Reviews for CYMBALTA26 ratings: (side effects include serotonin syndrome)Edit Filter | Clear FilterCompare CYMBALTA with similar:
Type: Rx Drug
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Results are sorted by Date added. Key to Ratings: 1=LOW (I would not recommend taking this medicine.) Page: 1 2 |
More on CYMBALTA: Reviews Summary | Drug Safety Information
| RATING | REASON | SIDE EFFECTS FOR CYMBALTA | COMMENTS | SEX | AGE | DURATION/ DOSAGE | DATE ADDED |
| 1 | MDD & GAD | - new onset of EXTREME restless leg syndrome (like my body starts flailing around uncontrollably) - anger, irritability - aching legs - chills - unable to sleep or even relax at all due to RLS (which I didn't even know was a thing until I got it from duloxetine) | Wondering now if I am doomed to have RLS for life?? This sucks. Didn't help my depression and I still have the RLS 1.5 weeks after quitting duloxetine. | F | 40 | 3 weeks 30mg 1X day | 1/15/2023 | 1 | Depression | Serotonin syndrome, what I called the "zippy zappies," the arm and brain tingles | This took around 6 months after completely stopping (after tapering down) taking this medication. Its beneficial effects were short lived and its side effects lasted the whole time, but the worst thing was stopping taking it, i felt absolutely awful for months, which is not something that a depressive person like me should have to deal with on top of my illness. | F | 47 | 2 years 1X day | 6/2/2019 | 1 | Bipolar | Intense GI issues, Chronic severe abdominal pain,chronic severe skin thinning, acute unexplained bruises, chronic severe bruxism, chronic nightmares,acute migraines, chronic pain in joints/muscles I've never had before, Severe cognitive decline, severe serotonin syndrome, chronic heart issues, chronic blood pressure issues, chronic severe suicidal ideation, chronic disorientation, chronic vertigo, chronic severe dehydration, chronic dental destruction, chronic severe fatigue, chronic severe insomnia, chronic severe raging, chronic severe depression, chronic severe anxiety, chronic severe PTSD, chronic severe borderline personality disorder, chronic severe bipolar disorder, chronic severe apathy, chronic severe despondency, chronic balance issues, chronic exacerbation of IBS-C, exacerbation of OAB, tremendous difficulty urinating, tremendous difficulty voiding, cannot void regularly naturally, blood in stool, chronic bleeder, chronic nausea, chronic fever, chronic paranoia, decreased vi | PURE POISON!!! I'm suffering severe life-threatening side effects also suffered severe withdrawal effects when taken off cold turkey. VERY allergic, VERY addicted (only ever taken as prescribed). It is killing me; I can feel my body shutting down; slowly but surely. Just a matter of time. I have zero life quality, zero life purpose, 85-90% homebound, can't do basic self-care, can't do 99% personal business, and on and on and on. | F | 54 | 1 years 30 mg 1X day | 6/14/2018 | 5 | Fibromyalgia | I had to stop using it because I was diagnosed with Bipolar and was taking to other medications that had Serotonin in them causing be Serotonin Storm. It was fine before taking two other medications with Serotonin in them. | Cymbalta worked great for Fibromyalgia. It was nice to be able to swim again because my skin wasn't sensitive to the cold. I was disappointed when I had to quit taking it. But I had to make a choice which was worse the Bipolar or Fibromyalgia. | F | 54 | 4 years 3 mg 1X day | 11/10/2017 | 1 | Migraine | Worked fairly well till I got serotonin syndrome. Went from 60mg to 30mg then every other day. Withdrawal is hell. Sweating, anxiety, overall pain, shaking, can't function. This already for 3 weeks. | I hate it! Doctors needs to warn you about withdrawal also. | F | 52 | 4 months 60mg | 2/16/2017 | 1 | Fibromyalgia | Moderate Serotonin Syndrome with extremely dilated pupils. Took 28 hours for the extended release capsule to get out of my system and it was hell. Anxiety, rapid pulse, nervousness, shivers, cold sweats, panic attacks, seizures (non-convulsive), nerves felt like they were on fire, dizziness, shakiness, and difficulty breathing. | Within the first four hours of taking this medication I had issues. If you are sensitive to serotonin DO NOT TAKE. | F | 27 | 1 days 30 MG 1X day | 8/10/2015 | 1 | depression/anxiety/adhd | emotionless, sleeping 14+ hours per day, worsening anxiety, inability to focus, zero sex drive, extreme fatigue, low blood pressure, seratonin syndrome. interacted with visine which irritated/burned my face. had an extreme reaction the second week of use. Spent the night in bed, low temp (6 degrees below normal), confusion, tremors, shaking, extreme paranoia, anxiety. | DO NOT TAKE THIS. it almost killed me, and worsened ALL of my symptoms including giving me new problems. | F | 24 | 21 days 30mg, 60mg 1X day | 7/20/2015 | 1 | Anxiety | Side affects: Tingling in hands and feet, brain zaps, dizziness, insomnia, paranoia, confusion, disorientation, depersonalization, tongue necrosis, early dementia, hair loss, skin boils, Crying spells, depression, worsening of anxiety, rage, dehydration, appetite loss, but weight gain, mood swings, nausea, fatigue, restless leg syndrome, etc. etc. etc. YES IM SERIOUS!!! THIS DRUG IS EVIL and has stolen 2 years of my life... because the side affects slowly creep up on you. I honestly