ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  To stop smoking In the middle of week 3 started getting HIVES and literally havent stopped, - just in severity from really itchy head to one or two on my body, to all day long, going beserk at night, covering myself with calamine lotion which helps. Feel like ripping my skin off Not sure if I should stop taking them. Gave up smoking on 4th day of week 2 and dont feel like one at all. This has worked for me although cant handle the hives. F 40 28 days
150mg 2X day
3/24/2011
 5  stop smoking/mild depression ears ringing is my biggest complaint. absentminded. trouble sleeping. the first week taking zyban, i felt very jittery. that has subsided. the ringing of my ears is so loud that i have to fall asleep to the tv loud to drown it out. i wake up often (every 2 hours and up for 30 mins-an hour at a time). the first time i wake up, i feel like i've gotten a good nights sleep, but have only slept 2 hours. it's then hard to fall back asleep because i'm not tired. this goes on until i finally give up at 5:30am. this happens every night. HOWEVER, i otherwise feel wonderful!! i've been a half a pack a day smoker for 20 years. i'm now down to 3. no desire to smoke, and when i do, it's not fulfilling at all. i can only get through half a cigarette and realize that it was a stupid choice and it didn't do anything for me anyway...when i tried to quit smoking before, caving in and having a cigarette felt wonderful! now, it's not enjoyable. my mood has also improved. i've taken anti depressants before and know that sometimes my mood can get worse before it gets better when taking them. this did not happen with me on zyban. i'm quite content and optimistic. i think that there are far more good experiences with zyban than bad. it wouldn't be on the market if it the majority had the issues that i'm seeing on here. i have some side effects that i'm not fond of. but it's temporary, and if the end result that i'm no longer smoking, then i'll be happy to have ringing ears and sleepless nights for a few more weeks. F 34 23 days
150mg 2X day
10/19/2011
Email
 5  Smoking cessation Slight nausea the first two days, deceased appetite. That is it. Yesterday (day 4) I noticed that I was no longer feeling pleasure from smoking. Went to a bonfire and everyone around me was drinking and smoking, and I had one cigarette the whole 5 hours, and that was just out of habit. Normally I would have probably had 8-10 standing outside like that. I do not crave AT ALL. I am very pleased! As you can tell, I have been in good mood, no mood swings, no bad thoughts. I know this drug isn't for everyone, but it's definitely for me. F 27 5 days
150 mg x 2
9/14/2013
 5  stop smoking Phew...angry, pissed off, paronoid. Frustrated, argumentive, depressed, anxiety, yet better than last time I went on them in 2001, I got hives only about 5 hrs sleep a night, extreme aggitation..I have stop smoking yet alcohol is still a trigger.… F 43 7 weeks
11/28/2011
 5  stop smoking I have been a smoker for 40 years. Struggling to quit for 20 years. I took Zyban 6 years ago and after 3 days had lost interest in smoking. Never smoked since. Cannot remember side effects they cannot have been that serious HOWEVER, I had a serious episode on the last day of the treatment. I became enraged at a neighbour who had been giving me a hard time for 5 years and I went in his garden and destroyed it, like the Incredible Hulk. Next thing I know, I wake up in bed with total memory loss of the last 20 minutes. I have a question. SInce I quit smoking with Zyban, (6 years) I have been a different person. No enthusiasm for life , no interest in doing anything. I used to be very active, I now spend my time reading and playing with computer. Not depressed, just going through the motions, without any real motivation. Is it possible that ZYban has permanently affected my brain? affecting the reward centres ? Anyone with the same experience, months after quitting with Zyban ? ALso a message to all of you who feel depressed. I have stopped smoking many times, cold turkey or with patches and everytime I would feel very angry. Within days I would hate my life and everyone in it and feel suicidal. It is the nicotine withdrawal. No Zyban. Talk to your GP. Get antidepression pills. Nicotine addiction is very serious and there are a lot of withdrawal side effects -physical and emotional. You are not being a sissy by getting help. F 63 60 days
1X day
12/24/2011
Email
 5  Stop smoking I had insomnia and after 5 weeks very emotional F 31 4 months
150mg
1/31/2012
