DOXEPIN HYDROCHLORIDE Reviews (DOXEPIN HYDROCHLORIDE)

Average Rating: 3.1 (252 Ratings)

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on DOXEPIN HYDROCHLORIDE: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR DOXEPIN HYDROCHCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Migraine Preventative/Insomnia Doxepin and I did not mix well at all. I was taking it as a migraine preventative with a side effect of "better sleep". Total bull crap. While it has helped my migraines, the weight gain, sweets craving, horrible nightmares, and dry mouth outweigh the benefits for me. The nightmares are so bad. In the last 6 months, I have awakened my husband probably 20 times thinking that whatever I was dreaming about was real and I was deathly afraid. I stopped taking Doxepin 3 days ago, and while I've not felt any withdrawal symptoms, I am still having terrible nightmares. I have lost about 2 pounds in those 3 days though. The day after I stopped Doxepin, I had 0 cravings (Thank goodness). Another problem I'm having with my discontinued use is severe insomnia. I've slept 3.5 hours in the last 2 nights. I'd kill for a night of rest. :( F 25 3 months
50 mg
6/28/2012
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 1  Insomnia I've been on it for 3 days and I've gained 5 lbs!! I feel "hung over" & only sleep 2 hours. Dry mouth, weird dreams,etc... The weight gain is the worst. No change in my eating habits. It was fast! The side effects are horrible!! F 39 3 days
50mg
5/12/2012
 3  I am taking it to stablize me Dry mouth,vivid crazy nightmares,sleepyness,droggy I like it alot it helps me with my depression and gets me thru the nite helping me sleep but i could live without the vivid dreams. F 24 3 months
50 mf 1X day
4/26/2012
 5  Bad hives BAD weight gain, tired in the morning, crave sweets, dry mouth, and I believe some memory loss...can't remember! Six doctors searched for a year to find out why I had horrible hives all the time. It was given to me as "just try it"... and it worked! I have zero flare ups when I am on it, but as soon as I don't take it...the hives are back! I have put on 50 - 60 pounds over the past 4 years and would love to try somethig else that works just as good. I hate being fat...but the hives were worse. I have to take it every night an hour before I go to bed and I will sleep ALL night...but if I try to get of off it, I can't sleep at all. M 43 4 years
50 MG 1X day
4/11/2012
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 1  Insomnia Took in the form of 6 mg tablets of Silenor along with Rozerem. Did not work at all. Did not sleep. Am wide awake today. Ended up taking 2 more 6 mg after several hours because it looked safe since Silenor is such a low dose of the Doxepin HCL. Not worth it at all! Did not work last night (slept maybe 3-4 hours fitfully) from around 4 am and was wide awake at 7 am, no drowsiness the next day! No weird reactions, crap just did nothing! Ended up taking 18 mg of Silenor for 1st time (just got samples); 8 mg of Rozerem (did not work either), 2 doses of Benadryl (more than 4 hours apart), Ibuprofen, 9 mg of Melatonin and 1 mg of Klonopin, and still no sleeop! Even took Guanfacine (3 mg) for Adult ADHD (also have depression, panic attacks, general anxiety, along with insomnia, trouble staying asleep, and the ADHD (Guafacine had a sedative effect for about 3 nights, but still take for the ADHD. Silenor sucks, too! Have also tried Trazedone, Restoril, Seroquel, Mirtazapine, other trycyclics, Lunesta, and Ambien. Beginning to think Benadryl and Melatonin work better! Am ready to try a barbituate-based sleep medicine if my Dr. will give me a few for a few nights of sleep! Only slept 2 out of the last 8 nights, constantly woke up but was at least able to get back to sleep those 2 nights. Usually cannot fall asleeo or wake up after 1 1/2 -2 hours and stay awake. IAt least this worthless medicine was given via samples! Ambien never worked great, Lunesta never worked great (and lleft a bad taste), Trazedone and Restoril were like taking nothing, Seroquel made me feel sub-human, Mirtazapine (?) made me stutter terrible and feel like crap. Trycyclics make me fat and I have to take large doses for sleep. I am so tired of this! F 42 1 days
18 mg 1X day
3/31/2012
