MIFEPREX Reviews (MIFEPRISTONE)

Average Rating: 3.6 (68 Ratings)

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 Type: Rx Drug

  

MIFEPREX  (MIFEPRISTONE):  This medication is used to control high blood sugar in people who have a certain condition (Cushing's syndrome), and who have failed surgery or cannot have surgery to correct the condition. Cushing's syndrome is caused by the body producing too much of a certain hormone (cortisol) which can cause glucose intolerance or type 2 diabetes. Mifepristone works by blocking the effects of cortisol.   (Sources: U.S. Centers for Medicare Services, FDA) FDA Approval Date: 2000-09-28

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR MIFEPREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 5  Medical Abortion Felt weak. Heavy, heavy , heavy bleeding At 5 weeks I took the one pill on a Friday then on Saturday exactly 24 hours after taking the first pill I took the remaining 4. Two on each side of the cheek and let it stay for 30 minutes then swallow the rest. I waited an hour then took some percocet and I felt no pain. The bleeding and bloodclots however where alot. It is day 6 and I am still bleeding but not as heavy. Other than the heavy bleeding this is way better then going to the clinic and having it sucked out. It cost more but it is worth it and especially in the comfort of my own home and help. F 31 2 days
1X day
3/11/2011
 1  end pregnancy slight brown discharge I had a medical abortion 2 years ago using this. It worked fine...very minimal cramping. I went to have another a week ago, mifeprex does absolutely nothing (or did absolutely nothing in my case). I changed my mind after I had taken it and today went to the dr to find my baby is fine, heartbeat normal, everything. The other pills you are instructed to take is what really does it all but then again I've heard it all depends on how far along you are. I am 8 weeks now. F 23 1 days
600 1X day
3/9/2011
 4  Medical Abortion Very painful, heavy bleeding, blood pressure dropped low. Having said said that it was over quickly I was tired for a day or two. Would do it again if I had to. Feel my doctor could have told me how quickly the pain came on and how bad it would be but over in a few hours. I wasnt goingto tell my husband but I am glad I did as for a few hours it was bad. M 40 1 days
1X O
2/13/2011
 4  unwanted pregnancy severe cramping, vomiting, dizziness, brief loss of consciousness after standing up too quickly (MEDS: mifeprex/misoprostol, phenergen, percocet, xanax) I do not regret choosing a medical abortion over a surgical one. I will avoid an abortion clinic entrusting a doctor I've never met with my future fertility at all costs. However, my cramping was very severe. I have a high pain tolerance, and Percocet did not even begin to take the edge off the pain I experienced. Almost as unbearable as the cramping were the muscle aches in my legs. For me, it lasted somewhere between 4-6 hours. I continued to bleed for several weeks thereafter, but did not have any cramping. I have mild to moderate cramping during my periods, but did have stronger cramps when I was younger. Please note that I am in no way trying to scare anyone. This was my personal experience, and I would not hesitate to do it again. I just find it incredibly insulting that some of you would imply an experience like mine is somehow invalid based upon your experience alone. Unlike any other medical treatments, mifeprex/misoprostol is always administered as a one size fits all dosage. I suspect I am much more sensitive to the drug than most. If I had to do it again, I probably would not take all 4 misoprostol at once, due to my reaction to the drug. F 29
1X day
11/9/2010
 5  Pregnancy Termination I took Mifeprex on day 1, on day 3 I was instructed to place the 4 remaining pills in my mouth on the inside of my cheeks where they would dissolve for a half hour, then I swallowed what was left of the pills. After washing the pills down with water, I threw up violently all of the water and my body insisted I keep throwing up when there was nothing left to give (due to nausea in the first place). About 30mins later I started to experience the worst pain I have ever felt in my lower stomach and staggered hunched over to the bathroom where I immediately started to bleed in the toilet. I waited on the toilet for as long as my body would allow me to sit upright and flushed without looking. I was sweating heavily but was freezing at the same time so I wrapped myself in a