ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  nicotine addiction First few days were interesting with bouts of mumbling speech and my eyes felt as though they were crossed. When the dosage increase happened is when things really got fun, couldn't sleep or maybe I did just not sure. The third through the eighth day of the increased dosage I was high as hell. Finished up a lot of projects that needed finishing. The wierd part was that during the first few days i chewed and smoked like a mad man and when I woke up on the fourth day not even a thought about nicotine. Dont want any and cant stand the smell of cigarettes or chew. Since day nine its been smooth sailing and I have no major concerns about my mental or physical health. Absolutely necessary to stay hydrated while using Zyban. I am drinking about a gallon and a half of water (beyond other fluids) a day which is about a half gallon more then usual. May seem like a lot but my job requires a lot of physical activity so hydration is key. Nutrition is also important I will force myself to eat regarless of how hungry I may be. Without regular food intake I'm sure the side effects would be worse. When I say nutrition Im talking about real food not processed food or anything from a fast food joint or restaurant. Your only going to feel as good as the substances that your ingesting. So minus the pills eat good and stay hydrated!!!!!!! Good luck and know your limitations if its to much for you stop using this drug. Use your common sense simple as that. M 29 19 days
150MG 2X day
9/7/2012
Email
 5  smoking cessation Jittery but tolerable, lots of energy, good focus, occasional memory loss, but after day 7 I quit smoking and that's when I started waking up every at night. Called the doc for something to help me sleep since I'll be on this for at least 12 weeks. I have really positive things to say about it but the sleeping issues after I stopped smoking are pretty rough. I smoked for 15 years and quit after 7 days of taking Zyban. Days 1-3 were 1 pill 150mg then day 3, 2 times a day. M 33 9 days
150mg 2X day
5/10/2012
 5  Quit smoking Dry mouth, heightend sex drive, slightly "trippy", blured vision if looking at a computer screen too much - but I think that may have to do with withdrawl I started with one 150mg a day for 7 days while still smoking and was wondering what effect this drug was supposed to be having as I didn't feel any different whatsoever and was still smoking a pack of 25 a day. When I stepped up to two a day per instructions I immediately noticed that I wasn't particularly interested in smoking. When I did, it had no real effect and actually gave me a slight nausia. Having tried NRT products which just change the delivery mode for nicotine, Zyban has really worked for me. I have absolutely no desire to smoke, and on the odd occasion when I have been offered one socially, it did absolutely nothing for me, apart from make me feel slightly ill. M 42 30 days
150mg 2X day
2/7/2011
 5  To quit smoking Initially the dose was 1 x 150mg for 3 days then 1 twice a day 8 hours apart... In the first few days I felt weird. The third day, I was down, depressed about the smallest things. However, yesterday and today the 6th and 7th day I feel great. I stopped smoking yesterday (6th day) and after smoking for 20 years, this is the best thing!!! DON'T DRINK WITH ZYBAN!!! M 35 7 days
150mg 2X day
9/20/2010
 5  Smoking cessation No side effects that I was able to ascertain, aside from maybe not falling asleep as quickly after being woken in the middle of the night. I was astonished at how effective this drug was (or perhaps it was placebo effect?), as it takes a week for it to reach saturation level in the body, and yet within 8 hours of the first dose I was not feeling withdrawal. It has been over a week thus far and still feel the same...uninterested. After 20 years of one pack/day. No other behavioral changes (aside from perhaps not being as quick to be annoyed by life!) can be noted. I will continue for the full three months just in case, but this is a more sensible option for quitting, since it doesn't involve continuing to put nicotine into your alreadt addicted system. That, and since it's now generic, much more afforable under insurance. M 38 3 months
150 2X day
11/5/2010
