PAXIL CR Reviews (PAROXETINE HYDROCHLORIDE)

Average Rating: 3.3 (595 Ratings)

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 ANTIDEPRESSANTS

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PAXIL CR  (PAROXETINE HYDROCHLORIDE):  Paroxetine is used to treat depression, panic attacks, anxiety disorders, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder). It works by helping to restore the balance of a certain natural substance (serotonin) in the brain. Paroxetine is known as a selective serotonin reuptake inhibitor (SSRI). This medication may improve your mood, sleep, appetite, and energy level and may help restore your interest in daily living. It may decrease fear, anxiety, unwanted thoughts, and the number of panic attacks. Paroxetine may lessen premenstrual symptoms such as irritability, increased appetite, and depression.   FDA Approval Date: 2000-12-06 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on PAXIL CR: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR PAXIL CRCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Depression and Anxiety Increased appetite, cannot achieve orgasm, yawning, very sleepy and weight gain! I started on 12.5 then went up to 25mg and 3 weeks ago started on 37.5...I have not been able to cope well with a specific circumstance in my life and have had to go on a higher dose recently, I also believe that my body has become immuned to the previous dose....starting to feel much better, am very tired and sort of numb but I'd rather have that than the severe depression, crying and anxiety I was having!! Paxil has been a lifesaver for me and my family! F 49 6 years
25/37.5 1X day
8/22/2013
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 5  Horrible anxiety and depression weight gain and carb cravings. very tired and anorgasmic when on 25 mgs. but not when on 12.5 mgs. Paxil has saved my life several times over past 12 years. I have been on and off of it depending on stressful situations in my life. It does cause major weight gain but it is the only med that helps me with major anxiety. Helps a lot with IBS also. A great drug for me!! F 50 12 years
12.5/25 mg 1X day
7/29/2013
 3  Anxiety Whilst my business/work stress induced anxiety has been completely cured, the impact on my sex life is worrying... The other night my wife and i decided to have a quicky in the back of our car, however the quicky turned out to be a marathon session becaused i was quite simply unable to achieve and orgasm! Very frustrating! We thought nothing of it as we had been drinking, but a few nights later the same problem struck again and after 30mins of pounding away at my poor wife, she said enought of that, rolled me onto my back and had to jerk & suck me off for another 15 mins before i could eventually cum. Whilst all men want to feel like a stallion - this is a bit rediculous! Any advice would be greatly appreciated! M 33 15 days
25mg 1X day
5/9/2013
 1  anti-social extreme weight gain F 37 365 days
20mg 1X day
11/17/2012
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 3  Anxiety/Panic attacks Major weight gain!!! About 45 lbs in a year!!! Also very tired, very sleepy ALL the time...very hungry all the time but even not over indulging or giving in, the weight piled on. I worked out, ate right..and it did not matter!!! It did help my anxiety but the weight gain was not worth it. I switched to Prozac. F 30 12 months
20mg 1X day
11/2/2012
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 4  Depression Nausea, drowsiness, no crying, numbness, eye twitching, 30 lb. weight gain I was initially taking 12.5 mg/day for 9 months. For the first 4 months, I was diligent with exercising and good eating habits and actually lost weight. During the 5th month, I was injured and the exercising had to stop. Interestingly enough, I sunk back into depression and had to double the dosage by the 9th month. When I stopped exercising, I also started to gain weight almost instantly (20 lbs. in 5 months and then 10 more in 2 months after doubling the dosage). I have been exercising again for the past 2 months and haven't lost a pound!!!! However, on the double dosage, I am back to myself again. Much happier, in control, less anxiety, sociable, not obsessing about things. Not sure what to do. Might see my doctor about going back down to 12.5 mg and continuing the exercising. F 42 1 years
12.5/25 mg 1X day
10/9/2012
 5  Depression/Anxiety/Panic Disorder Why are any of you taking regular Paxil? The drug has been reformulated as Paxil CR (constant release). The new formulation takes away most if not all of the side effects as the problem with regular Paxil was its short half-life (4 hours). Doctors should NOT be prescribing regular Paxil anymore. Paxil CR is an entirely different drug. Only use BRAND NAMES when it comes to AD's as the generics just don't cut it. Paxil CR 12.5 MG knocked out my depression and severe anxiety/PD within days. It's a good drug. If you need to withdraw from any SSRI use Lyrica. It's like a beta blocker for the brain and will cancel out any and all withdrawal symptoms from any SSRI/SNRI. For weight gain, sexual dysfunction associated with this or any SSRI take the herb Rhodiola Rosea. It's a miracle herb. M 39 2 years
