SYNTHROID Reviews (LEVOTHYROXINE SODIUM)

Average Rating: 2.6 (900 Ratings)

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 THYROID ANTITHYROID

 Type: Rx Drug

  

SYNTHROID  (LEVOTHYROXINE SODIUM):  Levothyroxine is used to treat an underactive thyroid (hypothyroidism). It replaces or provides more thyroid hormone, which is normally produced by the thyroid gland. Low thyroid hormone levels can occur naturally or when the thyroid gland is injured by radiation/medications or removed by surgery. Having enough thyroid hormone is important for maintaining normal mental and physical activity. In children, having enough thyroid hormone is important for normal mental and physical development. This medication is also used to treat other types of thyroid disorders (such as certain types of goiters, thyroid cancer). This medication should not be used to treat infertility unless it is caused by low thyroid hormone levels.   FDA Approval Date: 2002-07-24 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SYNTHROID: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SYNTHROIDCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  hypothyroidism Weight gain (slight), increased appetite, fatigue I was prescribed this (I have a TSH level of 7.5) and really felt wonderful for the first few weeks and then.... nothing. I still have many of the hypothyroid symptoms- low body temperature, low sex drive, cold hands and feet, etc. My doctor tells me that changes are so subtle that I will not notice the change day to day. After 4 months, I was hoping for something! F 30 4 months
10/18/2002
 2  hypothyroidism - always cold...to the point my home is at 80 degrees ( the average bear likes their home at 70 degrees ) and I am finally comfortable - complete exhaustion....could sleep life away - mood swings ... - dry skin..... I lose tons of hair every day, it is so bad I have to vacuum my bathroom every day. -headaches on regular basis I had a severely overactive thyroid as a child and docs didn't know what was wrong with me.At 8 years old a doctor finally figured out what the problem was ( and it was not tapeworms as most doctors thought back in the day lol ) Finally at 15 they did not want to give me radioactive iodine because I was so you young but they felt that my thyroid was so overactive and all the drugs known to mankind were not doing anoything they had to use radioactive iodine. Upon giving me the dosage did not get the results hoped for so a few months later they did another dose in Vancouver, B.C. then of course too much was destroyed and my whole life from then was overturned I have frozen my arse off since I was 16, gained a pile of weight, lost tons of hair, suffered depression, and am always fighting being tired. I have two boys 13 and 12 and I do a lot of pretending as I do not want them to worry or feel bad....but please if anyone has any ideas on what to do as I have been suffering with this for 20 years and all doctors tell me is quite often people still have side effects when on medication....I am on 112 mcg of synthroid a day. There has to be way more to life than this ......god help me I am sick of this..... F 35 20 years
1/5/2005
 2  hypothyroidism I don't know if I experienced any side effects from synthroid, or not, but I would prefer not to take it. I am on a very low dose since having my daughter 3 years ago. I experience anxiety at times and wonder if the synthroid is adding to this. One thing that has helped with this problem that I have discovered in the last year is something called Energy Medicine, or Energy Psychology. I had to open my mind to try this alternative new approach, but have had great results through exercises in a book by Fred Gallo, and Donna Eden. I encourage anyone with the same problem to give it a try. I did go to a practitioner who used this last year because I was going through a stressful time and had terrible eczema on my face for 3 months. I had tried everything to clear up the eczema and it went away literally overnight after my session. I hate taking drugs. Keep submitting your information about natural remedies. It is great for someone like me to hear about them. F 40 3 years
1/7/2005
 2  hypothyroidism 2nd day on a very low dosage, nassua, hot flashes, feverish, tired, hyper like, chest pains, just plain weird. 3rd time trying to take it and it still makes me very sick. I am going to stay away from it. F 35 2 days
