MIFEPREX Reviews (MIFEPRISTONE)

Average Rating: 3.6 (68 Ratings)

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 Type: Rx Drug

  

MIFEPREX  (MIFEPRISTONE):  This medication is used to control high blood sugar in people who have a certain condition (Cushing's syndrome), and who have failed surgery or cannot have surgery to correct the condition. Cushing's syndrome is caused by the body producing too much of a certain hormone (cortisol) which can cause glucose intolerance or type 2 diabetes. Mifepristone works by blocking the effects of cortisol.   FDA Approval Date: 2000-09-28 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on MIFEPREX: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR MIFEPREXCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 3  Medical Abortion Vomiting, Sever cramping and contractions, chills, sweats, 10/10 pain I went to the sketchiest abortion clinic in the world and was given 1 pill in office and instructed to let the other 3 pills dissolve in my cheek 2 days later. Those were literally my only instructions. No pain medication. No antibiotic. Told it would be like a period. I was 5 weeks along. So on the day I was instructed to take the remaining three pills, I started bleeding slightly right before I took them, was able to take 3 of my friend's leftover vicodin (5's) and then took all three pills, let them dissolve one at a time, all were ingested within 5 minutes. Walked into my kitchen to heat up my cornbag expecting cramping, but not to the severity that they were. Within 5 minutes of standing in my kitchen, I my uterus began cramping and I rushed to my room to lay down. I got really sweaty and achey, and I rushed to the bathroom and dry heaved and vomited 8 times. Then, I experienced literally the most excruciating pain I've ever felt in my entire life. I was laying on the tile floor and uncontrollably moaning and yelling and sobbing and kicking my legs and just putting my hands on the tub side because it was cold. I was dripping sweat and could feel my body going through contractions. I don't know if I took them too fast or what, but I read as much as I could online and saw nothing like what I was experiencing. After an hour of agony, I was able to get to my bed and just cry out of panic for an hour. But after that, the pain dulled to a 4/10 and really only exceeded F 20
1X day
8/12/2013
 5  Unplanned pregnancy First off, I want to Start by stating that this is a excellent choice for a woman who is doing this for the first time, it basically causes you to have a miscarriage. Day one: I went to a clinic my doctor referred me to, and there they had me fill out paperwork regarding the experience/ consent form. Then I waited in the waiting for a moment(horrified ofcourse) I was called in by the nurse into the room where they gave me a ultrasound. Using a probe. It determined I was 6 weeks and 2 days pregnant. They were able to see on the screen there was a embryo present. I went back into the waiting room, later I was called in to do a blood test to determine my blood type. Then back into the waiting where then a counselor called me in to a office where she had a personal talk about my decision. She asked me over and over again if I was 100% sure about the medical abortion, I assured her that I have never done this before, and that I was to scared to do the surgical. She went over the facts about the pill. Afterwards I went back into the waiting room where I waited 2 hrs. The nurse called my name, I went In to a room where the doctor gave me a pelvic exam to make sure my uterus and everything else is in place. It only took 5 mins. They gave me the first pill to take In the office with ginger ale. The doctor reminded me that cramping may occur instantly or hours later, or maybe after you take the other set of pills the day after. I was sent home. Didn't feel much pain, but was very nausea F 23 1 days
3/13/2013
 1  Medical Abortion I took the pill in the office. The nurse had asked me several times if I was sure about it & I told her definitely. Nothing happened... the next day I took the 4 by cheek. I threw up not too long after they dissolved. I waited for a while but nothing happened so I got a warm compress, put it on my stomach, after 5 mins my lower abdomen felt heavy. I went to the bathroom where clot after clot came out. Fast forward to a month later, I was still letting out clots. Couldn't walk small distances & almost blacked out on the train. I went to the hospital where I found out that my hemoglobin was at 5 when it should've been 13. I was severely anemic. I spent 3 nights in the ER & had a blood transfusion. 2 yrs later & I still expect to see clots when I'm on my period. I wouldn't recommend this to my worse enemies F 24 1 days
1/14/2013
