EFFEXOR XR Reviews (VENLAFAXINE HYDROCHLORIDE)

Average Rating: 3.0 (2225 Ratings)

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 ANTIDEPRESSANTS

 Type: Rx Drug

  

EFFEXOR XR  (VENLAFAXINE HYDROCHLORIDE):  Venlafaxine is used to treat depression, anxiety, panic attacks, and social anxiety disorder (social phobia). It may improve your mood and energy level and may help restore your interest in daily living. It may also decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Venlafaxine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain.   FDA Approval Date: 1997-10-20 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on EFFEXOR XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR EFFEXOR XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  BPD, PTSD, depression EXCESSIVE sweating at night, complete lack of libido, inability to orgasm, insomnia, nightmares, confusion, muscle soreness and fatigue so bad that I couldn't stand or do physical activities for days, absolutely DISGUSTING taste in mouth. Withdrawal: vomiting and diarrhea, brain zaps, incessant sensitivity/pressure down there (imagine your V swollen and throbbing like you're about to climax except you're stuck at that phase and experience no sexual pleasure from any of it). DO NOT accept this prescription. At all. If your doctor suggests this, ask for an alternative or switch to a less sadistic psychiatrist. F 28 3 months
75 1X day
12/22/2021
 1  Depression Going on is tough. Being in it is meh. And coming off holy heck even with a gradual taper I would not recommend this drug to even my WORST enemy. There's a reason they say Effexor discontinuation is worse than heroin withdrawals! F 27 6 years
225 1X day
8/4/2022
 1  Depression Horrible Nightmares Dizziness Drowsiness Lost appetite Increased Sweating No Libido Gained 20lbs - cannot lose Avoid this med at all costs. F 64 2 years
150mg 1X day
10/16/2020
 1  Depression/Anxiety Initially I became drowsy and laid down for a bit, but then when it really kicked in I was so dizzy I was holding on to the walls so I wouldn't fall down. My BP went through the roof: 170/90 and my anxiety did, too. Much worse than before. I not only lost my appetite, but I couldn't eat anything at all. Nausea and diarrhea, too. I called my doc and he said to stop taking it, but I was sick with these symptoms for 3 days even though the drug supposedly is out of your system 28-30 hours after taking it. If your doc prescribes it, ask about Celexa or Lexapro. These Rx are the second and third generations of Effexor. Far fewer side effects, softer on the system. I wish I had known this before I took it. F 67 1 days
75 mg 1X day
12/7/2020
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 1  Depression Low libido, increased irritability, more emotional at random times, headaches, horrible and vivid nightmares If I miss a dose, god help me. Brain zaps, mood swings, panic attacks, emotional breakdowns, nausea, fatigue, vertigo, irritation, depression, night sweats, more violent nightmares than usual F 22 1 years
225 MG 1X day
7/9/2021
 1  Fibromyalgia At first no side effects and my feet started feeling a little better after a week and i wasnt being a bitch but then after 2 weeks I started to get wicked tired and fatigue. I didnt want to clean my house did not shower or leave the house for 2 weeks . I honestly probably took three showers in two weeks.. Gross i know. Then the weight gain --Ť super hungry and i cant go to the gym anymore because my body kills so that pretty much sucked. Coming off it sucks even more. I feel like im tripping all the time. The nerves in my face go crazy my lip tingles and goes numb. Im having migraines from hell for a week straight. The night sweats are disgusting . i can not drive at night because it's causing extreme light sensitivity and blury vision. And sex... Is not even a thought . i recommend this drug to no one. F 40 1 months
75 1X day
11/20/2020
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 1  Depression/anxiety worsening weird thoughts, eyelid twitching,racing heart,palpitations, I have taken effexor xr in the past around 10 years ago had no problems with it then so I tried it again and now they say I'm allergic to it. F 46 2 months
35.7 1X day
12/3/2020
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 1  Anxiety, Depression Weight Gain (35lbs), Fatigue, Worsening Depression to the point of being suicidal. Felt no improvement but continued to take it just to prevent the withdrawal symptoms. The brain zaps were the worse. F 37 1 years
75 MG 1X day
8/27/2020