5/25/2005
 2  Thyroidectomy extreme fatigue, limited energy, hair loss, joint pain, tooth pain (feel like they could fall out), gastro problems (3 months of appointments & colonoscopy & sigmoidoscopy to rule out Crohn's), just don't feel right, I would rather have lived with all the nodules in my thyroid & have it keep getting bigger than live like this. After reading up on Synthroid I have absolutely no idea why it's more commonly prescribed than any other medication. Have started with supplements and hope to change to Armour or Thyrolar at my next visit. I'm not a freak, but it almost seems like some kind of conspiracy that Synthroid is so prescribed! Be wary!!! F 35 1.5 years
2/8/2005
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 2  Thyroidectomy extreme fatigue, limited energy, hair loss, joint pain, tooth pain (feel like they could fall out), gastro problems (3 months of appointments & colonoscopy & sigmoidoscopy to rule out Crohn's), just don't feel right, I would rather have lived with all the nodules in my thyroid & have it keep getting bigger than live like this. After reading up on Synthroid I have absolutely no idea why it's more commonly prescribed than any other medication. Have started with supplements and hope to change to Armour or Thyrolar at my next visit. I'm not a freak, but it almost seems like some kind of conspiracy that Synthroid is so prescribed! Be wary!!! F 35 1.5 years
2/8/2005
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 2  complete thyroidectomy brain fog - couldn't make a decision, irritated alot, excessive sweating especially around head and neck had a left thyroidectomy 20 years ago due to a cold nodule - the surgeon then felt the whole left side needed to come out. Had the right side removed 90 days ago due to another cold nodule and a goiter, having pressure on throat, wheezing when sleeping. Went to an endocrinologist who had no empathy at all. Insisted I use Levoxyl - had a very bad stiff neck and headaches from that not to exclude the brain fog - I can handle most of the other symptoms but not that - I need to think clearly and couldn't. Then asked for Synthroid (he didn't want to put me on generic because he felt the dosage was too off). I stayed on that for a month before surgery and then for 1 month after surgery when I decided I needed to try something that would not give me the brain fog. Had been on generic before and didn't have problems from it. Called him, talked to his assistant (waste of time ) and he never called back. Talked to primary after that and she will prescribe but I do need to do the tests after a month. Will do. Brain Fog is gone , feel so much better. Anyone who has hypothyroid needs to get the book The Thyroid Diet by Mary Shomon. She will clear up what the doctors won't. Hope to eventually go on Armour after the blood tests. F 59 3 weeks
.125 1X day
8/13/2010
 2  Hashimotos some heart paplpitations and chest pains. Also have heart burn really bad which may be where the chest pains come from. Legs ache sometimes and have occasional headaches. Weight has pretty much stayed the same but I am in the weight range I should be in for my height anyway. The very beginning of Hashimotos was found in a blood test because I was going to the doctor due to sickness and fatigue. During this time it was found that my gall bladder needed to be removed. After having gall bladder surgery the sickness has gone away but these other symptoms have arised. I don't know if some of them are due to the gall bladder being gone or taking the Synthroid. The chest pains scare me but the doctor has done and EKG, Echocardiogram, and and excercise stress test and they all came back great. It must be the medication. F 40 6 months
50 mg 1X day
8/24/2010
 2  hypothyroid severe vascular right sided headaches daily feeling stroke like, ear problems dry eye dizziness bad allergies skin problems.. i am thinking this has to be from synthroid/cytomel after five years i have to figure this out?? too many posts sound like what i have been experiencing! i know it helps but it also hurts..i have to investigate how to get off i don't know what the alternative will be with all the troubles of natural thyroid shortage and reformulations? i also take cytomel.5mcg twice daily F 41 5.5 years
.88/1.00 1X day
4/26/2010
