LAMICTAL Reviews (LAMOTRIGINE)

Average Rating: 3.4 (1917 Ratings)

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 ANTICONVULSANTS

 Type: Rx Drug

  

LAMICTAL  (LAMOTRIGINE):  Lamotrigine is used alone or with other medications to prevent and control seizures. It may also be used to help prevent the extreme mood swings of bipolar disorder in adults. Lamotrigine is known as an anticonvulsant or antiepileptic drug. It is thought to work by restoring the balance of certain natural substances in the brain. This drug is not approved for use in children younger than 2 years due to an increased risk of side effects (such as infections).   FDA Approval Date: 1994-12-27 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by Gender with females listed first (reviews with no gender reported listed before females).

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on LAMICTAL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR LAMICTALCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Depression not responsive to ssris Increased depression, rages, irritability, paranoia, painful body, speech and memory issues. Lethargy. Fog like. Very rapid cycling between sad and angry. Zero happiness and worse teeth clenching F 39 7 weeks
50
3/23/2013
 2  Bipolar 2 Do not take this stuff unless you want to feel like an emotionless zombie floating thru life and never really enjoying it. I'm trying to convince my psychiatrist to take me off of this medication cause I really want to feel like 'myself' again. My outgoing personality has vanished and I have no motivation or anything that makes me feel 'truly' happy anymore. Even sex has lost my excitement. I can't wait to get off this stuff and get my personality back!!! F 19 3 years
300MG 1X day
7/6/2012
Email
 2  Issues with stabilizing moods Fatigue, irritability, mood swings, emptiness, increased sexual urges, inability to fall back asleep after waking up spontaneously, waking up with sore neck, occasional sore throat, carelessness, confusion, lost of interest. I have been taking the generic form of Lamical (Lamogtrine) for around 2 months. At this moment in time I feel as if this drug has ruined my life! I had problems with depression and stabilizing my moods before taking Lamictal, but I was relatively sane compared to how I am now. Firstly, I am very empty and feel that my existence is zombie-like. I don't have any sense of compassion or sympathy. I've been with my boyfriend for almost ten months and we had such a strong relationship before this medicine, but now we almost go our seperate ways three times+ a day because I never seem to be able to make up my mind. I was paranoid that he was going to leave me prior to Lamictal, but now the tables have turned completely and he's trying to keep a hold on me but I fear I'm going to do something stupid. I go from loving him, being so infatuated, convinced we're going to have a future to doubt that we're going to last and I'm unsure if I love him or even care about him at all. It's a horrible thing to admit and I'm ashamed I don't have a grasp on my own emotions anymore. I am so confused and just want to remember how I felt before taking this terrible medicine. I was so sure that I was going to become a fitness trainer/nutritionist, and carefully controlled what I consumed as well as tried to keep fit...I had DREAMS...GOALS! But now, I don't even attempt to stay healthy or trim. No career seems to appeal to me, and nothing really entertains me anymore. Things I once loved and had intere F 17 2 months
25-50 1X day
8/22/2012
Email
 2  Bipolar Metalic taste in mouth, Severe gas, chronic diarrhea, dizziness with loss of balance, sinus pain with rhinitis and thick mucus that dropped to back of throat, headache, pain in fingers and hands, flu like symptoms and increased facial acne that was never an issue before, feeling completely sick, miserable and "toxic" physically. Once I increased the dosage from 50 mg to 100 mg I started to literally feel toxic. My MD decreased my dosage back to 75 mg and told me that I obviously had the flu since the dosage wasn't therapeutic level and not enough to affect an infant. I resumed the 75 mg dosage and immediately began feeling sick again with all the same symptoms. After 3 days off the medicine I began to feel somewhat normal again, so I know it was the Lamictal. This was a great mood stabilizer that left me feeling much better emotionally, but with the terrible side effects it's impossible for me to remain on the medicine. I'm discouraged and doubtful that I will ever find another medicine that was as effective at stabilizing my mood. With the adverse side effects that are reported here, I don't think the toll on my health is worth the risk. F 49 2.5 months
