WELLBUTRIN Reviews (BUPROPION HYDROCHLORIDE)

Average Rating: 3.2 (1230 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on WELLBUTRIN: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR WELLBUTRINCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 2  Depression and Anxiety Sweating, suicidal thoughts, NO SEX DRIVE F 45 3 years
5/28/2009
Email
 2  Depression (dysthymia) Shakiness, insomnia, nausea, headache/pressure feeling on and off in eyeballs for first week or 2, feeling of sadness or something like dread in the pit of my stomach, etc. I'd been on Prozac for too many years, and it's stopped working so the doc decided to try me on something new. After a bad trial run with Abilify (GOT FAT), he put me on Wellbutrin XL 150 mg. x 1 daily. First week: my main problem was insomnia and startling awake at night. Second week: still no relief from depression; my vision got blurry one night when watching TV and I thought it was just fatigue. My eyes felt the same the next day and I began to get a headache. That freaked me out as I know that's a sign of high blood pressure, which could be a side effect. My bp was fine, so I decided to stick it out for a couple more weeks. I am now in week # 4 and the main issue I'm having is this constant anxious sick/dreadful feeling in the pit of my stomach. Still no relief from the depression... I may give it another week before I switch to something else. I'm just a little wary of the withdrawal from this drug and the prospect of starting all over again with something new (been there, done that!) F 45 4 weeks
4/20/2009
Email
 2  Depression and ADD Minor buzzing feeling, Severe Hives I loved this medicine - it made me feel normal and helped my depression and ADD symptoms right away. I was happy and not depressed and able to get things done. Then after two weeks I developed external (itchy rash and swelling) and internal hives (throat got tiny, felt feverish) and had to take Benadryl to alleviate the symptoms until the drug left my system. My doctor had me take Prednisone for five days as a result of my allergic reaction, too. I was really bummed. Until I developed the severe allergy I felt great and really loved Wellbutrin. F 36 15 days
5/5/2009
 2  depression/fatigue/ADD symptoms Worst acne of my life My experience exactly mirrors this writer's: ". . . I was able to feel energized and 'normal'. BUT, then the nasty side effect kicked in. After about a week and a half of taking Wellbutrin I began to break out with horrible acne, some of it cystic. I felt I couldn't leave the house because of it. I went off this medication and my skin cleared up in a few weeks." F 42 2 weeks
8/12/2009
 2  depression, OCD, anxiety/social Aggression,rage, extreme fatigue, apathetic, withdrew from social situations, crying all the time, inability to concentrate, migraines with nausea,anxiety,restlessness, autopilot and boredom. No problem sleeping, it gave me no energy I have tried just about every med for depression. The only one that did any good was Paxil and it wasn't enough. I would come home from work and scream at everybody.i didn't realize, my husband pointed it out to me, as well as other family members. I just want to feel some sense of normal. It did however, make me a lil more assertive F 30 4 months
200 mg
1/19/2015
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 2  substitute for prozac to lose weight I haven't lost a pound, I feel more depressed than before taking this pill I have dry mouth and a terrible taste in my mouth.150 F 70 30 days
150 2X day
12/13/2014
Email
 2  severe depression At first it gave me Energy .I take prozac 20mg with it. I did good for a week then started fatigue crying within 10 mins of taking them. My Dr lowered dosage an it worked for a little while. Now I'm back to crying fatigue depression worse. Awful dreams. Crazy thoughts an absolute paranoia.going to Dr tom to talk about it. I really wanted the wellbutron to work as over the years I've had to change my meds quite a few times. F 57 4 months
150mg1/2 3
8/18/2014