 2  hypothyroid weight gain!! switched to cytomel (generic) lost the weight and got the same desired TSH level F 57 1 years
100mg 1X day
6/20/2010
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 2  Hypothyroidism/Thyroidectomy Weight gain (25lbs total), dry eyes, blurred vision, ringing in ears, joint pain, dry skin, constipation, bloated, digestion issues, extreme fatigue, lack of concentration, extreme anxiety. Was originally on .50mg, then up to .75mg, then back down to .50mg when I insisted that my doctor supplment the Synthroid (T4) with Cytomel (T3) because my symptoms were getting worse even though he felt I was fine due to my TSH lab results. Doctor insisted the Cytomel wasn't going to help, but finally agreed to prescribe 5mcg Cytomel 2x/day. First 2 weeks were great and most of these symptoms disappeared, except for no results with weight loss. I was actually gaining again. So I decided to come off the Synthroid and stay on the Cytomel to see how I feel on that regime. It has been 5 days w/o Synthroid and just Cytomel. I feel great so far. I might have to convince my doctor to increase my Cytomel dose on the next visit, but anticipate a struggle as he didn't want to prescribe it in the first Having thryoid disease is a woman's curse. Even more frustrating is dealing with doctors who go off your lab results versus how one actually feels. And to top it off, they will tell you it's all in your head as you fight to feel human! Guess that is too much to ask for! If it were not for my tenancity and research into my health issues for over a decade, these doctors would have me on tons of different pills to treat symptoms -- not the problem itself. It is sad how widespread this thyroid issue really is and how many lives it can destroy as it affects your whole well-being. Keep searching for answers. Don't give up! F 43 3 years
.75mg 1X day
6/28/2010
 2  Hashimoto's Thyroiditis/Hypothyroid Anxiety, muscle weakness, shakiness, some tingling in hands and feet, additional fatigue and depression This is my second trial of Synthroid. For my first trial, I took generic levothyroxine (25 mcg) for approximately 3 weeks. Symptoms did not improve, muscle weakness was terrible, anxiety led to panic attacks, and toward the end of the first trial, I experienced extreme joint pain in hands and feet. Endocrinologist recommended that I try name brand Synthroid (starting on lower dose) because I may be sensitive to binding agent in generic brand and/or I may be sensitive to medication in general. So far, I have experienced similar symptoms (with less tingling in hands and feet), but anxiety, depression, fatigue are not going away. In fact, those three symptoms are worse than prior to both the first and second trials. If symptoms continue, I will stop taking medication, as Free T4 and T3 are still within normal range, but TSH was high at 7.8. I have signs of hypothyroidism and TPO antibodies are >1000, but Synthroid may not be the best choice for me. My next step will be to find an endocrinologist, Naturopath, or other to prescribe natural brand (e.g. Armour Thyroid). Many books and websites suggest that natural brands may work better for people with sensitivities/side effects from taking synthetic brands and/or T4 to T3 conversion issues because they contain both T4 (inactive) and T3 (active) thyroid hormones, in addition to other hormones (T2 and T1). F 31 5 days
12.5 mcg 1X day
6/29/2010
Email
 2  Hashimotos 20 years F 56
150 1X day
3/24/2010
 2  Hypothyroidism Extreme weight gain, poor sleeping habits, cold feet and hands, chilled body to name a few. This is a crazy drug. When they adjusted my dosage in the last year to 100mg, I lost 12 lbs in a week. When they re-adjusted it to a lower dosage, it was still too strong and now I am back where I started at 75mg. I gained 20 lbs in 2 months and no luck reducing even though my eatting habits have not changed. I have always been thin and gaining this amount of weight has put me in a mild depressive state. Also once you are on synthroid, you are always on synthroid and a lot of insurance companies are not paying for this prescription including mine. F 59 5 years
75 mg 1X day
2/10/2010