10/30/2006
 2  depression, possible Bipolar 2 headache, night sweats when increasing dose, extreme fatigue, some weight gain. I felt great for the first three weeks (at only 25-50mg) and then proceeded to get sleepy as I increased to 200mg. At that point, I couldn't stay awake for more than an hour at a time, couldn't finish my school work, and almost had to drop out. Am just off it now, has been quite difficult to get off. Lamictal is a serious med... make sure your Pdoc thinks you really need it for depression if you're not certain of Bipolar. F 21 5 months
5/21/2006
 2  depression nausea, itchy skin, vivid dreams, tender and swollen breasts, increased menstrual pain/pms, hot flashes, sinus, feeling like I was having morning sickness, again. I will discontinue the Lamictal, I can't deal with the "female" side effects. Pdoc has kept me at 25mgs to see if I will adjust. My depression is lifting, maybe due to wellbutrion. F 46 1 months
10/17/2006
 2  bi polar 2 AGITATION! acne, night sweats, headache, short term memory loss, distractibility, difficulty with words, especially names, and hallucinations Side effecs got worse as I got higher up in dosage. About a week after I got up to 175 mgs, I developed the worst agitation of my life, a really, really unbearable feeling. Lamictal may have triggered hypomania in me. Actually had hallucinations one night. Will be discontinuing this medication. I seem to be unusual in having had this response to the drug, but anxiety and agitation are reported as "very rare" side effects, even in the official company literature. Also, women be cautious-- Lamictal interacts with birth control pills in ways nobody seems to understand very well, so do some research and ask your doctor about it. F 31 2.5 months
4/8/2006
 2  Bipolor Severe Headache, Feel numb wanting to isolate myself from my family,Feel sick at stomach no appetite, Feel as needles are poking into my arms.Elevated Blood Pressure,I have been on meds now for 3 years and this one is making me feel dead. F 30 5 weeks
4/9/2006
 2  Bipolar Severe Headache, Feel numb wanting to isolate myself from my family,Feel sick at stomach no appetite, Feel as needles are poking into my arms.Elevated Blood Pressure,I have been on meds now for 3 years and this one is making me feel dead. F 30 5 weeks
4/9/2006
 2  BP and major depression Increased depression, aggressive behavior, sore throat, NEVER happy, nightmares F 39 14 days
9/27/2005
 2  bipolar none, everything ive experienced has been because of the activities i do...ex: muscle aches well, its hard to say bad or good stuff about this med, find i am still angry but i dont have the impulse to throw something at someone, let alone kill them. on good terms, kind of, i have been able to keep in touch with my creative side since i missed out on plenty of that since i have been fucked over with medicines(music and art, i love piano and drums) but i still cant stay home and be with the people that i love and i still have my substance abuse issues even more than ever....gosh i guess it depends on...SO many things...i just still feel ANXIETY!!! i cant go into places where i should feel comfortable. i dont know what to say, im glad im able to get out of bed but man, i swear it's almost letting my creativity go TOO much, all i ever feel like doing is jumping around and say F YOU to everyhing,..........DAY 17. no mania, no depression, no nothing except wanting to abuse substances, keep in mind i was doing VERY well with drinking and i totally stopped everything else.. F 21 17 days
3/23/2006
 2  Bipolar 2, depression&anxiety too Feels like warm needles being put into my legs once in awhile, nasuea, lack of sleep, more anxiety, depression is worse. Atleast no weight gain...Ha! It has however, taken away any 'highs,' joys, and zest for life that I've had. That 'one good day' in the past 7 months left me wondering if it was 'a good day' or 'fake high.' Very sad. I am now only going out of house after dark or wearing sunglasses if I have to go out in the daytime. My adult children call them my 'magic glasses!' HA! I hate this disease. God never allowed me a great deal of money, He was afraid I'd be the one to buy 50 shoes at once! lmao I take 200 mg, and 200 Zoloft, I have had one good day in the past seven months. Aniety increased now to point of being scared to leave appt., can't work. Now they have me on Seroquel, and also Klonopin. So add premarin, and pepcid and I feel like a walking med cabinet. Taken Zoloft since 18. Before this last bout of depression, was vibrant, alive, could function. F 50 7 months
3/8/2006
