SEROQUEL Reviews (QUETIAPINE FUMARATE)

Average Rating: 2.9 (1505 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

SEROQUEL  (QUETIAPINE FUMARATE):  This medication is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder, sudden episodes of mania or depression associated with bipolar disorder). Quetiapine is known as an anti-psychotic drug (atypical type). It works by helping to restore the balance of certain natural substances (neurotransmitters) in the brain. This medication can decrease hallucinations and improve your concentration. It helps you to think more clearly and positively about yourself, feel less nervous, and take a more active part in everyday life. It may also improve your mood, sleep, appetite, and energy level. Quetiapine can help prevent severe mood swings or decrease how often mood swings occur.   FDA Approval Date: 2005-10-04 (Sources: U.S. Centers for Medicare Services, FDA)

  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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More on SEROQUEL: Reviews Summary  |  Drug Safety Information

RATING  REASONSIDE EFFECTS FOR SEROQUELCOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  BPD II, depression, insomnia, mood Some restlessness during the night. First night woke up several times and had some trouble getting back to sleep. Second night woke up less times during the night and fell back asleep easier. Did have some night sweats. Was very groggy in the morning after the first night and somewhat out of it. Second night I made sure to sleep longer (10 hrs) and felt much better, less groggy. After half a can of red bull felt great! Did have severe headache on first day. Feel less hungry in general. Some dry mouth, I just drink more water :) Recently diagnosed with Bipolar II w/manic episode and rapid cycling, depression, mood disorder, anxiety. Had insomnia, anxiety, and BPD for years undiagnosed and managed them with other substances. Been on lamictal 100mg for 2 mos, and just started titrating up to 200mg. Right now on 150mg lamictal, flexiril 5 mg and vicodin 5/500mg for back and hip injury in car accident. Since taking seroquel I take flexiril and vicodin only as needed. This drug was prescribed as a sleep aid after being on Ambien 10mg for about 1yr and was no longer effective. Even thought I have taken this drug for only 2 days I feel great! I feel so happy again and feel like my old self, the person my husband fell in love with. I am joking and happy-go-lucky again. I feel much less anxiety, agitation, and irritability throughout the day. I would get so angry and anxious and have serious mood swings that the lamictal alone couldn't control. If prescribed this drug, try it and perhaps keep a journal of your symptoms. It seems this medication is right for only a small population of people w/our problems. So far the benefits outweigh the side effects for me, but i will monitor my feelings and symptoms closely. All I know is I am excited and happy for what may come :) F 25 2 days
25mg 1X day
2/4/2010
 4  Bipolar and sleep issues Weight gain Seems the longer I've been on it, the less it helps me sleep. When I was on 25 mg the first 5 years, I slept great and didn't have any weight gain. I'm on 300-600mg at night now, and have put on 50 pounds. F 53 12 years
1/25/2010
 4  I am Bipolar who does not sleep I was perfectly happy with taking seroquel until my eye dr. told me that I now have cararacts I like so many others I do not sleep. I can't go to sleep. I lay there for hours on end. I have been known to stay awake and alert for 2 weeks at a time. My Psyc. put me on seroquel. we played with dosage, tweaked and added trazodone. I sleep better but still have nights where I only reach lala land. Yet I feel rested when I get up. Now I find out that I have caratacts caused by seroquel. I will have surgery to replace the lenses in my eyes. But what other drugs are out there to cause me to go to sleep? I've used lunesta and ambien with no effect. Has anyone tried some thing that even got close? F 50 4.5 years
1/14/2010
 4  Bipolar 1/Gen. Anxiety Disorder excessive sleeping, could sleep 12+ hours. withdrawl symptoms are terrible! This drug has been amazing. I also suffer from insomnia; and Seroquel, along with the Depakote puts me into a nice REM sleep. I'm easily affected by even the slightest change in dose though, which can throw off my sleeping pattern. Just make sure you don't take it too late or are taking too high of a mg at night time because it will knock you out. F 19 4 months
1/9/2010