thought I had multiple sclerosis and contributed a lot of my symptoms to other things. PLEASE LISTEN when I tell you to RUN... Not walk away from this drug!!! Shame shame shame on you Eli Lilly! | CYMBALTA WILL KILL YOU!!!!!!!!!!! And for anybody who says they don't have side affects, or give this drug a highly satisfied rating, you just haven't taken it long enough!!! Careful when stopping this drug as the withdrawal is gruesome!!!!! | F | 32 | 1 years 30 | 2/23/2015 | 2 | Depression | Worked great at first but now I'm always exhausted, have a horrible non-stop ringing in my ears, feel like I have uncontrolled anger often, suicidal thoughts, feel like I'm going to explode & my restless leg syndrome is only increasing. | Going to taper off, hopefully with success! | F | 51 | 6 years 60 1X day | 3/2/2014 | 1 | serotonin syndrome | My blood pressure went up to 165, I could not breath and I could not see clearly. Horrible drug. I do not understand why doctor gave me this poison after diagnosing me with high serotonin. Cymbalta raised serotonin even more. | Stay away from this drug, it can kill you. | M | 52 | 1 days 30 1X day | 1/3/2013 | 1 | Depression and anxiety | Almost died. Eli Lilly told doctor that I could drop dead at any moment. I had no history of heart trouble. Taking 100mg. Serotonin toxicity? Took 4 months to come off it. List of side effects during withdrawal is lengthy. Extremely unpleasant and at times frightening. Too many to put down here. A couple of side effects have no yet disappeared even after stopping Cymbalta over 4 months ago. | My personality changed while I was on Cymbalta but has returned to 'normal'. Now I am embarrased over some earlier behaviour. Also my brain has cleared (not confused as it was when doctor was warned of likely imminent death) and my memory vastly improved. I am amazed that I seem to have escaped. However, at night I am usually sweating around neck and down chest despite the fact that it has been winter. I find that I can't control my environment to ensure that I am neither too hot nor too cold. There seems to be virtually no margin, no comfort zone. I will either be too hot or almost immediately feeling chilly no matter what I do. I do not have a temperature. My husband can be wearing a coat and beanie while I am in a sleveless cotton nightdress and have the window open. It is not menopausal. That was over about 10 years ago with no side effects (no hot flushes etc.) | F | 62 | 500 days 1X day | 9/9/2012 | 1 | fibromyalgia/depression | extreme restless leg syndrome, involuntary arm and leg movements, difficulty breathing, vertigo, "spaciness" | it was almost as if i were allergic to it | F | 52 | 5 days 30MG 1X day | 2/10/2012 | 1 | for pain | i have chronic fatigue syndrome and i think i have fibro. having a lot of muscle pain. took cymbalta at 10:30 am. it's now 5 pm and i'm extremely, nauseas, tired, irritable and running to the bathroom. i will not take it again. | M | 70 | 1 days 1X day | 10/29/2011 | 1 | severe anxiety,TN,Migraine,Back | severe fatigue, Restless Leg Syndrome, no motivation, wanting to sleep all night and day, no relief from migraines...made them worse. dry mouth, no sex drive, insomnia when trying to lay down, severe bruising without bumping into things, eye pains | it may have helped with my anxiety but the side effects are not worth it at all. I would never reccommend this drug to anyone. I have decided to come off of it today but i hear the withdrawl is horrible and im actually scared | F | 27 | 3 months 60mg 1X day | 10/10/2011 | 4 | GAD | Exacerbation of restless leg syndrome, night sweats, vivid sometimes disturbing dreams, increased urination and thirst, some libido reduction (fixed by manipulating dose), possible gastrointestinal issues | I started taking cymbalta when I realized my anxiety had no basis in reality, I was anxious regardless of whether I was worried about something specific or not. At that time I was severely underweight as I could eat only a few foods in small quantities without becoming nauseous and vomitting. In the first year I gained thirty pounds. In the second and third years I have gained and lost and gained about ten more pounds, my weight fluctuates with my level of physical activity. I feel that my weight is much more reasonable now as I have a bmi of 26 instead of 18. Restless legs syndrome runs in my family and I had had it very mildly before taking cymbalta. At about 2.5 years into taking cymbalta the restless legs became unbearable, I now also take mirapex for the restless legs. In the beginning I was taking 60 mg per day and my sex drive dropped to zero. I subsequently started taking 30 one day and 60 the next a d this has brought my sex drive back to normal. I have regular GI issues which my doctor thinks may be a result of dairy or gluten allergy tho I think it is a side effect of cymbalta. I have also experienced a distinct urgency and increased frequency with urination. Once before I realized how serious it was I actually peed in my pants on the way to a bathroom. I haven't peed in my pants since I was five years old so this was really shocking. I literally could not stop the flow but I had peed only an hour or so before. I also have very vivid dreams that are either fantasti | F | 25 | 3 years 30mg/60mg 1X day | 1/10/2011 | 2 | CFIDS/Fibromyalgia | Chills, sweating