SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  Bipolar Anyone who has had restless leg issues with seroquel have your doctor prescribe a low dose of requip and it will knock it right out. It is due to the dopamine blockade to which it is the weakest binding compared to others in its clas. This is actually not commom w/ seroquel but requip will get rid of it! F 42
8/4/2009
 4  Depression, Bi Polar When I first started taking Seroquel I was exhausted....like I had been given a tranquilizer which is why it's advised to take at night before bed. After about four days the sleepiness went away...I have noticed sweating a bit more than usual and definite constipation...I occasionally notice dry mouth and nasal congestion but that is minimal This drug I have to say has really helped me more than any has...I have dreams more than I've ever had before and a definite decrease in my sex drive but I could give a crap if it improves the quality of my life.....I am concerned about reported side effects such as diabetes, high tryglicerides, and high cholesterol. I prob. need to see my doctor and have blood work done... M 35 2 months
7/25/2009
 4  Mood swings, insomnia. Severe exhaustion, difficulty waking, grogginess, irritability, increased hunger. I was placed on Seroquel first, and experienced severe hunger and also exhaustion and difficulty waking, etc. Then I was placed on ADHD medication, Strattera, which causes a severe loss of appetite, so that fixed the hunger also. F 22 3 months
6/25/2009
 4  bipolar mixed episode Initially the side effects were well received. Felt a little drunk after taking initial dosage. Could sleep like I never sleep before in mu life. Food cravings do kick in and are difficut to control. I've gained 25 lbs in 6 months along with unplesant bloating. Seroquel help me recover quickly from a bipolar mixed state. Allong with severe PMDD. For the firt time in my life I felt anxiety free anc not all mixed up. I am concerned about continuing Seroquel F 42 9 months
6/17/2009
 4  Insomnia, OCD, Claustrophobia Dry Mouth,bit tired, not many side effects since use only 25Mg-50MG This drug helped me alot for insomnia which Neurontin and any SSRI didnt do for me. In addition, it helps my mood which paxil and lexapro failed to do. I haven't noticed the weight issue as some have, maybe because i take low dosage and also take Neurontin. My doc says it increased blood sugar, so ideal to limit sugar intake while taking this drug. I think this drug is good alternative than the addictive Benzos as Xanax and Ativan. I feel confident taking this drug to make me fall asleep in long flight trip soon. Yes this drug can help alot. M 33 2 months
6/13/2009
 4  Bipolar, Anxiety, Insomnia Only take 25mgs at night AS NEEDED (in other words, my shrink doesn't want me to take it all the time) and I sleep. My only side effect has been to have my thoughts calmed, getting me off to sleep quickly and easily, for an 8 to 10 hour stretch. I've never slept much at night in my life due to my Asperger's, anxiety, Bipolar, and a few others. They all caused such extreme insomnia, I thought I was lucky to get a total of 4 hours sleep in any given 24 hour period, and that I was doomed to that for the rest of my life. I currently take Lithium, Welbutrin, and Ativan (also as needed), and between them all, including the Seroquel, I'm a balanced, capable, functional person. I feel like I could return to nursing if I wanted to now. F 30 12 times
6/3/2009
 4  severe generalized anxiety the first week I was a zombie but after about a couple weeks, that tapered off and I was fully functioning. weight gain but not much if you work out a little - I feel like this drug is for me, a miracle. I was taking 6mg of Xanax/day but my thoughts would not stop racing and I felt like I never wanted to leave the house. After a few weeks on this, I was sleeping normal, acting normal. All I can say is that this drug works for me. It's only a little difficult to say how much because I also take 8mg of Klonopin and Effexor XR. I took Paxil once and robbed a grocery store and went to jail. I'm not a robber and it was like the whole thing was an out of body experience. Until I was sitting in a jail cell wondering what the hell happened. Nobody would believe me but I knew it was the Paxil, I just don't go rob stuff, it was crazy. The seroquel noticably leveled me out and works for me. But I swear, the only thing that relieves my most severe depression is marijuana and if that were legal, I think it would be the only drug I would need. M 35 3 years
5/24/2009