 1  Migraines 30lb weight gain, headaches and dizziness after 20mins of taking the dose, severe diarrhea all day, loss of appetite, burning eyes, hot flashes with extreme sweating, and swelling of my right Anxillary lymph nodes, fatigue My neurologist who put me on this drug does not believe any of my symptoms are related to this drug but if you look at my medical records I started rapidly gaining weight 3 weeks after taking my first initial dose. As the months wore on, I became unable to do anything as I would have either a headache or migraine every day and could barely do anything except chores in the house with many breaks throughout the day. It has killed my quality of life and I hate having to feel like I have the flu every single day! This drug should have a massive warning label on it about all the side effects it can cause including the very rare ones. Doctors need to research before putting patients on drugs that could make their disease worse. F 35 8 months
75mg 1X day
9/21/2020
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 1  Anxiety / Depression Difficulty swallowing, panic attack, heart racing, zombie like, no appetite, no sex drive, terrible heartburn, extreme lethargy, emotionless, dilated pupils, excessive sleeping, migraines, bruising, extreme hair loss - AFTER ONLY 3 DAYS!!! I was supposed to double douse after 4 days but couldn't image taking more of this and quit. F 37 3 days
75 1X day
10/5/2020
 1  Major depression disorder Mood swings, insomnia, depression, irritability, low libido, inability to orgasm, no empathy, suicidal thoughts, severe withdrawal symptoms: tremors, rocking, suicidal thoughts, crying, skin crawling, chronic illness, PTSD It worked to keep depression at bay for 6-9 months then I needed to raise the dose. I got by on 225 for a few years and didn't sleep for 3 days straight when we tried 300mg. Withdrawal was the worst thing I've ever been through, even with 9 months of microtaper and naturopathic support. It triggered trauma to my immune system and I ended up chronically ill. Thankfully a clean diet, mental counseling, and Chinese medicine have me feeling better after 4 years of cleaning up this mess. Quitting is possible; healing is possible; but this drug does severe long-term damage and can trigger other illness to tank your immune system. Do NOT go on this drug; get help if you need to get off. Don't give up. F 33 6 years
225 mg
11/10/2019
 1  Anxiety, Depression, PTSD I thought this really helped me at first. Numbing relief to extreme anxiety. I've wanted to stop taking it for nearly two years now but it's never the "right time" according to doctors... I don't think any doctor wants to be responsible for what happens when you try to come off of this drug, even slowly. I don't know what I'm going to do, I just want this drug out of my body but I'm so sensitive to the withdrawal that I'm afraid to do it... Even missing a dose within a few hours I feel so horrible I can't function and feel like I'm going crazy. Please don't let them put you on this... When you ask "so am I going to be on this for the rest of my life?" they don't give a straight answer. I feel like a lab rat they've tested this on F 23 5 years
150 1X day
12/29/2019
 1  Anxiety, Depression Did work for the anxiety and depression though I felt a but numb...missing a dose caused horrible vertigo and nausea. I developed tingling and GP recommended I come off it. Withdrawals are awful! Stopped cold turkey on doctors advise as there is no lower dose. Felt like I had the flu with no fever, sweats, shakes, pain,nausea, vertigo when i moved my head or eyes, horrible unwell feeling. 6 weeks off and over most of the symptoms but still have leg pains/cramps and sometimes they tingle and burn. Doctor said the withdrawal should only last 5 weeks so hopefully it won't be much longer. Horrible drug that should be taken off the market. Not enough research on the withdrawal effects. F 38 3 months
37.5mg 1X day
2/21/2018
 1  Severe depression Effexor is one of the worst things that ever happened to me. I can't tell you how many times I almost pulled the trigger. Oh and if you leave it at home/don't take it for a day, be prepared to feel absolutely horrible. Double vision, confusion, extreme depression I could go on and on. And getting off of it? The hardest thing I've ever had to do. I still can't believe I didn't kill myself. Please don't take this drug.... F 21 14 months
30?
10/30/2017