 2  Depression Day 1: Felt high as a kite. I was very restless & anxious and had difficulty sleeping. Day 2: Still felt high & unable to function. Extreme anxiety. Day 3: Not as high, but more like the feeling of being down from a high, but "under the influence". Extreme anxiety. Day 3-6: Feeling stoned. Brain fog. Unable to carry on a normal conversation. Feel more depressed than before the meds. Feeling of complete deadness inside, severe anhedonia, anxiety not as bad, but isolated panic episodes. (Anxiety was not a problem before wellbutrin) Not feeling "right" or " normal". Crying a lot. Day 7: Cannot continue this medication. A lot of people on forums say it will get better, but I cannot live or function another day feeling like this. My depression doesn't seem so bad now after feeling like I felt after 6 days on Wellbutrin. I do think that my experience is not typical though. I was taking generic wellbutrin SR 150mg twice daily. F 37 6 days
300mg
4/12/2015
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 1  To compliment Zoloft and lose weight Good God! One night of hell! I didn't read the side effects first. My stomach hurt soooo bad, and yes I had food with it. I got hives all over my arm, the side from breast cancer lymph node extraction. Vomited all night long.... very sick now, agressive, agitated, and that's from one pill. I think I will tell my doc that this experiment was a fail. Maybe more research is needed for the use with cancer patients, I just don't know. F 53 1 days
1 pill
4/25/2015
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 1  depression/anxiety abdominal pain, diarrhea, insomnia, loss of appetite, nervousness, tinnitus, dry mouth, heart palpitations, weight loss I had taken this medication 8 years ago and had no side effects from it. This time though I had a negative experience with this med. I had constant diarrhea, 3-4 times a day. I had a loss of appetite and had gotten to the point that I couldn't stand to even think about food. Thinking about what to eat or fix for my family actually caused anxiety. I lost 10 lbs in 9 nine days. About the 5th or 6th day I started to be unable to sleep during the night. I woke up every hour. During the day I would have waves of nervous energy, almost like the feeling you get when you experience the fight or flight response. The last day I took it I woke up at 4 am with diarrhea, left sided abdominal pain that radiated to my back and shoulder, and heart palpitations. A trip to the ER revealed that I had a large amount of stool and gas in my colon. I had a miserable experience with Wellbutrin. F 39 9 days
150 XL 1X day
7/18/2015
 1  Major Depression Started with 150 XR generic to "augment" Prozac (40-60 mg daily for ~2 yrs), not exactly sure why I was even looking for a boost -- undergoing significant extra stress, in summary. I asked to increase to 300 mg within a week or two ... again, not quite sure why. To intensify its expected "feel good" effect, I guess. Knowing it is a dopamine enhancer, I was aware it would stimulate pleasure centers formerly activated by drugs and alcohol. In short, it does indeed appear to be a faux cocaine, although the high wasn't near even the rather lame high of cocaine yet the adverse effects were strikingly similar if not yet out and out as dangerous. Within two weeks of 300 mg XR, I quit taking Prozac because I believed it to be the cause of my fatigue. I figured the Buprion would keep my mood & energy up on its own. DEAD WRONG. I became reactive, aggressive, angry, lashing out, having rageful outbursts...yet i attributed this to my underlying depression itself and stayed the course believing the drug would help me. Excruciating abdominal pain one day. Vision beginning to experience faint tracers, which is terrifying to me (WTF!!). PRONOUNCED short-term memory loss! Immediately forgetting what I was just about to do or had just done (no thank you!!!). WORD CONFUSION -- I meant to say one word and a random word popping in my mind mid-speech would come out instead (loss of control of one's speech -- GREAT!!!!). CRYING OUTBURSTS began almost immediately even on the good to feel your feelings, but...). As so many others have reported, my DEPRESSION WORSENED. My psych doc (NP) said this was a possibility if I stopped taking the Prozac. **EXTREME** FATIGUE, IMMOBILITY ("asthenia") just about THE WORST effect of all. Oh but wait--then there was the creeping DESPAIR, HOPELESSNESS, BLEAKNESS AND BORDERLINE SUICIDALITY THE LIKES OF WHICH I'D NEVER EXPERIENCED BEFORE. AND MASSIVELY ACHING ALL OVER. NEVER ACTUALLY FELT "UP," JUST INCREASINGLY DOWN, DOWN, DOWN. I, like many ppl on these sites, quit