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 4  bi-polap 1 I'm prescribed to take this med at night. This med has helped me GREATLY when it comes to sleeping. I don't mind the vivid dreams, I'm just glad I can sleep with almost no wake-ups in the night. One thing I did notice was that if I take my full dose at once, I get a feeling similar to restless leg, or more accurately, for me, restless shoulder, which doesn't happen if I take 1/2 dose, then the other 1/2 in an hour or so. The major problem I've had is WEIGHT GAIN...35lbs in 2 years. It seems that after I take my dose, I get strong feelings of hunger, so I end up eating late, which is likely part of the reason weight gain is a problem for some. It's a major case of "munchies". Why this med seems to cause "the munchies" I don't know, I just know that it's real. Unfortunately this sometimes leads me to fall asleep before I can get my teeth brushed. Which isn't doing my teeth any favors. F 39 2 years
5/24/2009
 4  Major depression (debilitating) Initially placed on 600 mg. I gained 50 lbs in 3 months but the gain was mostly water (edema). I was swelled up. After reducing the dose to 100 mg. I dropped 35 lbs in one month and now am 10 lbs. lighter than when I started. I have some nasal congestion and (infrequent) restless legs (but exercise helps a lot with that) and am foggy for the first 3 hours in the morning. I also take 180 mg. Cymbalta. Those of you who are experiencing drastic weight gain should consider the possibility that it's mostly fluid retention (edema) and talk to your doctor about reducing your dosage. At 100 mg. I am getting about 75% of the benefits I was getting at 600 mg. but without the weight gain. M 46 5 years
4/26/2009
 4  insomnia/depression/anxiety I take seroquel mainly for insomnia, I only take 25mg per night and that works great for me. I take 75mg of effexor per day too, in combination with 1.5 mg of clonazepam per day I am a far better person now. I am happy go lucky getting my sleep, not suffering with anxiety and am able to deal better with my life. You can get a little groggy in the morning, just make sure you leave 1o hrs aside for sleeping, this covers the hour you feel groggy in the morning. F 42 90 days
4/22/2009
 4  BP,Rage,Depression,Bizarre thoughts A bit sleepy during the first month. Now taking 50mg morning, 50mg night. Started with 25, and went up from there until I felt good. Also take 300mg 5-HTP, 900mg St.John's Wort, 20mg Lithium Orotate. Seems to be a great, side-effect free cocktail. Great sleep, great dreams, much calmer and happier. Still enjoy life, but not worried about freaking out. Have been taking all the other things for about 2 years, but still needed something to "take the edge off" and Seroquel seems to be the answer. F 47 2 months
4/22/2009
 4  to control bi-polar upswing Normally I take 50mg, but when the daylight increases, I go through a tremendous high. In March '09, I increased it 25mg at a time 'til I got to 175mg! I am down to 150, but recognize that I am still in a danger zone so haven't reduced it any further yet. I can't take more than 50mg at a time because I get leg tremors when in bed. I've been stretching out taking the doses starting in the early evening. I am wondering if I took them throughout the day (morning noon and night), if would help curb the eating binges I seem to go through at night. I am not sure if my inability to focus is because of the Seroquel or because of the mania of the upswing. I suspect the latter. At night, I take Seroquel, 300mg gabapentin (Neuronton, for mood stabilizer) and for depression, 75mg Effexor XR (because of its cost, sometimes venaflexine, the generic, a pill that has to be split and taken a.m. and p.m. because of the "half life"). In the morning, I take 300mg lamotrogine (FINALLY the generic of Lamictal is available, MUCH less expensive) for mood stabilization. I know how bad my bi-polar upswing can get (I was hospitalized, involuntarily, for more than 2 wks in 3/03), so I realize that I MUST take the Seroquel when weathering one of these episodes. IS there another drug to replace it that doesn't involve weight gain? F 56 6 years
4/20/2009
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 4  Bipolar/ Anxiety Major, weight gain (fast) At first I felt out of it , fuzzy and disconnected from reality, now I sleep well but now have NO dreams (which sucks), Memory problems, but severely increased focus It comes at a price if you are in a fix with moods and manic phases you must sacrifice your weight/looks to feel better,but then of course in turn you feel worse with decreased self esteem. F 22 2 months
4/15/2009
 4  OCD, GAD, INSOMNIA None so far, except sleepiness, which I wanted. A lttle dizzy, but overall great. There is such a wide range of likeability with Seroquel. Some people complain that the weight gain was horrible, yet have been taking it for years. That's difficult to comprehend, if it causes weight and health issues, stop taking it. There are always other options. Anyways, I am on 25 mg at night, and it seems to be helping a lot. F 21 5 days
