ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  bipolar II extreme drowsiness, feeling like a zombie This drug was by far the worst out of all the meds I have tried!!! I was on only 2.5 mg (in addition to 100 mg Topamax and 75 mg Effexor XR). My doctor told me that it would help augment the Effexor XR and in turn help with my anxiety. I was reluctant to take it because I read all over the place that it caused major, major weight gain but then I figured since I was on the other two meds (which suppress appetite) that I should be okay. Well, it didn't make me gain weight! Thank goodness! My intuition was right about that! Anywho, moving on....I had to sleep 10-12 hours each night and [if time allowed] take a two hour nap in the afternoon. That would be fine every now and then, but NOT on a DAILY basis! The zombie-effect was totally horrid! I was indifferent towards nearly everything! My creativity and intellect was dulled; it was extremely difficult to think =( I had almost no personality. This boomeranged of course. When I thought about what I was turning into, I became frighten F 3 months
12/29/2007
 5  postpartum ocd very minimal weight gain 5-6 lbs while on 2.5 dose. 5.0 made me drowsy during the day so had to cut it down to half. I took 2.5 zyprexa along with 20 mg celexa. I slept better at night. Intrusive thoughts backed off the next day! Anxiety was less because of this. My thinking was more clear during the day. F 37 5 months
12/27/2007
 4  Treatment Resistant Depression Mild muscle stiffness, sensation of bodily heaviness sometimes, dry mouth sometimes, feeling the need for 8+ hours sleep. Side efects all mild and easy to cope with. First or second day this kicked in and I felt the depression lift. To be more specific, it quietened my mind, turned the volume down on my endless negative ruminations. Allowed me to feel more in the present moment without it being seen through a completely negative filter. More sociable. More balanced. Less tearful. More able to handle upsetting things in my life. Now i'm into my third week these benefits have been maintained but I still feel mildly depressed, I think the effectiveness may have decreased a little bit. I take 5mg and i'm contemplating trying 10mg (opinions very welcome, please email me) to see if I can get back to being euthymic as I was initially. Overall a good drug fo r me. F 30 21 days
12/26/2007
 1  anxiety and POSSIBLE bi-polar ABSOLUTE ADVERSE EFFECTS! Took medication as directed by family doctor before going to sleep, and woke up with facial paralysis, leg muscle rigidity, maybe even partial paralysis, multiple voices, an overall Freak show of a psychotic episode. I could not control muscle tremors or twitching, dry eyes, eye pain- EXTREME short term memory loss (amnesia) - broke out in violence towards family, destroyed furniture and dishware while experiencing the memory loss and psychosis and had no idea.......lost logic and tried driving to work- nearly totalled vehicle twice in 30 mins. Upon leaving work....Slept for 16 hours. THIS DRUG IS FOR SERIOUS CASES ONLY! I wouldn't recommend anyone taking this medication even if the doctor thinks it will help even out moods and help sleep. Unless you have major psychosis, DO NOT TAKE THIS DRUG. M 24 1 days
12/22/2007
 5  bipolar weight gain ... other than weight gain zyprexa (10mg) has worked a treat for me. When I first took it it took only 1-2 weeks to take me out of a very anxious state that anti-depressants did not touch. F 50 4 years
12/20/2007
 4  bi-polar 25+lb. weight gain in less than 8 weeks,off & on flat affect, diabetes, the need for 10 hrs. sleep & difficult waking up It took 5 years to find a med. that worked. Within a week my mood swings lessened and I felt human again. Zyprexa saved my life. At times I'd feel real flat & my vivacious personality had lessend considerably. My psychiatrist added Wellbutrin to Zyprexa and Lithium. After 9 years, I'm now off of the Zyprexa because my glucose nos. went into diabetes mode. I had no idea that was a side effect. I'm back to feeling like me again (w/out the extreme swings). I do miss the ability to sleep late on the weekends! F 59 9 years
12/20/2007
 4  Treatment Resistant Depression dry mouth, stiff muscles. I take 5mg with moclobemide (RMAOI) at night. I feel much less depressed, to be more specific - I'm no longer constantly ruminating over everything negative, my mind is lighter. I feel more assertive and have more 'oomph'. I generally feel better, I just hope it lasts as its very early days, and most things tend to poop out on me (and thats not depressive thinking, its based on experience!). I felt it working within the first few days. Also my voice is sounding stronger, strange thing but depression/anxiety makes my voice sound a bit strangled. F 31 11 days
12/17/2007
 4  anxiety with PDD-NOS lethargy, weight gain, constant hunger. This is for my 11 yr old son who is diagnosed with PDD-NOS. He was diagnosed with it before he began the zyprexa. After a week of taking zyprexa, he was able to leave the house and not have a meltdown! Now he is able to be in a noisy room, around bright lights, and close to other kids. He eats almost anything now and before he ever started any meds, he was severely underweight. His anxiety is so much better. He sleeps about 10 hours but wakes up slowly! I am concerned about the weight gain though. He is 11 and weighs 94 lbs! M 11 3 days
12/16/2007
 3  Bipolar The only side effect I've noticed is a constant hunger and gas F 34 12 days
12/13/2007
