AYGESTIN Reviews (NORETHINDRONE ACETATE)

Average Rating: 2.9 (163 Ratings)

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 Type: Rx Drug

  

AYGESTIN  (NORETHINDRONE ACETATE):  This medication is used to treat women with abnormal bleeding from the uterus. It is also used to treat women who have stopped having menstrual periods for several months (amenorrhea) but who are not pregnant or going through menopause. In addition, this medication is used to treat a condition (endometriosis) in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods. Norethindrone is a type of female hormone (progestin). It is like the hormone progesterone that your body makes naturally. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods. This medication must not be used to test for pregnancy. Progestins are not effective in preventing miscarriages.   FDA Approval Date: 1982-04-21 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on AYGESTIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR AYGESTINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  endo and ovarian cysts I had severe bleeding for years and multiple "soccer ball size" ovarian cysts, one ovary removed. i was anemic at one point. Cramps so bad i would vomit and be stuck in bed for 2 days each month. I went thru hell. This med had stopped my cycle so i am pain free. But now i have the weight gain, hot flashes while sleeping, dark patches on nose and around mouth after a day in the sun (it fades). It took a while to get my body ajusted but most have eased up. I would choose those side affects over the MISERY i was living for years. I was always in some sort of pain. Always. I do feel like its time to up the dosage tho so i will discuss at next doc appt. I was too scared to try lupron so im glad i did this. F 29 9 months
10mg/day
9/17/2013
 5  Heavy Bleeding This medication has been very helpful to me. Basically holding back my periods and preventing me from having a hysterectomy at this time. I just hope to use these to get myself into menopause which I don't think is very far off. I have had the worst heavy periods in the past few years and this stuff just stopped them in their tracks. Although, I did have one 2 day breakthough very heavy, but It stopped. I have had noticed my skin is more acne prone, so I have switched to acne products and for the most part it is under control. I seem to have a little joint pain, but I am not sure this is the med doing it. I have to say I am more depressed than usual. I cannot comment on weight since I have been eating out a lot the past few months, so I don't think the few extra pounds are from the aygestin. Overall it has made a huge difference for me. F 48 9 months
10 1X day
9/3/2013
 4  Prolonged Bleeding and Polyps Mood Swings, Sweating, Mild Headaches, Sleep Problems Started taking 5 mg of Aygestin to stop prolonged bleeding, after two weeks the bleeding had not stopped so my doctor increased my dosage to 10 mg. Bleeding stopped about 30 days after starting the medication. The worst thing about the medication for me has been the mood swings and waking up in the night wide awake which I have never done before. F 53 45 days
10 mg 1X day
8/30/2013
 4  Heavy, prolonged bleeding Bloating, blurred vision, headaches, cramping throughout month, fatigue, dry mouth, irritability, crying, depression. I was prescribed this medication due to prolonged menstrual bleeding for over a month due to fibroids. Which caused me to become anemic. This medicine is wonderful as far as controlling excessive bleeding and managing cycles. The downside is the mood changes: Irritability, crying spells , memory loss, and slight depression. I hate the negative side of this med because the benefits help save me. F 33 4 months
10mg/day
8/27/2013
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 3  Extremely heavy bleeding Unbelievable headaches every day not cured by motrin or caffeine. Weird calf and knee pain. Uncontrollable appetite. Acne and some weight gain. Slight moodiness. I smoke so I thought the calf and knee pain was from a clot starting. It stopped the bleeding slowly though. F 32 2 weeks
20 Mg
7/23/2013
 2  Endometriosis Weight gain, acne, mood swings. F 21 3 months
5 mg
6/24/2013
 5  pcos & irregular & heavy periods No major side effects. It actually helped me keep my weight down... Decreased appetite. Stopped pain from cysts. Shut period off completely. No spotting. Wonderful drug. F 27 4 years
10mg
6/13/2013
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 1  PCOS, endometriosis, heavy bleeding Breast milk, Extreme moodiness, crying, depression, leg pain (like growing pains), insomnia, weird dreams, NO interest in sex, abdominal pain, cramps, bloating, constipation, shakiness, anxiety, weight gain, increased appetite, lower back pain. My ovaries hurt even worse. This has been Horrible! F 42 7 days
5 mg
5/22/2013
 2  Dysfunctional Uterine Bleeding Severe bloating, leg pain, cardiac discomfort when trying to lay flat, extremely agitated. Although it has stopped the bleeding, it is wreaking havoc on my body and mood. I feel absolutely miserable and want to crawl out of my skin. F 40 5 days
5mgx2/day
