REGLAN Reviews (METOCLOPRAMIDE HYDROCHLORIDE)

Average Rating: 1.4 (649 Ratings)

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 Type: Rx Drug

  

REGLAN  (METOCLOPRAMIDE HYDROCHLORIDE):  This medication is used to treat certain conditions of the stomach and intestines. Metoclopramide is used as a short-term treatment (4 to 12 weeks) for persistent heartburn when the usual medicines do not work well enough. It is used mostly for heartburn that occurs after a meal or during the daytime. Treating persistent heartburn can decrease the damage done by stomach acid to the swallowing tube (esophagus) and help healing. Metoclopramide is also used in diabetic patients who have poor emptying of their stomachs (gastroparesis). Treating gastroparesis can decrease symptoms of nausea, vomiting, and stomach/abdominal fullness. Metoclopramide works by blocking a natural substance (dopamine). It speeds up stomach emptying and movement of the upper intestines. This drug is not recommended for use in children due to an increased risk of serious side effects (such as muscle spasms/uncontrolled muscle movements). Ask the doctor or pharmacist for details.    (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR REGLANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  acid reflux I took this drug in 2007 and wanted to update my experiences with Reglan. Side effects - life long tremors, involuntary muscle spasms, akathisia, severe anxiety and Tardive dyskinesia. Under any circumstances, please do NOT take this medication. It has literally ruined my life. I am a young woman who is damaged for the rest of my life because of Reglan. This drug blocks dompamine from your brain. Dopamine is a neurotransmitter located in our Central Nervous System making it one of our most important neurotransmitters. Without dopamine, you can develop neurological conditions, suicidal ideations and behavioral problems. This drug should be banned. If you do take this drug, DO NOT take this drug for more than 3 months, as it's only approved by the FDA for 3 months. I was left on the drug for 6 months and my brain became damaged. I will never be the same person, thanks to Reglan. F 37 6 months
11/12/2009
 1  Nausea from high blood pressure Took this drug in 2007. Unable to balance well when walking; tend to drift to one side. Occasionally use a walking cane for support. Currently (2009) in my third round of physical therapy. Numbness in left side of face and tongue; lost taste sensation, can only distinguish hot vs. cold food. Supposedly a drug is approved because the benefits outweigh the side effects; how did Reglan get approved? Allowing this drug to destroy so many people's quality of life is criminal. F 82 3 months
11/11/2009
 1  increase breastmilk supply sudden onset of uncontrollable crying, depression, anxiety, panic attacks, insomnia, suicidal ideations There is hope for those experiencing these horrible side effects from reglan! I was terrified that the reglan had permenantly damaged my brain and really suffered for about 5 weeks. I am almost seven weeks out from the onset of the symptoms and am feeling MUCH better and pretty much back to myself. I was prescribed Ambien CR for the insomnia and am still using it for now as my sleep is not quite back to normal yet. I was prescribed valium for the anxiety but didn't start on an antidepressant as the psychiatrist felt like things would level out within a couple of months. She was right. Just keep praying and know that God is with you throughout the worst of it and that you will get better! F 35 10 weeks
10/28/2009
 1  Increase breast milk production Anxiety, shortness of breath Reglan was prescribed to me in order to increase breast milk production, and it only made a difference by a couple of ounces. Not worth the anxiety it caused. It made me feel horrible and almost panicky. and it also made one breast produce more than the other so they were completely uneven. Staying far away from this stuff. F 29 10 days
10/24/2009
 1  slow digestion fatigue, depression, anxiety, severe pain under right rib cage. Has anyone had a diagnosis of Biliary Diskenesia since taking Reglan. I have been recently diagnosed with BD and advised to have my gallbladder removed. I just read online a link between Reglan like drugs and BD. Has anyone had their gb removed because of bd and did symptoms improve after? F 45 7.5 months
10/22/2009
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 1  upset stomach I was given an injection for extreme gas pains while in hospital. 45 seconds after the injection I jumped from the hospital bed and began trying to rip my head open.It felt as if I had something on the inside of my head wanting to get out. I ran around the bed trying to get my brains out, and then I jumped back into bed and locked my arms around the bed rails and cried myself to sleep praying to god. After my wife got the nurse back in the room I was sleeping. The Nurse told my wife that I was one of few who were allergic to the Drug Reglan and that all medical personnel was told of this side effect, but they had never had any one who was allergic. She also stated that she wish she was able to see it happen, because I was the first. Now I see that I’m not the only one. M 39 1 days
10/16/2009