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 3  Itch relief I really didnt expierience side effects M 14 2 months
10 mg
3/26/2012
 1  migrane preventative Worst drug EVER noticeable hair loss and weight gain eye pain and restless legs and arms and Maybe 4 hrs of sleep per night if I'm lucky and I still have migranes ;( F 39 3 months
50mg
3/14/2012
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 1  Horrible itching For three days it seemed great. This is the 4th night; itching worst ever. Unable to sleep This seems to be a dangerous drug. I'm not taking any more and will depend instead on acupunture and healing hands. F 84 4 days
10 1X day
2/26/2012
 4  for sleep For the 1st time takin dox i took 2 and i was out ,but i was up at like 3;30am i went to sleep at 7 pm i did fall asleep again ,but i was alil googally in the mornin. M 57 1 days
75mg
1/11/2012
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 3  Insomnia weight gain I tried taking the 3 mg. compounded version, as my insurance wouldn't pay for the Silenor because it's so expensive. The 3 mg. didn't help. So, I tried emptying out part of a 10 mg. capsule to approximate around 6 mg., which helped but still didn't get me 7-8 hrs. of sleep per night. For the past two or three months I've been taking the 10 mg. per night, which at first made me groggy upon waking, but now just allows me to stay asleep all night or if I do wake up, I'm able to go back to sleep right away and I feel great the next morning. However, I've gained 10-15 lbs. in this period of time, without changing my eating habits. I don't really feel hungrier than I did before, nor do I feel that I consume more than I did. However, the weight gain is piling on and I can't keep it up. So, I'm going to try to reduce the dosage to 6 mg. and then 3 mg. to see if I can get some sleep and lose some weight. The weight gain and mild constipation are the only side effects I've had but the weight gain is enough for me to try to get off of it. F 56 5 months
10 mg. 1X day
1/4/2012
 5  Insomnia I was tired for the first 2 days, but now wake up feeling pretty good. This is a wonder drug for me. For years I have been waking up around 2:00 A.M., and lay awake for up to 2 hours. I would be tired all day, and fall asleep in the evening. Now, I sleep through the night. If I wake up, I can roll over and get right back to sleep. I dream every night, which I have never done. No nightmares. I get 7-8 hours most nights, and often sleep through my wife's alarm, which used to wake me up easily. Great stuff - wish I had discovered this years ago. M 51 3 months
50 mg 1X day
12/29/2011
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 1  Insomnia Instead of keeping me asleep, it made me wake up 20 times more frequently! Felt very sedated all the next day, and tired, due to not sleeping! Morton Grove Doxepin Elixir (Liquid) this generic brand was not effective for sleep for more, in fact it made me wake up about 20 times a night. I kept waking up and falling asleep and waking up. Bad.Anyone have better luck with different drug manufacturer? Different generics do act differently for me. I was only taking 3 milligrams, tiny dose, sometimes less. Doxepin is a potent Antihistamine! F 39 30 days
3 mg 1X day
12/27/2011
 4  Migraines I have a hard time getting out of bed. I am having some anger mood swings once and a while with out reasons for them. Always craving sweets. I am on 200mg a day to control my sever migraines. It has helped a great deal. I take 1 in the morning and 3 at night as prescribed by my doctor. I am always very tired but have migraines maybe once every few days. F 20 1 months
50 4X day
12/23/2011
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 4  Severe uticaria/ chronic hives Getting out of bed in the morning was like waking from death. About a month into the therapy started packing on the pounds. Dry mouth. I would recommend the Doxepin for anyone, like me, who gets severe, entire body swells to the point of bruising, hives. Doctors tried everything: OTC antihistamines, prescription antihistamines, anything with both H1 and H2 blockers. I tried acupuncture, oatmeal baths, herbals, anything - I'd run through fire if I thought that would help. Until Doxepin the ONLY thing that worked was Prednisone with all its dire warnings and an occasional Epi shot. So I loved the Doxepin - until I started to get FAT. I have been offf the Dox for a month now and still - clothes don't fit. Have really adjusted my diet and lifestyle. Can anyone tell me when the cravings and weight gain will please just go away? F 48 120 days
