AYGESTIN Reviews (NORETHINDRONE ACETATE)

Average Rating: 2.9 (163 Ratings)

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 ESTROGENS PROGESTINS

 Type: Rx Drug

  

AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AYGESTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AYGESTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Menorrhagia HOrrible mood swings, depression, swelling of feet and hands, drop in blood sugars. Irritable, very sad. I like the fact that I have some relief from teh bleeding it does help, but the sadness that I have experience is overwhelming. I have been very depressed and iritable. I can hardly bend my hands and toes. The swelling is painfull and isn't going away even though I quit med 2 days ago. I will not ever take this med again. F 27 5 weeks
5mg 1X day
6/7/2010
 3  Endometriosis My pain during my cycle were like "birth pains". I bleed for 7 days HEAVY. I have been on this pill now for 3 weeks. The pain is gone. The HEAVY cycle is gone. Yet I have been bleeding for two weeks, I am always crying, I have acne now, and I do not know when I will stop bleeding. I have a husband and two children. I try not to show them I worry but I am scared! F 36 3 weeks
5 1X day
5/31/2010
 3  Prolonged and heavy bleeding It helped to stopped the bleeding. Although, by simply taking 3 Advils in the morning and 3 Advils at night (I didn't know tha Advil helped a lot with bleeding from the uterus) would have helped, before taking Aygesting. Again, it did help the bleeding, but I will probably stop today or tomorrow after 6 days of taking this horrible drug. My doctor prescribed for 12 days, but I cannot do this to myself. It is toxic to me. This is NOT a natural hormone is synthetic and has many side effects. For me, it has given me insomnia, hart palpitations, shortness of breath, tingling in the face as if I had touched something caustic + bad dreams, mood swings, especially irritability! This is must not be good for my health. I cannot take 12 days of this! Better try a higher dosis of natural progesterone. F 54 6 days
5 mg 1X day
5/21/2010
 3  Endo I had weight gain, serious increase in appitite, terrible mood swings and irritibility, insomnia,headaches, and acne. It worked well for my pain but I began bleeding yesterday and have decided that the bad more then out weighs the good for me. I will be stopping medication as of today. Good Luck! F 26 3 months
5mg 1X day
5/5/2010
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 5  heavy bleeding for prolonged time swelling of legs and feet which was taken care of by a simple water pill. it stopped the bleeding within a few hours the day i started taking it and have been on it for almost a year and a half, but am afraid when stopping, the bleeding will start up again and we are ready for kids now... F 29 16 months
5 mg 1X day
2/18/2010
 2  endo second attempt at trying this med last time i stopped because i thougt it made me crazy sad, moody no change in pain . have had 4 laps with no luck pain in left leg, knee, foot, back unbearable at times, taking again now for about a week or so feelings of sadness returning, pain still there, tryingot stick with it, have follow up next week and hopefully i will be taken off this med. do not like feeling this way. F 38 14 days
12/7/2009
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 5  endo i have had no bad side effects. actually, my breast size increased. Has helped me a great deal. I don't have a period or it is very very light. Has helped with the cramps. F 31 6 months
11/30/2009
 2  ENDO lower abdomonial pain I was put on this med to reduce the pain and stopped the heavy/frequent periods. Since being on the med it seems that the pain is worst and i have become meaner than normal. Have stopped talking to a v ery close friend bc of this med. F 33 12 days
11/15/2009
 1  endometriosis, bad cramps during cy I cont. to have bad cramps so I stopped using Aygestin, upon stopping I bled heavily. I soaked thru 2-3 pads and hour and had to sleep in Depends. This happened for 2 days ( 2weeks after my first post Aygestin cycle), then stopped abruptly. While I bled I passed clots so large I thought I was having a miscarriage!!! Then bleeding returned 2wks later....while lovemaking. Heavy Heavy bleeding. my gyn advised me to start taking the Aygestin again to control the bleeding until I had an ultrasound to rule out fibroids. They were ruled out and I promptly stopped the Aygestin which was originally prescribed for endo pain NOT heavy periods. I have been off Aygestion for 3 days and have started a cycle. I am very scared. I don't know what this drug has done to my body and how long it takes to leave my system. I used to have very regular periods and now I just don't know when I'll bleed. I am scared, sad, angry, and dissatisfied. Has this happened to anyone else?? F 40 120 days
11/10/2009
 5  endometriosis/heavy bleeding None...except when taking the meds at night I had alot of energy (2 hours worth)-so I cleaned. I slept well. and the key is to DRINK ALOT OF WATER ALL DAY and eat right. When I took the meds I drank alot of water with them and was advised to take the meds 12 hours apart..My dosage was strong. Plus I became anemic from the bleeding prior so I have been taking slow fe twice a day with no side effects. This drug has stopped my vaginal bleeding instantly,(day 2 of meds). I was on provera prior and it didn't do the trick. I am currently on day 6 with no bleeding and my life is getting back to normal. yeah! F 43 7 days
11/4/2009