 2  Hypothyroidism Moodiness, anxiety, irritability, sudden bouts of fatigue, extreme memory loss, leg cramps, very sensitive to cold, itchy arms and legs, low libido, increased hunger, regained the weight lost with Levothyroxine. Positives include being able to sleep and less fatigued. Originally posted on 12/30/09 after an allergic reaction to levothyroxine, changed to 25 mg of Synthroid and then increased to 50 mg within when blood test showed still to low TSH (and experiencing moodiness, sudden bouts of fatigue, memory loss, leg cramps and still very sensitive to cold). Now, I feel less fatigued with the next jump up, although I still have several bouts of sudden fatigue, my excellent memory has gone to seed, extremely sensitive to cold, mild leg cramps, itchiness are still there. I miss my memory. Since I am still experiencing sensitivity to cold, I suspect that I haven't finished having my dosage upped. My concern is that my memory will continue to decline as the other symptoms improve. F 41 4 weeks
2/1/2010
 2  tot. thyroidectomy/papillary cancer major fatigue, irritable, loss of appetite, loss of taste, and nose bleeds. Had my surgery on November 12th and the radioactive iodine on December 3rd. I understand that it should take awhile for this medication to balance out, but I would think that I should feel some sort of difference. I am still sleeping about 12 to 14 hours a day. I wake at 6am, want to take a nap at 2pm and am back in bed at 6:30 or 7pm. Not sure if the nose bleeds are residual side effects from the radioactive iodine, can't find any infomation about that. F 38 20 days
150mcg 1X day
1/1/2011
Email
 2  hasimotos extreme fatigue, dizziness,chest pain, palps, jaw pain, left arm pain, headache, nauseausness (sp), mood change, anxiety, panic attack increase...going to dr this week for blood work to see where levels are..I know it is not heart, just went to cardiologist..feel so bad:( ...have been sick for 3 years, finally got an answer and fear worse then ever F 34 3 weeks
100 1X day
11/29/2010
 2   brain fog, some weight gain, fatigue, ringing in ears, hair doesn't grow no matter what I do, dizziness (not sure if it's related to the ear, fertility issues?? (tried for 2 years and nothing) I've been on Synthroid for so many years and used to be skinny as a rail. Fast forwards 9 years...weight gain of about 10 pounds without changing diet (I really watch what I eat). I have this annoying ticking in my right ear...and am tired every single day (I've caught myself falling asleep at work). My numbers are all normal but feel like I felt much better not being on this drug. Has anyone switched medication and noticed an improvement? Or does anyone think that they reformulated Synthroid and some people are having adverse effects? F 33 9 years
75 1X day
11/24/2010
 2  Tot.Thyoidectomy-Hashi's-ThyCancer Hair loss-Brittle Nails-Muscle Cramps- Brain Fog-Irregular Heartbeat- Anxiety -exercise and general fatigue started off at 50MG after hemi-thryoid, then 150MG after total plus calcium, vitamin E, Postassium,magnesium. Never had pain that woke me up in the middle of the night until the current dosage. Brain Fog/Forgetfulness is making life/work HARD. Plan to give it 6 months post-surgery then find another endo or naturopathic Dr if symptoms don't improve. Also weight gain on less calories. I even measure my food intake so the Dr can't claim I am eating more. F 58 2 years
150MG 1X day
11/20/2010
 2  Hypo Major weight gain, brittle hair and nails. Always hungry. Ok I am really tired of being told it is in my head. My family Dr. put me on it in 2009 and said the levels were a bit low. ever since I have gained almost 30 pounds and nothing I have tried to do has helped. Called her a few months ago and told her my concerns and she told me to go on Weight Watchers. I also tried to get off of it and I got flu like symptoms (which I was told I was wrong about hat also). Finally went to an Internal Dr. yesterday and he said there was nothing wrong with me and said to go on a 1400 cal diet and work out 5 days a week. I asked him if I can get off the synthroid and he said yes and if I wanted they can check my levels in the future WTF? He is also the one that said it was in my head that I said I had side effects from trying to stop the synthroid. NOW I am confused. I have decided that I am just going to stop it and be sick, since I already feel like crap anyways. SO FRUSTRATED! Why won't anyone listen. F 36 1.5 years
.25 1X day
11/3/2010

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