ZONEGRAN Reviews (ZONISAMIDE)

Average Rating: 2.9 (90 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

ZONEGRAN  (ZONISAMIDE):  Zonisamide is used with other medications to prevent and control seizures (epilepsy). Zonisamide is a sulfonamide anticonvulsant and a carbonic anhydrase inhibitor. It is unknown how zonisamide works to prevent seizures.   FDA Approval Date: 2000-03-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on ZONEGRAN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR ZONEGRANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Bipolar II Extreme depression, nausea, loss of appetite, vivid, terrifying dreams, confusion, feeling of being very slowed down, felt like I was dying. Only took it for a week; the side effects were unbearable. F 37 1 weeks
4/20/2004
 1  Mania Depression, rash, sore throat, insomnia I believe more research should be done on this medication before being prescribed for mood disorders. F 52 6 weeks
8/12/2004
 1  migraines ~!~!~!~!~ANXIETY~!~!~!~!~!~irritability would be putting it mildly! I snapped at my daughter for calling my son a nickname I have called him in the past (so the name SHOULDN'T have bothered me, and in retrospect DIDN'T). I was so stressed about everything, and while I live a VERY stressful life as a single mom and fulltime student, things were exagerated, and I couldn't eat, or sleep and I was visibly shaking from the stress!!! AHHHH! I understand my symptoms are rare, I decided to switch taking the pills from at night to the morning (because originally I had heard they would make me sleepy so I took them at night, when I couldn't sleep I wanted to try to take them in the morning, because it was out of routine I FORGOT to take them that morning... and by that afternoon ALL that stress started to MELT away and I could feel my body untense, and my whole body hurt... because for the past month and some my entire body had been TENSED UP, and then and there I decided I WOULD NOT take those pills EVER AGAIN!!! As far as the headaches/migraines go... it worked... but it was NOT WORTH IT to feel like THAT! If no migraines makes me a horribly irritable stressed out freak attack, then I'd rather have the migraines thank you (and anyone who's ever had migraines knows that's pretty durn bad to say that)! F 29 3 months
3/3/2009
 1  Headache prevention Severe anxiety which led to rapid heartrate and high blood pressure. Was taking 100 mg/night, and the two days I tried 200 mg/night led to obsessive anxiety bordering on paranoia. Even 100 mg proved to be too much and I had to stop taking it. It also caused some mental "dopiness", i.e. I couldn't think what I was doing or trying to say. (A lot of "um, um" moments.) Unfortunately, it also did nothing for preventing my headaches. Even if it had, though, I could not have continued taking it. I was well on my way to a heart attack, stroke, or possibly even a nervous breakdown. F 38 2 weeks
10/23/2009
 1  Epilepsy Weight loss, irritability, expressive aphasia, inability to focus or comprehend what others are saying at times, Sleepiness, Loss of appetite, depression I felt like I was going to just wither away and die if I continued taking this medicine. There was no hope if I continued it...it wasn't helping with my seizures regardless...I have absolutely nothing positive to say about this drug! It did nothing but make me look like a skeleton. F 29 7 weeks
400 mg 1X day
8/30/2014
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 1  Migraines Weight loss, complete loss of appetite. Eating made me physically ill. Lack of food increased my migraines. Nightmares, anxiety, irritability, no energy, depression. F 35 2 months
300 mg
7/15/2015
 1  Epilepsy Slower mental processing; inability to find specific words in context, couldn't keep up in a long conversation with one person, forget my train of thought, reading became harder, an overall understanding what was going on or explain anything was hard. It helped stop my partial complex seizures but at the cost of slower mental processing. I will be going back to Lamictal. the switch occurred because we did not know that the other medicine I was on was a seizure stimulant so now hopefully I will be right back to where I was before zonegran came into my life and disrupted things. VERY dissatisfied. F 21 1 years
200 2X day
9/7/2015
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 1  seizures Memory loss Stuttering incapable of speech dizziness angry depressed crying stomach aches diarrhea unable to eat no ambition to do anything this is a medication from hell I felt this way 24 hours a day for over2 years and was still having seizures all the doctors did was increase it milligram by milligram now I'm going through the side effects of coming off of it the same thing all over again if they offer you this run like hell find a new doctor they probably own a stock to all of you coming off of it I wish you well God bless The horrible medication they should take off the market it is almost like an illegal drug that drag you into it put you through hell to go on it and off of it this is the horriblest thing I've ever been on to everyone on it good luck I wish you well god bless you all F 1 days
600
3/2/2016
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 1  seizures Can't taste food it all tastes the same will it come back after time??? ;( feeling emotional but still early days may not be the Zonegran for emotions don't know! F 45 2 months
200mg
4/16/2016
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 1  Chronic back pain Severe Anxiety, Depression(not normally depressed) Suicidal, Panic Attacks(never had before). Muscle tightness I'd be really careful starting this medication. It made me into someone I wasn't normally and almost committed suicide. Anxiety/Panic went away almost immediately when I stopped taking zonegran. My whole body relaxed when I stopped taking the medication. I tried this medication for chronic back pain from lumbar back fusion and cervical neck degenerative disk disease. F 42 3 months
100mg
5/19/2016
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