towel. Back in bed, I could not get comfortable. I tried turning on each of my sides in a fetal position and nothing helped so I frequently changed positions, wincing in pain, and squeezed the covers around me tight. !!!PLEASE READ FIRST!!! MY PHYSICAL CONDITION LEADING UP TO MIFEPREX: During my 6th week of pregnancy I was very nauseous everyday. I had only been able to eat small portions of blan foods such as pretzels and was drinking chicken broth and water the week prior to taking Mifeprex. Still, I think my body was very weak and dehydrated which may or may not have contributed to the side effects. I strongly suggest gatorade and pretzels or crackers, they were my only comfort during this process. Also get at least two days off from work during the bleeding. With as much pain and discomfort I experienced, I do not regret my decision for taking Mifeprex and would recommend it to others. It was difficult but I felt 100 percent better in the following days. F 23 3 days
1X day
8/12/2010
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 5  abortion almost none. biggest worry was throwing up which i experienced a couple times a day. only very mild cramping and very brief bleeding and passing of bloodclots. didnt even take the prescription pain meds, just 2 advil and still felt alright. F 19
1X day
7/13/2010
 5  abortion i guess everyone is different, but i had very little pain form this. it was like a heavy period to me. i was 6 weeks 3 days. i had a little nausea the morning after taking the dose at the office, then on the 3rd day did the 4 pills vaginally to dissolve. about an hour later i had some mild cramping and passed blood clots for a few hours but that as well as the crampling stopped with in about 5 or 6 hours. it is now day 5 and i still have some light bleeding but i feel good. i was very thankful that i was about to have a medical abortion instead of surgical. do what is right for you. dont believe all the horror stories online. just talk to your doctor and i am sure they can let you talk with some REAL people who have taken it. good luck to all. i know it is scary but you will make it thru everything. F 32
1X day
5/25/2010
 5  early pregnancy termination minimal nausea and fatigue with the Mifiprex, moderate, but not intolerable cramping with the misoprostol I was very nervous about taking the misoprostol based on ratings here and other sites. Here is my experience: 5 pm- took Iburofen 800mg, 6 pm- took Percocet and Zofran (nausea), 7 pm- took misoprostol, allowing to dissolve in cheeks for 45 min, 8pm- mild bleeding, 10 pm-2 am- able to sleep, mod cramping, (feeling like I had the breath knocked out of me, in a way) took 2 more Percocet and 800 mg IBP. 9 am- cramping done, still had some bleeding with clots, but not painful. Much less traumatic than I expected, very little pain. I feel tired today, but am able to be up and about. F 37 1 days
1X day
5/3/2010
 4  To end an 8 week, 6 day pregnancy Hardly any cramping but unpredictable blood flow for 2 weeks now I was expecting the worst side effects per the clinician at Planned Parenthood - not from online sources. After taking the first pill at the clinic I felt nothing the rest of the day. After 24 hours I placed the 4 pills between my teeth and cheeks as instructed and waited. This wasn't a horrible ordeal. After 2 hours I thought it didn't work because I still felt nothing THEN came the gush. The passing of the "lemon sized clot" (as predicted by PPH) was a little shocking as was seeing all of the matter pass but from then on the bleeding was off and on. Tomorrow will be 2 weeks and the bleeding hasn't stopped but I guess that's expected. The only bad part of this experience (physically) is the unpredictable flow - today alone I had to change my tampon 20 minutes after insertion then nothing the rest of the day. I have had very little cramping - maybe a 3 on a 1 to 10 scale - and no headaches, nausea or vomiting... Everyone is different. I wouldn't base how u decide to term your pregnancy on other people's experiences. I do wonder if the women that had horrible cramps with using Mifeprex, have bad cramps regularly with their period. I very rarely ever have cramps. F 30
1X day
5/2/2010