 5  Quit Smoking Day 1 Felt I had energy Day 2 good to go. Day 3 up'd the dose and Whoa. By day 10 I was having crying fits then day 12 I was zombified. Constipation, butterfly rash, hot flashes, insomnia, loss of appetite. agressiveness and rage. I came online to see these were some side effects. But I was so ready to quit smoking I made myself stick to it. I quit on Day 16. And am 4 days into no cigarettes or nicotine. I am happy, but I am having severe insomnia. Which is not good. I have a regular sleep pattern and I absolutely need 8 hours sleep. I've been getting like 3 hours a night and the rest of the night I try and try to go back to sleep. I think I'll hang on for another week or two. But I think I will go off the Zyban. But it is amazing how I do not even crave a smoke even being around it at the bar. Also having some lapse in memory. Sometimes confuzzled. F 45 20 days
150 1X day
3/29/2012
Email
 5  Smoking cessation disturbed sleep, vivid dreams and occassional nightmares, blurred vision and dizziness at times, hot flashes, quick to anger, lack of emotion and listless feeling at times Although this drug has side effects, they were tolerable overall. I would not have been able to quit smoking without it!! I have tried several times and always broke down with severe cravings. Once I started taking zyban, I had no cravings and wasnt aggitated like before. When I did smoke, didnt really have the same effect so stopped wanting them after the actual habitual part wore off. I experienced some nicotine withdrawl symptons at first but knew what they were and not side effects of zyban. The worst part for me was not getting good sleep at night. I need a full 8 hours and was unable to get this. I had no problem falling asleep but unable to stay asleep for 2-3 hours out of the night no matter how hard I tried! Stopping after 2 months of therapy....had my first cigarette last week and couldnt stand the taste of it and had absolutely no effect on me. Ready to go it on my own and get some good REM sleep back. F 38 2 months
300mg 1X day
4/5/2012
Email
 5  Quit smoking Zyban is great..took it first day and immediatly i wasnt craving cigs..some side effects where gas insomia and the feeling of being high(which was great for me lol ) the off the wall side effects people say didnt happen to me..i exercise drank plenty of water and just keep busy...i guess its different for people F 21 7 days
5/4/2012
 5  Quit smoking felt really sleepy the first week as the drug worked it's way into my system and felt quite disconnected, that's the best way to describe it, I waited for 7 days before upping the dosage to twice daily, for 2 nights I barely slept and felt sick but that passed and those are the only side effects I had i smoked like crazy for the first 9 days on Zyban and panicked that it wasn't working, woke up on day 10 and haven't touched a cig since then, haven't had any cravings or withdrawal symptoms or side effects, I have about 2 weeks left to go but regularly forget to take the meds so cant see much of a problem coming off them but I will finish the course. All in it's worked for me so I think it's great, my GP was brilliant he was very up front about possible side effects, if there were any mental illness or depression issues etc, good luck to anyone who gives it a go, hope it works as well for you as it did for me :) F 40 7 weeks
300mg 2X day
7/15/2012
Email
 5  Depression lost 5 pounds so far. Not interested in food or wine (unusual for me LOL) day 4 a little light headed - felt high. Kinda nice. Not sleepy all the time like I was on citopam. Lots of energy. Feel Happy. I have tried Prozax, zoloft, effexor, celexa, couldn't stand the side effects. Zyban is a different animal...really working for me...AND I've lost a little weight! a nice bonus to having life and personality back. Works for me. F 49 2 weeks
150 mg 2X day
8/17/2012
 5  To Assist with Nicotine Addiction Vivid dreams, dry mouth, insomnia, loss of appetite I had a smoking quit date of 3 weeks after starting meds, but quit after a week and have not had any cravings for nicotine. Reading everyone's comments, this medication is obviously not for everyone. I would suggest that if you are trying to quit nicotine, try Zyban for a day or two. If you are getting side effects that are unbearable to you, then stop taking it. For me, I can handle the side effects. It is worth having the side effects than to go back to smoking. F 43 20 days
150 MG 2X day
4/30/2013
Email
