ZYPREXA Reviews (OLANZAPINE)

Average Rating: 2.5 (585 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug

  

ZYPREXA  (OLANZAPINE):  Olanzapine is used to treat certain mental/mood conditions (such as schizophrenia, bipolar disorder). It may also be used in combination with other medication to treat depression. This medication can help to decrease hallucinations and help you to think more clearly and positively about yourself, feel less agitated, and take a more active part in everyday life. Olanzapine belongs to a class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain. Talk to the doctor about the risks and benefits of treatment (especially when used by teenagers). See also Precautions section.   FDA Approval Date: 1997-09-09 (Sources: U.S. Centers for Medicare Services, FDA)

  

Results are sorted by length of time drug was taken longest to shortest.

Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR ZYPREXACOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 4  bipolar Gained roughly 20 pounds , I rarely experience muscle cramps. At the start my legs twitched. This site has been a very reassuring to me ,to see how many people have gained weight. My doctor told me that my weight gain was from overeating but I eat normally and still gain weight. I have never gained weight in my life and after a couple of months on the drug I gained 20 pounds. I exercise regularly and still gain weight. I'm coming off in 6 months so hopefully then my body will balance itself out. M 24 1.5 years
2/28/2006
 4  olansapine Gained roughly 20 pounds , I rarely experience muscle cramps. At the start my legs twitched. This site has been a very reassuring to me ,to see how many people have gained weight. My doctor told me that my weight gain was from overeating but I eat normally and still gain weight. I have never gained weight in my life and after a couple of months on the drug I gained 20 pounds. I exercise regularly and still gain weight. I'm coming off in 6 months so hopefully then my body will balance itself out. M 1.5 years
2/28/2006
 3  schizoaffective insane amounts of weight gain - 70lbs in 1.5 years, spacing out (phasing out)-lack of creativity, non existent sexual drive - which my wife hated of course I have to say, despite its extremely negative side effects, this medication does wonders for paranoia and delusional thinking. I noticed the difference in 5 days of taking it after being off of it(stopped it abruptly by myself) The anxiety is non- existent now. I am able to function as a normal human being. M 26 1.5 years
2/26/2007
 3  BP aggitation/anxiety/irritability Very elevated blood sugar levels. Weight gain. I have been using Zyprexa on an "as needed" basis for the past 1.5 years. In the beginning, I rarely used it and waited until I was in a crisis. Now I try to head things off when I start to feel badly. I'm considering whether to take it every day or not. It has already raised my blood sugar levels to borderline diabetic while only taking 1/4 of a 2.5mg tablet, as needed - which has been anywhere from twice a week to twice a month. Previously I had low blood sugar. It does help my "spiraling out of control" feeling and aggitation/anxiety/anger/mania type phases. However, I have noticed that the more often I take it, it isn't as effective as before -- so, it seems that my body is getting used to the level and needs more. But, I don't want to gain a ton of weight ... and I've already gained about 5lbs in a month taking it occasionally at these really low (.75mg) doses. I will begin taking diabetes medicine next week to try and lower my blood sugar levels. F 43 1.5 years
12/10/2009
 2  Bipolar I during episodes. Weight gain. 10lbs a week. Sweet craving (VERY MUCH) I don't like it. It's slow and I need to be on it for at least 2 weeks for it to slowly bring down my episode. It doesn't affect sleep or anything, I just dislike it. Of course with such gain weight it was difficult. I thought I NEEDED it, and only IT but in fact there are other choices. I stick to the older anti=psychotics. It's just a matter of choice. They all have side effects, it's a Personal Matter. I'm sure it works great on some people and terrible on others. But if you start gaining weight on it very fast, think twice. or more! Don't say it's going to go away or i don't know. It likely won't. of course, exceptions :) I like the taste of the sublingual :) Good luck. F 25 1.5 years
11/24/2009
 1  Insomnia Inexplicable loss of weight, lost ability to sleep (wrecked sleep cicle), anhedonia, no libido, no orgasm, cant feel pleasure or excitation. This DRUG gave me a lactose intolerance. Only way to stop it is doing a slow taper (see the Asthon Manual for how to do it) with compounding pills and doing a specific diet. M 33 1.5 years
10 1X day
8/1/2021
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 5  depression with psychotic features Weight gain and diabetes, pituitary adenoma This was a good medicine for me for 8 years but now my physical health is in jeopardy. F 50 1 years
45 mg
11/11/2015
 5  Bipolar II Fatigue, lowered sex drive. I take 5mg/day. Very good drug. Its really good to prevent relapse into depression and it helps with anxiety. 30 1 years
4/2/2009
 5  Severe Anxiety with Agoraphobia Weight Gain of about 30 lbs. Everything just started tasting really good! This was ok for me though, because I was underweight to start with. I was a 21 year old college student who had to drop out of everything, because of the onset of a crippling anxiety disorder. I tried all of the usual SSRI drugs for several months with no improvement until my doctor prescribed me a small dose of Zyprexa. After only a few days, I started getting my ambition back, and began wanting to leave the house for the first time in months. Within 2 weeks, I felt like I was back to my old self again! This drug worked like a miracle for me. I thought I had lost my entire life before I started taking it. I was only on it for about a year until I was able to stop, and my symptoms have not returned. This drug will definitely increase your appreciation for food though! Beware! M 29 1 years
10/17/2007
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 5  schizoaffective disorder weight gain, hypersomnia (increased sleeping), calming of moods, general smoothing out of mania, calmness, less hallucinations. The positives definitely outweigh the negatives. 15MG per day helps me with my insomnia, helps silence the very negative and scary thoughts/voices. When taken with my antidepressant it helps my positive thoughts and moods. I give my thanks to Olanzapine/Zyprexa. F 33 1 years
