AYGESTIN Reviews (NORETHINDRONE ACETATE)

Average Rating: 2.9 (163 Ratings)

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 Type: Rx Drug

  

AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AYGESTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AYGESTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  2 months missed period Abdominal pain that comes and goes, hard nipples non stop, irritability, PMS I didn't experience this the first time I took this the only thing that happened the first time was a sever case of PMS for about 3 periods after taking this, but then it subsided eventually. F 22 5 days
5 MG 2X day
4/30/2012
 1  Endometriosis Irritability, leg pains, anxiety, nausea, headache I expressed significant concerns about aygestin affecting my mood to my doctor who assured me that it would not be an issue. I took it for approx 2 weeks, 5mg a day. I experienced noticeable irritability. I had leg pains (sort of like growing pains) and didnt realize why til after reading some of the other reviews. I also had anxiety. I stopped taking it two days ago...started my period today (even though I just had a period 2 weeks ago) and I have had EXCRUTIATING headaches both days. I am also experiencing nausea and still having anxiety. I hated this medicine...now my body is all out of whack. F 24 14 days
5MG 1X day
4/26/2012
 1  No period Terrible insomnia, it is 3 a.m. Right now. Exhausted during the day, zero sex drive, irritability out of control. Weight gain and ravenous appetite. Bloating and constipation. Stopping this medication today. F 28 6 days
5 mg
2/21/2012
 5  Heavy Uncontrollable Bleeding Highly satisfied. No weight gain. A little acne but controllable. Stopped my bleeding! Diagnosed with Von Willibrands Disease and had an IUD placed and was put on a taper of this medicine. I am down to 5 mgs this week and started bleeding. Rather stay on the higher dose!! I would recommend this medicine in luie of a hystorectomy any day. F 33 3 weeks
10mg Day
2/10/2012
Email
 1  Endometriosis/bleeding and pain Bleeding, weight gain of 10 lbs, irritablity, migraines, swelling of extremities from fluid, bloating, increase in appetite, always tired, and abdominal pain. I also get tingling in my one foot, and easy bruising. I CAN'T WAIT TO GET OFF THIS MEDICATION!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!! F 38 14 days
2X O
1/25/2012
 1  Heavy menstrual bleeding I find that I am extremely depressed and very irritable. Weight gain. I cannot wait untill I am done with this medication. F 40 15 days
5MG 3X day
10/31/2011
 3  Prolonged period (over 1 month) constant state of PMS: light cramping, decreased libido, lower energy, cravings, irritation, light acne, etc. I only have to take it for 3 weeks to kick my cycle back into gear. It has stopped the bleeding but added on these other side effects. Can't wait until I'm done with it. F 35 3 weeks
5 mg 1X day
6/13/2011
 4  Heavy prolonged bleeding from fibro It has controlled the bleeding very well. Also the pain is almost completely gone. I have noticed small dark spots on skin. Recently diagonosed with high blood pressure but that was after taking for 6 years. Weight gain of about 20 lbs. Hoping to soon go off aygestin because I am going thru menopause and should be able to quit taking this medicine soon. It has saved me from a hysterectomy. F 48 6 years
2.5 mg 1X day
5/31/2011
 5   extreme weight gain, super tired at random times, brain farts, hot flashes, mood swings in the beginning, leg cramps at times i had uncontrolled bleeding to the point of needing a blood transfusion (a new Dr,) and a D&C, Two weeks later it started up all over again, Fourth trip to the ER later, I was finally given this and was told to take 4 the first day, until the bleeding subsided and stopped. It took a few days but it finally stopped and was an answer to my prayers. I went from "bleeding a river" (said by an ER Dr.) to not having to stress over it anymore. I wish there weren't side effects, but I certainly would take them over the alternative ANY day, F 48 2 years
5MG 2X day
5/18/2011
 5  adenomyosis After 4 months my blood pressure went from 100/70 to 180/110 with severe tachycardia when combining this with Advil. This med spared me from bleeding to death. I posted here to warn other users about the hypertension risk when using this at high doses, especially when combining it with Advil, Tylenol or other NSAIDs. The side effects went away a few months after discontinuing both aygestin and advil. F 53 5 months
5 mg 3X day
12/4/2010
Email
 3  longterm bleeding Nausea, loss of appetite, weight gain, mood swings, depression, anxiety, leg pain, back pain, cramping, headache, weakness, and shakes. I started taking Aygestin after having my second child and after two months I was still bleeding. Soaking up to a pad a hour. My Ob wrote a Rx for this medication. Instructed to take it every six hours til bleeding stopped, than twice a day. I stopped bleeding after a day. Almost a week later I started bleeding again very heavily. At first it was like a miracle drug, than the headaches, dizziness, nausea, vomiting, and tiredness. The shakes hit almost instantly. Now with a three year old and a two month old I could not function like this. However with also going too school I can not keep getting up every half hour to forty five mins to check my tampon. F 24 1 weeks
5 MG 1X H
11/26/2010
Email
 3  fibroid/heavy period at first it seemed a miracle, within 5hrs of starting pills, the bleeding stopped after 5 unbearable days! I seemed to have no real side effects besides some weight gain but then the leg pain started in the left leg and it was constant and at times increased so bad I cried. After 1 week of this my doctor told me to stop the med as it seems that it was causing damage to my common peroneal nerve. The next day the leg pain was gone but unfortunately the bleeding started again. cannot wait until surgery! F 40 3 weeks
5mg 2X day
11/8/2010
 5  uterius ceis I was so very nervous about taking this medication but, it have work great for me. I think you got to workout at the gym or do some type of walking etc. I notice the water wght gain, but, other than that it has work wonderful for me. The key is working out with this medicine will help. Drink alot of water and workout is the key. I did notice a weight gain but, thats it and it was only 5lbs no more. F 40 9 days
5mg 1X day
11/1/2010
Email
 4  Endometriosis,Adenomyosis, Fibroids weight gain, irritability, depression, insomnia I have been on Aygestin for 3 months now. The first month I was very pleased with it, as it took away a lot of my pain. The next period I got lasted for 2 weeks and was very painful. I almost stopped taking the medication, but decided to go for 1 more month. I haven't had a period now for 2 months, and am pain-free. My biggest complaint is the weight gain. I am very pleased with the medication now F 44 4 months
5 mg 1X day
10/6/2010
 4  Uterine septum resection (pre-op) fluid retention, depression, suppressed appetite F 29 19 days
5mg 1X day
8/8/2010
Email