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 4  Bipolar and maybe something else?? Well, I've only been on Seroquel for a few weeks. I'm taking 100mg a night. At first it made my heart beat really fast as soon as I took it, annd it knocked me out for 12 hrs, still does it I take the full thing. I have noticed though that parts of my body twitch?? And this drug also can cause tardive dyskinesia( so guys be carefull ) My hand and fingers twitch, and I have noticed that my eye lid at one point.. So maybe they have to lower my dose? Anyways other then that it balances out my moods but just have to be careful with taking it regularly and drinking etc. Puts my deamons to sleep <3 :) lol F 21 3 weeks
1/6/2010
 4  Sleep, Depression Zombie, Very compliant attitude, increased sex drive but no initiative to execute on this benefit. Some disorientation. Zone out at times. Some minor memory problems. About one hour after taking can have difficulty finding words or thinking complex thoughts. 50mg dose but have taken up to 300mg as needed. Only medicine I have ever taken that can give me some peace help me relax. M 58 2 years
12/20/2009
 4  insomnia, anxiety, depression a 'hungover' feeling the next day if i take it after 9.15pm the night before on 25mg and can fall asleep very easily with it so really great cure for insomnia F 23 2 months
12/9/2009
 4  Bipolar Depression / insomnia difficult to lose weight even while dieting, vivid dreams, and increased joint and muscle pain, even in my feet! I like Seroquel, because I can now sleep through the night at 50 mg Seroquel XR. Yes, I have vivid wierd dreams, but generally dont remember having them until I am trying to wake up the next a.m. For 6 years, I used to use a Tylenol PM for my insomnia. Tylenol PM can permanently hurt your liver, I think. I think using Seroquel is healthier than Tylenol PM. F 51 8 months
11/23/2009
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 4  Insomnia/Racing Thoughts/OCD I take this because my mind cannot stop the chatter at night. I have taken 100 mg one hour before bed and it has worked well for four years without having to increase the dose. I do take Restoril 30 mg when needed, which is rare and usually due to occasional back pain. The sedation wears off by the time I wake up. F 45 4 years
11/11/2009
 4  BPD (bi polar) Crazy dreams, I wake up groggy, however the feeling passes with a few cups of coffee. Besides that all side effects are good ones so far. I feel happy able to play with my kids, laugh and work with a clear mind. Used to want to drink alchol every day most often apon first waking up in the morning, now I couldn't be bothered to. Will update as I continue taking this medication,so far it has been a wonder.. F 25 2 months
11/8/2009
 4  Bi-polar disorder Slight weight gain, taken in conjunction with lithium. Intense grogginess and some unknown feelings of dread upon awakening. This passes as I arise and move about. I usually sleep at least 12 hours a night. Have been trying to awaken earlier, between 9&10AM by taking the drug at 7PM. Have some excessive muscle movements, and difficulty swallowing at night, which my doctor tells me could be a pre-cursor to Tardive Dyskenesia. I fear that, but am not ready to experiment with any of the newer classes of drugs for this disorder. I have Hyper-lipidemia have decided to take Niaspan (RX Niacin)in liew of statins. Not presently diagnosed with Diabetes, thankfully. I am a 62 year old female who has suffered with the symptoms of Bipolar Disorder for 40 years. I have a very strong family history of this disorder. The initial manifestation was about 4 months after the birth of my first child. It was in 1970 and was treated as Post Partum Depression. After moving about the country for the first 8 years of the onset of this disorder, I was formally diagnosed as having Bipolar Disorder. I was originally treated with major tranqualizors and was started on lithium in combo with antipsychotics and deseryl. In 2005 I moved to another state and my new doctor and I experimented with most of the usual antipsychotic drugs, all with disheartening side effects. About two years ago I was put on Seroquel and have taken as much as 600 mg in combo with smaller doses of lithium. I have recently decreased the dose of Seroquel to 450 mg and 300 mg of lithium. This combination seems to be working well for me and I am grateful for living in a time when these meds are so helpful. Hopefully, one day there will be a cure. F 62 2 years
10/23/2009
 4  Bi-polar constantly lethargic, sleeping upto 12 hours a day Has helped my mania tremendously. Just not sure how to stop sleeping so much. F 27 2 months
10/5/2009