 5  Medical Abortion Vomiting, Severe Cramps, Uncontrollable Shaking I felt nauseated after I took the first pill at the Dr.s office and was very reluctant to take the other 4 pills because of everything I read about the drug. 24 hrs later I took the 4 pills in my cheeks and waited. About 1 hr later the Cramping started. I cannot take Vicodin because it makes me sick so I asked the dr. to prescribe me something else so he gave me Tylenol 3 with Codeine. This was the worst mistake. The tylenol kept wearing off during the whole ordeal which lasted 12 hours and was very painful for me. I couldnt stop shaking and during the most painful moments I was walking around my living room in circles crying because the pain was so bad. I also was breathing just like I was in labor. It was terrible. Throughout the whole ordeal, I bled very little and at about the 4th hour the sac came out but I was still in pain and had severe cramping for the next 8 hours. I finally was able to fall asleep and the next day I just felt really sore. Overall, Im glad that it is over and it worked.The only advice I can give is take the strong pain pills. I feel like it would've been a more tolerable experience if I would've just listened to the Dr in the first place with the Vicodin. F 27
1X day
11/12/2012
 1  Medical abortion Vomiting. Diarrhea. Chills. Uncontrollable shaking. F 31 1 days
1 pill
11/7/2012
 5  Unwanted pregnancy I was definitely nervous before going through with this method but, I am happy to say that is was so much easier than I anticipated. I took the first pill at the clinic I decided to go to. I was told I was 7 weeks and 1 day along. I didn't feel any side effects at all except for how I was already feeling (fatigue and nausea) due to the pregnancy anyways. The next day at 3:30 pm I took the 4 mifeprex pills (2 in each cheek for 30 mins to dissolve) as told. I was pleasently surprised that they did not taste like anything so it made it much easier. After the 30 minutes I drank some water to swallow what was left and immediately threw up. I think it was due to the consistency of the pills. About 2 hours later I felt a gush into the pad. I bleed heavily for about the next 4 to 5 hours. The most uncomfortable thing of the whole ordeal was everytime I sat on the toilet large amounts of bloodclots gushed out which freaked me out feeling. My cramps were minimal, I had taken the pain killers beforehand which definitely mustve helped. At about 11:30 pm the bleeding almost completely stopped and was like a light period. Next day I felt kind of tired from being up late but very relieved and much better. This is a great choice for anyone wanting to do this in the privacy of their home and very worth it. F 24 1 days
1
10/12/2012
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 5  Abortion I was told I was about 5 weeks 4 days (based on missed period) pregnant. I believe I was only 3 weeks 5 days pregnant (based on possible conception date) . My sac measured 7 or 8 mm not exactly sure. I took the mifeprex in the drs office felt nothing. No bleeding or anything. 2 days later i went back and the dr inserted 2 tabs of misoprostol (sp?) vaginally. I was told to take 2 more of the same pills by mouth 2 hours later. About an hour before I had the pills placed vaginally i had taken 4 200 mg ibuprophen pills. I felt slight cramping and bleeding about 2 hours after receiving the misoprostol vaginally. It started with the sac passing then bleeding fresh bright red blood. After 2 hours I took 2 more misoprostol pills orally. Just swollowed like normal pills. Then after everything i just bled like a light period. Not even filling my pads all the way. I was worried that i wasnt bleeding enough. I kept taking the ibuprophen every 3 hours id take 3 then the 4th hour id take one more. I didnt want to feel anything !! I also took 1 vicodin which did nothing. I went to sleep after this. The next few weeks i bled like a normal period then i had some spotting. It was a natural experience. Now. Im a Catholic. Grew up Catholic my whole life. Even in pro life clubs and went to the marches yearly in DC. You dont know what its like until you are in a certain situation. You can never judge anyone. I feel stupid for ever wanting these rights to be taken away. I think that every woman sho F 24 1 days
9/15/2012
 5  abortion My doctor prescribed mifeprex to take for the first dosage, and 4 pills of cytotec to take the following day. I took the mifeprex at 4pm, and felt nothing whatsoever. The following evening, at about 10pm I was watching TV on the couch and felt a gush of blood leak out into the pad. I went to the bathroom and sat on the toilet, and immediately started bleeding heavily. There was still no pain, but it was obvious that the abortion was in progress as I could feel the blood clots falling into the toilet. This continued for about 2 hours and then slowed considerably. The next morning, there was still no pain, and one last clot (which appeared to be the grey/white gestational sac) fell into the toilet. This same day at 4pm (48 hrs after mifeprex) I took the 4 pills of cytotec orally and let them dissolve. About 30 minutes later severe cramping begun, but not more than a heavy crampy period. The cramping lasted until about 11pm that night. Bleeding was only moderate during this whole evening, I assume because I had already aborted the day before. My experience with this procedure was an overall 100% satisfaction. I was 6 weeks and 4 days upon taking this medication. F 26 1 days
1X day
8/10/2012
