PREDNISONE Reviews (PREDNISONE)

Average Rating: 2.5 (617 Ratings)

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PREDNISONE  (PREDNISONE):  Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions.   (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PREDNISONE: Reviews Summary  |  FDA Adverse Event Summary

RATING  REASONSIDE EFFECTS FOR PREDNISONECOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Poison ivy Anxiety, depersonalization, vertigo, insomnia Took 40mg for 5 days then slowly tapered off for severe poison ivy reaction. The 40 mg was terrifying and put me in a dark dark place.. Never again. Worst experience of my life. F 65 20 days
40 1X day
6/26/2026
 1  Sinus infection Had to go to ER two days after stopping because of tachycardia and hypertensive crisis. I don't have heart issues. This was 8 weeks ago and I still have an elevated heart rate and blood pressure on and off, especially when anxious or stressed. I don't know when this will stop. I was only on it for three days. Doctors are skeptical about the effects lasting this long with such a short course, but I am not imagining things! It shouldn't be prescribed unless there are no alternatives. F 68 3 days
40 mg 1X day
5/30/2026
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 1  side effect of gabapentin After taking prednisone as needed for 4.5 months (total 1260mg, min 5mg, max 60mg), I suddenly developed severe throbbing in my brain causing acute chronic insomnia. It came out of the blue, no warning signs, no gradual onset, just instantly after taking 40mg one morning. 9 months after discontinuation and it is still going strong. Every single night I have insomnia. I cannot stay asleep for more than two-three hours. It has spread to my heart, abdomen. Sometimes I don't sleep. My cognitive abilities have significantly decreased: I can no longer do research or play chess. 2 months after discontinuation, 6 dents formed on skull, and are still there. 3 months later, I started having dry eyes. Now I am developing further neuropsychiatric symptoms, including depression, moods swings, mania, migraines.. also muscle weakness, acne, oily skin, worsened my preexisting photophobia. While on the drug, I had suicidical ideation and felt I lost my personality for a full 5 days. This drug is extremely dangerous and doctors prescribe it in the most irresponsible way. The side effects that are usually mentioned (fluid retention, osteoporosis) hide much more severe side effects that can permanently damage your brain (as supported by the scientific literature, which my prescribing doctors failed to warn me about). Even if you don't develop side effects on the drug, you can develop serious ones months later. DO NOT TAKE THIS DRUG unless you are in a life-threatening situation, no matter what dose your doctor give. Even then, I would rather die. It doesn't solve anything and jeopardizes your long term health. M 36 4.5 months
5-60mg 1X day
9/16/2025
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 1  GCA. PMR Taken for 2.8 years for GCA. It has wrecked my life. Very quickly attack on bones, cartilage, tendons etc. Inducing ostioarthritis everywhere, facet joint breakdown, Scoliosis, ostiopenia. Left in a lot of pain, and now affects my walking. Side effects.. insomnia, psychosis, blurred, and double vision, silent migraines, anxiety, depression, bowel impaction, suspected heart attack, heart rate 180bpm over a lot of months. Limb claudication, sinus problems, and bridge of nose cartlidge collapsed in. Horrendous head pressure, dry eye, fungal in mouth and sores, tinnitus and knocking, myopathy, incontinence, cognitive problems short term memory,probably much more that I have forgotten about.. I am in the UK. Where it is called prednisolone. I think steroids should be a black box drug for sure. They can be a very dangerous drug to some. And no professional warned of any of the possible side affects. And when reporting them, I felt gaslighted. So gave up telling them, and tapered myself off..yes it was the only drug used for GCA initially, but no info from rheumatology etc on the toxic side affects. Just left to it! F 68 2 years
60mg 1X day
2/21/2025
 1  Bells palsy Headaches, psychosis , blurrred vision, vision loss, floaters, weight gain, loose skin, joint issues, muscle wasting , Cushing's syndrome, brain fog, dizziness, stomach pain, loose stool, kidney damags Never take this unless the other option is death M 39 10 days
50 1X day
2/20/2025
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 1   Difficulty walking, brain fog, memory, jitters. Dizzy. Will never take again F 74 0 days
1X day
2/18/2025
 1  Sinus infection I took a dose pack for 7 days for a sinus infection. This was almost SIX months ago. I am still currently experiencing high DHEAS levels and it gave me pre-diabetes that still has not gone away. It also gave me high blood pressure that I still have 6 months later. These are not even the tip of it. I still have severe acne, anxiety, panic attacks, tooth pain, headaches, sleep issues, mania, depression, derealization, suicidal thoughts, irritability, and anger. I understand this can be a life saving drug but it needs to be under more serious regulation. The doctor warned me about none of the side effects, and neither did the pharmacist. This drug has ruined my life. I have no idea when this will get better. The doctors ignore me, even though I have clear test results. This should never be given for something like a "possible" tooth infection. I am a full time college student, a mom, and I've had to quit my job and move in with my parents because I can't work due to the panic attacks and other issues it's given me. I'm been given no information by doctors on when it will end or how to get better. All I've been told is that it may go away in "up to a year". I had no previous history of any of these issues before taking this drug. Currently I've changed my diet, hydrate, try to workout, and just trying to make it through this. Everyday is a challenge. It should be illegal to prescribe this drug without prior knowledge of the possibility of living this way with doctors having no idea about the possible effects or how to treat them. I feel so defeated. This is effecting every area of my life. If anyone else has gone through this please feel free to reach out. F 26 7 days
Dose pack 2X day
1/7/2025
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 5  Lungs bronchitis 55 5 days
1X day
10/2/2024
 5  bronchitis and inflamed lungs none started to feel better after a few days - but was also taking azithromycin and a cough medicine called benzonatate M 55 5 days