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 4  Anxiety/depr./borderline dissociati Unfortunately, after about a year and a half of nearly miraculous help, I will need to stop this med because of uncontrollable weight gain, and concerns about diabetes, unless I can find a way to counteract the side effect. I understand that it changes the way the body metabolizes glucose. Diet change and exercise have not helped. After several years of uncontrollable anxiety and borderline dissociative episodes ( I felt like I was being possessed by a child-like part of myself, completely debilitating anxiety), and trying several different meds, having to detox off of addiction to benzos, which didnt completely cure me. then I was offered Seroquel, and I have felt better than I ever have in entire life. Have suffered low grade and sometimes more severe depression since a teen. This problem is genetic, at least 4 generations now. Unfortunately, it appears that the side effects are seriously dangerous to my health, with the possiblity of diabetes. I hope that I can find some alternative that works as well. I still recommend this medicine to anyone suffering severe uncontrollable anxiety and depression. It works different than other anti-depressants. Since I know how it works in the brain (what neurochemicals it affects) I can now go about finding a similar non-pharamceutical solution. F 48 1.5 years
9/26/2009
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 4  Severe depression/Anxiety/insomnia Drowsiness. Increased my appetite ten fold - always "starving". Best help for the insomnia I have ever had. Helps slightly with the anxiety - probably because of the drowsiness making me less aware - did not help the depression - must constantly fight an overwhelming urge to eat - all the time - or will blow up like a balloon. M 49 7 months
9/24/2009
 4  Anxiety/Bipolar/Insomnia weight LOSS, vivid nightmares, extreme grogginess in the morning for the first 2 weeks where i had to stay in bed most of the day, now it's just grogginess in the AM that goes away after coffee and time, the worst side effect has definately been the nightmares. I see so many bad comments about seroquel, which I understand..it is a very strong drug and you should not be on it unless you have a serious problem. I feel like many of these comments are made by people who probably didn't need the drug. It has changed my life. I'm surviving and prior to Seroquel i was near the end. F 22 6 months
9/11/2009
 4  Bipolar II, Acute Anxiety, Insomnia Deep sleep (Yay!), Moods (depression/hypomania) stabilized dramatically, INCREASED Libido, Increased Intensity of Orgasm(s). A little of my Hx: I'm a 26 y/o female, 5'2", 105 lbs. I've been seen/treated by many Psychiatrists and counselors since the age of 16 for Major Depressive Disorder, Acute Anxiety Disorder, and Chronic Insomnia. Over the years, I've taken every Antidepressant available (and combos of them), minus MAOI's - SSRI's all made the anxiety/insomnia worse and reduced my libido to 'nonexistent'; SNRI's worked for a while, then stopped being effective; Tricyclics made me sleep, but WAY too much - 18+ hrs q day; Atypical antidepressants just did NOT work for me. I finally got tired of "ping-ponging" from depression w/ suicidal ideation to 3-4 day episodes where I'd clean incessantly, not sleep, etc for those 72-96 hrs, and then crash back into the depression. I'm an RN, and several MD's I work with all highly recommended the same psychiatrist who's new to the area. I went into the first appt with a healthy skepticism - no one had ever helped me before, so why would this doctor be any different? WRONG! He was very thorough, thoughtful, and attentive. He Dx'ed me with Bipolar II (NOT Major Depressive Disorder) and agreed with the Acute Anxiety Disorder Dx. He rx'ed Seroquel 25mg HS (at bedtime), increased to 50mg HS week two IF NEEDED and Depakote ER 1000mg (and to continue Klonopin 1mg TID that I've been on since 1999). I've noticed a HUGE difference! I can sleep at night, my moods are stable, I feel better than I can ever remember feeling in my whole life! It's restored my sanity, my life, my marriage, my career, helps me enjoy my family, my 2-yr old daughter... I could go on and on! No weight gain or increased appetite, no hyperglycemia/diabetes, no increased cholesterol/triglycerides, etc. As I've researched Seroquel in the capacity of patient/RN, I've noticed that the VAST majority of patients who've had severe negative side effects from Seroquel are/were put on a grossly HIGH dosage, most not even titrated to that dose to see if a lower dose was adequate. I'm proof that, when given to the correct patient, wit F 26 3 months
9/9/2009
