EFFEXOR XR Reviews (VENLAFAXINE HYDROCHLORIDE)

Average Rating: 3.0 (2225 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

EFFEXOR XR  (VENLAFAXINE HYDROCHLORIDE):  Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 1997-10-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on EFFEXOR XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR EFFEXOR XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Panic Attacks, Depression, GAD At first, insomnia, sweating and clammy palms and feet, lightheadedness, restlesness, slight nervousness. Increased dose from 75 mg/day to 150 mg/day, same side effects as before but they go away within a week This is really starting to help. I've only been on it for 3 weeks now, and the 75 mg/day was helping, but since i've gone up to 150 mg/day, man I'm feeling better. No more panic attacks, though I can sometimes feel as if my body is trying to have one, general anxiety is pretty much gone and I feel happier. No more social anxiety and I can actively participate in college classes again without having to hide in the corner. Only gets better from here! Thanks Effexor :) M 25 3 weeks
2/13/2005
 4  DEPRESSION SWEATING,OCCASTIONAL DIZZY SPELLS M 40 6 months
5/2/2002
 4  Depression Well, I have been on it for 3 months and I am very happy. I have no mood swings, I am able to laugh, cry, be sad, etd. at the proper times. I heve experinced some side effects. the speed feeling for a few weeks, bad orgasms ok now, sleepy, it is going away, missed a dose and had that weird head syndrome. I was a heavy beer drinker and now cant stand the taste of alcohol of any kind! I liked drinkng and the Effexor took that away.Saves me $$$. Kinda took to coffee real heavy though it has been tapering off. I may have weight gain as I quit the beer thing of at least 6 pK A and I have lost no weight. But I am happy. Oh yea, I am kinda having a hard time thinking of certain words at times. I have no advice. If it works, it works. The unfortunate thing about all drugs is that they are not natural. I fully expect to be on this till it stops workjing and ALL A.D.'s will stop working as soon as your brain can adjust to the chemicals.....As for withdrawls, heck, I cant stop COFFEE without a headache and feeling sleepy for 2 weeks. M 37 90 days
1/10/2005
 4  Depression & Anxiety (panic attacks It took 9 (!) weeks for Effexor to kick-in and help me to feel better. After about 3-4 months I started having headaches (normally I never get headaches) and heartburn (I'd never ever had heartburn in my life prior to Effexor). M 42 6 months
1/20/2005
 4  Bipolar I (depressed) post-suicidal Agitation, hand tremors, anxiety, sweating, increased blood pressure, complete loss of libido, extreme difficulty ejaculating At 375mg/day, it has brought me out of my suicidal depression. I hope to taper off of it and remain on Lamictal soon. M 40 14 months
1/21/2005
 4  Anxiety Depression Weight Loss 1.2 kg per week. Difficulty getting and maintaining an erection, difficulty ejaculating, sometimes not a problem. Night sweats. Lots of yawning at first but not tired, yawing now mostly stopped. Nausea at first but now mostly stopped. Appetite decreased, no interest in binge eating, loss of interest in alcohol and coffee. I feel like I think I should be feeling. Anxiety and depression are 85-90% gone. Big big improvement. Very happy to be taking this pill. Wish I was taking this years earlier. Nervous about coming off of it based on others comments plus I missed a pill one day and definitely noticed real mood issues surface, the next morning I woke up and realised I missed the previous days pill and realised why my mood the previous day was so bad. Very happy with the weight loss! I have lost interest in binging on chips and cheese etc... I still enjoy them but a reasonable portion is enough. I've lost interest in alcohol and coffee. Cut my coffee intake down from 6 cups a day to 2. M 48 5 weeks
75mg 1X day
10/7/2020
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 4  Depression anxiety Sexual side effects worst. How do u counteract it? Definitely works for me. M 51 10 years
150
11/16/2016