cold turkey today. Fearing withdrawal, the only difference I've seen, besides no change yet in the OVERWHELMING FATIGUE, is a RETURN TO BETTER MOOD AND RESTORED CLARITY. I don't even want to return to Prozac. This was such a HORRENDOUS RE-LIVING OF WORST DEPRESSIVE OVERTAKE that I am determined to restore myself with CARE & RECOVERY. That entails taking the mind/body/soul REST that I need, tending to my FEELINGS, and dropping burdens and stressors. More healthful eating & exercise will come as self-love grows to _naturally_ motivate me to further my sense of well being. I will keep the SSRI on the shelf in the event the engulfing phantom of DEPRESSIVE mood disorder returns, but I am going to cope with my own devices first vs. coping with the comparable roller coaster of medicating this condition. It has been eye-opening and VALIDATING to read everyone's testimonies. WE ARE NOT ALONE. SHARED STRENGTH & COMPASSION. BLESS. F 44 1 months
350 XR gen
7/13/2015
Email
 1  Depression I'm going INSANE. I was originally on 150 mg and started to feel really bad, my worst symptom at that time was anhedonia (not caring about anything). All I felt was sadness and loneliness, even with my boyfriend, friends, and family. It didn't even cross my mind that it could be the Wellbutrin because my side effects coincided with some negative things that happened to me. So because I was feeling so low, a week ago my psych changed my dosage to 300 mg. And it seriously feels like I'm dying. I can't eat, I forced myself to today but yesterday all I could stomach was a handful of trail mix. I can't sleep, even though I take sleeping medication. I'm rapid cycling through moments of severe depression and occasional moments of what I would probably call mania. Yesterday I was semi-delirious because I didn't eat and hadn't slept, and severely paranoid. I kept picturing that an earthquake was about to happen, and then I kept experiencing it over and over in my head. My psych is weaning me off of it completely right now, 5 more days to go, and the end of this nightmare can't come fast enough. I'm praying these days fly by. F 22 3 weeks
300 mg
12/2/2015
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 1  ADD- stop smoking, menopause 1st day I was so high and disconnected from everything so tired Day 2 dry mouth again felt so high I couldn't function Dr said switch to bedtime. Day 3 by afternoon I felt better when I took the pill again it started all over I'm in my 11th day and I'm not sleeping im not eating I'm depressed crying, in a rage, or zombie like just sitting and staring feeling nothing Dry mouth, stomach pain racing thoughts can't concentrate can't hold a conversation I feel Crazy Dr wanted me to try this said it would help with everything like some wonder drug Prior to starting the medication I was not depressed Tonight as I sit here I feel so worthless alone so empty I can't think and when I do my mind just races I want to sleep and I can't This medication has made me a mess F 45 10 days
150
12/21/2015
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 1  Weight loss Blurry vision, high blood glucose, irritability, sleeplessness, Low energy, and muscle tightness I began to lash out at my spouse, my vision was so blurry I could not see very well at all. My husband is a diabetic so I decided to take my blood sugar, it was 137 fasting. That is high for a me, I am usually normal. It remained high, so I went off Wellbutrin, my vision has cleared and my blood sugar is back to normal. F 57 2 months
150xl 1X day
1/7/2016
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 1  depression Shaking and excessive sweating and very dry mouth and easily agitated. F 52 2 months
100 mg
4/4/2016
 1  Depression Seizures and suicidal thoughts. Always walking around in a fog I believe this drug is horrible and should be pulled off the shelf F 25 8 months
20
5/6/2016