 5  unwanted pregnancy in its 7th week Slight to moderate cramping which lasted for about an hour and a half. I was expecting the worst after all the horror stories I read online about Mifeprex but it turned out that I had stressed over nothing and the procedure was surprisingly not only tolerable but rather painless. I took two different strong painkillers half an hour before inserting the two misoprostol tablets vaginally, and experienced some slight cramping (I've had sharper and more painful menstrual cramps in past periods) which I napped through. When I woke up, I ate some breakfast and then over the course of the next two hours, I expelled a bunch of blood and clots with each trip to the toilet. The bleeding seemed excessive at first and came in big gushes at a time but according to the nurse I talked to it's normal. The bleeding tapered off significantly by the afternoon. I was so relieved afterwards how smoothly things went and was glad that my doctor talked me into this instead of the surgery. F 27 3 days
1/28/2010
 1  3 week 4day pregnancy termination BAD IDEA! I read one comment that said people write bad experiences are just trying to scare you- I am not trying to scare anyone I just want to tell the world to go surgical vs. pill!! IT'S NOT WORTH THE PAIN! My experience- I went to clinic in Austin, ultra sound said 3 weeks 4 days, which was EXACTLY correct to the day. (By the way, all abortion clinics make you stay forever so bring a book and blanket, you won't get out of staying there for 4 to 6 hours no matter where you go.) I took the first pill. No symptoms.. 36 hours later I followed all the instructions and took 1 vicodin and 1 promythazine and waited 30 minutes. Then I took all 4 of the 2nd pill. 30 minutes later I was sitting on the toilet using the bathroom, bleeding, had a fever, threw up once, and THE WORST CRAMPS OF MY ENTIRE LIFE. I found myself breathing as if I was in child labor. I was praying to God to help just stop the pain. I have a high pain tolerance, but this was not tolerable, it was beyond mental. -I WOULD NEVER HAVE DONE THIS HAD I KNOWN THE AMOUNT OF SEVERE PAIN I WOULD EXPERIENCE. (The pain was so intense, even if it was for 5 minutes of pain I wouldn't do it again.) -If you must do this, drink a lot of water before because you will sweat and vomit water during the process, and adding dehydration to this mix can't make it any better. -Massaging the uterus will help pass clots. -I HAVE A B.S. IN BUSINESS, I HAVE NEVER POSTED A REVIEW FOR ANYTHING EXCEPT MIFEPREX, TRUST ME- THIS OPTION IS NOT WORTH THE PAIN!!!!!!!! Get the surgery if anything! *one more thing- your hormones are going to be very out of balance and you will be crazy for a few days after this pill, also don't have sex after any abortion for at least two weeks because of suseptibility to infection and pregnancy. F 24 1 days
12/5/2009
 4  termination of a 4 week pregnancy From the mifeprex alone, I honestly didn't feel much different - just a growing dread of taking the misoprostol to complete the process. I admit I was terrified of having a bad experience like most of what I've read here, esp the one comparing it to the surgical procedure and how the pill isn't "worth it". I'm glad i tried out the pill option, really. It went like clockwork and the pain was completely manageable with my lortab prescription and anti-nausea pills. No diarrhea, never vomited, and my cramps were of moderate to heavy period strength. I sat on the toilet after I'd been bleeding lightly for an hour (this was 4 hours after taking misoprostol) and passed what I think was the gestational sac and placenta. Every few hours after this, I would drop clots that seemed large but not painful or suspicious and so on until I fell asleep for the night. That's it. My bleeding basically stopped the day after. Now, on that next day, I would try to keep in mind how traumatic in comparison to aspiration abortion, the pain here was NOTHING! my experience with the surgical procedure was not as easy as some like to describe, but then my recent trial with the medical abortion was a walk in the park compared to some womens' horror stories. i prepared myself for the worst mentally and physically, but was relieved with how easily the process took care of itself. i'm grateful to have had the comfort of my home and partner to guide me through the emotional part of it. the absolute worst moment in all this was seeing what my body passed into the toilet and the thought processes that followed. in that respect, i wish that the US handled medical abortion the same as in the UK - with women undergoing their "miscarriages" in a hospital setting and then sent home to recover. it seems a little more humane in terms of tissue disposal and monitoring of all the side effects that can occur just after taking the misoprostol. Don't be scared to try this because of the more intense and negative experiences you find researching online. Not to discredit what these women went through, but if you're in the category of those who have this pill option, don't put yourself through a surgical procedure if you can avoid that type of invasion and (very different kind of) pain. F 20 1 days
