ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Schizophrenia Tremendous weight gain, tiredness. Hope you have nothing better to do than sleep all the time, because zyprexa might make you feel pretty tired. I also gained 40 lbs in three months. F 29 1 years
8/13/2005
 3  depression weight gain, psoriasis, fatigue, trouble breathing This medicine works very well for acute or severe depression. Out of more than a dozen meds that I have tried it is the only med that signifigantly improved my debilitating depression. However the side effects are really terrible. Specifically the weight gain. If you have ever had a problem with psoriasis this is not the drug for you. F 34 4 months
7/24/2005
 1  mania 45 pound weight gain in 15 days, swelling and stiffness, induced asthma I put on 45 pounds in 15 days taking this drug. I was so swollen that I couldn't hold an ink pen to sign a check. Even worse than the weight gain (which was horrible) was the breathing difficulties that it caused. I had to focus completely on inhaling and exhaling. None of the asthma meds I took would work. As the med wore off my asthma would suddenly improve. I hated it and Lamictal works much better for me. I'm happy to hear that it has helped many people. F 34 15 days
7/22/2005
 5  bipolar II Some EPS the first 3 days but the worst side effect is clearly the food cravings. You just get the munchies hardcore! The bottomless pit. I use Zyprexa only as a temporary add on when I destabilize - its not in my regular med combo. Zyprexa killed my black thoughs and anxiety big time + restabilized my mood within 48 hours! Bravo. But still, you eat way too much on it, serious. M 27 21 days
7/15/2005
 2  acute psychotic episode weight gain (20 lbs) fatigue flattened emotions, slight depression and loss of wits severe withdrawal symptoms (including muscle twitches, nausea, vomiting, sensitivity to light and sound). Withdrawals lasted 2-3 months. Terrible physical withdrawal symptoms when you try to get off it (no craving though). Chemical description of zyprexa (olanzapine): 2-methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine. Benzodiazepine! In any case, withdrawals last for months. And no- vomiting 24/7 has nothing to do with the original illness coming back. Read up on supersensitivity psychosis on the internet. People who took zyprexa for other reasons than psychosis (i.e. depression), and never had a psychotic episode in their lives, reported that they got psychotic symptoms induced by this medication after withdrawing! Also, there are many cases of diabetes and tardive dyskenisia linked to this drug. If you're not on it, try a safer alternative. If you want to go off it, taper slow (cut pills into halves). F 31 8 months
7/13/2005
 3  bipolar I had a good result in stopping mania but now I am more depressed and having suicidal ideation. F 40
7/6/2005
 4  Bipolar 40 lb weight gain; cholesterol went up, so had to take a statin; blood sugars went up to the point I had to take pills for my diabetes, which had previously been diet-controlled. Off Zyprexa, weight decreased, cholesterol went back down, and I'm down 1/2 on the dosage of meds for diabetes. This was the best drug I'd used for a mood stabilizer since diagnoses 4 ys ago. Since I had to quit it, I've been trying nearly 2 yrs to find a substitute, to no avail. The P-doc had thought he could counter the weight loss by coupling it with an appetite-suppressing type of antidepressant. Wrong. Newest P-doc presently thought Geodon would be similar; but Geodon had other problems, just as limiting. Very frustrating. I'm still hoping to find something I like as well as Zyprexa. F 39 18 months
4/30/2005
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 5  bipolar 10 lb. weight gain, sleep good but tired upon waking for 30 min. or so I had been taking wellbutrin and depakote for the last several years and they had quit helping. The zyprexa has been excellant for bipolar. Has stopped most needless worrying. I am much calmer. Some might say it takes away personality but without it I tend to be manic. My employer seems to like the calmer me. So far its great. I needed the 10 lbs. as I lost 45 due to cancer treatment and I need another 10 and I will be happy with that. M 46 50 days
4/24/2005
 4  schizoaffective or bipolar disorder excessive sleeping; gained 30 pounds but then stabilized really does well at keeping unwanted and persistent thoughts out of my head; makes me more relaxed and content; moods/energy level are more stable now instead of always up and down M 29 5 years
4/18/2005
 1  anxiety akathesia--the feeling that you want to pace constantly. It is torture Zyprexa is an EVIL drug. Don't take it! You get withdrawal symptoms when you try to come off it. IT can also cause serious, permanent, deadly side effects. F 37 3 months
4/10/2005
 3  Sleelessness 35
3/31/2005
 3  depression sleepiness within 1/2 hour of taking it; weight gain of 10 lbs. despite no changes in eating habits and a new exercise program F 31 3 months
2/17/2005
 2  Bipolar II 10mg at bedtime made me feel numb and Kills your wit and personality too much. M 26 20 days
2/13/2005
 5  Depression increased appetite. I am really responding to this med! yeah. The increase in appetite is a good thing as I have always been skinny. I still plan to talk to my MD about a benzo suppliment for anxiety, but the zyprexa is really helping with the depression. F 41 5 days
2/12/2005
 4  ptsd, voices, poor concentration slept way too much, probably gained wt dont know didnt take it long enough...sleep was really deep tho and good... risperidal gave me nightmares! zy seriously clears my head up alot! its strong stuff but it works... i was so much more focused... ok i was heavily abused, so its hard to think sometimes, but this did help i was alot more focused...i might also have ADD tho, this might be a factor. yeah use this even if u think u dont need it... F 28 30 days
2/6/2005
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 2  Psychosis Rapid weight gain, constipation, odd sensations in arms and legs. Stopped psychotic thoughts and behaviour. Discontinued drug due to weight gain. M 45 1 months
1/31/2005
 1  Hallucinations Dizziness, almost blacking out, heart racing, weakness, tremors, coldsweat i had to stop after 2 or 3 days due to the fact that i couldnt think straight (like barely even remember my name) and worst of all, my heart raced so much i thought i was having a heart attack. F 17 3 days
1/20/2005
 4  Overwhelmed Its ok, for a sleep aid.. For the fist few days I was still sleepy for a few hours after, but after a short while, I was ok.. M 25
12/15/2004
 1  Bipolar Type 1 (suicide attempts) I always felt This is a very dangerous drug. Can cause diabetes, raise cholesterol levels, and cause other serious metabolic problems. Doctors who prescribed this for me in the hospital never warned me about any of the serious adverse reactions. There are many other meds that are safer to use. Fortunately my current psychiatrist realized that it was probably raising my cholesterol levels. M 40 8 months
11/25/2004
 1  Bipolar Type 1 - suicide attempts It completely messed up my cholesterol profile. Everything was dangerously out of normal ranges. Had 30lb weight gain. After stopping it for 4 months, values returned to normal. This drug is not safe. Can cause metabolic syndrome (diabetes, elevated cholesterol, etc.). There are many other safer alternatives. M 40 8 months
11/25/2004

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