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 5  Quit Smoking since the first day, i have had a lot of energy. im not as impulsive and i notice myself paying attention more frequently. smoking isnt as pleasurable and im simply feeling as though im just going through the physiological routine of it now, rather than getting any satisfaction from it. i had a few glasses of wine a few days ago and noticed my tolerance had decreased. i am at times feeling irritable but for the most part these brief phases throughout the day pass. also, like clockwork, in the evening i am getting headaches that end just as quick as they begin. im also feeling an increase in my libido. at first, i was a little more spacy at times but this seems to be passing as well. i dont know why other comments on this thread are so negative: so far, and its only been a week, i love this drug! i have so much energy and i dont sit around fretting about stuff throughout my day: i just get it done. i can focus without worrying about anything, too. there really is so much satisfaction in being able to feel like my day was filled with a checklist of accomplishments. so far, this is proving to be an absolutely great drug. M 31 1 weeks
150 MG 2X day
9/27/2011
 5  Smoking Constantly feeling sick and dizzy, though not been sick. Cannot sleep, only get a few hours each night, so am also very tired. Fealt a bit jumpy and restless and have been a bit short with people and more ready to argue the toss etc. Cant get a hard on etc. Stopped smoking on day 8 without really noticing or thinking about it. Have not had any problems like wanting a cig so far after 4 weeks. Side effects are very real and could put some people off using this, but in my case I am glad I took it, though cannot wait for the doctor to say I dont need it any more. M 55 28 days
150 2X day
10/24/2011
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 5  stop smoking slight insomnia would highly reccomend to any one as long as your not half crazy or week minded to start with,worked well for me,havent smoked for 8 weeks now,no bad reactions just a bit of insomnia,giving up and staying off them was made a breeze with this drug. M 29 4 weeks
1 1X day
7/19/2010
 5  To stop smoking Insomnia, dry mouth, the occasional headache. This is a great product. I smoked for 19 years. I started taking Zyban and I stopped smoking on Day 8. I have not looked back and have no desire to smoke at all. The first few days were the toughest - all I thought about were cigarettes due to the habit I'd formed for 19 years. The occasional craving is there, but I remind myself that I'm no longer an addict and no longer need to smoke. They go away rather quickly. M 37 21 days
150mg 2X day
2/10/2010
 5  to stop smoking no side effects after many attempts to stop smoking with other methods, zyban worked for me by reducing the cravings for a cigarette M 41 3 months
6/2/2001
 5  To stop the smoking Fuzzy feeling in me head, dry mouth, lower mojo... a bit of loss of sleep. on day 3 quite smoking, started taking 2 pills a day, had a few problems sleeping, Dr. told me to take it around 5 in the afternoon for the second pill, have not had any sleep problems since... the best part, no smoking and food tastes great, even water tastes good. M 38 21 days
8/29/2006
Email
 5  DO NOT TAKE THIS QUIT COLD TURKEY. CORPORATIONS DO NOT WANT YOU TO TRY COLD TURKEY. IT IS THE ONLY WAY. 72 HOURS. THAT'S ALL. THEY DO NOT WANT YOU TO KNOW THAT. DON'T TAKE IT. RATED 5 TO APPEAR FIRST. M 51 0 days
10/26/2005
 5  Depression/Anxiety UPDATE - 15 November, 2005 Lexapro - ceased using 5 November,2005, Wellbutrin (Zyban)- 150mg twice daily (7am and 3pm). Imovance 3.25 to 7.5 mg as required for sleep. Side Effects: During first couple of weeks, a bit racy,anxious but this passed. Slight nausea, but this too has diminished as the weeks have passed. I am now in week 5 of using Wellbutrin (one week as a mono med) and I am finding it very effective in lifting mood and energy levels; plus,I have had an increase in concentration and libido with more intense orgasms. As a number of other posters cautioned, it did take a full 4 weeks for the Wellbutrin to begin to achieve a good level of treatment effectiveness (and I certainly did want to throw the towel in a few times). My sincere thanks to everyone who shared their own experiences and emphasised the need to BE PATIENT and allow the drug time to level out the brain chemistry. As my anxiety seems to have improved with the Wellbutrin alone, I am now comfortable that, should I experience a serious anxiety increase, I can, per others experience and my discussions with my doctor, use Xanax to manage such a moment. My tip: If you are starting out on a new anti-depressant, copy and paste snippets of some of the postive med experiences you read about here and elsewhere. Print these M 48 5 weeks