Patient History
 2  Hyperplasia Shortness of breath, depression, fatigue, blurry vision I was was told to take this drug 3x per day for 7 days, then 2x per day for 7 days, then 1x per day for 7 days. I'm now on my 14th day. The bleeding has stopped but I'm experiencing depression and fatigue to the point that I can't really handle my daily activities. I don't feel like myself and can't see staying on this drug, I need an alternative. Have been told an IUD may be a possibility to help with the hyperplasia. F 49 28 days
5 MG 3X day
7/26/2010
 5  HEAVY CYCLES BLOTING,INSOMINA AT TIMES,NIGHT SWEATS,HOT FLASHES,COLD INTOLERANCE AT TIMES,NAUSEA(MILD)WEIGHT GAIN(MILD) HEADACES AT TIMES! AYGESTIN HAS BEEN A LIFE SAVER FOR ME, NO MORE HEAVY CYCLES,NO MORE ANEMIC,I FEEL GREAT!NO HYSTERECTOMY AT THIS TIME!! I THINK THIS MEDICATION IS WONDERFUL! ITS BEEN SIX MONTHS NO SPOTTING OR CYCLES, SEX DRIVE INCREASE!! AGE 39! F 39 6 months
5MG 1X day
7/22/2010
Email
 1  PMDD & Nausea, Depression, Terrible Cramping on one side, loss of appetite I was prescribed Aygestin to help with mood swings associated w/PMDD and with irregular periods and directed to take it beginning mid-cycle. Since I'm so sensitive to medications, I was also instructed to only take a 1/2 of a pill. Each day I'd wake up with nausea & by the 4th day depression kicked into high gear. I found it difficult to even get out of bed. Last night I didn't take it at all and today I feel a lot better though not 100% yet. F 34 7 days
half of 5m 1X O
7/15/2010
 5  heavy bleeding, horendous cramping No side effects! This was a miracle and I avoided having a hysterectomy. Periods stopped completely - no side effects at all and only had to take 5 mg. per day. I went from periods so bad I could not function to feeling great and no periods at all. I have just stopped taking this a few days ago as I am now 55 and hoping all this is fially over - but it really made my life so much better! F 55 5 years
5 mg 1X day
6/16/2010
Email
 4  Endometriosis/Heavy bleeding/cramps Acne, spotting, moody, weight gain, dark spots on face, extra facial hair I have been on this drug for a very long time. I had 6 endo surgery's a D&C and had horrible periods for years. This has cured all of that but I am a smoker and I read that I should NEVER be taking this while I smoke and am over 35years old (because of blood clots and stroke). I will be going to my Dr next week and will go over this fact with him. It has never been mentioned to me that this was such a risk. I want to come off this medication but my only hope is a hysterectomy and then I will just be on another artifical hormone anyway. F 43 7 years
15 1X day
6/15/2010

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