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 1  Gastroparesis Was prescribed reglan in March 2007 and began suffering from severe anxiety and depression in September (at least, that is when it became very noticeable). Began seeing a psychiatrist who prescribed Lexapro (depression) and clonopin (anxiety). My gastroenterologist substituted domperidone for the reglan in October and some of the anxiety and depression symptoms began to subside. However, the Lexapro and clonopin began contributing to symptoms of there own and I was advised that, having an addictive personality, I might want to discontinue these drugs. This is not as easy as just quitting; however, I lucked onto a website that helped me gradually wean myself from these drugs. Today, I no longer take presciption medications and have adopted an eating plan that includes a regime referred to as proper "food combining". This, coupled with probiotics which are known to decrease anxiety and depression, has helped me return to a fairly normal life. I cannot overemphasize the importan M 65 219 days
10/12/2009
 1  Gastroperiesis Depression, Suicidal thoughts, Severe Anxiety I posted on this forum about one year ago after having been on Reglan for about 8 weeks. The effects of the medication were one of the most significant things that has ever happened to me in my life. I was truly suicidal and beginning to formulate a plan to kill myself. Thank god something in the back of my mind told me what was happening to me was an effect of the Reglan. I stopped the medication and after a few days I felt the depression lift somewhat and the Suicidal thoughts went away. It took considerably longer for the anxiety to lift. For weeks I was worried, anxious and just not feeling right. Several doctors I spoke to want to put me on a variety of psychiatric drugs, but I wanted to see if things would correct by themselves. For the first two weeks after I stopped, I found Benadryl effective a dampening my anxiety. After two weeks I found, I didn’t need it anymore, but cut caffeine out of my life altogether, because I found I could not tolerate the ‘agitated’ effect caffeinated coffee or tea gave me. This forum was a god send for me. During the first few weeks I found myself pouring over the entries. I found it so comforting that I wasn’t crazy; it was a bad reaction to a medication. I found it took about 60 or so days for me to feel fully back to normal. If you are going through this, just remember, it gets better M 42 8 weeks
10/10/2009
 3  Gastroparesis Anxiety, hand tremors, nervesness, can't seem to sit still. I was only on Reglan about one month and then Gastro Dr. took me off the Reglan and started me on Amitiza, which has been helping I believe Reglan did help, but my side affects are still with me two months later. F 61 30 days
10/6/2009
 1  gastroparesis problems staying asleep then not sleeping at all, depression, suicidal thoughts, anxiety, loneliness I took this med for about 2 months. After a month I started having problems staying asleep. Then I could barely sleep at all during the last month I took it. During the last days of the two month period I started vomiting and having suicidal thoughts. I took myself to the hospital. I called my mom and started to cry. Then I finally saw the nurse and told him about the vomiting. I then said that I thought I was depressed and immediately started to cry again. Then I cried again with the psychiatrist. I was given anti-depressants but they didn't say anything about the reglan. I made the connection myself after reading the side effects in the med info and stopped taking reglan. After 1 week I was no longer depressed but still have anxiety. I stopped taking the anti-depressants after that first week. After 4 weeks I still have anxiety but it seems to be wearing off. The back of my head and neck seem to be tense. I might go back to taking the antidepressants to see if it helps with the anxiety. I will post back again later on for an update. M 26 2 months
10/6/2009
 1  migraine nausea etc panic attack, unpleasant drowsiness and anxiety I have had a major reaction to prozac (went quite crazy after 18 days ) which was prescribed to help migraines, and have also reacted to maxalt. Seems I have a sensitive brain! Was prescribed to reglan to help absorb painkillers for the migraines .. and after a few days use had a panic attack and de-realisation episode shortly after taking it with painkillers, (in the supermarket- yowwza!!)and realised it had gradually been making feel strange. Not as bad as the prozac episode, and I used CBT techniques and recovered quite quickly. Still very unpleasant however. F 40 7 days
10/5/2009
 1  Increase Breastmilk Production Severe anxiety, depression, jittery, nervousness, skin crawling There is hope... If you are experiencing/experienced depression and anxiety from this drug it doesn't have to be permanent. I was on Reglan for 30 days to increase breastmilk production. By the end of the 30 days, I started to feel some depression. I stopped the drug and within 3 days experienced severe anxiety/nervousness. I went to the dr. and was prescribed Lexapro (anti-depressant) and Xanax (anti-anxiety). After being on the anit-depressant for 2 weeks I felt MUCH better. I no longer need the anti-anxiety but will continue to take the anti-depressant until my dr. says I can ween off of it. My aunt is experiencing the EXACT same thing, she was on Reglan for 2 months and is now taking an anti-depressant and anti-anxiety drug. F 33 30 days