 1  Depression Anxiety, paranoia, auditory hallucinations, withdrawn So before taking Wellbutrin, I was taking Prozac, which made me extremely sick and I was nauseated, the worst burning stomach pain of my life, and barfed for 24 hours. My doctor then prescribed me Wellbutrin which was SO much worse than my side effects of the Prozac. I started getting extremely paranoid that someone was breaking into my house, which only got worse over time. I then started having auditory hallucinations and I would hear banging on my windows and doors, foot steps on floor inside my house, and a man whispering things like "I'm going to kill you" or saying my name. I ended up hiding in my bathroom with a knife and called my dad while he was at work and told him someone was breaking in the house to kill me. He left work immediately and had to talk me into opening the door for him to come inside. And when he found me I was curled in a ball screaming and completely hysteric. I continued hearing things, and thinking someone was coming to kill me for four days after that, and then the symptoms started lessening. For anyone who experiences these symptoms PLEASE DONT TAKE IT LIGHTLY. I have since seen a psychologist who told me that the side effects I experienced on Wellbutrin are side effects people with Bipolar Disorder ecperience, and I have now been diagnosed with Bipolar 2 Disorder. So, keep in mind that you may not have depression, and these side effects may mean you have Bipolar Disorder, so PLEASE talk to someone about this. F 21 5 days
8/25/2016
 1  anxiety/depression I was on 20 mg of lexapro for about 2 years. All of a sudden it stopped working, and I gained about 15 lbs in 4 months. My doctor decided to switch me to the generic of wellbutrin. I also take meds for hypothyroidism. I started with 150 mg for the first three days and the first day I didn't feel any different. I could already start to feel the effects by the second day...And they were not good. Once I moved up to 300mg of felt absolutely awful. I was nervous and my whole body felt jittery. I could not sleep for about the first two weeks...And eating? Well forget about it! I was constantly sick to my stomach and would throw up several times a day. With in the first two weeks I lost 10lbs. I had horrible constipation, but I will spare the details! My head felt like it was in a constant fog and I couldn't focus in anything. It also gave me horrible headaches. I know it can take a while for an antidepressant to work so I'm trying to hold out. My doc lowered my dose back to 150 mg a day, but I am still throwing up atleast once a day. My moods are crazy! Sometimes I just want to cry all day, and other days I am just plain mean. I just want to feel normal again!! My doctor said we might have to change my meds again, and that terrifies me because that means hell starts all over again. At this point I feel so bad every day it's like I'm living in a constant hell...so what could it hurt to try another one! Right? I really wanted this one to work because of the low sexual side effec F 28 1 months
300mg
9/17/2014
Email
 1  Depression and anxiety Nausea, headaches, severe mood swings (super happy to suicidely depressesed), severe sensitivity to sounds- even quiet chatter, couldn't concentrate, apathy, extreme paranoia, constant need to sleep- even when I wasn't tired, severe panic attacks that lasted days instead of an hour or two, constant insomnia, extreme fluctuations in body temperature, my feelings shifted from ravenous hunger to vomiting at the thought of food. Thank god my family was looking out for me and took me back into the doctor. He stopped the Wellbutrin immediately. I thought my anxiety and depression were just overcoming me, I didn't realize everything I was going through was a severe side effect of the Wellbutrin. I have been off of it for a little over a week and I am finally beginning to feel a bit more normal. I thought I was losing my mind. I have never been so close to checking myself into the hospital for a psychological evaluation before- I was terrified of what was happening to me. I will never take another drug without reading the side effects first. Be careful when taking this medication. Make sure you have someone you trust watching out for any unusual behavioral changes you might experience. For a lot of people this medication works wonders, but make sure you are discussing any changes in your mood with your doctor. F 36 5 months
50mg 1X day
10/5/2014
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 1  Depression Severe nausea, dizziness. Increased severity to vertigo, vomiting, severe migraine, extreme body temps. Unable to move, speak very very well, shaking and twitching. I ended up in the ER. F 32 7 days
100
11/10/2014

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