11/1/2009
 1  terminate 7 week pregnancy I experienced no side effects after taking Mifeprex, the "first" pill which actually stops the pregnancy. I waited the necessary minimum 24 hours before taking Misoprostol (the 4 pills that dissolve in your mouth) at 10 a.m. that started the rest of the process. The bad taste of these four pills is a walk through the park with what I experienced for the next 14 hours. I was given Vicodin for pain and Phenergen for nausea. I needed both. After a severe cramp, I usually expelled a very large clot. This went on for about 6 hours. Seven hours into the procedure I started very heavy cramping, bleeding and clotting. This did not seem normal. An hour later I experienced a gush of blood and tissue as never before. Didn't make it to the toilet in time. No fun cleaning up your own abortion while you're experiencing it. I became scared and called the nurse hotline. I described everything, she assured me that the worst is over and it will die down. I had two more "visitations" I regret my decision to do a pill abortion. I am an intelligent, professional woman. Ten years ago, I had a surgical abortion (suction) to terminate a 10 week pregnancy. Yes, the pill method does allow you privacy in that you experience the abortion at home on your own terms, but here is the crux of the matter - why suffer? Why . . . suffer? Whatever method you choose, you're still in control. In both cases, the doctors and staff at the clinics I went to were very professional, supportive, thorough, compassionate and listened well. A pill abortion involves very powerful medication. Once you start, you're own your own to make decisions that really should be made by trained medical personnel. Choosing an abortion is an intensely personal decision. Take your time before agreeing to a method. I am pro-choice. Never take your legal right to an abortion for granted. The choice? Terminate a pregnancy in 10 minutes with little to no pain, or choose (potential) hours of pain and bleeding. In my opinion, the most humane (think about this) method is a surgical abortion. F 45 1 days
10/4/2009
 4  Medical Abortion After taking the first pill, I had no side affects. I was actually worried that I was feeling too good. I was afraid the medication wouldn't work. After dissolving the four pills in my cheeks two days later, I had no doubts it was working. I was surprised by the intense pain of the cramping. I think it was the worst pain I've experienced, although, needed. They started slow at first, and then intensified for about two hours until I passed the tissue. I was given vicodin, which I took before hand, but I don't think I gave it enough time to kick in. Also, eat before you take the second set of pills!! I was horribly sick, and vomiting nonstop because they had upset my stomach.But, it is more private than a surgical abortion, and they highly recommended it because I was only 4 weeks pregnant. Overall, I think it was a better alternative and I'm still happy with my decision. F 19 3 days
9/5/2009
 4  terminate early pregnancy Cramps, tired, out of commission for a day I missed my period and went to the doc the next day. Much less traumatic than I thought it would be. F 22
7/27/2009
 5  unplanned pregnancy The side effects.. I went to the Dr's they did blood work, urine test and then ultrasound (all within 30 minutes) and found out I was exactly 6 wks 5 days pregnant. Dr. gave me the mifeprex pill to take orally which i did. Then handed me a small bag with the 4 misoprostol tablets and told me to insert vaginally within 72 hours. Side effects w/just the oral mifefprex were nausea and sluggishness but not enough to miss work or be in pain. I noticed a slight brownish discharge about a day after taking the oral pill but had no cramping until after inserting the 4 vaginal tablets I waited to insert the vaginal tab's because I went out of town so I waited almost 2 days after taking the oral mifeprex.The Dr. told me not to wait too long after because the abortion may not work...Woke up at 3am took Tylenlo 3 and waited... 4am, inserted the vaginal tablets and just went back to sleep, woke up at 8am and got up to use the bathroom and was already heavily bleeding with clotting. I did take the Tylenol 3 before inserting the tabs but the cramps were pretty strong..The really bad cramps lasted from about 8am to 1pm that day. Had to use a pad for the next 5 days because of heavy bleeding. I only took 3 more Tylenol 3 pills throughout the 5 days and mixed it up with ibuprofen and then midol. About day 4 I noticed some heavy cramps and pain in the abdomen but also discharged more clots with may have been the last of the embryo. It's now day 6 and I am almost done with the bleeding and cramps. I'm going in to get an IUD asap. F 37 6 days
