REGLAN Reviews (METOCLOPRAMIDE HYDROCHLORIDE)

Average Rating: 1.4 (649 Ratings)

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 DISORDERS, ACID PEPTIC

 Type: Rx Drug

  

REGLAN  (METOCLOPRAMIDE HYDROCHLORIDE):  This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for persistent heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime. Treating persistent heartburn can decrease the damage done by stomach acid to the swallowing tube (esophagus) and help healing. Metoclopramide is also used in diabetic patients who have poor emptying of their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines. This drug is not recommended for use in children due to an increased risk of serious side effects (such as muscle spasms/uncontrolled muscle movements). Ask the doctor or pharmacist for details.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR REGLANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  delayed gastric emptying extreme restlessness, severe depression, nervousness, anxiety, sleeplessness, inability to be still I would not recommend taking this drug. I took Reglan for two weeks until the side effects became so severe. After not taking this med for a week, I am still experiencing the same degree of side effects. How long will it take to get back to normal? M 22 2 weeks
1/19/2009
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 1  to increase milk production Extreme restlessness, unable to sleep, severe anxiety, stiffness in jaw, constant need to move; fear of being alone Took three doses (10 mg each) before symptoms began. F 28 1 days
1/16/2009
 1  GERD/Bile reflux nervousness, feeling of paranoia, hands tingling, dizziness, blurred vision, jittery/insomnia but very tired at the same time I have been on PPIs for GERD for about a month. During this time, I've taken metoclopramide a few times and had terrible side effects (starting within hours of taking it). If I stop the metoclopramide, the symptoms go away after 1-2 days, so I believe there is something about the combination of the drugs that increases the side effects of the metoclopramide. I have taken metoclopramide on its own before and not had any side effects. Suffice it to say, that I will be throwing the metoclopramide in the trash and trying some other therapies (including homeopathy - honey/acv, digestive enzymes, etc) that seem to work better than even the PPIs F 33 3 times
1/16/2009
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 1  Acid Reflux Within the first few hours of taking the first dose I experienced anxiety, agitation, jitteriness, while at the same time feeling exhausted. I also got a "pins & needles" feeling in my arms & legs, which later developed into severe muscle cramps. I actually thought I was dying. I only took Reglan for one day & that was it. This was about 8 years ago. I called my doctor at the time while experiencing all those horrible side effects, & he acted all suprised, & said that the Reglan shouldn't be causing all that. A few days later I asked my primary care physician about Reglan, & he responded with the statement "it will mess you up". Then he said something about Reglan effecting the "blood-brain barrier", & that's why it makes some people feel so horrible. When I had to have my gallbladder taken out last year, the nurses mentioned that they would be giving me Reglan, & I freaked out. They said not to worry, because they wouldn't give it to me until they also gave me the medication to relax me, & it would be right before they took me into surgery. They said they used to give it to people earlier, but had to stop because people would get anxious & just get up & leave the hospital. So now they only admini F 29 1 days
1/16/2009
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 1  Increase Milk Supply Severe anxiety, nausea, diarrhea, tension, feelings of unease I took Reglan to help increase my milk supply. The dosage was a gradual increase, peak, then decrease. When I tapered off the medication is when I started getting the nausea and diarrhea - then the feelings of anxiety set in. I do NOT have a history of anxiety so I was very freaked out. My arms would start to warm and tingle and then the anxiety and nausea would kick in. I thought I was going crazy. I wasn't comfortable in my own skin. My OB/GYN chalked it up to post-partum anxiety/depression. But, I searched and found that some people do experience withdrawl issues with Reglan. I confirmed with the pharmasist. I got an rx for Xanex and that got me through the worst of it. Took about 6 weeks to completely get over the withdrawl symptoms. F 38 25 days
1/12/2009
 1  bowel movement after surgery Extreme agitation, pacing, panic, sheer terror, suicidal thoughts. This medication was given to me after a routine appendectomy. I just needed to have a bm to go home. I can't even describe how my life was changed afterward. I paced for hours, I was in a place I didn't know my mind could go. I was up all night in sheer terror. They kept administering valium and meds to try and get me to calm down but to no avail. My body was physically tired but my mind was racing and it just made it worse. I hadn't had a panic attack before this. I ended up quitting my job because I couldn't feel "normal". It was about 9 months to a year before I felt normal again. I had to take Paxil and Xanax. I took one dose of this drug 14 years ago and it changed my life. I just decided to look up and see if it was still being taken and if there was any comments about it. I can't believe I found all these comments! It wasn't just me! Totally shocked that this is still on the market!!!! F 40 1 days