 4  Bipolar Mania, Anxiety, Insomnia * Twitching of hands involuntarily (not too often); forgetfulness of basic things; mild weight gain; heart palpitations at night - occurred 1 hour consistently after taking medication Overall, this medicine has worked wonders to help my anxiety/mania - I used to panic at the slightest thing, now it takes a very strong trigger to do it. It helps tremendously in the 'staying asleep' aspect, however, going to sleep is a bit of a nighmare because my heart feels like an electric shock 1 hour after taking medication. Only last about 5 - 10 minutes. F 30 2.5 years
9/5/2009
 4  Sleep Disorder, swing mood, depress It passes now one year taking 200mg seroquel. I feal emotional stable now but my weights rises up to 17kg in just 6 months. I sleep deep eatch night 12 to 14 hours. My colesterol LDL rises to mutch more 20% than the limit. Some times headakes and slow movements. I canīt sleep one night without seroquel. Im depending on it, its addicted. Memory loss with person names and recent life episods. My cocentration or focus is limited now, canīt read more than 3 pages in a book per day. Canīt watch a entire movie on cinema or TV. Canīt listen to peaple talks with full atention , its dispersss. Some times fiel strong and fast heart palpitations. Im 36, I change from risperidona to seroquel afther a 8 months stop treatment, just working at full time. I was very stress during last 2 months and when I decided to repeat treatment first day I take Seroquel this time, doctor advice for less side effects. I take the pill 300mg and afther 1 minute I drop down dead, with a very very fast heart beat, rise to 300 bpm. I call a ambulance emediatly to a friend near by. Then 3 minutes left my head was burning so hot, then I start not fealing my limbs, canīt move nothing at all in my body, not eaven a finger. Central nervs mal function or disconnected. Seeams I was dying. In my yeas I sow flashing lights strong. I feel I was dying. Later on some Ice on my head and some food keeps me alive for some 30 minuts before ambulance comes. I vigorate afther 1hour, I could walk again but with tremours in all my body. Still taking seroquel from then one year now with good results, but first take was shoking, as somebody have talk the same before in this rates... M 36 12 months
8/25/2009
 4   bi-polar Sleepiness is a big factor but i enjoy sleep and it doesn't get in the way too much. There is a slight increase in my appetite but I can easily control my hunger. The pill doesn't make you gain weight it's all about how you respond to your appetite. I am pretty satisfied with how it controlls my mood swings. I don't have my lows nearly as much as I used to. I would reccomend at least trying this medication. I almost didn't when i was reading posts on this website but i'm glad I did. Medication reacts differently to each and every person. If you have a problem with bi-polar the pros may greatly outway the cons. Good luck to everyone struggling. I know that this disorder is a bitch =) F 20 1 months
8/6/2009
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 4  BPD II Grogginess, especially in the mornings, when taking the first dose or when increasing dosage. Usually subisded a lot on second day and even lessened as I increased the dose. "Electric" feeling in my mouth. Anxiety attacks late in the day for first 5 days (subsided after that). Crying jags for the first 5 days. Suicidal ideation days 3-5 with strong thoughts of it around day 4 and 5. I was very, very afraid of this medicine. Everything I read, not published by the maker or someone associated with the maker, seemed to be negative. There are certainly some concerning side effects, but I was bound and determined to try to make it through the adjustment period of this medicine. I have had lots of bad experiences with SSRI type AD's and expected the worst with Seroquel. In fact, I started not to take the first dose because of all the negative publicity and feedback. I kept wanting to stop during the first 5 days, but didn't. I am really glad I didn't. I made it to the target dose of 300 mg per day and am almost side effect free. I still get the electric feeling in my mouth, get dry mouth, and am sometimes sleepy, but I am finally starting to see some relief from my depression, which I have NEVER experienced in my 42 years of life. This stuff is actually working and I am only a week in. Because optimal results are not seen until 2-6 weeks out, I am excited about what's to come. I may actually start to feel better. Bottom line, try this medicine if your pdoc thinks it might work for you. Don't be scared by the hype. Be cautious, but remember that these are new generation drugs that have less side effects than the older ones did. Watch your health and be vigilant, but don't let someone else's bad experience keep you from trying something that might help you free yourself from the bonds of depression. M 42 9 days
8/6/2009

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