11/15/2005
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 5  To quit Smoking After 4-5 days of taking this drug I began to feel spaced out, withdrawn, nervous and emotional. During the period between day 4 and day 7, I basically felt as though my brain was being twisted inside my skull - almost like a chemical labotomy! Due to not feeling present in the here and now, my ability to do the most basic things were affected - even a simple crossword or helping my daughter with her year 5 math homework became stretching to me - if you take it be prepared for Zombification! After experiencing the Zyban experience, I'm convinced that it works by making you feel so withdrawn, screwed up and ill, that you don't notice anything as little as nicotine withdrawal! By the way, I quit without aide - it just took a little of positive thinking....I scored this a 5 so that it appeared high on the review list. M 37 7 days
11/3/2005
 5  Zyban Worked great with helping the urge to smoke. Although, my right eyelid started twitching the entire time I was on it, and didn't stop until the the meds stopped. I lost a lot of sleep, but I got through it all ok. M 21 3 months
3/22/2006
 5  anti smoking insomnia,skin rash, anxiety. As much as I am very impressed with this drug -it really does help greatly against craving- I strongly feel that its side effects are quite vicious and would advice anybody to STOP TAKING IT as soon as you feel confident being able to do without. I have taken it for exactly 3 weeks,at the end of which I suffered pretty irritating skin rash, insomnia with an average 3 hrs sleep in 10 days, and occasional but intense anxiety attacks. Don't let yourself be fooled thinking these are withdrawal pangs.The physical effects of stopping are minimal and these side effects are 100 % drug related, although not everybody is equally sensitive. Meanwhile, one week after quitting on the drug I am doing very fine without it and not smoking almost as easily ! You can do it too ! M 47 3 weeks
9/19/2006
Email
 5  Smoking Tight neck & back muscles from day 5-10. Problems falling asleep initially, but has slightly decreased - meanwhile, feeling very alert (never sleepy during the day). Horrible itchy bumps (so bad that I think these may be hives from something other than Zyban). Upper stomach pain which has increased with time. Slight mood swings, but manageable. Rare but painful urethra sensation, though not during orgasms (which, BTW, are a bit more intense). If you are sick of being powerless over nicotine you must try this. This has been my second time taking Zyban to cut the habit. Last time was very successful, but several emotional issues (relationship, business & Sept. 11) came to a head right after I was weened off the drug. Still, I have been using in conjunction with "the patch" (which I have quickly decreased in dosage to 7mg/day) and have almost NO desire to smoke! When I do, the urge passes within 3 minutes (easy to take my mind of of it too). In the short term this drug does cause me some pain, but it is well worth one month of discomfort to save 10 years of my life. M 31 18 days
9/16/2005
 5  to stop smoking Minimal side effects, slight chest tightness for 3-10 seconds every few days but nothing that caused me to worry. No problems sleeping at all. Never had an overly dry mouth (try a glass of water if you do ), no rashes or hives. I didn't have one dark or paranoid thought - I must be a stable kind of bloke. And keep in mind SMOKING DESTROYS YOUR LUNGS!! I would recommend these to ANYONE. Nearly a year now without a ciggy I can breath easily, take part in sports 2-3 times a week, and don't cough up my lungs every morning. Get some of these tablets, feel healty and enjoy your life. M 27 14 days
11/7/2006
 5  to quit smoking mild insomnia, rage attacks, loss of libido. the most successful i've ever had. 100% success rate. neeeds longer than 3 months though. with excercise and diet there is nothing better. M 29 90 days
4/4/2006
 5  Quit Smoking Sore neck, headaches, mild shakes, brief depression I quit smoking on day 8, today is day 14 and I think im going to quit Zyban before syptoms get any worse, not saying they will do but I dont wont to risk it. Good luck to everyone attempting to quit.....read Allen Carr's book, alot less side effects :) M 31 14 days
4/12/2006

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