ZYBAN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (580 Ratings)

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 ANTIDEPRESSANTS SMOKING CESSATION AIDS UNCLASSIFIED

 Type: Brand name discontinued; available as generic

  

ZYBAN  (BUPROPION HYDROCHLORIDE):  This medication is used in combination with a stop-smoking program (e.g., support group, counseling) to help you quit smoking. Bupropion can decrease your nicotine withdrawal symptoms (e.g., irritability, anxiety, restlessness) and your urge to smoke. Quitting smoking decreases your risk of heart and lung disease, as well as cancer. This medication belongs to a class of medications known as antidepressants. It is not known exactly how bupropion works to reduce smoking urges. It may work by restoring the balance of certain natural chemicals (neurotransmitters) in the brain. Discuss the risks and benefits of this medication, as well as other ways to quit smoking (such as nicotine replacement treatment), with your doctor.   FDA Approval Date: 1997-05-14 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29


RATING  REASONSIDE EFFECTS FOR ZYBANCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Stop Smoking Very Dizzy I feel horrible after taking zyban. I get very dizzy with just one pill and i can't even take another pill during the day. Two pills a day..BAD THING I am not functional. My last pill was 10am yesterday morning and it is now noon the next day and I am still feeling the effects of the drug. I am very dizzy. F 40 5 days
3/18/2008
 3  to stop smoking nausea, insomnia, headache, ringing in the ears, hallucinations (to touch), lack of concentration doubling the dose of the zyban was the beginning of the end for me...after almost a week of severe nausea, insomnia,persistent headache and a few hallucinations (always after id taken the 2nd dose)...i went to the dr and he told me it was too much for my small frame (i weigh under 50kg)...and to take a day off and keep on half the dose from then onwards...1st day on half dose (1 tablet) and much improved...still not smoking and not craving it either:)the hallucinations scared me a lot tho...im thinking of only taking zyban for another couple of wks and then ceasing it...anyone else hallucinated but was aware they were at the time? i didn't notice too many ppl mentioning this in this forum. F 28 12 days
3/30/2008
 3  stop smoking severe diareha and vomiting. dizziness, light headed,sweats All was fine till the 4th day when I started 300mg. An hour after second dose I had ringing in the ears and stomach pain. Within two hours I was throwing up. I threw up every hour for 12 hours the every 3-4 hours. Diareha started somewhere in the 12 hours I was vomiting. Have not thrown up in 12 hours now. Still have bad diareha, Have not smoked in almost two days. Have stopped taking zyban for now. I will be cutting dose down to 150mg as soon as I am feeling better. F 38 5 days
1/14/2009
 3  Quit Smoking overwhelming feelings of despair, depressed mood, severe agitation, insomnia, paranoia, anxiety, irrational and scattered thought patterns, twitching limbs I am one of life's happy people - so having overwhelming feelings of despair and feeling depressed has been extremely confronting. This is my third or fourth attempt using Zyban. Only side effects I had during previous attempts were twitching limbs and a general feeling of well being. As I had taken Zyban numerous times before, I forgot to do slow build of 1 per day for 3 days, then 2 per day thereafter - especially as I was keen to quit. I just kicked off with 2 per day from day one. I think this may have contributed to the pronounced difference in my experience of the side effects. I have not smoked for 5 days (I am a pack a day committed smoker - it has been over ten years since I have not smoked this long. Even with patches on I would chain smoke). I have now reduced dose to 1 per day. If side effects have not diminished by next week, I will stop taking Zyban. I would rather stick with not smoking than endure these negative feelings again. It has given me a valuable insight into de F 40 11 days
1/21/2009
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 3  to quit smoking Nausea and headaches at first, than normal, now on my 4th week I have had trouble sleeping, getting hives, and easily irritated In the begining I was very satisfied. It worked, I quit, but now after 4 weeks I am getting weird side effects. Or at least I think it's from the zyban??? Anyone else start getting hives or weird rashes after some time on the meds??? All I can say is I plan on stopping the zyban and staying smoke free. I believe this medicine helps, but it does have alot of side effects that most people probably wouldn't want to risk. F 26 4 weeks
3/25/2009
 3  to quit smoking Agitated, can't sleep yawning alot moody Have only 3cigg since my quit date September 15,15 F 58 1 months
10/17/2015
 3  To stop smoking Dizzy surreal shaky blurred existence. Couldn't drive anymore, couldn't sleep. Felt mentally vacant, docile, slurred speech. Had to have ambulance for suspected stroke ECG and MRI scan and hours in hospital. Not a stroke just physically shaken drained and a complete mess. Felt on the verge of seizure constantly. Was a struggle to hold on to consciousness and reality. Works for stopping smoking but the side effects are immensely dangerous to the very life you're trying to save from smoke. Just seems a guarantee of a quicker death. Was advised by every doctor I saw in the past 5 days (because of the side effects) to stop taking. Started smoking again immediately. F 49 14 days
150
5/27/2020
 3  Depression No side effects at all Came to find out about Bupropion (Wellbutrin/zyban) myself while scrolling through the internet for an antidepressant that did not cause weight gain. I started on Sertraline in 2019 and it was fantastic, turned my life around within a week. Slowly increased the dose over 3 years until I was on 150mg, the low sex drive and weight gain of 18lbs was really getting me down. I asked the GP about bupropion he said it was only prescribed here in the UK off label but he was happy to let me give it a go. No side effects at all while coming off Sertraline and starting Zyban so much so I felt as though it was not working, 4 months in I am now taking 150mg twice a day, I still just do not feel like it is cutting the mustard, GP said I can increase to 3 times a day but I'm just not sure, I have lost no weight at all which was the main reason I started this pill, was hoping for a miracle I supposeā€¦ F 32 4 months
