REXULTI Reviews

Average Rating: 2.9 (39 Ratings)

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 ANTIPSYCHOTICS ANTIMANICS

 Type: Rx Drug
  

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Key to Ratings: 1=LOW (I would not recommend taking this medicine.)
5=HIGH (this medicine cured me or helped me a great deal.)

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RATING  REASONSIDE EFFECTS FOR REXULTICOMMENTSSEXAGEDURATION/
DOSAGE
DATE ADDED
 
 1  Depression Felt great the first few weeks. But then the bottom fell out. Depression came back worst than when I started. Not able to control my emotions. M 49 60 days
1.5 mg 1X D
5/23/2021
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 4  Depression Weight gain !!! Increased cholesterol M 49 5 years
1.5 1X D
5/3/2021
 3  depression weight gain took away depression but gained 30 pounds ! F 60 30 days
30 mg 1X D
4/25/2021
 3  depression and anxiety I've been on Rexulti for four months. I've gained 20 pounds and I've experienced exhaustion that I didn't know was possible. It's very hard to get out of bed and do my job. I get ten plus hours of sleep a night and it's never enough. My depression is slightly better. F 49 4 days
1 mg 1X D
4/16/2021
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 3  Bipolar disorder and depression Weight gain, fatigue, food cravings, drowsiness It worked great at first but then I gained a bunch of weight. F 51 1 years
1mg 1X D
2/28/2021
 1  Anxiety/Panic Low BP, agitation, confusion, dizziness, no sex drive, no emotional output, no excitement Apparently It doesn't matter the mg your on. .25 mg is as low as it goes, this drug has almost ruined my life. I'm also on clonazepam for panic, Lamictal and lexapro. I'll take the extra anxiety and panic any day. Don't get me wrong it makes the obsessive thoughts go away but it has ruined my quality of life M 37 35 days
.25 1X D
2/14/2021
 1  Mood Stabilizer This medication caused migraine level headaches on a daily basis. Body was sore. It made depression worse. F 48 30 days
.5
1/24/2021
 1  Depression Mood swings, anger, tiredness hopelessness, more depressed Not happy. I was okay for the first few weeks then out of no where I became more depressed and very hostile. I became more depressed, anxious, and angry. Taking this drug makes me so tired and depressed I haven't even wanted to do the smallest of things. M 32 45 days
1mg 1X D
12/17/2020
 4  Anxiety and Depression I have struggled to find the right medications to aid to mental and physical wellness. Many medications has caused me symptoms that has been intolerable. I have only been using Rexulti and Viibryd for going on 2 months now and I can say that I am now stable, a bit more energetic and have more mental clarity. However I have experienced unwelcome weight gain and an increased appetite. This concerns me greatly because I don't want to go back to an obese life's style for the longevity of taking this medication. I have gain approximately 10 lbs in a short period of time. So, if you are concerned about her fitness health, this is not the medication for you. F 51 1 days
15mg 1X D
10/1/2020
 4  Anxiety and Depression I have struggled to find the right medications to aid to mental and physical wellness. Many medications has caused me symptoms that has been intolerable. I have only been using Rexulti and Viibryd for going on 2 months now and I can say that I am now stable, a bit more energetic and have more mental clarity. However I have experienced unwelcome weight gain and an increased appetite. This concerns me greatly because I don't want to go back to an obese life's style for the longevity of taking this medication. I have gain approximately 10 lbs in a short period of time. So, if you are concerned about her fitness health, this is not the medication for you. F 51 45 days
25mg 1X D
10/1/2020
 1  Anxiety First 2 weeks were great. Felt amazing. Like a switch went off and was in the clear. Then developed inner hostility, rage and irritability by week 3. Triggered a hypomanic episode and I don't have any mood disorder. Just severe anxiety. My cholesterol doubled, my BP which was normal required medication And I needed a statin. Gained 20lbs in 1 month. Off for 3 days and all the negative feelings are gone. I really thought this was the winner. Through it all, no anxiety. No panic. But made me so stressed and frustrated I had to stop it M 40 2 months
0.5 1X D
9/5/2020