12.5
6/30/2012
 5  OCD/Panic Disorder WEIGHT GAIN!!!! Gained 20 pounds easily within 2 years. Don't let anyone tell you it's not the Paxil CR. I was a competitive runner and STILL gained weight. I went on a 1,200 calorie diet for over a month and exercised 6x a week. I wrote down everything I ate and DIDN'T LOSE ONE POUND! Stopped taking Paxil CR and lost 2 pounds in one week while eating anything I wanted. With that said, Paxil CR eliminated my OCD symptoms. It was wonderful in that regards but I ended up feeling depressed when month after month I kept on gaining weight. I stopped taking it for that reason alone. I am now on Villbryd and trying to see if I can lose this weight. F 46 2 years
37.5 1X day
6/11/2012
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 5  Anxiety (GAD, Panic, OCD) Slight weight gain. Dry mouth. Entertaining dreams. Emotional numbness. Was basically non functional for 6 months because of anxiety and lost 30 pounds. Tried Lexapro and gave it 5 weeks. Only gave me headaches. Also tried Xanax and Clonopin and while they worked, I would very quickly get rebound anxiety which put me into a spiral of hell. Finally found Paxil CR and it returned me to normal in 48 hours. Probably had the best year of my life on this drug even with intense times of stress. Oh, and it almost completely cured my IBS. It does cause emotional blunting. You still feel the emotion, you just don't yell or cry. Tried tapering off and IBS came back. Back on it again and back to normal. M 40 1 years
12.5 1X day
3/8/2012
 5  depression, anxiety, hopelessness, Paxil was a life-saver back in December 1996. I was depressed, anxious, scared, lack of self-conference, driving my kids crazy, needy, going through menopause, rocky relationship, felt zero joy with living, felt like a loser, etc. etc.....within 48 hours of taking Paxil I was beginning to say to myself "this must be what it is like to be normal". My kids saw the change within 24 hours. I have tried going off Paxil but immediately feel myself falling back down that black hole. My question is: "Can I be on Paxil for the rest of my life? I am now almost 72 years old but doing ok. F 71 15 years
20 mg 1X day
1/25/2012
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 1  anxiety attacks Severe anxiety,tachycardia,palpations,severe depression I am a nurse and started having anxiety attacks was put on paxil CR 12.5mg.On the 5th day started feeling depressed which I had never been depressed before.Figured it was nothing took the pill on the 6th day.That was a big mistake.I have never had anxiety attacks like i had that day.My heart was beating at almost 180bpm I could feel it pounding out of my chest. I was histerically crying nonstop.I was having crazy thoughts and feelings in my head.That night was woken up thinking I was having a heartattack.In the 6 days I took the paxil I lost 8lbs and had bruises all over my body.Never took another pill again.Think before taking this pill it could make you worse. F 33 6 days
12.5 1X day
7/12/2011
 5  Depression F 63 15 years
5MG 1X day
7/5/2011
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 1  GAD and Social Anxiety While I was taking this medicine I didn't care about anything. My emotions were completely numb, minimal weight gain, no interest in sex. Others noticed I was withdrawn, but didn't say anything because they thought I was happy. When I decided after 6 years to not up my dose and actually wean off of it, the nightmare began. I had a HUGE rush of emotions that I couldn't control that had been numb for years, my head was fuzzy: I couldn't think, brain zaps. It was horrible!!!! It has been almost a year since I got off of Paxil and I am still trying to pick up the pieces over the past 6 years. Including my friendships and most importantly my marriage. I DO NOT recommend this medicine or anything that resembles it like Cymbalta. I now take Buspar and have never been happier! Well...as happy as I can be for losing 6 years of my life... F 31 6 years
30mg 1X day
3/19/2011
 4  ANXIETY & PANIC ATTACKS 20 pound weight gain; night sweats; excessive sweating throughout the day (not menopausal :)lol I'm a dietitian and personal trainer. I have weighed 118 for as long as I can remember. I was very depressed when I first started Paxil and I'm sure that started the weight gain with increased sleeping and lack of exercise. However, I know it has increased my appetite tremendously. I got over the depression within a few months, and it definitely calmed the anxiety and panic attacks. I did not experience any side effects getting off of it and am now trying Luvox CR just because of the excessive hunger and sweating. Yuck! F 34 1 years