3/24/2013
 5  endo Swelling of d legs. I liked this side effect because I have chicken legs =D...after my histeroscopy surgery d swelling went away.I wwonder if I could continue taking it 4 that purposes only? To have my legs thicker? =) F 46 1 months
3M
3/23/2013
Email
 2  Endometriosis I took this in conjunction with Femara. I experienced abdominal pain, water gain (about 12 lbs, all in the abdomen), and dizziness. I didn't like it. It didn't help with endo pain, and the drug itself was a pain. F 24 14 days
1X day
12/14/2012
 3  endo heavy bleeding. crying, headaches, tried, feeling afraid. This medicine made my ovaries hurt. I do have a 2 inch centimeter cyst on my left ovary. I'm praying that I don't have to have a DNC in the next couple weeks because I'm still on. a lot of frequent cramps bleeding constantly. 38 2 weeks
5mg
9/12/2012
 3  Endometriosis, Fibroids, cysts Depression, breakthrough bleeding, Melasma, weight gain, Sleeplessness, night sweats, Deciduous Cast, hot flashes A lot of bleeding and cramping the first few months. Slowly upped the dosage to 15 mg a day, whenever we upped the dose, I would bleed and once had a decidous cast (so painful!). Now that I have been on it a few months and the dosage is stable.. I have reaches amenorea and am not bleeding at all. Weight gain, sleeping issues and depression are the worst side effects for me. But this drug has stopped the pain associated with endometriosis and has shrunk my ovarian cysts. I will stick with this drug despite the side effects for now, because the other options (lupron, surgery) have worst effects. F 38 4 months
5 mg 3X day
8/20/2012
 2  Fibroids/Endometriosis Night Sweats, Mood Swings, Irrability The pill stopped my bleeding right away. I took Aygestin in comb/w Lupron 3 month injection. I had "break through" bleeding after one month on the medication, it was light to where I could where a panty liner. That started June 5, 2012, I had a laproscopic myomectomy on July 9th my bleeding never stopped for the 5 weeks leading up to surgery. The lupron has run it's 3 month course and I stopped Aygestin on Aug 5, 2012 and I am STILL BLEEDING. I esentially have been bleeding/spotting for 2 months. My doctor says it's normal, but there is nothing normal about bleeding for 2 months. I read it can take up to 2 months after you stop taking aygestin for it to leave your system. So does that mean I will bleed for another 2 months a total of 4 months non-stop and then I have my period to look forward too. I will NEVER take this agan!!! F 32 3 months
5 MG 1X day
8/17/2012
 2  45 day period from fibroids/polyps weight gain irritable acne I hade a 45 day period with extremely large clots, heavy flow and painfl cramping. Aftrer 2 ER trips and 4 trips to pcp, and three different estrogen hormones, I finally had an ltrasound revealing large polyps/fibroids. Taking 10 mg/day for a week didnt not stop bleeding or change cramping/clots. I am now taking 10mg in AM and PM.I had break through bleeding every day. Recently, incredible pain/volume/clots returned despite 20mg/day. I have to have a hysteroscopy and then a d&c. I want them to jst take it out. I have no insurance. $112 out of pocket for one med is rediculous. F 37 5 weeks
10 MG 2X day
8/13/2012
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 2  To regulate period The first couple days I noticed that I was very bloated and so bloated that it hurt my feet walking. I gained 6 lbs within the first 4-5 days. I also started breaking out and I look like a high school student with bad acne right now :( I couldn't sleep well and started having some crazy dreams. NO sex drive whatsoever and random cramping as if I were going to start my period. As soon as I noticed the weight gain, I started drinking water like crazy, eating healthier choices and continued my normal exercise routine. The weight was controllable. My other side effects remained the same but the acne worsened. F 25 3 weeks
5 2X day
8/1/2012
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 4  Heavy Bleeding and clots Bloating, extreme increase in sex drive, shakes initially Very thankful that this medicine stopped my bleeding. I was soaking 3-4 pads per hour. I was able to finish my Masters Degree without worrying about bleeding through while in class F 41 20 days
10 mg 2X day
7/11/2012
 1  abnormal heavy bleeding Extreme abdominal tenderness and (searing),tearing pain with movement as if guts could bust and fall out ,extended up the sides of ribs hard to wear bra from pain even ,extreme bloating heavy feeling , 25lb wieght gain in 3wks.,swelled legs and calves painful to touch ,loss of appetite, nausea,Moody,Cry at nothing . F 40 2 weeks
.5 mg 2x d
7/5/2012
 4  Abnormal Periods My sex drive increased while taking this medication. I would often have several oragasims throughout the night to the point that it would wake me up out of my sleep. My cycle regulated itself and I am now back to normal. F 34 12 days
5mg 1X day
6/14/2012
 4  bleeding for several months major weight gain, alittle acne, tired all the time and a headache every day F 47 14 days
5mg 2X day
5/30/2012

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