25 mg 1X day
12/19/2011
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 1  was not sleeping during the night I was having severe night sweats, swelling of my hands and ankles and dry mouth so bad that my tongue literally felt stuck to the roof of my mouth. I felt extremely sluggish the next day up until about noon then it gradually wore off. Also had strong heart palpitations which made me feel that I was having a stroke because my arms and legs felt very heavy in the morning and it was hard for me to get around. What kind of doctor would even consider putting their patient on this medication? Obviously my doctor did not know me well enough- after spending over an hour explaining just how sensitive that I am in taking medicine. I have reactions to medications that most people do not but one thing I do know is that Doxepin is definitely not for me and I will not take it ever again!! If you want to feel miserable and have cravings for sweet things all the time and have dry mouth so bad that your tongue literally sticks to the roof of your mouth and the next morning you wake up feeling very sluggish and really do not come out of this fog until about noon. This is a very serious drug that can harm alot of people especially people like me who are extremely sensitive to medications. F 52 2 months
75 mg 1X day
12/7/2011
 1  Insomnia Taste perversion, drymouth and throat, painful in mornings. When I began taking this it worked well for falling asleep, but had to have about 10 hours to sleep or would wake groggy. By third day, I was awakening with very dry mouth and throat that made the tongue, gums, and throat burn. Taste of EVERYTHING is terrible. Stopped taking after third day, and dry mouth has pretty much gone away, but the taste perversion is still terrible... hoping it will go away. M 47 3 days
100 MG 1X day
11/23/2011
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 3  Depression, Sleep, Weight Gain It caused sleepiness, but more than 50 mg. daily caused an asthma attack. I'm assuming that this is due to the antihistamine in it. It also caused Cervical Dystonia (a neurological condition of the neck) as well as impeded urine flow. Additionally, it made me groggy the next day and sometimes weak. I did gain some weight (which I desperately needed to) from this drug and it did help me sleep. You just have to be careful about not taking too much of it, especially if you have asthma or another breathing problem. M 49 4 years
25 MG 1X day
10/25/2011
 4  For vertigo. When I tried to get off of it I felt like I was coming unglued. No energy, felt confused and to mention the weight gain, all I want is sweets breakfast, lunch, and dinner. This was prescribed for me by a neurologist. It really helped my vertigo. I sleep very well and all night if I don't eat desserts late in the evening. Another thing I like about doxepin it makes me very energetic. It has its pros and cons, but as for me, I'm better on it. F 51 4 years
75MG 1X day
9/24/2011
 1  Insomnia This drug is toxic. This is not good medicine for itching (similarly to atarax)! Itching can be due to liver damage: doxepin is antidepressant and it makes liver damage worse. Use regular antihistamines for itching. Be very careful with withdrawal. It can kill you. serotonin 5-HT2A receptor. M 30
1X day
9/11/2011
 5  depression, anxiety, insomnia I've been on a low dose for several years. This drug helps me a lot with irritability and insomnia..however the withdrawal from this med is a monster. It's a bit like having a migraine without the pain after several days off the drug. Extreme irritability can also be an issue when abruptly discontinuing the drug. Biggest issue is that even the lowest dose leaves me groggy and I can only take it when I have a regular sleep schedule. Effective drug but should only be taken if the side effects can be tolerated and for those who have a stable schedule. F 40 2 years
5 mg 1X day
9/2/2011
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