25mg 1X day
2/25/2011
 4  Anxiety/drepression Weight gain {have to watch what I eat/walk several miles 3-4x per week}, fatigued, Lessened sexual desire. Well it's hard choosing between a healthier sex life, and lower weight, vs. feeling high-strung, moody, sometimes depressed and having anxiety attacks. The thing is I don't think there's any "perfect" drug out there because they ALL seem to have side effects of some sort, and guess we all just have to be our own guine pig so to speak to find out what works for you. So I've been taking Paxil for many yrs. now and it's truly helped me a great deal w/anxiety, and if/when I feel depressed bounce back quicker than back then. Plus get behavorial therapy. I must say exercise, yoga and taking vitamins helps too--esp. cod liver oil has helped me. So Paxil has become a part of a healthier emotional/mental life for me long ago. I've always been scared of getting off Paxil since I NEVER want to have another clinical depression as long as I live. I guess some of us just are more suseptible to this, just as some have other illnesses they have to cope with. The thing I like least abt Paxil is my decreased sex life. And that I feel fatigued w/less energy. Perhaps 10-15mg. would be a better dosage for me than 20mg. As far as weight gain, I'd probably have a normal weight of 130-136. But can't exercise a lot during the winter months [get way too tired during winter] so my weight sky-rockets up to 145. EEEK! Rest assured, once the weather breaks, it's very easy to drop 10 pds. from just keepin up on miles of walking. So, guess I'll still be taking it since my anxiety levels dropped F 45 15 years
20mg 1X day
2/12/2011
 2  anxiety tired, headaches, dizzy, blurry vision, emotionless, no sex drive, no motivation to workout, went from 130 lbs. to 145 lbs. Don't quit know if it is worth the unhealthy feeling and unhappy shape I've become. F 40 6 months
20mg 1X day
1/10/2011
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 5  Severe anxiety, insomnia, white noise, occasional headaches-but not sure if it's related to taking this medicine, Before I started taking this medication, I didn't know what was wrong with me. For about 6 months I couldn't sleep more than 4 hours per night, wasn't eating, food didn't taste or smell good. I constantly felt severe anxiety and tried so many things to feel better but nothing helped. My Dr. suggested I try Paxil and it took about 4 weeks for this medication to start helping me, but now I feel so much better. I really feel like it gave me my life back. I am loving my life again! F 42 6 weeks
37.5 mg. 1X day
12/27/2010
 4  PE Lethargy. I feel like I could stop and nap at any time during the day. I need to keep my mind occupied or I will start nodding off. No weight gain for me- which I've heard is pretty common. Vivid dreams at night, which are a nice bonus. I actually started taking paxil to help with premature ejaculation. I could only last a couple of minutes with my wife. While she never complained I'm sure she was frustrated, as was I. Since beginning Paxil, I can last virtually as long as I want in bed- The level of ejaculatory control is amazing. Since my wife is on prozac it takes her a long time to reach orgasm, and I now have no problem holding off until she gets there. Intercourse can easily last longer than 30 minutes. Anyone out there who is suffering from PE, I would highly recommend getting on this med. The only downside has been the lethargy. I am constantly having to battle the urge to nap. 5-Hour Energy helps a great deal. M 34 4 months
25 mg 1X day
12/16/2010
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 2  anxiety jumpy, numb/tingling hands and feet/ anxiety symptoms getting worse. M 42 2 weeks
25 mg 1X day
11/28/2010
 4  bad anxiety and depression Initially some sleepiness but nothing else. Eventually I did gain about 35 lbs. It made me hungry and not as motivated to exercise. If I had to, I would take this again. The only reason I stopped is because of the weight gain and hunger it gave me. Paxil CR saved me when I was only sleeping a few hours a night and having constant anxiety. Whatever you do, do NOT go off of this medicine cold turkey. Do it under an experienced physician (preferably a psychiatrist). There are withdrawals. My dr had me start taking my new med while I was still on the Paxil CR and I tapered over a period of three weeks. I still felt like I had the flu for about a week. But you know, it gave me 10 months of restful sleep and anxiety-free days, so it wasnt all bad. M 38 10 months
25mg 1X day
9/23/2010

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