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 1  bipolor disorder weight 165 before zyprexa. While taking 7.5 mg at bed-time, gained 70 pounds within a year(235 pounds). I also experience panic attacks which I never had before taking medication. Had muscle spasms in legs. Always eating!!!!!!!! Tired all the time. Had to stop taking it also increased blood pressure and cholestrol. Trouble buying Clothes that fit. Self-image low so was self-esteem. I feel this medication is dangerous to your health, even if it works to control your illnees. The reason being is that you can end up with diabetes, high blood pressure, etc. DON'T LET THE MEDICATION OR DOCTOR CONTROL YOUR LIFE OR HEALTH, IF YOU DO YOU WILL BE TAKING EVEN MORE MEDICATION. I Seen a second doctor, besides my regular doctor, she prescribed rispardol 37.5 mg consta every two weeks. Been on it for almost 2 years and it is working wonders. My blood pressure is 134/64, my weight 175 pounds, and choletrol is low. THis drug feels safer and heathier and less dangerous, the zyprexa. M 37 4.5 days
12/9/2007
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 5  bipolar sleepy kills mania like flys on a lightbulb M 20 1 months
11/27/2007
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 1  Schizoaffective Bipolar Type It made me more psychotic. I felt like I could feel the particles in my food and the molecules in water. I was delusional on this drug when I had not been before. I could not sleep. I could not eat. I ended up in psych emergency in the middle of the night. F 22 5 days
11/27/2007
 3  Schizoaffective disorder EXTREME weight gain - 85 lbs in three months without any success in shedding the weight. Sexual dysfunction. Dry mouth. I would not wish this drug on my worst enemy. Sure, it does a really good job of controlling psychotic symptoms, but there's better ways than this, ways without these extremes in side effects. M 30 2 years
11/24/2007
 5  Bi-polar NONE It has worked great with my Bi-polar, enabling me to sleep and decreasing my paranoid thinking. It also keeps my manias from being as severe and pronounced. M 41 9 years
11/17/2007
 5  Bipolar II, Panic Disorder Weight Gain. 20 lbs in 8 weeks -- no doubt it would have reached 100+++ lbs if had continued. You eat because you have to eat (will power has nothing to do with it) plus your metabolism changes radically. This drug causes blind, crazy hunger -- mostly for sweets. As a result developed Metabolic Syndrome (Sugar levels increased and needed to take Metformin to control, which it didn't. The minor side effects: tired in am, constipation, RLS and a tad spacey/loopy when ever I got tired. The best drug (combined with Zoloft) for mood swings, stability, anxiety, depression, mania and general happiness that I've ever taken. I felt great on this drug, 100% normal. Unfortunately the side effects of weight gain and metabolic syndrome got out of hand and I had to stop. I feel like Algernon -- I've had a taste of what normal people feel like and now I have to go back into my illness. If you can take this drug without weight gain and metabolism issues you may have hit the jack pot. F 50 8 weeks
11/15/2007
 1  Bipolar 30 pound weight gain and it turned me into a "zombie" This was the first medication I was put on after being diagnoised with being bipolar. I instantly blew up weight wise... who does that to a woman? To make matters worse, the medicine wasn't helping and my doctor just kept uping the dose which changed my whole personality. I am a very outgoing, people person. I turned into someone who it took extra effort just to leave the house just to run to the store. I wouldn't recommend this to anyone. F 25 1 years
11/13/2007
 2  brief psychotic episodes weight gain 40 lbs in a year, adversely affected my lipid count/triglycerides, zombie effect some days, sometimes confusion & lethargy and feelings of depression It did make my psychotic symptoms go away while in hospital, but I don't like taking it. Concerned about the possibility of diabetes linked with Zyprexa. I've read the anti-psychotic is only meant for short term use with my diagnosis, yet my pyschitrist insists I should be on it at least two years for fears of relapse. I did have two relapses in the past year but I think it was due to stressors, not withdrawal of Zyprexa. I went off it on my own twice and feel like getting off it again. The weight gain is crazy and to lessen the side effects I have halved the prescribed dose of 10mg - I am being tapered off slowly (too slowly in my opinion) to 7.5mg and then 5 mg over the course of treatment. I will see if I stay on it or not. I am concerned about relapses but also concerned what continued use of the drug may do too. F 37 65 days
11/8/2007
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 2  Anxiety Tremendous weight gain (70 pounds +)in weeks, being fat now totally depressing me.Stupendous hunger-always an empty tank.Stroke like symptoms,excessive thirst during night, emotional & sexual detachment. Perhaps Zyprexa is for the short haul/emergency presciption.It has no place as a long term treatment as the horrendous side effects manifest themselves as other major health concerns. F 43 9 days
11/6/2007
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 2  Psychosis Sedation, and need for excessive sleep I almost overdosed on this because i would take a 15mg tablet and it would kick in and i would slow down but it wouldn't rid me of my volatile urges and my hallucinations so therefor i took more... its all i had and i couldn't afford a trip to the ER M 3 months
11/4/2007
 2  schizoaffective Raised PROLACTIN levels, weight gain, oversleeping. Have stopped taking 2.5mg Zyprexa since 6 weeks. Have struggled with short amounts of sleep and a cloudy head.The weight loss is so far 4 kilos. Hope I have the strength to keep going without it. Girls- beware of the raised Prolactin levels- this is a common side effect. Check with your Dr what this means. F 39 5 years
10/30/2007

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