DOXEPIN HYDROCHLORIDE Reviews (DOXEPIN HYDROCHLORIDE)

Average Rating: 3.1 (252 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
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More on DOXEPIN HYDROCHLORIDE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DOXEPIN HYDROCHCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Severe uticaria/ chronic hives Pretty drowsy in the morning. I take it at about 6 and then try to get 8.5-9 hours sleep, more if possible. When I first started, it was almost impossible for me to get out of bed without 11 or more hours sleep. Very tired all day for the first few weeks and now I'm fine. My dreams are very intense and I remember them fully all day. I crave sugar like a mad woman and have gained a few pounds which I'm sure the lack of exercise has aided in. I had chronic hives for several months until one week they flared up so badly I couldn't leave the house. Itching, swelling of my face, hands and feet, the worst. Steroids did not help, they only made it worse. Benadryl and cold baths appeared to be the only semi relief I could get. Finally went to a dermo and he gave me doxepin, singulair and allegra. Hives went down but not for about a week and a half, and, I think, because I went to an accupuncturist who did the most help. He told me I needed to keep my body temp low, and part of that was to eliminate sugar, booze, and spicy food or exotic spices. My hives are almost gone or I can deal with the small breakouts, and the breakouts only occur when I eat sugar or drink. The doc finally determined that I have exema and an auto immune difficiency brought upon by too much caffeine and toxins in my body. I now still take doxepin at night and have begun UVB light treatments which should allow me to only take allegra every day and go off the doxepin. I highly suggest looking into homeopathic medicine and watching what you eat if you are not finding a solution. No one should have to live with that crazy itching. F 28 30 days
25 1X day
10/13/2010
 1  Sleep Even though I slept I did not like the drugged feeling so I tapered off over another month This drug causes a withdrawal from hell. I have been off a careful taper for 5 months and I can't work and feel insane. Walk and pace all day, extreme anxiety never had before, shaking, jittering, worse insomnia than before taking. I am also having sever, near seizure like jerks. Can't eat, sweating and worst of all I feel insane, just plain crazy. Only thing wrong before Doxepin was I was working shift work at a hospital and had insomnia. Now I have lost my job and my sanity. This is one bad drug when you have to stop....and I had no side effects while on it. M 42 4 months
10 1X day
9/16/2010
 4  Depression weight gain, memory problems, confusion, some vision problems, vivid dreams I tried other anti-depressants, including Lexapro and couldn't tolerate them. I started at 25 mg. of Doxepin and wound up taking 300 mg. within 6 months. I felt great for a while at 150 mg. There was no weight gain at that point. Then I felt myself going in a cycle. One day depressed, the other day fine. So I began increasing the doses, 25 mg. per week. The cycles continued until I started taking 300 Mg. per day. At that point, the depression stopped. Within 3 months, I gained 45 lbs! I work out regularily, doing 4 miles on the treadmill 5 times per week along with other activities. Even with all of that, I haven't lost an ounce! I had 20/20 vision and now I need reading glasses and sometimes my long range vision is blurred. Also, had a photographic memory and now my memory is about average or slighly below average. I also get confused the odd time, such as opening the wrong drawer to get something. I really dislike the vivid dreams. They tend not to be pleasant dreams either. However, remembering what my depression was like and the problems that I had with other medications such as Prozac, Effexor, Paxil, Serzone and Lexapro, (Cipralex), I am sticking with Doxepin. The worst side-effect that I had with some other meds, (especially Paxil and Lexapro) was severe headaches. And I mean severe. Some other anti-depressants that I tried made the depression worse. Bottom line: Taking Doxepin sure beats having depression. M 56 4 years
50 MG. 6X day
8/16/2010
Email
 1  Anxiety Sedation, dry mouth, impotence HUGE ANXIETY INCREASE 5 days after taking only 2 days and I want to crawl out of my skin - so sorry I took this drug M 62 2 days
1X day
8/16/2010
 2  Anxiety and Insomnia A small amout of Weight gain, I still cant stay asleep. I used to wake up about 10- 15 times a night, Now I wake up about 35 times a night. I don't think this works as well as the doctors think it should. F 20 7 days
10 1X day
7/29/2010
 1  Anxiety and Depression and Insomnia I hate this med! And I can not believe my md didn't tell me about the possibility of extreme weight gain! I had gastric bypass about 5 yrs ago and have been 125lbs ever since. I just went to see my regular md due to my horribly bloated and painful abdomen- I LOOK PREGNANT!. I now weigh 146!!!! I am so pissed! And didn't help me sleep either- I would wake up off and on all night long. F 34 3 weeks
100mg 1X day
6/26/2010
Email
 4  FM/CFD/fibromyositis/insomnia Weight gain, dry mouth, & CRAVING SWEETS!!!!!!!!!!!!!!!!!!!!! M 30 3.5 years
50 mg 1X day
5/19/2010
Email
 5  Chronic PN, with Insomnia None I have been able to sleep well with the med. It does seem to work with the pain meds that I take, and has allowed me to get a good nights sleep for the first time in over a year. I have not had any dreams, nightmares or anything of the such. Maybe a little hung over in the AM, hope that resolves with continued usage. M 46 3 days
20mg 1X day
4/21/2010
Email