 1  Depression/Anxiety This drug is HORRIBLE. I was on Wellbutrin & Celexa for 16 years. Tried to get off both twice (on my own) and was a mess. I don't think I tapered down slow enough or gave the emotional roller coaster enough time for my brain to heal. The last time I tried to stop the antidepressants I went to a new dr. who put me on Effexor. He was basically running a pill mill and told me I needed to be on these for life. Disgusting man. Well, now I'm on Effexor (225mg) and Wellbutrin (300mg). Within the last month I noticed I am losing hair - a lot of hair!!! I'm also experiencing anxiety, agitation, fast heartbeat, vision changes, tremors, acne, muscle jerks primarily in my legs, memory loss, and my period is out of wack - I have it every two weeks or more now. I'm 50 so I figured some of these were age related, but after researching more about Effexor I think the AD's are to blame. The hair thinning is the last straw. I'm getting off this shit and then will tackle getting off the Wellbutrin. I originally got on AD's when I was going through a very nasty divorce 18 years ago. I NEVER should have gone on them - and now I can't get off them without a ton of awful withdrawal effects. And I'm terrified that my brain is forever altered. I hear Effexor is one of the worst to come off of, although Celexa was horrendous with the brain zaps. These AD's are TOXIC. I am looking into going to a rehab center to have medical help to get off both of them. I pray to God that I can get these antidepressants out of my body and that He will heal me. F 50 1.5 years
225mg 1X day
4/15/2018
 1  panic, GAD Decided to try this since my brother takes the regular version for OCD. I took my first dose at work and it messed with my memory. A cop left a message with with me but I couldn't remember what he said when I relayed the message to my boss. Next, I felt feverish and brain zaps the entire time I was at work. When I got home, I couldn't pay attention to what anyone was saying. I had to try extra hard to remember how to make a pizza!! It nearly killed me memory. At night, when I was sitting on the couch, I felt pretty anxious and paranoid. I got even more anxious for feeling paranoid. That night around 12 am, I woke up drenched in sweat and in state of confusion and panic. I had to take .5 mg of Ativan to calm myself. Works like a charm for my brother with NO SIDE EFFECTS, but with me, I got every side effect in the book. I took a sample of this drug in high school before going to bed. All I remember is getting insomnia. This drug is not for me. F 33 1 days
37.5 1X day
9/1/2018
 1  Postpartum depression and anxiety Zaps that feel like you are being electrocuted briefly then immediately followed by vertigo and a sharp headache. Would happen any time I was a little late taking a dose and asked to come off of it and now the zaps occur every 45 seconds and I'm only on the first week of trying to come off. The only thing that helps these symptoms is taking more of this drug. It is not a side effect, it is withdrawal! Never would have started taking it if I knew I would go into withdrawal. This drug did not help with my anxiety. The side effects (aka withdrawal) actually make my anxiety worse because it is a very scary feeling. I literally cannot function trying to come off this medication. F 30 3 months
75mg
5/15/2020
 1  Depression Absolutely worst medication I have ever been on. I thought it was working at first but then around 3 months in I started to notice horrible changes within myself. I was profusely sweating. I would not want to leave my house so I started to miss work. I became extremely paranoid. I became homicidal. I was basically a zombie. It was very scary. I literally feel traumatized from the effects it had on me. F 34 4 months
150mg 1X day
7/20/2020
 1  Depression, anxiety, ocd severe nausea, shaking, extreme dizziness, vertigo, increased anxiety, extremely vivid dreams, nightmares, sex dreams, very hard to wake up, headache, difficulty sleeping, worsening memory, hard to think, brain zaps (feels like a shock running through your head) I’ve heard that it works miracles for some, but that was NOT the case for me. If you are thinking about taking it, research and know what you’re getting into. It was extremely difficult to ween off of, even when I was down to taking a few little beads from the capsule at a time for months and months.The side and withdrawal effects were absolutely miserable, and I feel like it did something permanent to my brain. I had to use a Prozac “bridge” to get off because it was too difficult alone. My memory is horrible now and I shiver from anxiety when I never did before, and I’ve been off of it for about a year. Did not seem to help my anxiety or depression at all. If I was even thirty minutes late taking it, I would feel horribly sick and shaky for hours. It would make me so dizzy that I had to hold onto things to walk around at work. The symptoms were there even when I wasn’t late taking it, but much more severe if I was. F 21 1 years
150 mg
8/10/2020
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 1  Anxiety and depression Worst heartburn of my life My doctor told me to try to take Prilosec with it but that gives me a dry cough. I tried Pepto and it did nothing. My whole chest was burning. I couldn't even make it through a week. F 40 3 days
37.5 1X day
6/15/2020

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