
 3  Severe Depression ferocious appetite and severe fatigue, night sweats and crazy dreams. This drug wasn't too bad, it did what it was supposed to do and made me much less obsessive and emotional, however the side effects outweighed the benefits. I was hungry ALL THE TIME and was always eating, I gained weight in a matter of days. It also makes you want to sleep for hours and hours, I actually have some of this medication saved for when my insomnia kicks in and I need to get extra sleep. My doctor tried lowering the dose and it did reduce the severity of the side effects but it still was not worth taking because they were still too much for me to cope with. F 25 5 days
5 1X day
3/5/2010
 3  Bipolar disorder/mania Vegetable-like state, weight gain I was put on this drug (was traveling in Argentina and it was first choice of doctors w/o consultation) after a psychotic attack and it drastically reduced the mania. It took a few days to work (I believe I started at 10 mg for 2 days then 20 or 30 mgs for the rest of the duration). I was in my senior year in college and was able to take a break. After that, I read part of my manuscript that I completed in front of a small audience and felt fine (with the support of my family). Made me too bland however to went with Geodon. F 22 2 months
30 mg? 1X day
3/11/2010
 3  bi-polar/schizophrenia i cant stop eating! and groggy morning my scary thoughts have not gone away i can tell they are calming down. F 26 2 weeks
10 mg 1X day
7/9/2010

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