 5   In the beginning, I did have dry mouth It was a miracle drug for me. I had strong first-time bout of depression and could not sleep. My Dr. used Doxepin 10 MG with ambien for the sleeping issue along with paxil. The Dr. knew how I hated the idea of being dependent on any drug, so once I was able to sleep again, we worked ahead with the aim that I would first reduce ambien to zero and then reduce the amout of doxepin. While I have never been able to go off paxil, I was successful in reducing the doxepin to lower and lower amount 2MG-1MG or less and only when needed (once or twice per month) My own theory on doxepin is that most people do not realize that while you will use higher amount initially, within a few months, you can (and probably need to)back off dosage amount. And over time, if you are consistent, the amount you need will be incredible small. If I were to take 10MG pill now, I would probably sleep for two days! M 55 10 years
5mg 1X O
4/7/2010
 5  Urticaria, photosensitivity Continued drowsiness upon awakening. Cured that by taking it early in the afternoon so I was sleepy by bedtime. No delayed reaction. Sleep aids take about 7 hours to work on me. By then it is time to get up! Great for my dogs' itching/allergies. They were driving me crazy with their scratching. Since it is a combo of histamine 1 and 2 antagonizers, it is a dream come true. The vet never heard of it, so I go to a regular doctor to get a script for the dogs. It also works wonderfully when I need it, which is not often at this point in time. After doing significant research, I discovered that my itching and photo-sensitivity were due to a bladder problem: chronic interstitial cystitis. Odd but true. F 62 18 years
1/26/2010
Email
 4  chronic hives 1 10 mg pill puts me to sleep but I do have some crazy dreams and restlessness during the night. Tolerable if itching stops. Was taking 1 10 mg doxepin and 1 5 mg predisone. Was allowed to increase to 3 pills but never had to. Hives stopped immediately. Am now off prednisone (5 days) and am starting to get a little itching but nothing major. I will wean off doxepin if all goes well in 3 weeks. F 59 3 weeks
1/19/2010
 4  Myalgic Encephalomyelitis bit of weight gain, lot of constipation, only on 10mg. great help with sleep, antihistamine. Suddenly became allergic to it after 15 yrs. Disaster, had to come off suddenly only 3 days ago. No idea what will happen. Anyone come off after so long? any info really appreciated. 10mg for me the only dose I could tolerate, fell asleep an hour later, was great. 48 15 years
1/19/2010
 4  Insomnia &depression I definately do have vivid dreams , but often did before taking this. It certainly made me able to deal with stressful situations without getting overwrought. It has taken away the ability to really laugh and be spontaneous. I laugh less, however, I cry less. Sleep has improved but can be very sluggish in the mornings. I have gained 20 kilos in the 10 years I've been on it. Some due to lack of activity and developing a sweet tooth. So can't blame it completely for that. F 42 10 years
1/12/2010
 5  Sleeplessness No negative side effects experienced Doctor prescribed for sleeplessness - amazing results, sleep comfortably and through the WHOLE night without waking. Much better than any of the new sleep meds I tried. F 55 2 years
1/9/2010
 5  Hives makes me sleepy and have had No weight gain at all I have been suffering from massive hives for almost 9 years, I had been admitted to hospital because throat had swelled shut emergency room doctor recommended Doxepin and Zantac swelling went away within a few hours. I took this once a day for 30 days within two days of stopping Hives were back and ended up back in hospital. I am back on it and look forward to hives being gone F 49 30 days
1/6/2010
 5  sciatica Drowsiness in the morning, but this was cured by taking my Doxepin earlier in the evening. I have sciatica and take 10 mg. of Doxepin every night. This is a wonderful drug that helps me to relax and fall asleep. It helps me sleep deep enough to keep from rolling around all night from my back pain. If I don't take doxepin in the evening, I am up all night walking around. F 51 2 years
1/6/2010
 3  itching, hives, depression Very very strange dreams.. huge appetite at first but controlled it after a while..very drowsy in the morning F 18 30 days
1/2/2010
 3  anxiety, depression, chronic nausea Dry mouth and eyes, fatigue in mornings and early afternoon, increasing constipation. I started on 25mg in evening and increased to 50 mg. This was a mistake. I am going to lower the dosage to 20 mg. I hope this will reduce the side effects. It did relieve anxiety and decrease the nausea, but hasn't shown any depression improvement as yet. M 63 4 weeks
12/19/2009
 3  Depression Weight gain F 49 10 years
12/4/2009
 2  sleeplessness - depression Severe itching and constipation, improved mental attitude but not worth the itchy feeling all over my upper body - even the inside of my ears itch !! The sleeplessness is worse - I feel like I am "wired for sound". I can only sleep 4-5 hours; the insomnia is worse than before. I have just been on this med for 5 days - it DID NOT help me with the insomnia; made it worse - the itching is driving me crazy - which is weird because this med is also prescribed for people with hives and works very well. It has helped with the depression but after reading all the posts (and the info that came with the med), I am discouraged about taking it - maybe a higher dose would benefit me (only taking 50 mg at night). Right now, I am ready to give it up. There HAS to be another drug on the market for me to take. F 58 5 days
11/10/2009

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