 4  endometriosis none I felt so much better the 2nd day I took aygestin. I was in so much pain, so tired and was becoming more and more depressed each day that my symptoms persisted. I'm 28, a hysterectomy was not an option - this is working! F 28 7 days
11/3/2009
 3  Endometriosis Extreme anxiety and restlessness when I laid down to sleep. Kept getting the urge to want to tense and stretch all my muscles. Very strange, have never experienced that feeling before. Starting to drive me crazy. Got put on Aygestin after my 3rd endo laparoscopy hopefully trying to prolong the next surgery & pain. F 20 3 weeks
9/7/2009
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 1  endometrial hyperplasia acne, nausea, horrible headaches, asthma attacks, dizziness, irritability, blurry vision, numbness and tingling, swollen hands and feet, shortness of breath, pain in calves, period so bad I needed LOTS of vicodin I never should have been prescribed this!!!!! History of blood clots, phlebitis, CHF, strokes, asthma.... My life has become a living hell. I am very disabled from taking this med. I'm quitting today! F 53 2 months
8/30/2009
 2  Endometriosis weight gain 8 lbs, bloating, insomnia, bad dreams ,cholesterol increased 40 pts, high blood pressure, costochondritis (rib/breastbone pain), Have been able to take a birth control pill for a few years to control endo. Started Aygestin when the symptoms got out of control again. But this med is now not able to hold back the pain either. It's like toothpicks holding back the Atlantic ocean. Not happy with side effects - especially wt gain and cholesterol increase! I am at the gym 3-5 days with no effect. Having a scope in two days and want a hysterectomy soon!! Can't wait to get off this med! Can't stop now b/c the endo pain would be too bad. F 41 9 months
7/26/2009
 4  no period/ no ovulation EXTREME mood swings!!!! VERY irritable! EXTREME bloating! it looked like i was 5 months pregnant! i have been trying to get pregnant for over 10 months now. all of a sudden i stopped having my period. so my doctor said to take the aygestin to make me have a period, then followed by fertility drugs. i have never been more miserable, bloated, irritable, and sensitive in my life. i actually used very fowl language to my coworkers and boss while on this medicine. i'm lucky i wasn't fired. the swelling and bloating is to the extreme. i don't fit into my clothes anymore because of my extended stomach. on the plus side.... i did finally start my period today... yay!! so that's in the right step to having a baby. i am very excited that by the doctor's instructions, i should be pregnant by this time next month! F 23 10 days
6/25/2009
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 5  adenomyosis; breakthrough bleeding small cramps every now and then, nothing like what I experienced before. some trembling of my hands at the beginning but now that has subsided. I started taking Aygestin 5mg bid March 2, 2009 and have been very pleased with the results. I have completely stopped bleeding and my severe, painful cramps have stopped. I am nearing the 6-month mark and my doc recommended titrating to 15mg/day to see if that stops the small cramping. I am just concerned about the long-term effects of this drug, especially anxious about the risk of blood clots. And, I am especially interested in knowing more about the "intolerable breakthrough bleeding" that is presumed to begin at some point after taking this drug for a while. Why does this happen and what do you do then?! Does it happen to everyone that takes this medicine? F 28 3 months
5/28/2009
 2  uterine fibroids weight gain, moodiness, bleeding for close to a month and counting, fatigue, palpitations. I will ask my doctor for an alternative solution to my medical problem, or change doctors. Before taking this medication, I experienced severe cramping, heavy bleeding, and blood clots for the first day of my cycle. Now, the only difference is, I have no pain with my cycle, but my cycle doesn't seem to want to end! F 51 1 months
5/6/2009
 3  PROLONGER PERIODS Bloating, weight gain, calf cramping, menstral cramping, increased blood pressure, palpitations, acne, headache, muscle pain It stopped the bleeding with some break through, but I just do not feel well taking it. I want to stop it. Any side effects I told my gyn (nurse practioner) she ignored them and said that they were not side effects. I have since changed gyn's. F 50 90 days
4/21/2009
 5  Endometriosis & adhesions None thus far... I feel alot more mellow and laid back, but this is only the 2nd day of taking the medication. So far,within the first day of dosing, my heavy excrutiating period went away!! I'm very greatful for the medication as I'm not ready for a hysterectomy, time will tell, and the comments scare me to death, but I know that people are more likely to post the bad experiences than the good, I just pray it works as it's supposed to without all the awful side affects that some of you have experienced on this board. I pray that your pain and side affects subside, and you are granted peace & comfort! F 39 2 days
3/19/2009
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 2  Heavy period and bad cramps none. I have been on this for 2 months now. The frist month was great. I spotted a few days for my period in Jan. and now in Feb. I have been on my period for 11 days. Cramping like I use to and blood clots like before. I was given this after a DNC and Hysterscopy. I go back to the Dr. in April. Probably will be going before then if I dont stop my period. F 36 2 months
2/22/2009
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