 5  To Stop Smoking I have been taking zyban for the last 3 weeks stopped smoking on day 8 was very impressed that my cravings were not too bad. Sleeping was a nightmare woke up every morning at 3am wide awake took hours to get back to sleep, i got very nervous if i was going anywhere like to get my hair done or someone else was driving and im not normally like that if i had not of been taking the medication i would of been worried about myself !! Then on the 10th day of not smoking i had an itcy arm in the morning then by 5pm i was covered in an itchy sore rash from head to toe i have not normally got sensitive skin. I rang the doctor he told me to stop taking the medication immediatly. So today is my first day without zyban just patches but feel confident enough that i am over the worst part hopefully, i hope so much that i can do it i feel so much healthier and the smell of other people smoking really annoys me. Not sure if the doc will let me take them again but fingers crossed i stay smoke free. F 24 3 weeks
2/2/2006
 5  stop smoking 3rd statement so far,can be found a few below.If you read my comments etc then feel free to email me if you want to pass on any comments to me.Or even if you just want to winge to a stranger..be my guest... I am the 4th comment below this one.Just an up date really.Oh before i start i'd like to give a message on to 'MR..EVRYONE MISSUES ZYBAN',fact of the matter is your wrong luv!!Used it as directed,was a good girl but still had horrific side effects.Anyway,as i was saying.I'd like to say that i have stopped taking the drug now because i can no longer suffer the dizzyness,sickness and tiredness.All this was getting too,too much.Did'nt do it on doc's advice but when i told them on my next visit they said that was fine,basicly.I feel so much better,no side effects any more for smoking or zyban,and thought (to be honest0 that i would have some kind of dependancy on this drug,but not at all.I'm so pleased to be off it,i feel so much happier now!Chin up,good luck to all F 27
3/17/2006
 5  to stop smoking Most annoying side effect is my mouth feels constantly strange. This happened 24 hours after taking dug, on day 12 now have bowel problems, stomach upset, anxiety, muscle soreness nothing Major but I dont plan to be on this drug any longer than I need to. This is a remarkable drug with exceptional power I feel uneasy about being involved with. I physically could not continue smoking up to my quit date I had to stop sooner and I didn't want to as I felt i would fail if I was stressed before my quit date. (You know when you normally cut down and are a basket case before you even give up)But I have stopped with next to no problems, It isn't easy but it isn't completely horrific like cold turkey. I know I have stopped smoking now forever and that has never been the case on other occasions when I have tried to quit. Not happy about the drug but the ends justify the means! F 30 2 weeks
3/6/2006
 5  To stop smoking Insomnia Why are you guys in the U.S being made to stay on the drug for so long they are just trying to make more money out of you..Here in the UK its free and you only have to take it for 6 weeks and then you come of it, i think it would course alot less side effects if you didnt stay on it for so long F 24 5 days
6/26/2006
 5  to stop smoking i had a few side effects but not any major problems. Headache, insomnia and dizziness when i stood up. I was also a bit angry but that was probably nicotene withdrawl. The first three days on zyban were the worst. The first two days i felt really pissed off and bitchy and then the third day i felt really high and then the rest of the time i was on it, i felt normal. Wasnt tripping out or anything. It made me feel like i wanted something but i didnt know what it was. I think it was my body wanting the nicotene but my mind was like no i dont feel like that. Sounds weird but it worked! I really think it depends on the person with all these side effects. You just don't know until you try. Would you rather the chance of some side effects or die of cancer? I have quit now, and i used to smoke a pack a day and I thought nothing would help me stop. F 22 2 weeks
1/19/2006
 5  Stop smoking Dry mouth. Maybe a tiny bit lightheaded at times I was a 20+ a day smoker who thought I would never quit. I dont know how these tablets work, and I appreciate from reading other comments on this site that they are not for everyone, but they have worked a treat for me as I am now a non smoker and I really feel like that will be forever. F 35 10 days
1/28/2008
 5  Bipolar Depression None F 19 7 months
2/29/2008
Email
 5  Quit smoking A little insomnia, feeling a little slow in my thoughts- or a little disoriented. Wow, this has made quitting sooooo easy! I would recommend that you at least TRY it before you get scared by other people's comments. It has really worked for me. F 29 11 days
9/30/2007

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