150mg 2X day
7/31/2022
 3  stop smoking I am on day 9 of my course now and stopped smoking on Monday. I cant say I havent had any cravings but they have been managable. I have read a lot of the feedback and do think that possibly Zyban is taking the blame for normal nicotine withdrawel symptons - but we shall see. Zyban is supposed to minimise weight gain when stopping. Does anyone know if it all piles on when you stop the tablets? F 49 10 days
4/8/2009
 3  depression In the very beginning, nausea-- intense brief waves of nausea. The nausea went away after the first few weeks. Overall side effects include mproved sleep, constipation, feeling a bit jittery, stressed, slight weight gain (few lbs). Since starting this drug I've also been experiencing a lot of yeast infections, which is NOT normal for me (approx. in 5 months). I tried several OTC treatments, pill from my physician but they keep coming back. I am wondering if it is related to the drug...but I haven't seen anything in the literature. I am planning to go off the drug to see if it helps. F 32 5 months
6/3/2008
 3  stop smoking after 2 weeks started itching back of my neck and head.itchy palms,benydryl helps. wake up every night a 4 am. force myself to eat. lost 10 pounds in 2 weeks. bad dreams, might be the nicotine patch.time goes by fast.quit smoking after 2 weeks of taking it. never want to smoke again! F 41 2 days
2/2/2007
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 3  quit fags first day, light headed and vague. second day slight red rashy thing on my stomach which i kept a close eye on, but since gone. now sixth day and maybe getting slight metallic taste in my mouth (bit like when pregnant) which i hope will aid in detering me off the fags, cos other than that, i feel the same and am smoking the same... posted something first day and couldnt find it! shame, i was hoping to record my whole Zyban experience on this site with all you other quitters.. badly side effected or not. I was really scared after reading everyones reactions, but as still ok on 6th day, i am hopeful, positive and optimistic. I need a kick start, i really want to quit. Been smoking since i was around 6..yes your all thinking im full of it, but unfortunately its true.. so 28 years later.. apart from quitting for 3 years and then starting again 6 years ago, im pretty much a die hard smoker. i also drink a far bit on a daily basis (which according to the info isnt a good mix with Zyban). Find out tomorrow if the lump in my mums throat is benign or not... shes been smoking for as long as i have known her.. good luck to one and all in our united quest of freedom.. F 34 6 days
9/13/2006
 3  To stop smoking Slight headaches, waking up during the night and then stuggling to fall asleep again, joint pains (back, neck, sholders and knees)- so bad that the doctor had X-rays taken. Mood swings, irritability - wanting to cry easily I've stopped now for 14 days - I did not, as prescribed used Zyban for 10 days and then set a date - From day 1 that I started taking the pill, I've stopped smoking. These first two weeks were hell. Maybe because I didn't take the tablet as prescribed, I can't really say that it made things easier for me. F 35 14 days
7/24/2005
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 3  Depression I have noticed mild brief stomach pains and slight diarrhea. F 28 2 days
7/16/2005
 3  quit smoking Insomnia. Irritability. Depression. Inability to talk with others. Feeling F 32 2 weeks
9/1/2004
 3  quit smoking Insomnia. Irritability. Depression. Inability to talk with others. Feeling F 32 2 weeks
9/1/2004
 3  Quit Smoking It's only my 2nd day on this stuff and already I don't like it. I have been getting a loud ringing in my ears, headaches, I'm really tired and off in another world aswell as having the shakes. If my smoking doesn't decrease soon and I can't see any beneficial effects from this drug then I will stop taking it. So far not so good. F 28 2 days
4/8/2005
 3  Stop Smoking Hives, stomach aches, severe chest pains. This is the second time that I have been on Zyban, the first time I quit for almost a year (364 days), that was almost four years ago. Side effects are a little different this time. First time had bad stomach aches, panic attacks, rapid and irregular heartbeat. I have not smoked in almost two months. Upon my doctors recommendation I was going to take the meds for a year, unfortunately I have changed my mind. Within the last week I have experienced severe symptons which I thought were unrelated to the Zyban, I was wrong, the hives are driving me absolutely bonkers and the severe chest and arm pain scared the heck out of me, I thought that I was having a heart attack. Once I found this web page I realized that it was the meds. I'm done now, I'm not taking it any more. There are a couple of good things that came out of taking it, I'm sleeping better and I have an increased libido. I'm going to do my best to stick with quitting because I don't ever want to take Zyban ever again. F 37 9 weeks
5/7/2005
Email
 3  Stop Smoking Very itchy hives particularly on hands and feet - drive you crazy! Very bad problems with insomnia when never had any trouble sleeping before. Awake every hour during the night. Went back to my doctor who has advised me to stop taking zyban because of the hives, this is a bad side effect apparently. I am sorry to stop taking them as I have stopped smoking now for 4 days which is amazing for me. Very little cravings with zyban F 36 13 days
5/31/2005
 3  To Quit Smoking Dry mouth, agitation, crying, hysteria, reduced depression Zyban helped me to stop smoking and lessened depression. I haven't had a cigarette in 3+ months. But lately I'm much more agitated, cry easily, and work myself into hysteria when life stress feels overwhelming. I am tapering down and will stop taking the drug next week. F 54 3 months
4/16/2005

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