 4  Gerneralized Anxiety Disorder None while taking Effexor... Taper off slowly because the withdrawals are horrible, but I was able to do it over two months by slowly decreasing the dose. Finally getting off of it completely was the worst with brain zaps and dizziness but finally managed by taking my dose every other day for a couple weeks and then every few days until I felt well enough to stop. Dialectical Behavioral Therapy works way better than taking drugs, in my experience, because it teaches you the tools to take control of your life and your mind. Some people benefit from both but I would suggest trying DBT!! It's amazing. Good luck, hope this helps. Let's stop embracing fear and the pharmaceutical companies. You're in control, just have to find your way. M 27 8 years
300
11/17/2016
 4  ADD, depression, anxiety exessive sweating when sporting, sleep interruption My diagnosis was ADD with depression and anxiety, my main complaint was feelings of chronic fatigue. Having tried many drugs (stimulants, citalopram, escitalopram, Wellbutrin, sertraline and even Parnate), psychiatrists wanted to give up medication therapy. After much insistence the psychiatrist finally agreed to prescribe venlafaxine. And with success, finally an antidepressant that helped! Less tension, less social anxiety, less often sick and almost no suicidal thoughts. Especially in combination with sporting, I feel much better. Side effects are excessive sweating when sporting and every night I wake up halfway. I now take 112.5 mg (75 + 37.5 mg), if I take a higher dose I feel very sleepy. I took venlafaxine twice previously and when I felt better for a while, I quit. Reducing gradually went fine without any severe withdrawal. For tapering I used venlafaxine of the brand Bluefish (available here in Europe). The capsules do not consist of granules but of tablets with each 12.5 mg. Every week I took one tablet less and I didn’t experienced any severe withdrawal. Only at the end a bit of the common “electric shocks”, but I didn’t find it very disruptive, more like you had a glass of wine. M 35 4 months
112.5 1X day
6/20/2016
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 4  Panic Disorder/Anxiety/Depression Destroyed sex drive and erections. I could still get them but they were weak and short lasting. Miss a dose I got very weak, gained weight on it. Oddly I felt energized and sleepy at the same time on this drug. I'm down to 75mg xr after weaning down over a year. The longer you take to come down the better off you'll be with Effexor, don't try and drop it overnight. Most say it gets the worst when coming off completely, which is why I'm reluctant. The drug worked though, it helped me in all areas, ADHD, Deprssion, Anxiety, OCD...I'd go back up on it again cause I felt so much better and in control while on it. M 34 5 years
300mg XR 1X day
12/28/2016
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 4  depression M 60 12 years
75 MG 2X day
1/23/2014
 4  Depression While I have been on Effexor, I have identified side effects like asexuality - also, other sexual side effects; including: Ejaculation problems, and reduced climax intensity. There are also more mild effects on my sleep - Night sweats, and vivid dreaming. I do not mind these as they are not bad enough to be particularly unpleasant. M 18 1.5 years
300mg 1X day
12/8/2013
 4  anxiety/agoraphobia Premature ejaculation for the first time in my life. Extreme dry mouth, brain zaps, electric feeling when it's around time to take my dose. M 35 1 months
37.5
9/1/2014
 4  depression/anxiety Brain buzzing within 12 hours of missed dose. Less and less libido and sexual function over the years. Made my drinking into raging alcoholism. Detoxed and AA'd up and stopped smoking. Too bad about sex, alcohol and tobacco, I enjoyed them all ,but Effexor has really helped me. Now questioning if I should start tapering off and slowly transition to edible medical cannabis. Sounds like horrible withdrawal, as head buzzing suggests immediate pain and mental torture. M 59 14 years
150 1X day
3/16/2015
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 4  anxiety, ocd well, side effect wise, not all that bad. Sweating, high blood pressure, and somewhat agitated. also shaking bad after alchohol, for days that is. When i withdrawled the first time i cold turkyed it. it wasnt that bad, brain zaps mostly, but you people need to realize, NOT everyone gets the withdrawls, most people that come off it fine dont get on here to post how there withdrawl was ok, only people that complain do. Well, for all the ad's ive taken, i think this one has helped the most. i enjoy the decrease of anxiety that effexor has, compared to say zoloft, which zombied me, or generally just not giving a damn about anything. Im currently in the airforce so i have to deal with alot of things, and effexor has helped with that, so im generally really happy ^^. really i dont have much to say,sorry for all the people that have bad withdrawal symptoms, but it worked for me ^^ email me if you have any questions. M 21 9 months
