GLUCOPHAGE XR Reviews (METFORMIN HYDROCHLORIDE)

Average Rating: 3.4 (56 Ratings)

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GLUCOPHAGE XR  (METFORMIN HYDROCHLORIDE):  Metformin is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Metformin works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.   FDA Approval Date: 2003-04-11 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on GLUCOPHAGE XR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR GLUCOPHAGE XRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Type 2 Diabetes Flatulence and possible hair thinning. Diarrhea symptoms disappeared after a few days of using the drug. My A1C is now at 5.7. I can eat whatever I like and it doesn't seem to raise my A1C. Glucophage XR is a miracle worker. M 41 1 years
1000 2X day
10/13/2011
 4  Type II Diabetes None that I'm certain of, but it may be causing GERD or agravating an existing condition. Very inexpensive at WalMart and keeps me in the 120 range on my meter M 64 3 years
500mg 1X day
1/15/2011
 4  Type II Diabetes Slightly softer stools. I truly wonder if most of the commenters here are writing about the correct drug.

Regular glucophage causes diarrhea in many people, but Glucophage XR (extended release) usually doesn't. Once I was taken off regular glucophage and onto XR I could leave the house with confidence again! :-)

You may have to haggle with your insurance company (which will want to put you on a "generic glucophage" which isn't time-released) but if regular glucophage gives you "the trots" your doc can write the script as "medically necessary". This is what I had to do to stay on this drug which works quite well. Over the years I have had to add 45 mgs of Actos 1/day, and Byetta, but I am doing very well, feel good, and have good glucose control - and I am not overweight.

F 50 14 years
1000 mgs 2X day
10/12/2010
 2  polycystic ovarian syndrome horrible diarrhea every other day or so, stomach PAIN, light headedness, dislike for favorite foods, strange cravings, shakiness, extreme hunger pangs, very bad gas I am 5'5" and 125 pounds...I don't need to lose weight and I don't have diabetes. But I do have terrible PCOS and endo. My period is more regular, but I don't think it's worth it. I couldn't tolerate the regular metformin, so my RE switched me to this. After 45 days, still terrible! Does it get better? I'm about to call it quits on this med. I am sick of being sick. F 35 45 days
750mg 2X day
6/3/2010
Email
 2  PCOS Loss of appetite, throwing up The side effects went away when I switched to the non XR F 29 4 years
7/16/2009
Email
 5  PLOYSTIC OVARY SYNDROME FLUSHING F 16 1 days
6/16/2009
 2   Bloating, Constipation, hair loss, fatigue with an increase in dose these symptoms increased in severity F 35
2/19/2009
 4  PCOS My hot flashes and acne on my back vanished instantly. I had cramping because it made me ovulate again. I went off it because other things are happening in my body but I am actually looking forward to getting off it. It brought my sugar down 20 points and I am no longer prediabetic. M 43 3 months
12/15/2008
 4  PCOS and Metabolic Syndrome has kept my glucose levels in check. hasn't really reduced hair growth or helped me lose weight. F 45 4 years
12/14/2008
 4  PCOS/ Pre-diabetes This has been much better than the regular metformin. I take one 500mg at night. Once in a while I may experience stomach pain, but usually not. I have to be careful about dairy products when I take this med. I have not been real consistent with taking the pill, but when I am, it regulates my period. I have not had hair loss, or bad digestive problems. I may have lost some weight, but I do not take this every day like I should. I am going to start back on this and take it daily (nightly actually). It does help regulate my periods and glucose levels. F 40 1 years
12/6/2008
 1  diabetes hair loss, gi problems, weight gain did not lower blood sugars, had hair loss in patches, did not know which way my bowel would go, after 2 years quit working, up from 1000mg-to 2000mg- to 3000mg to 4000mg in 4 years time F 58 4 years
11/23/2008
 4   Had stomach pains and gas build up causing those pains at times and still do Lost and kept off over 40 lbs; first 30 came off within two months of starting the meds. F 24 10 years
6/23/2008
 3  Diabetes 2 First took Glucophage and experienced HORRIBLE stomach cramps, to the point of almost passing out at times. Changed to Glucophage XR and experienced no more stomach cramps. Has helped with the blood sugar levels. F 57 10 years
5/9/2008
 5  Diabetes Diarhea I have been able to determine that the diarhea is directly related to eating too much fat in the diet - cut the fat intake and the diarhea is gone. F 62 7 years
3/17/2008
 4  Diabetes Type II Horrid gas and periodic GI upset. Worked well at maintaining BS control. F 52 4 years
2/27/2008
 1  blood sugar regulation I thought I had the flu F 65
2/20/2008
 4  high blood sugar diarrhea for first couple of weeks, mild nausea after 5 days of taking 500 mg/day I felt better than I had in years! F 48 6 weeks
11/17/2007
 4  PCOS recurrent GI issues- IBS?? +return of menstural cycle!!+ have not lost weight Much better tolerated than regular glucophage. Currently take 1500mg before bed. Sometimes wake up with upset stomach, but subsides after breakfast. Hoping to loose weight...but not yet. After 8 months at this dosage have approx. a 45 day cycle. F 28 3 years
9/15/2007
 4  PCOS The first two weeks I had some stomach cramping and a lot of pooping (not drastic). Now that I've been on the medication for a few months, I have noticed that I don't poop for about two days with uncomfortable bloating. I have been taking Metformin XR for approximately two months for PCOS. I take 500 mg in the morning with breastfast and 500 mg in the evening with dinner. I noticed within a few days of starting this medication that the visable swelling and discomfort in my legs (cankles) had decreased significantly. I have not lost any weight with this medication as of yet, but will talk with my Endo regarding possibly increasing my dosage. FYI: I also take Synthroid 100mg (hypothyroidism), Orthro Tri-Cyclen Lo (PCOS & bc), Effexor XR 75 mg (anxiety/depression), and Spironolactone 50 mg - one in morning and one in evening (PCOS). I have heard that taking the Spironolactone with Metformin XR had good results with PCOS patients. I will update everyone in a few months :) good luck and be patient! F 28 2 months
6/29/2007
 5  PCOS I started taking Generic/MetFormin first 2 Months - remember having stomach discomfort - I requested Brand from Doc who gave me Rx for Extended Release - its Great. I started out at 500mg and now 6 months later taking 2000mg - I have lost 20 lbs - however I do exercise - lightly, cut down on my sugar and carb intake and lowered my total caloric intake. 20 lbs in 6 mos is not alot - but I feel better and eating better - I also noticed my bodys water weight is less - I am less swollen all over - holding less water eventhought I am drinking more than enough every day. Hope my post helps. I am currently under docs care for In Vitro - Doc told me to stay on this Medication so I will do. I do get bloating and mild stomach discomfort - I just drink water and poop then I feel so much better - however, I do have IBS so its understandable how I differ from the rest of the comments out here - having IBS w/constipation - this Glucophage really helps me all over. Great Medication for me with few irritations. F 35 6 months
5/11/2007

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