ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Bipolar II I feel like a zombie, my personality is dampened. The zyprexa causes me to sleep 16 hours a day. I used the sleep-inducing quality to withdraw from Klonopin, so that was successful but I can't wake up clearly until the late evening. I also take 300 mg. wellbutrin XL and 150 mg. effexor daily. It's disrupted my reading ability. I haven't experienced weight gain but I do feel hungry all the time. I often feel numb, like I'm two steps behind everyone else. If anyone can relate to these symptoms, I'd appreciate a response. I'd like to know if the zyprexa is causing me to think I have brain damage, or if it's something else. F 49 4 weeks
9/16/2006
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 5   M 38 12 days
9/14/2006
 4  bipolar 1 Lots of weight gain! I ate a lot more, had a bigger appetite. Craved carbs and sugar.No other side effects. It works so well on my mania, anxiety, insomnia etc that I'm willing to deal with the weight gain. I try to resist carbs and sugar binges as much as I can. I'm afraid of the diabetes scare. F 46 1 years
9/11/2006
 4  bipolar 1 Weight gain like everybody does. I'm trying to FORCE myself away from the table since I've gained the weight because I EAT MORE. And I think it causes diabetes because I CRAVE sugar. Anyway, I love it and just wish it didn't cause weight gain and possibly diabetes. I'm staying with it for another year to see if I can drop some weight and level off. Seems that developing diabetes usually occurs within a year of starting, so I've passed that mark.It just works so well! F 46 1 years
9/11/2006
 5  depression and anxiety Serious weight gain, and not just because it made me hungrier, but because it messed with my metabolism (glucose levels). Most meds that make you gain weight do so because they just make you hungrier. Not so with Zyprexa, which can even cause Diabetes. Other side effects: sleepiness (but I wanted that), and anxiety when I missed a dose. I took 2.5 mg (5 when I was having situational problems). No sexual side effects. Oh, Zyprexa, How I love thee and also how I hate thee! I have treatment-resistent depression, with mild OCD and anxiety. I took Serzone 400mg and Wellbutrin XL 450 mg with no results, and my doctor decided to try Zyprexa to help "activate" the other drugs. It saved my life. I felt better within a week (after 6+ months of crippling depression), and it did not cause euphoria or significant cognitive changes. It just gave me a nice "buffer" between my anxiety/emotions and the outside world. This drug works for me. 2.5 was great, and I could take 5 when I had situational difficulties (short term) and I could tell the difference between the 2.5 and 5 in terms of my "overreaction" likeliness. I felt better than I have ever felt, it helped me sleep, and it did stabilize my mood. However, the weight gain was significant (20 pounds in a year or two), and the risk of Diabetes made me decide not to keep taking it as a long-term med. We will use it again s F 29 2.5 years
8/25/2006
 5  depression and anxiety same as below (I posted there, too, but it cut off my comments) We will use it again short-term if I ever have a major depressive episode again. It was a difficult decision to stop taking it, because it really did help me, but I am sticking to the atypical antidepressants, and Lamictal (to replce the Zyprexa) so long as I am doing okay...but I will not hesitate to go back to Zyprexa if I absolutely need to. I just wish the side effects weren't so awful. Weight gain is a big downer for me, because it makes me more depressed. F 29 2.5 years
8/25/2006
 5  Severe anxiety None noticable. I was having severe anxiety to the point that it caused me not to sleep for days. The doctor gave me Ambien which helped me sleep 4 to 5 1/2 hours of sleep a night but it was not restful. After going back to him he tried me on this saying it was very good at calming down people who can't calm down enough to rest. It worked very well for that. I've slept 9-10 hours every night since then. I'm only taking this for 2 weeks but I hope he gives me a prescription to use this as needed in the future because it helped me break the cycle on nearly the first dose. He prescribed me 5MG (I cut a 10MG tablet in two). M 28 10 days
8/20/2006
 1  Manic depression My son took it for two years (after having successfully taken lithium for years) then fell into a coma and died of profound hyperglycemia. He was 39 years old. I would not recommend this poison to anyone and think it should be taken off the market. Eli Lilly knew this drug was poison. Other countries had required them to put a warning on the label but not our country. They should go to jail in handcuffs. F 2 years
8/20/2006
 4  depression/bipolar ii Slurred speech and difficulty expressing thoughts. Sluggish thinking and fatigue. Feel stupid. But better. Better stupid than not better - right? Big Z seems to have broken this "spell" of recent depression. Have been on Welbutrin XL 300 mg and some supplemental Zoloft. But have felt very bad this past week, so I took a 5 mg left-over Zyprexa today and feel better already. My shrink had replaced the BigZ with Cymbalta, but that stuff is poison: detox is agony (2 mo. brain zaps). M 60 1 days
8/19/2006
 3  bipolar II I have been on zyprexa for a couple of years. I just got my bloodwork back and I have dangerously high cholesterol. We are going to have to try and find something else. The zyprexa did help me with suicidal thoughts F 45 2 years
