SYNTHROID Reviews (LEVOTHYROXINE SODIUM)

Average Rating: 2.6 (900 Ratings)

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 THYROID ANTITHYROID

 Type: Rx Drug

  

SYNTHROID  (LEVOTHYROXINE SODIUM):  Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer). This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.   FDA Approval Date: 2002-07-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SYNTHROID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SYNTHROIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  hypothyroid I've gained 30 lbs while eating moderately and faithfully taking three 1-hour exercise classes per week at my gym for three years. I also have joint pain in my fingers. Shortly after starting this med, symptoms disappeared! I was no longer cold, I no longer needed sudden, urgent naps in the afternoon, and my menstrual cycle returned to normal (was very heavy and every two weeks). My T3 and T4 levels have been regulated. F 39 3 years
12/28/2009
Email
 3  Hypothyroidism Insomnia, mild muscle cramps, headaches, extreme confusion I was started on Levothyroxine (generic) when first diagnosed. After 1 week, I experienced headaches, forgetfulness and felt like I had gained weight on either side of my neck. My doctor took me off for one week and reintroduced Synthroid at the lowest dose. I've been on it for 3 weeks and will retest to see how it is doing. So far I am experiencing extreme insomnia, extreme memory loss, occassional headaches, experiencing dry skin again, mild muscle cramps and occassional fatigue. It may either be an allergic reaction or not enough dosage. The medicine has helped with the extreme fatigue, regulation of monthly cycles (with the help of birth control) and at first, dry skin. I'm not sure that losing my memory is a good trade off at this point, but will continue to work with the doctor or perhaps see an Endo. It is hereditary in my family and at the suggestion of my brother will have my hormones (estrogen and progesterone) checked along with the T3 and T4. F 41 3 weeks
12/30/2009
Email
 3  Had a total Thyroidectomy June 09 Hair Loss(still),weight gain almost 70lbs in a year and half due to Hyperthyroid and Graves Disease.I am still fatigued - dont sleep well - continual headaches and continual menstrual cycle for 20 days out of the month for the last 3 months. Really dont have an urge to eat. Just tired all the dang time and really feel like I am at my witts end. F 38 180 days
1/19/2010
Email
 3  Total thyroidectomy on January 2,20 F 52 2 years
0.075mg 1X day
5/21/2017
Email
 3  Hypothyroidism Increased anxiety and too stimulating for me. I am anxious to begin with. It got my TSH levels at normal levels after 6 weeks, but by week 6 my anxiety and stimulation on it was too much for me to handle, so I went off it. I guess I am sensitive to it. F 34 6 weeks
25 mcg 1X day
7/7/2017
Email
 3  No thyroid Don't really have any I take 75mg I was taking it half in morning and half in after noon my tsh was 3.25 2 months later got my tsh done it went up to 9.75 not sure why F 54 2 months
75mg
8/31/2019
Email
 3  Hypothyroid Weight gan, cant loose no matter the diet or exercise. Brain fog and Extreme stiffness in hip muscles and joint. Past two years the pain and stiffness in my legs keeps getting worst. I cant walk without pain. Drs. Cant explain it. Something is off. Not sure what to do. F 57 19 years
125 1X day
9/15/2020
 3  Hashimoto Disease Eye Twitching, Lip Tingling, Dry eyes, weight gain, anxiety, panic attacks, constipation, dry skin, hair falling out. Synthroid in low dosage seems to work for me, but then my blood levels are not good. When the doctors increase the dose to 88 mcg, I have all of the side effects listed above. F 57 17 years
88mcg 1X day
10/13/2020
Email
 3  No thyroid Tired dizziness no energy F 55 2 weeks
50mg 1X day
11/21/2020
 3  Hypothyroid and Hashimotos Weight loss, depression, severe anxiety, mood swings I can't complain I've lsot weight while on synthroid. I work out 5 days a week and eat well. However I've been an emotional wreck. Crying constantly, contemplating suicide. It has gotten so bad that it is affecting my relationship with my boyfriend and parents. I am considering a natural route. F 25 1 months
100 mcg 1X day
7/13/2015
Email
 3  TOTAL thyroidectomy Hair loss, moodiness, sleeping too much, sleeping too little, racing thoughts, pain in hands, knees, ankles, irritated my inflammatory response, acne, anger, mood swings I had a total thyroidectomy on february 20. I was put on synthroid at 88mg. One month later i had my tsh levels tested and was 25tsh. They upped my dose in april to 112 and my tsh went to 12.5. Then in june they upped it to 150mg and now my tsh is at .4. This is to suppress the cancer cells in the papillary cancer which was removed. I still have medullary thyroid cancer cells in my neck, left over from the surgery. Please tell me this gets better. F 41 5 months
150mg 1X day
7/27/2015
Email
 3  Hypo-thyroid Only been on it two days but I am starting to feel like myself again Had symptoms of fatigue for a year after a long illness. It was discovered that my pulse had slowed to 40-50 beats per minute down from 62-68 my normal. I've had my thyroid checked many times over the years b/c of other symptoms ie hair loss, missed periods, but it always came back low-normal my lastest doctor suggested depression UH DUD I'm exhasted all the time yes I'm upset. Final I went to an Endo. DR. a panel showed a low t4 and high TSH. I'm hoping to wake up enough to enjoy my life. F 41 5 days
3/29/2008