without fever. Severe worsening fatigue than I experience with Chronic Fatigue Syndrome. Feel like I can barely move about. Zombie-like feeling with a crawly feeling on my skin. In just 3 doses I have had a huge reduction in pain BUT it is not worth the distress for me to take another pill. | I was hoping for pain control and a boost in my energy as I have read that it can help with both. Since developing Chronic Fatigue it has been frustrating looking for something that can help me regain my level of functioning. Perhaps there is no magic bullet. | F | 60 | 3 days | 8/22/2009 | 3 | Fibromyalgia, radicular pain, HA's | 30-40 lb wt. gain, initial vivid nightmares, extreme constant thirst, dizziness, flat affect, complete loss of sex drive, continuing migraines- post concussion syndrome ha's unrelieved, dizziness, brain "zaps", and probably more that I've not yet even realized. | I started Cymbalta after being on numerous antidepressants for Post concussive migraines, as well as leg pain from low back problems & post-op lumbar surgery. I would very much appreciate anyone who would like to discuss via email of this drug- or many others I've also had severe reactions to! (I need to find a support system) as I'm an RN, and been through a lot as I see many others as well have. Forgot to refill and had horrible withdrawel- flu-like, vomiting, vertigo etc. lasting for days. Got back on the med and leg pain greatly relieved. 40 lbs. later and I've decided to stop the med. I've always been a bigger person, now I'm obese and on BP meds as well. Trying to slowly become drug-free, very hard! Hoping being off of Cymbalta will help greatly! | F | 44 | 1 days | 1/24/2009 | 3 | Dysthymia | Wellbutrin XL stopped working for me after 6 years. Cymbalta was the 2nd antidepressant my doctor had me try, after Celexa failed to help. On 60 mg Cymbalta daily, I had some nausea at first which went away after a few days. I also had a day or two of mild, somewhat interesting visual alterations, particularly at night; sometimes, lit objects would go dim as I looked at them. This visual weirdness went away after 48 hours. Cymbalta caused extremely dry mouth which lingered throughout the trial course. Cymbalta altered my orgasms; climax took much longer and was less intense. The worst side effect was severe restless leg syndrome which disrupted my already crummy sleep. I had some samples of Requip and Mirapex I received from my sleep doctor, which did help the RLS. However, my psychiatrist did not think it wise to add another drug to treat a side effect of this drug, and took me off Cymbalta. | My dysthymia manifests as apathy, cynicism, lack of motivation, head-to-toe body, joint and muscle aches, dyspepsia/IBS, overeating, physical and mental fatigue, word retrieval difficulty, 'brain fog', insomnia, and a generally unsociable, 'bah humbug/grumpy old hag' attitude. 60 mg Cymbalta daily helped my IBS a lot and modestly improved my mood, attitude and motivation. Cymbalta reduced my aches and pains by about 50-60% (Celexa actually worked better with a 90% reduction in pain). Cymbalta did not worsen my insomnia and may have even helped a bit. I was able to enjoy a cocktail or glass of wine in the evening without problems. Unfortunately the negative side effects outweighed the benefits. I was able to stop Cymbalta cold turkey with no problems, but I also immediately started taking Pristiq and I've remained on Wellbutrin XL, which may have minimized any withdrawal symptoms. | F | 46 | 4 weeks | 1/17/2009 | 1 | depression | confused mental state,inability to organize thoughts,helpless frightening emotional state,seratonin syndrome like condition,terrible dreams | side effects occured quickly after starting 30mg time release capsules, capsules very hard to taper off,I don't recommend it to anyone my mental state before Cymbalta was normal, a little depressed,never had these expierences with Zoloft. | F | 59 | 3 weeks | 12/20/2008 | 1 | Depression-Chronic Pain | Horrible migraine, and worst physical pain of my life. Could barely move a muscle (all of which were ridgid) after just one dose of 30 mg. All because my doctor did not read the prescribing information! Do NOT take this drug if you are using Ultram/Tramadol, St. John's Wort, HTP-5 or ANY Serotonin altering drug or 'natural' suppliment. You will get a Serotonin Syndrome. | This was first given to me while I was inpaitent, even though I was on a high dose of Tramdol AND also taking an OTC suppliment called HTP...Read about Serotonin Syndrome, it can be fatal. It is scary to think doctors do NOT always do their homework or really look at a paitents meds! (I am on 13 because I have an autoimmune disease). Cymbalta is bad news! Stay away if you can or at least research it very thoroughly before putting it in your mouth. | F | 44 | 1 days | 12/20/2008 |
CYMBALTA (DULOXETINE): Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain). Duloxetine may improve your mood, sleep, appetite, and energy level, and decrease nervousness. It can also decrease pain due to certain medical conditions. Duloxetine is known as a serotonin-norepinephrine reuptake inhibitor (SNRI). This medication works by helping to restore the balance of certain natural substances (serotonin and norepinephrine) in the brain. FDA Approval Date: 2004-08-03 (Sources: U.S. Centers for Medicare Services, FDA)