8/3/2006
 3  Bipolar, Boderline Sleepyness and drowsiness, sleeping at work, acid reflux I am tired but my thougts are not running like crazy. Not enjoying the drowsiness. I am a front line worker and need to act fast. I am not able to think properly and am experiencing the world at about half the normal pace. People talk to me and I feel like I am under water. Can't keep my mind focused and my eyes are slow. F 33 2 days
8/3/2006
 3  Bipolar Disorder Weight gain and constant hunger. I gained about 40 pounds and just could not stop eating. Also felt very boring and flat...no personality at all. I just stopped a few days ago and already my appetite is back to its normal level and I feel better. The Zyprexa definitely helped with my racing thoughts but the side effects are just too awful. I have problems with depression and nothing depresses me more than being fat. F 58 365 days
8/1/2006
 1  PTSD WORTHLESS DANGEROUS DRUG THAT GAVE ME DIABETES Did you know that Lilly made nearly $3 billion last year on diabetic meds, Actos,Humulin and Byetta? Yes! They sell a drug that can cause diabetes and then turn a profit on the drugs that treat the condition that they may have caused in the first place! I was prescribed Zyprexa from 1996 until 2000. In early 2000 i was shocked to have an A1C test result of 13.9 (normal is 4-6) I have no history of diabetes in my family. All the psychiatrist I've interviewed and the information on line presents zyprexa as a worse offender than the other Atypicals such as seroquel.My doctor has stopped prescribing zyprexa altogether. The PDR classifies zyprexa as 'severe' for causing weight gain and diabetes and seroquel as 'moderate'. Of course the 50 year old Thorazine didn't cause diabetes and is many times cheaper but it could cause tardive dyskinesia. Where Eli Lilly's negligence comes in,is their KNOWING and not informing consumers (black box warning) until the FDA demanded i M 49 60 months
8/1/2006
 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 3  fibromyalgia Weight gain! Acne, loss of libido, hormone inbalances, sleepiness, decreased IQ and emotional numbness. Although the zyprexa really helped with pain it has caused some nasty side effects. The sugar cravings are torture I feel like an addict. I have gained 50ib and think about carbohydrates and surgary foods constantly. I had to drop out of college because I was not as mentally alert and find it difficult to do anything but sit in a chair and watch T.V. Doctor has refused to change my medication and if I stop taking it the pain gets really bad. I feel miserable just hoping guaifenesin will work, have heard great things. F 32 3 years
7/1/2006
 1  Schizophrenia Zyprexa (Generic: olanzapine) used by millions of Americans to Schizophrenia and bipolar disorder has been linked to linked to, high blood sugar and Diabetes, Hyperglycemia, Ketoacidosis, Pancreatitis, Neuroleptic Malignant Syndrome (NMS), Tardive Dyskinesia (TD), Diabetic Comas and death. M 29
6/30/2006
 5  Mixed states re Bipolar Disorder some constipation, some bloating. Works wonders. The best of all the atypicals. I highly recommend it. Also great for sleep. F 49 2 months
6/29/2006
 1  Psychotic dysorder Weight gain, Being tired most of the day, Uncontrolled eye movement, Hallucinations/nightmares including awakening without being able to move - lasting several minutes during that time bouncing into hallucinations and hearing voices, Being Numb , depression. I would recommend this medication only for acute symptoms, when there are no alternative, if you don't experience side effects. i would like to point out - beware of psychiatrists they subscribe medications much to easily, dont become a lab testing mouse for them. M 28 2 years
6/18/2006
 2  bipolar Sleepy, great to get a good nights sleep. Morning/day/evening Restlessness, the kind where you wanna kill yourself. Pacing around like a mad fool thinking of slitting my wrists.pop one then your so chill an hour later wake up, repeate the restlessness - Odd space outs, but could still focus for the most part. I fainted once, dunno if it was the med or not. It is too bad made me wanna kill myself with restlessness otherwise id take the stuff You may wanna try this if your crazy, but beware it might make ya more crazy ! like any med, everyone is different, one person will curse a med while someone else will praise it. I took it on and off but when I took it steady for a month I was looped with restlessness like you cant imagine. It is too bad about that cause other than that I didnt mind it is the key word. restless. M 25 4 weeks
6/17/2006
 2  anxiety, paranoya took 15 pounds in a month, felt like a zombie: lost of emotions and general feeling that everything doesnt matter at all. had to stop the medication because of uncontroled mouth movements. do not take zyprexa unless you realy cant function in everyday life. try to avoid that medication if you can. Im sure it is good for people who have realy big problems that but think about it before taking it, you wont have any feelings like passion or love. This medication could be good for treating anorexia since you get realy hungry all the time and you dont seem to care about getting weight while under zyprexa.... if fact, you dont seem to care about anything at all in life, the good and the bad. M 24 1 months
5/22/2006

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