12/25/2008
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 2  migraine Extreme jumpiness. It is hard to describe but I felt like I had to get up and leave. Despite being in severe pain I felt like coming to the ER was a mistake. I felt like I had to go. I was very uneasy and it was impossible to get comfortable. Reglan/Benadryl combo might work for a migraine but I will not take it again. F 22 1 days
12/23/2008
 5  constipation None I love this medication. I've had a subtotal colectomy, but still needed some help as I had slow transit. This allows me to go to the bathroom, but does not make me rush to the bathroom like laxatives do. F 41 2 years
12/18/2008
 1  gastroparesis i have depression the ILLNESS and am medicated for it, as well as for an anxiety disorder. Reglan made these problems a thousand times WORSE...suicidal thoughts, which i had not experienced since being tried on Topamax for chronic pain. VERY emotionally labile...horrible...so i stopped taking it four times a day, dropping down to once a day. it blew my MIND when i called and talked with the GI doc who prescribed it. he was surprised to hear of my bad reaction. had NO IDEA ....well gee Doc, right there in the pamphlet that comes with this nasty drug it says "DRUG SHOULD NOT BE ADMINISTERED TO PEOPLE WHO SUFFER FROM DEPRESSION" yeah, trust your doctors. right. did it help the gastroparesis? i couldnt' say. i guess it did for awhile....but how do you explain the fact that when i stopped taking it four times a day because of the negative side effects, my body was suddenly quite capable of having my stomach empty properly? was it that the Reglan WORKED ITS MAGIC?, in just a few weeks, or....was this a problem that just naturally righted itself? F 56 4 weeks
12/3/2008
 1  Gastroparesis Extreme depression and Anxiety. Suicidal thoughts, restlessness, agitation After being on Reglan for about 7or 8 weeks, I became very drepression and extremely anxious. I began to have suicidal thoguths and stopped taking it. I have been off it 8 days. I no longer have suicidal thoguths and my depression has lifted, but I still feel very anxious and restless. Have to walk around alot and my mind gravitates toward worrisome topics M 41 8 weeks
11/30/2008
 1  stomach cramps, slow digestion Severe anxiety, depression, suicidal thoughts. If anyone of you are experiencing any of the symptoms that I had, stop the medicine immediately, but relax. For anyone interested in knowing when the side effects wear off, it could be up to a year to feel "normal." M 19 3 weeks
11/30/2008
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 1  gerd severe depression, panic attacks, shaking in the hands , afraid to go out in public, crying, feelings of wothlessness. I am now on an antidepressent and additional medicine for panic attacks. I took over a period of 12 months and was never told not to take after the 12 weeks recommended time period. My doctor told me he had no complaints but the pharamacist told me that the side effects are common. I was also told to continue the reglan by my GI specialist and she never mentioned side effects. F 63 9 months
11/17/2008
 1  to increase breastmilk production depression, anxiety, panic attacks, insomnia, rapid heartbeat, fatigue, extreme sleepiness I was willing to deal with the depression/ anxiety and extreme sleepiness because my baby would not take a bottle and when I would stop taking Reglan he would start loosing weight, but now I have developed insomnia/ rapid heartbeat/ panic attacks that have gone on for about a week and I can no longer take this drug. This has never happened to me before and I feel like I drank about a gallon of coffee though I haven't had any caffeine. Luckily my baby just started taking liquids from a cup so I can finally stop taking Reglan. F 31 11 months
11/12/2008
 1  knee surgery pre- & post-op akathisia-terrible anxiety, fear, hopelessness, inability to sit still, overwhelming fatigue, horrible urge to constantly pace, racing heart, tight jaw...felt like I was going crazy. After only a few doses, the symptoms continued to worsen over two weeks until I was given a Valium. That stopped the worsening but it took about a month to feel completely myself again and about a year to FORGET the horrible anxiety that had gripped me. I had my appendix out several years later and I wrote NO REGLAN in black marker next to my IV port! Had no problems at all that time. THIS IS TRULY POISON! As the pre-op IV Reglan was going into my vein, I felt my jaw tighten & was seized with the urge to get up & run. On waking up from surgery, I was given two more IV doses for nausea, accompanied by horrible anxiety/fear & the urge to run each time. Over the next 2 weeks, all these symptoms worsened, even though I took no further Reglan. All I could do was pace & sleep. Amazingly, the surgeon, the anesthesiologist, and the ER doctor I finally had to see did NOT know that Reglan could cause these effects. They all thought I was a hysterical female. I figured it out myself after requesting my hospital records & researching every drug that was administered to me during surgery. I have the advantage of being a neurologist's asst, so I had many resources. Finally, my primary MD gave me a Valium and for the first time in 2 weeks, I was able to get a grip on myself. Look in the PDR. The warnings & side effects for Reglan are terrifying, yet F 59 1 days