 3  Hypothyroidism/now hyperthyroidism Stiffness in the hands, knee pains, NO libido whatsoever, mild depression, occasional headaches, fainting spells I started taking this medication 8 years ago for hypothyroidism and although it did help for my energy level and weight problem, my libido dropped extremely quickly and has never come back. I was diagnosed with hyperthyroidism 4 years ago and changed my dosage and that's when the stiffness and aches and pains kicked in. I also have frequent headaches and faint sometimes for no reason, which scares me cause it's already happened on the highway while I was driving alone (needless to say I hope never to live that again!). Now my husband and I are trying to have a baby and I'm really scared about miscariages. I've asked my doctor for alternatives but apparently this is the most efficient Canadian-approved drug for thyroid problems...plus I have to admit that my condition has been stable for the past 2 years but I hate the side effects. F 27 8 years
3/25/2008
 3  hypo still have depression, muscle pain, high cholesteral, weight gain, fatigue, brain fog still have all the symptoms even tho taking synthroid but doc says my blood levels are okay.... F 55 15 years
4/12/2008
 3  Hypo I never realized I was having all these sideeffects till now, for the past 20yrs, I have had constant weight gain, 65lbs in all, acid reflux, heart palpations, joint pain, mood swings. I was placed on this med, because of being tired all the time, at the time I was a new mom at age 25. I was told to take it, it would make a difference. When I noticed no difference, the dose was increased. I have to beg my GP for blood wk to see if all is going well, I'm always told, I'm in the nor range. I started to check out side effects. 7 months ago I decided it was time to take control of my mind and body, I hired a personal trainer to work with me 4 days a wk, 1-1 1/2 hrs, went on a strict diet, and never lost a lb. My husband has been telling me for the past 10yrs it's your synthroid, it's the only medication I take, and I think from all the comments I have read, that I need to make a drs app't. Problem were I live, is a doctor who is taking patients is very rare. I will be trying to get on a different medication, and will continue to read this board. F 46 20 years
1/6/2009
 3  hypothyroidism My hypothyroidism symptoms were so bad any improvement was well worth it. I had the symptoms and more. I noticed at first I had a racing and pounding heartbeat also sometimes short of breath. I did what my doctor said and stuck with it. Some days I would feel really bad. It was mostly horrible. I think it has helped some. I dont feel near as bad. I thought I was dying before so now I can live. My TSH was 5.5 and I have noticed that taking my synthroid at the EXACT same time everyday has made the difference of my life and how I feel.I mean at the EXACT same time and not a minute later. I mean I cant be 30 min to hour late or all my hypo symptoms return. I hope this helps some of u struggling. I know its bad but please talk to ur doctor. Im taking 50 mcgs and it has helped. I have been trying to eat healthier and add more iodine to my diet as well. F 26 4 weeks
1/20/2009
 3  Hypothyroid Stomache pains, headaches, aches and pains, nausea, diahreah I just started taking this medicine about 2 months ago and at first I felt great. I had a lot more energy and was very upbeat. I had some minor stomache pains but they didn't last long. Just this past weekend, however, I started having severe stomache pains, nausea, aches and pains all over, headaches, trouble sleeping and diahreah. I stopped taking the medicine 3 days ago and the doctor wants me to go in for more blood work. I am hoping this is only a temporary set back as I really enjoyed the extra energy I had when I started the medicine. F 42 2 months
1/6/2009
 3  Thyroid cancer/thyroidectomy Depression, fatigue, headaches, chills, constipation, low libido, weight gain, unable to concentrate. I was given my first dose of Synthroid in November 08, after I completed my radiation iodine treatment for papillary thyroid cancer. Was given 112mg and never really felt awesome, just in between. Some days were hard to get out of bed, others were not. Dr. upped my doseage after seeing my thyroid bloodwork levels weren't adequate enough. Have been on 137mg of Synthroid for about a week. My headaches are worse, I have cold chills, muscle aches, very low sex drive and a hard time concentrating. I've also been constipated for about two months now. I have yet to have the energy levels I had before I was diagnosed with thyroid cancer in September 08. I gained 40lbs in the past year and a half because of my thyroid issues and even with Synthroid, it's still really hard to lose. I will give my new doseage proper time for my body to adjust to it before I can make any statements about Synthroid, 137mg. F 22 60 days
1/6/2009
 3  thyroid removed tired all the time, cold all the time, irregular heart beats, mood swings, and weight gain I had my thyroid removed when I was 18 because I had cancer. Before my surgery I weighed 120 pounds and since taking synthroid I've gained 30 pounds and no matter how much I exercise and diet I can't get back to my original weight. Also, In the past 4 years I've been back and forth between 5 different dosages because they can't figure out which one works for me. I just wonder if anybody else has had as much trouble as me figuring out their dosages. I know that I need to take this, I'm just tired of having the way I feel by what dosage I'm on. F 22 4 years
12/16/2008
 3  Hashimoto's Thryoiditis None to speak of. Taking the generic form Levothyroxine. Except that I am usual quite regular with the monthly cycle and now I am not having one and I've only been on the meds for one month and this is the first period missed or prolonged in well over 7 years. I am unable to send an email to the female who submitted on 12/8/08 stating she has diarhea, and feels like dying, cold all the time. I had that. I also have exhausted adrenal glands and whenever I take the supplelemtns to help me with that, those symptoms and feelings go away. She should go to her doctor and get her adrenal function tested. Many Hashimoto's patients apparently can have adrenal problems also. Please tell your doctor to test you!!!!! Insist on it!!! F 51 35 days
12/18/2008
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