7/25/2009
 5  early pregnancy termination 5 weeks I had zero side effects from the mifeprex(the first pill taken orally) 24 hours later I dissolved the 4 other pills in my cheeks. Different clinics use different procedures. Some give you 4 pills(Cytotek) that you insert vaginally. I had to dissolved them in my cheeks for half an hour. That itself wasn't too pleasant, they tasted horrible. Before the pills were even entirely dissolved I began to feel cramping in my stomach. This cramping became severe within about 2 hours. I had a prescription of 4 tylenol with codeine pills. That was all for the pain. Even with the codeine the pain was excruciating. Enough to keep me moaning and I had bouts of crying that I endured. Maybe after about 5 hours I began to feel better. Then I just slept. It took a lot out of me, however it worked. I had morning sickness before taking the pills,,,within about a day or two after, I felt like a million bucks. Besides the bleeding, that did last for about two weeks. Started out with a lot of F 29 2 days
4/21/2008
Email
 5   The pain medication (vicodin) gave me an upset stomach and made me tired but that was it. I had no side effects with the mifeprex its self. The cramping was no worse than a normal period for me, probably because of the vicodin. The "women" on here that say it was horrible and very painful are trying to scare you away from abortion. It's hard to find real patient experiences on the internet, this was the only one I could find. After reading these comments I was hesitant, just as the person below me. I went to the clinic. The procedures were easy and painless. The worst part was having a vaginal sonogram because the doctor couldn't see the pregnancy with a regular sonogram and it was only slightly uncomfortable for a couple seconds. You take the cytotec vaginally 3 days after your visit to the clinic at home and it does require you to lay down and not get up for 8 hours. My cramping started about an hour after I took it and I started to bleed 4 or 5 hours later. The cramps are mild to slightly painful and the pain medication helps a lot. I suggest clearing out your schedule the day after and having someone to help you that you trust. I was terrified of a surgical abortion and decided to try this is an F 19 4 days
4/11/2008
 5  unwanted pregnancy slight cramping (no worse than normal menstrual cramping), very little stomach discomfort. I went to the Houstons womens clinic and recieved ru486 after only a little research. when I came home I thought i would take a look at what other people thought of this drug and after reading just a few comments i was so frightened. People wrote of horrifying experiences and i was so nervous about the rest of the medication i had left to take over the next few days. But i made myself calm down to ensure that i didnt experience anything psycosamatic and i finished the drugs with no pain and very little discomfort. I am so pleased with the effects of this drug. I am beginning to believe that the only people that write on these bulletins are those who want to scare you away from abortion. F 19 4 days
8/10/2007
 1  termination of pregnancy too much pain, it has been 9 months how i had this procedure done, and since that time I got bacterial vaginosis that I tried to treat 5 times already and all unsuccessfully. I am sick of taking antibiotics. In spite I experienced such big pain that I wrote a letter to the Mayer about what pain women go through while taking those pills, and that hospitals don't give adequate pain killers and care (for 12 hours I did have any food or have an opportunity to use the bathroom : it was so painful that I couldn't move my body), now I got bacterial vaginosis form which it seems impossible to get rid of.. WRITE TO YOUR MAYER! MAKE A CHANGE! F 20 1 days
7/26/2006

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