3/6/2006
 5  OCD/Depression,Anxiety,Anorexia Wierd "spaced-out" moments, increased appetite, that's really it. AMAZING!! Pulled me from my hole like no other. Helps me immensely with my anxiety/panic. It was used to treat my Anorexia foremost. Really helped the negative thoughts and allowed me to begin to feel safe with eating again. I swear....if I am able to, I am never going off of this med. Thank you Zyprexa F 25 1 years
1/18/2007
 5  bipolar 1 Weight gain Zyprexa is an amazing drug. After trying numerous other meds, zyprexa is the only one that has kept my depression and mania from returning. The only side effect has been weight gain, which bothered me at first but I am used to it now. Overall, I think it is a great medication. F 29 1 years
10 mg 1X day
11/9/2011
 4  Psychotic Depression Weight Gain Zyprexa is amazing. It relieved me of my auditory and visual hallucinations, the only down side is weight gain. If I ate over 1400 calories a day I would gain weight, this was a battle for me because I have a very sweet tooth. Some days I would eat a little more than 1400 calories only to end up gaining a pound or two. In the end I lost the battle, the craving for sweet food became to much and the weight went on far to easy. I'm now on abilify which causes less weight gain than other atypical antipsychotics, on some sites it's even considered to be weight neutral. Overall I would say that Zyprexa is an amazing drug if you can mantain your weight on it but for me it was a constant battle. F 27 1 years
15MG 1X day
8/31/2012
 4  bipolar Groggy in the mornings; took 1/2hr+ to get up in morning and get moving. Gained 20-30#'s with NO a change in diet. (not eating more). Cholesterol levels went up to previously high levels even though am taking statins and cholesterol was down before. Slept great; like a rock, all the time. Went to sleep right away and slept through night. Started with Symbyax (10mg of Zyprexa, and prozac combined) Knocked me out and was falling asleep at work during the day. Went to 5mg of Zyprexa and cycled through several other antidepressants. At last was taking 5mg Zyprexa, 225mg Effexor and 300mg Wellbutrin. New pdoc has taken me off due to weight and cholesterol concerns- Now after 1 week, I have not slept more than 3-4 hours a night for last 5 nights. I go to sleep after a little time, so not insomnia per se. But I wake up in the middle of the night with night sweats and can't go back to sleep and so toss and turn the rest of the night. Have a headache, pressure in my head, and very sweaty palms, strange itching sensations. M 40 1 years
4/28/2006
 4  bipolar 1 Lots of weight gain! I ate a lot more, had a bigger appetite. Craved carbs and sugar.No other side effects. It works so well on my mania, anxiety, insomnia etc that I'm willing to deal with the weight gain. I try to resist carbs and sugar binges as much as I can. I'm afraid of the diabetes scare. F 46 1 years
9/11/2006
 4  bipolar 1 Weight gain like everybody does. I'm trying to FORCE myself away from the table since I've gained the weight because I EAT MORE. And I think it causes diabetes because I CRAVE sugar. Anyway, I love it and just wish it didn't cause weight gain and possibly diabetes. I'm staying with it for another year to see if I can drop some weight and level off. Seems that developing diabetes usually occurs within a year of starting, so I've passed that mark.It just works so well! F 46 1 years
9/11/2006
 4  Cyclothymia weight gain, unable to lose any weight. Lack of interest in sex, except during ovulation. Lighter, shorter periods (which I consider a blessing). Lack of motivation, even though I also take Adderall. Difficulty in getting up in the morning. Extreme craving for sugar...CONSTANTLY...so I guess it's also responsible for my constant breakouts. Little or no self control. Hard to feel things emotionally, especially romantically. Despite all its faults, I have to admit that Zyprexa has done a satisfactory job of repressing my Bipolar symptoms...I'd say it's been between 75 to 85 percent effective. I started out taking Symbyax. The Prozac part of it wasn't entirely successful at getting rid of my anxiety problems, however, so my doctor switched me to Zyprexa alone and put me on Paxil. The Paxil has done wonders, and I haven't had any side effects from it. I have been weaning myself off of Zyprexa gradually--without consulting my doctor-- as I can't fit into most of my clothes now, and feel like I must almost certainly be unhealthy due to my constant sugar consumption. Pretty much the only reason I eat "real" food is so I can get to dessert without anyone being on my case. And what's especially strange to me are the sudden urges to eat when I'm not hungry. When I first started taking Symbyax I went through 2 to 3 cartons of ice cream a week, by myself...and oddly enough it HAD to be Breyers cookies and F 39 1 years
10/5/2008
 4  Insomnia and psychotic disorder Decrease in libido. Sleepiness. Weight Gain. Was on Risperdal before Zyprexa. Used to get muscle spasms with risperdal. Also seriously affected my libido. No desire at all on Risperdal. Big improvement to libido on Zyprexa. Zyprexa really helped me sleep and I am functioning 100%. I have put on alot of weight, but this can be controlled through exercise. I've landed a job as a Systems Engineer in an aerospace company, and am handling it. My wife has been tremendously supportive. This has been a huge plus. Enjoy life, listen to your doc, exercise, and have patience. Try to keep your stress levels down, but don't let your illness stop you from doing the things you want to do. M 28 1 years
10/23/2007
 4  Anxiety, racing thoughts Weight gain, sleep a lot Has helped decrease racing thoughts, used to be on a higher dose but appetite was out of control and I gained 20 pounds but it has stabilized, does help me fall asleep F 27 1 years
2.5mg 1X day
3/12/2021
 3  bipolar as hell Went from 112 to 130 in 3 months wake up 3 am STARVING so I ate lol. But after I stopped taking it my bf and I realized I was a co,ok eye zombie and numb to everything it completely changed who I was F 28 1 years
5mg
8/2/2017

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