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 1  Terminate pregnancy It seemed to work. 5 days after taking Mifeprex, I woke up with the worst cramping and abdominal pain I had ever experienced. I called the clinic emergency number. The nurse told me additional cramping is not uncommon. I cried in pain for many hours. I knew this pain was not normal, but after talking with the nurse I thought I could suffer through it. I had some heavier bleeding, then it seemed to subside. I went on with my day. I never imagined what would happen next. I woke up at 5 am and had hemmhoraged so much blood that I went into shock and lost consciousness. After a trip to the ER, 7 bags of fluid, an overnite hospital stay, and continued bleeding for 7 weeks, I don't recommend this product. F 37 1 days
6/7/2012
 5  Medical abortion Cramping, gas, nausea and vomiting, HEAVY bleeding. F 20 1 days
3/7/2012
 1  abortion After the first pill nothing, but after the 4 that melt in your mouth i had heavy bleeding and mild cramps it didnt work, im now 5 months pregnant F 27 1 days
1X day
2/14/2012
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 4  Medical abortion, 5 weeks & 4 days Very painful for 3 hours Another story focusing on the pain- not meant to repel women from choosing this method, but to advocate for having physical and emotional support nearby, just as you might for normal labor. I was 5 weeks and 4 days pregnant on ‘day 1’. I took the Mifeprex at the doctor's office, and inserted 4 tablets of Misoprostol (vaginally) 15 hours later (within the 12-48 hour recommended window). For 1-2 hours after inserting the Misoprostol there was not much action (light cramping). Then it began- nausea, severe uterine pain on par with labor contractions, diarrhea and vomiting. I took 1 vicodin but likely vomited it before full absorbtion. This phase lasted for 3 hours. The passing of blood and clumps was expected, the high level of pain was not- it was on par with childbirth. I had no idea that this would be the case. After those 3 grueling hours I reverted to cramps (as strong as my most painful period, but manageable with a hot water bottle and 2-3 tylenol) and continued bleeding for several days. Ultimately, I feel satisfied to have chosen the medical vs. surgical version, but if I had to do this over again I’d have a midwife present. Next time someone sends me home with ‘just-in-case’ bottle of narcotics, I won’t be so naïve! F 32 1 days
200 mg 1X O
1/14/2012
 5  Medical abortion I did not experience any symptoms until I took the 4 abortion pills roughly 26 hours later. Within the hour I experienced moderate cramping that came in waves and lasted only a few minutes at a time. I passed the sac no more than 2 hours later and the cramping stopped altogether shortly after that. The bleeding also slowed but was never really heavy to begin with. I know everyone's body reacts differently but for me this was virtually painless and I would recommend it to anyone. F 24 1 days
1X D
1/8/2012
 4  unwanted pregnancy This is the second medical abortion ive had and this one is the worst. Idk why everyone else had them melt in their mouths i had to insert mine vaginally after takibg one ib the drs office. I woke up from a dead sleep 3hours after placong the pills internally covered in blood and in so much pain even laying in a ball didnt help. I chose this option again cause thr first time it was like nothing. I would recommend this deffinately but make sure u drink lots of water as for me i threw up the entire 24 hours before internally placing the pills. And take ur pain pills as directed as well goodluck. F 20 1 days
1/6/2012
 5  abortion i was given the drug at the abortion clinic. everything was fine. however i took it on an empty stomach and kinda felt dizzy after. then i took misoprostol 4 total inside of my cheeks. let it dissolve inside of my mouth. after an hour of taking it i threw it up. was real scared that it wouldnt work but it did. all of a sudden i got really bad shakes and HORRIBLE abdominal cramps as well as sharp back pains. it felt like contractions. i delivered a child before and know how it feels. the pain felt unbearable!!! i took 2 ibuprofens and it did NOTHING for me! i continued to toss and turn in my bed. then the bleeding came...it was really really heavy. i soaked in 2 pads in an hour. looked thick and buncha blood clots came out. i laid back down and put a warm pad on my belly. then the pain came back even worse then before. i felt a strong urge to push. ran back to the bathroom and as soon as i sat down something heavy came out of me. i got up and seen the baby sack. it was as big as an actual egg. everything on the inside of it was see through. i hunched over the toilet and cried. this is not for the faint of heart...it took me by surprise. after i put myself together i laid back down and the pain stopped within the next hour, after that light bleeding of blood clots but not like before. overall the drug did what i needed it to do... F 27 1 days
1X day
1/3/2012