10/2/2009
 3  Increase Milk Production I did not experience any side effects I took 10mg 2x day and did have a mild increase in milk production. F 33 30 days
9/22/2009
 5  Irritable bowel syndrome I had no side effects F 54 5 years
9/21/2009
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 2  gastroparesis Breathing issues, anxiety, nervousness, sleeplessness, tremors. Can not function. I had been taking Reglan for about 3 months. Its has changed the way I have been living. It would work for the Gastroparesis 3 out 7 days of the week. Reglan would get me worked up enough emotionally ( in which I ve never been before in such a matter) that I would heave, throw up. I just came of the reglan last week and the symtoms increase 3 fold. I couldn't breath on Friday and had to go the the er. I drove in that conditon. If you can I recommend you avoid this drug. There are two more medications out there that help. One is Euthomysine(sp) and the other is Domperidone ( its approved everywhere except for the US)The side effects are still affecting me and I m taking three types of Anxity meds in which I ve never had to take before. If any one from OEF or OIF (Afghanistan or Iraq) that has been affected by gastroparesis please let me know. M 39 3 months
9/6/2009
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 1  increase milk production shakiness, drowsiness, insomnia, depression; withdrawal--anxiety attacks, severe insomnia, skin crawling, inability to sit still Worked like a charm to increase my milk production, but not worth it! While taking the medication, the side effects were livable, but after going cold turkey I thought I was going to die or lose my mind. My doctor put me back on the reglan at a lower dose and tapered off, which helped the anxiety, and put me on Lexapro. I took Xanax and benadryl to help me sleep--not very effective, but better than nothing. Now I'm on Ambien, which helps sometimes. All the anxiety symptoms are much better after 4 weeks. Still having major trouble with sleep though. F 10 weeks
9/3/2009
 3  Migraine I had an extreme anxiety attack within minutes after receiving 10mg of Reglan IV. I felt like a was going to stop breathing and could not stop crying and screaming for help. It stopped after 5 minutes when the IV Benadryl kicked in. I would recommend having Benadryl given and then Reglan instead of vice versa. After I recovered from the anxiety attack, my migraine did go away. My chest is still heavy and I still feel jittery. F 23 1 days
9/2/2009
 1  Gastroparesis Skin crawling, can't sit still, anxiety, profound desire to sleep, loss of interest. Thank you for this website and thanks to everyone who shared their experiences. I am in tears, mostly of gratitude, to know I am not crazy. I've been trying to explain how I feel to my husband and I know he doesn't understand... F 42 6 months
8/22/2009
 1  Increase Milk Production despondence, flat hopeless affect My wife was on this for months. It got to the point where I didn't know who I was married to anymore. She cared about our child and making sure he was adequately supplied while nursing, but at the same time she lost all interest and care about anything else. She wanted to give up, throw our jobs and friends away and move. There was moodiness but mostly she was totally disengaged all the time. People who new her were on eggshells around her. I witnessed many of the psychological symptoms described by others, but the most detrimental was the denial. The negative effects of this drug were an unnoticeable slow buildup. For a long time we dismissed these feelings as part of being a new mom. It got the the point where I could see signs of dependency and I sought help for us. Our marriage was suffering and our child was able to get adequate nutrition without having to nurse as much. Since stopping the medication our communication has been restored and she is able to once again laugh and smile genuinely. She's like she was before. This drug isn't worth it. The denial and change in demeanor is noticeable by family, friends, and colleagues and it can cause long term detriment to relationships and careers. Not to mention, there is a class action suit now being brought against the makers related to onset of Tardive Dyskinesia, which is irreversible. M 31 8 months
8/18/2009
 1  migraine right after the nurse injected this in my iv, i just felt this lighheadness, and i just started freaking out feeling like i couldnt be comforted at all by anything: i demanded to go home over and over and over and over: the nurses rushed into the room and asked me if i was feeling like i was crawling out of my skin, i was crying and twitching so bad that i nodded yes and she ordered more benadryl to be injected in. I was supposed to have a ultrasound, but I demanded to stop treatment so i could recover at home from the reglan (this has happened before and the doctors didnt do anything about me twitching and having a anxiety attack!!!) I slept it off and I now cannot sleep due to the side effects. dont ever take this. Its not worth it. The skin crawling experience occurs in about 1 out of every 1000 patients. It just was the most traumatic experience. F 20 4 times
8/10/2009

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