4/3/2009
 4  anxiety depression weight gain (30lbs), extreme dry mouth, joint pain, some hair loss, episodes of difficulty swallowing,hard to get out of bed, sleeping 9 to 12 hours a night, lack of motivation I've been taking 300mlgs a night for 3 years. This medication has stabilized my mood very well. Depression has been a problem since my teens, but the extreme anxiety I use to have drove me nuts.Recently realized how many side effects I was having. So I am cutting the dose in half. My doctor is concerned about the risk of diabetes. I might go off of this completely. It is frustrating to find something that does work, but has intollerable side effects. Being able to sleep has been a blessing, but I do not want to sleep my life away. F 54 3 years
3/25/2009
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 4  Sleep trouble. Too groggy the next day if take too much. Can last many, many hours... I take Seroquel to counter the insomnia side effects of Wellbutrin. It definitely helps me stay asleep longer. HOWEVER I seem to be extremely sensitive to it and can take only mini amounts. I take the 25mg tablet and cut it into quarters and then try to make those little pieces even a little smaller. So, I'm taking only, like, 5 or 6mg of it. If the piece is too big I will still feel sedated and somewhat hung over way into the next day. The effect can last more than 12 hours, for me anyway. It definitely works but can be too sedating. F 41 3 years
3/19/2009
 4  Off Label for Anxiety/Depression I started taking 50mg at night before bed two weeks ago. First night started at 100 and it knocked me flat out. Woke up with BP of 81/57 and thought something major was wrong. 2 weeks later I've still got a fair amount of fatigue and weakness as well as a major desire to do nothing but sleep! After the major side effects stopped, this drug in addition to 10mg of Lexapro has been a lifesaver. I was having MAJOR anxiety issues and thought that I was going to go totally crazy before getting on this medication. I'm really hopeful that the side effects will continue to lessen so I can get back to a normal day's activities without wanting to take a nap. This is much better however than wanting to die, so all in all I'll take it. M 28 2 weeks
3/14/2009
 4  bipolar ,anxiety, mind racing, ect. I have experienced eye twitching, restless leg syndrome realy bad,extreme hair loss,feeling extremely hot when waking in night or amto the point of not being able to move easily. go out in winter in shorts to cool off 10 min. or once I'm up moving around for 10 min. it goes away.at 50- 100 mlg. at 300 mlg, massive head aches. Had to drop back down to 100 mlg. joint pain, head aches once a week lasting 3 days. This drug works for my anxiety and depression and sleep at night. I take at night so if I don't go right to sleep, or wake within a couple hours I get the late night feeding frenzie, but I don't eat much during the day, so this is probably nutritionally good for me though I have eaten some crazy things at this time and vaguely remember what. I have to go off this med couse of hair loss and twitching, and feeling so old but am scared of other meds too. This takes care of a big portion of my symptoms but causes damage.been on for 2 years. F 38 2 years
3/10/2009
 4  Not Sleeping Initially very hung over in the morning but that passed after a month. Still have the dreamy feeling and a little spaced out in the morning. I take 50mg at night and after about 45 minutes the wave of calm nothingness washes over me and I drift away. If anything happens after that I can’t remember it. I think seroquel is a very serious medicine. I also take 20mg of Lexapro and 4mg of Klonopin each day. I have been having trouble thinking and am wondering if the Seroquel is part of the problem. Thankfully I have spell check as my spelling is not as good as it once was. I am more calm and can relax better than before taking Seroquel. M 57 1 years
3/10/2009
 4  Imsomia I am concerned about the blood sugar rise possibility of other serious side effects. This is definitely the most potent sleep med I have taken (though it is NOT FDA approved for sleep) I would like to get off of it but have to say my sleep suffers without it. My problem with sleep is that I wake throughout the evening. Seroquel does not solve this but it does make it easy to fall back asleep. Its very hard to get out of bed when taking this medication. I am going to explore other options including a new drug that targets the sleep / wake cycle, and its approved for long term use. My true advice is to use this med with extreme caution and stop it if possible, depending on your condition. M 42 21 days
3/3/2009

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