20 mg 2X day
9/11/2024
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 2  Allergy/hives It has helped stop the hives, but the side effects are detrimental. Anger, anxiety through the roof, shaky tremors in hands, tingling in arms /legs, pins and needles all over, face looking swollen, heart palpitations, just had a panic attack even though it's 8:30pm and i took it this morning, day 2 of 50 mg. I have high blood pressure, osteopenia and anxiety so really not sure this is good for me. F 50 3 days
50 mg 1X day
6/30/2024
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 1  Scleritis I'm no longer taking this medication. I have been off this medication for a year now and STILL suffer from some of the side effects. I never would have taken this medication had I done more research prior to accepting the doctors advice. It's not worth the long lasting affects this medication has given me F 44 6 months
60 1X day
4/25/2024
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Patient History
 4  Herniated Disk This is the 2nd time taking this medicine Both times relieved the symptoms that it was prescribed for. This time I began having a throbbing headache after a couple hours and could not get any relief I am an unmedicated diabetic controlled by diet so I checked my blood sugar it was 485 Each day several hours after taking the medicine the same thing would happen. 14 days of severe pounding headaches blood sugars over 300 and face around eyes feel extremely swollen You cannot stop until you are finished 5 more days I’ll be never here so glad to stop a medicine F 56 14 days
10 1X day
8/12/2023
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 5  Copd Was not able to breathe due to a pulmonary exacerbation with in 2 days felt better no side effects wasn't hungry no pain in other places no headache I think alot of people just like to complain and get attention from family Good product M 74 0 years
40mg 1X day
1/19/2023
 4  Vertigo and allergies Started taking this 2 days ago. Starting to feel better with my vertigo symptoms and some allergy. Having trouble sleeping and stsrted having digestive issues, such as lose stoll. I tend to get loss of appetite when I don't feel good. Hoping the mild issues stay mild and no more accrues F 50 5 days
20mg 1X day
7/14/2022
 5  Autoimmune/Rheumatoid Arthritis Insomnia, weight gain 30 lbs, moon face, elevated blood pressure, elevated sugar, decreased appetite, but the worst was the hot flashes and profuse sweating! Even with the side effects, I haven't been able to stop it. I tried, and after being off it for a month, I was practically bed-bound because of the inflammation in my joints and body. Every joint in my body was hurting. I went back on it so I could function. It's definitely a blessing and a curse. F 47 1 years
10 mg 1X day
6/5/2022
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 1  Help stop vertigo Anxiety, extremely agitated, mood swings, rage, weird pains in eyes, face, and head. Irritable, easily annoyed by everyone and everything, heart racing, mood swings. Do not take this pill unless you don't have another option. I was only on it 2 days. Yes two days!! And all these side effects happen. The heart racing was bad, super anger over nothing. Everything just set me off. The mood swings where awful. Never again. F 31 2 days
20 1X day
5/21/2022
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 1  Bronchitis Rx was the kind you take 6 first day then 5 then 4 etc. After second day taking it I experienced itching in legs and arms. Third day (I stopped that day) extreme weakness all over body, difficulty staying awake, blurry vision, dizziness, heaviness in legs and extreme cold feet (as if I was wearing buckets of ice instead of shoes) After the fourth day and for the next week-week & half my feet continued to feel cold but this time the sole of my feet would turn bluish gray then red & white/yellow, similar to Raynod's syndrome. It started going away little by little and it would come on and off for the next two weeks. Dr agree it was a reaction to the prednisolone. Will never take it again! F 56 3 days
6X day
5/9/2022
 1  Neurosarcoid Blurriness buzzing in head fatigue anxiety depression I had been on prednisolone (UK) for 10 MTHS off now 9 weeks and still have buzzing and hissing in head will this ever go away eventually can someone let me know going out of my mind worrying about it F 62 10 months
30mg -1mg 1X day
4/27/2022
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 1  Covid infection I got bilateral Avascular Necrosis on both femoral head. Fractures and then collapses. my name is Bryan, I live in Alexandria Virginia. I was prescribed prednisone for three months last year as I had back pain from a previous back surgery and then I contracted covid and I was given more prednisone. Two and half months ago I started having pain in my left groin, my doctored thought maybe torn tendon and or labrum tear. After weeks and months of rest I was no better. After X-rays and a final MRI last week, I was informed that I have bilateral AVNs, the head on femoral hip bones have fractured and crumbled. They call this AVN or avascular necrosis, meaning my bone has died. Next week I am having my left hip replaced and then four weeks after my right hip replaced. I am only 40yrs old. The prednisone side effect states possible bone density issues, does not state that the bone dies, that the blood vessels die and then leads to hip replacements. M 40 0 months
30 3X day
4/20/2022
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 2  Sudden Deafness Insomnia, extreme anger and anxiety, became suicidal, hot flashes, increased appetite/cravings, gained 8 lbs, hand tremors, blurry vision, moon face, fat hump on neck, eye pressure, headache, hair loss & texture change, fatigue. After stopping I developed itchy scalp and face, face & chest acne, red, blotchy face. Dr didn't warn me of ANY side effects even though I have a history of major depression and anxiety. I will never take it again. F 65 3 weeks
60 mg 1X day
4/8/2022
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PREDNISONE  (PREDNISONE):  Prednisone is used to treat conditions such as arthritis, blood disorders, breathing problems, severe allergies, skin diseases, cancer, eye problems, and immune system disorders. Prednisone belongs to a class of drugs known as corticosteroids. It decreases your immune system's response to various diseases to reduce symptoms such as swelling and allergic-type reactions.   (Sources: U.S. Centers for Medicare Services, FDA)

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