 2  Bipolar Disorder Rexulti worked fine for my bipolar and eliminated all of my manic and depressive symptoms. However, almost from the beginning I experienced extreme fatigue. Fatigue is different from tiredness or drowsiness in that you have no energy or motivation all day long. Had to quit my part-time night job because I was too tired to finish out the day. My doctor foolishly had me on the highest dose (4mg), which is for schizophrenia, so I weaned myself down to 2 mg, then 1 mg, then .5. Made no difference. Got to the point where I was so fatigued I couldn't get out of bed at all. Couldn't do simple household chores or grocery shopping or my daytime job (I work from home so have flexible hours). The only way I got my energy back was to stop Rexulti completely. Then all my energy and motivation returned within a week. Tried other antipsychotics but I had very poor reaction. So, started the Rexulti again at low dose of 1 mg, but fatigue returned same as before. Now I have stopped it again due to this intolerable side effect. Note: not everyone experiences fatigue from antipsychotics, but it is a known side effect of anti-psychotics and antidepressants. If you are susceptible to this side effect, then Rexulti will hit you hard. So unfortunate, because otherwise a very effective drug. I did not experience weight gain but I did have some cravings for carbohydrates. Finally there is no generic of this drug, so my cost for 30 tablets was $186 with insurance. Good, effective drug for bipolar disorder, although it was not designed for this. Used as a mood stabilizer in conjunction with an antidepressant (Trintellix). Extreme fatigue a potential side effect but this depends on individual physiology. F 68 1 years
4mg 1X D
7/19/2020
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 1  Treatment resistant MDD Horrible withdrawal side effects despite a very slow taper extreme nausea, emotionally flat, no pleasure and no sadness. No motivation to engage in any activity. After effects not worth it. F 62 45 days
1 1X D
7/19/2020
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 1  MDD Tingling in face and tongue, sleepiness, fatigue, increased appetite F 48 4 weeks
.5mg 1X D
7/17/2020
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 3  Bipolar II Depression I gained ten pounds on it; not much but I am small so it seemed like a lot. My cholesterol was already high but this med sent it to 260. The worst side effect was withdrawal dyskinesia and akathesia. This is different from tardive dyskinesia in that it came on AFTER I stopped the drug, which masked it as it developed. Now, I have uncontrollable movements of my tongue and jaw, constantly sucking, chewing and swallowing. As a result my teeth are getting sensitive, my jaw is clenched and sore and I actually have calluses on my tongue. I also rock when I sit and can't stop jiggling my right leg. I can stop these symptoms temporarily if I really really concentrate, but I can't keep my attention on them all the time. I am afraid the dyskinesia may be permanent. Sometimes it is. I think it did help with my mood swings but had a general flattening effect. I stopped it for the weight gain and cholesterol issues, but had no idea it had damaged me so. These side effects can occur with this whole family of antipsychotics. Judge for yourself if the risks outweigh the benefits. I will never take them again. 59 4 years
3 1X D
7/5/2020
 3  Major depressive disorder Worked well at first, noticed increased hunger and gained 30 pounds in less than 3 weeks. My health declined, sex was a chore, constantly sleepy. Too tired to even do minuscule tasks around the house. Felt like more of a bump on a log than I did while depressed. Even my adderall couldn't keep me awake and focused anymore while taking rexulti. Would fall asleep on 40 mg of adderall. Not worth it if you are only dealing with depression and anxiety F 28 8 months
.50 mg
6/17/2020
 1  Depression Anxiety increased, constant feeling of dread but no insight into the idea that the medication could be causing it. Stopped immediately after stopping drug... M 39 30 days
0.25-0.5
6/4/2020
 3  Anxiety; Depression 1mg unable to keeps my eyes open extreme fatigue Great at removing the gray cloud and controlling my anxiety but now I'm in a sleepy cloud all day. F 45 44 days
1 mg
5/12/2020
 2  Deep depression EXTREMELY TIRED. I can't wake up the next day without feeling like I have a drug hangover. Meanwhile, all "bad" thoughts have gone away due to feeling numb almost from the medication. This has been added on to my 40mg of celexa and 40mg of adderall per the day. I'm completely useless. F 33 7 days
.5 mg
4/29/2020
 5  mdd calmness good drug but expensive M 44 30 days
1mg 1X D
1/7/2020
  

REXULTI  (BREXPIPRAZOLE):  This medication is used to treat certain mental/mood disorders (such as schizophrenia, depression). Brexpiprazole helps you to think more clearly, feel less nervous, and take part in everyday life. It may also help to decrease hallucinations (hearing/seeing things that are not there). In addition, this medication may improve your mood, sleep, appetite, and energy level. Brexpiprazole is a psychiatric medication that belongs to the class of drugs called atypical antipsychotics. It works by helping to restore the balance of certain natural substances in the brain.   (Sources: U.S. Centers for Medicare Services, FDA)

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