4/17/2009
 4  Depression Blurry vision Decreased sexual sensitivity M 48 4 months
5/22/2009
 4  Depression Obnoxious behaviour, Increased talkativeness, nausea, diarrhea, headaches, insomnia, flatulence, depression, moderate weight gain, unable to achieve orgasm, increased sexual pleasure All of the short term side effects only lasted for the first 2 months,(sexual and weight problems manifested itself over the long term) except for the obnoxious behaviour and increased talkativeness. I don't think I still have obnoxious behaviour anymore (that's my personal opinion) but still talk more than I remember, but its no longer on an annoying level. One P doc has told me this may be because I had Dysthmia and SAD. The increased sexual pleasure only lasted for a couple weaks. Right now I have nothing to complain about with respect to this drug. It took me 6 months to get the correct dosage, which for me is 300mg. My psychiatrist specialises in using this drug, so was not afraid to carry me up to this level. I'm glad he did because once I try to step down, my symptoms return, even after 2 years. It is a Godsend. It lifted my spirits at a time when I could barely say a word for days because my mind was so blank. I couldn't keep my head up walking down the street because I though M 25 2 years
9/21/2008
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 4  Depressive/Anxious Insomnia,impared memory,diminished appetite,blurry vision. After 2 years of hell, this medication has given me some peace of mind, and cut out the lethargy that stopped me from my daily activitys.I have my energy back again,Insomnia is the downside for me.I wonder what the long term ramifications of its use will bring Given we need an average of 7-8 hour sleep within 24 hours. M 29 3 weeks
10/20/2009
 4  Major Depression Delayed orgasm Over the past five years, I've tried Prozac, Celexa, and Lexapro, all with no noticeable improvement. Actually, the first one I was ever on was Effexor, but only at 75mg. A few months ago, I started taking Effexor XR, this time a 300mg, and I can finally notice a significant improvement. M 28 5 months
12/30/2009
 4  SAD, GAD, Panic attacks, ADD, Sweating a lot, weight gain, sleaping a lot, chest pains. Brain zaps when missing a dose. Vivid dreams when going up or down in dose. Withdrawal was Hell. A lot of nausea and returning anxiety. I have used other ADs before, but EFX was the best one so far. I got it when i had severe panic attacks and anxiety. It also worked for my ADD. For the first time in my life i didnt worry a lot about the little things. I could be myself around other people. I felt confident. I went to the gym almost every day and i started to cook everyday. I started with 75mg and after that switched to 150mg and then 225mg. The 150mg made me feel the best but also made me tired and less motivated. After 2 years i decided to quit because of worsening of the tiredness, which was so bad at times i could hardly function. It took me 1,5 years to go from 150mg to 0mg. The first 2 drops from 150mg to 112mg and 112mg to 75mg where ok. But below 75 it was utter hell. I didnt make it to 37,5mg so when i went back to 75mg i was ok again, but i noticed the efx didnt work the same anymore. After 6 months i was so tired i couldnt get out of bed so i decided to quit the EFX in hospital. This time it went remarkably well and within 2 weeks i went from 75mg to 0mg. After that i had for about 3 weeks little bit of brain zaps and a little bit of nauseau and i was also a zombie at times. Now 9 weeks later i still have a lot of mood swings which for part is of quitting the EFX but probably also my ADD. Also getting my feelings back which i lost for the most part. I still feel my brain is adjusting to be EFX free. The tiredness is still there so i am already looking for other causses. M 32 3.5 years
9/20/2009
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