11/6/2008
 5  GERD/Barretts Esophagus None I have suffered from severe reflux for over 20 years. Years ago I took another drug similar to Reglan (propulsid) that worked wonderfully well, but it was taken off the market due to complications with heart attacks. My doctor put me on reglan three weeks ago for a 4 week trial to see if it helped. In that time I have only had one episode of reflux and, to be honest, I probably deserved it since I ate very, very spicy food just to see if the reglan would work in extreme situations. Note that even though I refluxed, it wasn't as severe as it usually was. Overall, I would say reglan has worked extremely well for me. My doctor explained in great detail the potential risks and I decided to try it rather than have surgery since I'm all about less invasive procedures when possible. I'm sorry to hear about everyone else who has problems with it. For me it's great so far, although I haven't been on it that long. I'm supposed to take 10 mg before each meal and at bedtime, but I don't eat breakf M 56 21 days
10/17/2008
 3  GERD breakthrough It seems to be causing night-time restlessness and I can hear my vascular system thumping away, so it must be causing some anxiety. Nothing as bad as these others indicate, however. Reading these others' comments convinces me it is the Reglan causing these symptoms and not some other cause. It does help with the severe "breakthrough" I was experiencing due to a hiatal hernia. It moves one's food from the stomach more rapidly, and it was explained to me that the food "lingering" in the stomach causes a lot of the acid reflux/breakthrough. I was taking Reglan in addition to Nexium and/or Zegred. M 54 3 weeks
10/12/2008
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 1  increase milk production depression, severe anxiety, panic attacks, tingling/burning sensations in arms, restlessness I took reglan 10mg (anywhere from 1 to 3 times a day) for about 3 1/2 months to increase my milk production. About a month ago (while on the Reglan), I noticed that I was becoming depressed and anxious and didn't know why. 12 days ago I realized that these were side effects of the reglan and discontinued it abruptly. I had already visited my PCP for the anxiety/depression and was given Lexapro. I had not started it. Two days after stopping the reglan, I experienced a severe panic attack, so I began taking the Lexapro. For the next two days, I felt very empty inside and could barely get off of the sofa. I was unable to care for my children. On Monday and Tuesday, I had severe panic attacks that lasted almost all day and improved in the evening. Wednesday was a little better, but still horrible. I spoke with my boss who is a physician and we dicussed the mechanisms of reglan withdrawal. The axis of your brain that deals with dopamine and acetylcholine becomes imbalanced and needs F 26 3 months
10/10/2008
 1  Increase Milk Supply Extreme fatigue, anxiety, weepy, feeling unable to cope with my newborn, not myself, feeling "mental" I was only on Reglan for 21/2 days before I realized that my severe anxiety, weepiness, and other side effects must be caused by the drug. I stopped taking it immediately and now feel much better. I would not recommend this drug at all. The negative effects can sneak up on you and it can be hard for new moms to tell if anxiety, depression and sleepiness are the drug or just normal post partum hormones. I was fotunate to realize that the feelings I was having were way out of wack and stopped taking the drug. F 38 2 days
10/7/2008
 4  Nausea (Food Poisoning) Tiredness/Drowsiness Well done. I am allergic to Compazine so I take Reglan instead. Frankly I think the 1 ratings are all from one or two people repeating themselves. M 29 20 times
9/26/2008
 1  GERD, Delay Gast. Empt., Aspiration Severe Fatigue over and above the fatigue I already had. Lethargy, occasional dizziness, intestinal gas extraordinaire, Depression I thought I'd dealt with on anti-depressants I just found out today that Reglan can cause drowsiness and fatigue! I am angry that my Dr. never told me. I've been on 40 mg. 10mg/4xday on and off for years. I went back on faithfully about 6-8 months ago and wondered why I'd suddenly become so depressed and fatigue which I expect hung on forever. It was all consuming and has taken my life away. I have Sys. Sclerosis which causes many problems in addition to motility disorders so my life is hard enough without feeling like I'm under a truck! F 54 8 months
9/17/2008
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