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 5  Medical Abortion I took Mifeprex on a Thursday afternoon. By Friday afternoon I was very nauseated but was able to work through it all. About 30 minutes before I took the misoprostol I did throw up but I think it was from me taking my antibiotics on an empty stomach. After putting the Misoprostol in my cheeks I was hit with another wave of vomiting and barely kept the misoprostol in my cheeks. After throwing up about a dozen times I was fine and went and laid on the couch with a heating pad. I fell asleep for about 2 hours and woke up with some moderate cramping and had a mild urge to push. I did and passed the sac. I am only about 6 weeks along and the sac was the size of a golf ball. It was pretty obvious it was the sac as it was a light gray color and very different than the other clots. I've continued to have mild cramping but nothing unbearable. I've only needed to take pain meds once. I pass a lot of clots when on the toilet but barely any on the pad. This was by far a better option than surgical and much less painful. Well worth the additional price! F 28 3 days
200mg
12/3/2011
 4  abortion The first hour or two after taking the four pills I had HORRIBLE cramping. I normally have high pain tolerance, I experienced kidney stones & all that was to me was uncomfortable, but these cramps were really bad. After the hour or two of cramping, it died down to regular period cramps. Every hour I would apply heat to my abdomen which helped a lot. The pain meds didn't really do anything for me but make me sick. It's been 7 days since I took the last 4 pills & I still have heavy bleeding & clotting but overall, it was SO worth it. I would recommend it to anyone in a situation like this. F 19 2 days
1X day
9/21/2011
 5  Abortion After the Mifeprex, I felt nothing until about 17 hrs later. Then, heavy bleeding began, but it was painless. At 7 wks, 3 days. I took a Vicodin and over-the-counter nausea medication at 7:45pm after eating a full dinner. At 8:35pm, I placed the 4 cytotec pills in my cheeks and spit them out at 9:05pm. Felt nothing until 9:25 when I felt moderate cramping and ran to the bathroom to throw up. Lost my dinner. The cramping got stronger and was painful, but bearable. Some light diarrhea and fever-like chills/sweating followed that was short-lived. I heated a water bottle for my abdomen, was drinking lots of water to replenish, and curled up with the bottle in bed around 10:30 and was able to sleep. The cramps had lessened. I woke up at 1:45am with heavy bleeding, clotting and mild to moderate cramping and sweating again. I took 1 more Vicodin, drankna bunch of water and went back to sleep for hours. I woke up with no cramps or nausea, just bleeding. Is this an unpleasant experience? Yes. Was it bearable? Absolutely, and it was completely over after a few hours. There is no more "humane" way to have an abortion. Abortion is inducing early labor and expelling a fetus. That being said, I'd recommend this process to a woman considering abortion and would tell her that she will be fine in no time. F 27 1 days
200mg 1X day
4/8/2011
Email
 3  abortion extreme abdominal pain the 1st night (about 3 hours after placing 4 pills inside my cheeks) and very heavy bleeding for the 1st 24 hours. About 3 hours after placing the 4 pills inside my cheeks, I woke up in middle of the night with the most severe abdominal pains. It was honestly the worst pain I ever felt in my entire life. I saw the embryo fall out when I went to use the bathroom and I nearly fainted/blacked out from the pain. F 23
1X day
4/3/2011
 5  pregnancy termination Four weeks pregnant: One strong contraction with a gush of blood accompanied by diarrhea. No other problems. This review written 31 hours after taking misoprostol. After all the terror I suffered preparing for this ordeal (my first experience with birth control failure, religious upbringing, etc) I'm so happy. Day one I took the Mifeprex in a clinic. I asked for pain and anxiety meds. I felt great for the next two days, no side effects. After ~52 hours, I took a Vicodin, waited 30 minutes, placed the misoprostol between my cheeks and gums. One note - I only weigh 100 pounds so I took the liberty of reducing the dose from 4 to 3 pills without consulting a clinician. I was afraid of the severe pain I've heard of others experiencing. The 3 pills took an hour and a half to dissolve, which I didn't expect, therefore waited that long to take a 600 mg ibuprofen chaser. Even after that, I felt only minor lower abdominal cramps, and was so comfortable I got hungry on hour three and went out to dinner. Luckily I wore a pad because as soon as I began to eat I had to run to the bathroom as it felt like I had diarrhea. For about 10 seconds on the toilet I worried because it was really bad cramping, but it went away as fast as it came. I went home (finished my food!)waited for anything bad to happen, but there was just bleeding when I sat on the toilet. At about 11 hours, I woke up and took 2 Advil for minor cramping, and went back to sleep. I then got up and went to work this morning like a normal day. Have had clots and thick bloody discharge when I pee but minor spotting on the maxi pad, no pain. Feeling emotionally better than I have in 2 weeks. F 38 1 days
1 1X day
3/14/2011

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