 2  Epilepsy I bagen with new onset seizures on August 5th. I was started on Trileptal first then weaned off of that and "ramped"up on Lamictal since. I have had 2 more seizures since starting the Lamictal. From 1 to 3 in over one month is not accepiable to me. I wish I would have just stayed on Tripletal. Also, my memory is very poor (not good as a nurse) and I have trouble with word finding. F 26 6 weeks
9/23/2006
 2  Bipolar 2 Pancreatitis, urinary urgency and incontinence In Aug. 2005 I posted to this site describing Lamictal as my miracle drug, saving my life. Well, here I am 7 months later and almost one year of starting Lamictal. I was just discharged from the hospital for treatment of pancreatitis. The MD in the hospital suggested that the cause may be the Lamictal because no other cause could be found. I begged her not to discontinue my miracle drug. Well, when I got home I researched the Lamictal and found that pancreatitis can be a side effect. The FDA website states there is no percentage of prevalence but it does happen. By the way the pancreatitis occured within 2 weeks of increasing my dose to 300mg. Also, I had been experiencing urinary urgency throughout my therapy with Lamictal (I felt it was a small price to pay for feeling "normal"). Within one day of being discharged from the hospital I was in a major dept. store and I was totally incontinent of urine. Imagine the humiliation !!! Not only was I confused and embarras F 54 1 years
3/27/2006
Email
 2  BPD, Depression, mood stabalizing Started with 25 mg now I'm on 200mg, Acne, IRRITABILITY, clumsiness, WEIGHT GAIN! (the worst, i went from 120-127 within in 1 month and im still gaining, I cant even lose any when i starve myself), Anxiety, Hopelessness, INNABILITY TO FEEL EMOTIONS, UNABLE TO ENJOY MUSIC OR ART, UNABLE TO TELL WHATS REAL FROM WHATS NOT, since i went from 100mg to 200 mg the deppresion is starting again. Side Effects are worse than benefits. F 17 1 months
11/30/2006
 2  Depression & Panic Attacks Explosive Anger, Mood Swings, Withdrawn from Family, Memory Problems, Increase in Weight, Vivid Dreams, Irritabilty I have been on every drug you can imagine to help me with my depression. Nothing seems to work. I am currently on 150 mg Effexor, 50 mg Trazadone, and Zantax ( when needed). I started taking Lamictal because I am still depressed. I didn't notice anything ( execpt vivid dreams) until 75 mg. At 75 mg...I started screaming at everyone and punching holes in the walls. My shrink wanted to up my dosage. I tried 100 mg for a week and things just got worse. I want to find something that helps! I have started on a 3-4 mile a day exercise program which has really helped with the anxiety but I still have depression. F 31 6 weeks
10/17/2006
 2  bipolar and seizures Cognitive: Decrease in memory, difficulty focusing, difficulty spelling, numerous errors when writing detailed information, clumsy. F 43 18 months
9/17/2005
 2  depression, post traumatic stress I am on day 10 of this medication. I was so incredibly tired the first week,and after reading some comments on this board, I started taking it at night. WHich helped with that a little bit. Today I awoke with an odd headache, and I am headache sufferer anyways, and nausea. Upon reading these comments and how I feel today..screw it.,,Im not taking it..I already feel too many things wrong here. Good luck everyone else. But getting excessive weight, acne,headaches, memory loss..not worth it. I would rather be in a bad mood. Ive now resolved myself to the idea that there is no cure from a magic little pill that doesnt come with some baggage, and I need to look within myself for the help I need. F 37 10 days
4/22/2007
 2  depression possible bipolar cold sores, headaches, achiness, sore throat, flu-like symptoms, anger, agitation, irritable,anxiety did fine on 25 mg.s for 2 weeks. when dose increased to 50 mg.s , side-effects were intolerable. dr. told me to stop meds. F 41 18 days
10/31/2006
 2  bipolar I 9 days into taking only 12.5 mg/day (in combination with depakote-- I was tapering off the depakote under Dr's supervision), developed itchy rash. Dr. has advised stopping Lamictal. Rash started at ankles, 1 hip, got worse overnight on ankles/feet including soles of feet. spread up both thighs. In most places it looks like very small pink dots, sometimes with a paler "halo" around the dot. (I am fair-skinned.) A few areas on my feet are blotchier. Also, I have some significant soreness/stiffness in my neck that began the afternoon before the rash started. It would be helpful if patient inserts included photos of what lamictal rashes look like. F 31 9 days
11/3/2006

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